{"id":"https://openalex.org/W2003228769","doi":"https://doi.org/10.1016/0006-3002(62)91103-4","title":"The effect of tryptophan and methyltryptophans on submerged lysergic acid fermentation byClaviceps paspall Stevens and Hall","display_name":"The effect of tryptophan and methyltryptophans on submerged lysergic acid fermentation byClaviceps paspall Stevens and Hall","publication_year":1962,"publication_date":"1962-01-01","ids":{"openalex":"https://openalex.org/W2003228769","doi":"https://doi.org/10.1016/0006-3002(62)91103-4","mag":"2003228769","pmid":"https://pubmed.ncbi.nlm.nih.gov/13862059"},"language":"en","primary_location":{"id":"doi:10.1016/0006-3002(62)91103-4","doi":"https://doi.org/10.1016/0006-3002(62)91103-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-3002(62)91103-4","pdf_url":null,"source":{"id":"https://openalex.org/S41066938","display_name":"Biochimica et Biophysica Acta","issn_l":"0006-3002","issn":["0006-3002","1878-2434"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113580571","display_name":"Federico Arcamone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F. Arcamone","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108629317","display_name":"Ernst Boris Chain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E.B. Chain","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067948856","display_name":"A. Ferretti","orcid":"https://orcid.org/0000-0001-5161-1686","observed_orcids":["https://orcid.org/0000-0001-5161-1686"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Ferretti","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062835055","display_name":"Anacleto Minghetti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Minghetti","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028121921","display_name":"P. Pennella","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P. Pennella","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"last","author":{"id":null,"display_name":"A. Tonolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Tonolo","raw_affiliation_strings":["International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Chemical Microbiology, Istituto Superiore di Sanit\u00e0, Rome Italy","institution_ids":["https://openalex.org/I27897274"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I27897274"],"apc_list":null,"apc_paid":null,"fwci":4.0729,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.92898273,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"57","issue":"1","first_page":"174","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.7285000085830688,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.7285000085830688,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10520","display_name":"Mycotoxins in Agriculture and Food","score":0.18369999527931213,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":0.015200000256299973,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lysergic-acid","display_name":"lysergic acid","score":0.9409999847412109},{"id":"https://openalex.org/keywords/tryptophan","display_name":"tryptophan","score":0.8500000238418579},{"id":"https://openalex.org/keywords/asparagine","display_name":"asparagine","score":0.765999972820282},{"id":"https://openalex.org/keywords/nitrogen-source","display_name":"nitrogen source","score":0.878000020980835},{"id":"https://openalex.org/keywords/alkaloid-production","display_name":"alkaloid production","score":0.7820000052452087},{"id":"https://openalex.org/keywords/ammonia-assimilation","display_name":"ammonium assimilation","score":0.8600000143051147},{"id":"https://openalex.org/keywords/glutamine-synthetase","display_name":"glutamine synthetase","score":0.8360000252723694},{"id":"https://openalex.org/keywords/alanine-dehydrogenase","display_name":"alanine dehydrogenase","score":0.8809999823570251},{"id":"https://openalex.org/keywords/glutamate-synthase","display_name":"glutamate synthase","score":0.9710000157356262},{"id":"https://openalex.org/keywords/fungal-fermentation","display_name":"fungal fermentation","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C2775895851","wikidata":"https://www.wikidata.org/wiki/Q185906","display_name":"Asparagine","level":3,"score":0.717164158821106},{"id":"https://openalex.org/C2777202666","wikidata":"https://www.wikidata.org/wiki/Q417383","display_name":"Glutamate dehydrogenase","level":4,"score":0.708844780921936},{"id":"https://openalex.org/C2779870022","wikidata":"https://www.wikidata.org/wiki/Q190901","display_name":"Ammonium","level":2,"score":0.579770565032959},{"id":"https://openalex.org/C75520062","wikidata":"https://www.wikidata.org/wiki/Q15321392","display_name":"NAD+ kinase","level":3,"score":0.5565497279167175},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.5377974510192871},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5359581112861633},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.491629421710968},{"id":"https://openalex.org/C2779856020","wikidata":"https://www.wikidata.org/wiki/Q218642","display_name":"Alanine","level":3,"score":0.46273359656333923},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.44656944274902344},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.44583040475845337},{"id":"https://openalex.org/C2777667214","wikidata":"https://www.wikidata.org/wiki/Q70702","display_name":"Alkaloid","level":2,"score":0.436631441116333},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.42248764634132385},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.32276463508605957},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.27961814403533936},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.24623817205429077},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14362382888793945},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002967","descriptor_name":"Claviceps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008237","descriptor_name":"Lysergic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008238","descriptor_name":"Lysergic Acid Diethylamide","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-3002(62)91103-4","doi":"https://doi.org/10.1016/0006-3002(62)91103-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-3002(62)91103-4","pdf_url":null,"source":{"id":"https://openalex.org/S41066938","display_name":"Biochimica et Biophysica Acta","issn_l":"0006-3002","issn":["0006-3002","1878-2434"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta","raw_type":"journal-article"},{"id":"pmid:13862059","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13862059","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1976660021","https://openalex.org/W1979596590","https://openalex.org/W1986326428","https://openalex.org/W2026591913","https://openalex.org/W2036171952","https://openalex.org/W2059570265","https://openalex.org/W2060902572","https://openalex.org/W2069368103","https://openalex.org/W2159972420"],"related_works":["https://openalex.org/W1975153237","https://openalex.org/W1983978159","https://openalex.org/W1988750010","https://openalex.org/W2093465342","https://openalex.org/W1982781268","https://openalex.org/W2593670581","https://openalex.org/W1995523432","https://openalex.org/W2592892972","https://openalex.org/W1553192144","https://openalex.org/W2067755843"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}