{"id":"https://openalex.org/W2003201586","doi":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","title":"Too Good to Treat? Outcomes in Patients Not Receiving Thrombolysis Due to Mild Deficits or Rapidly Improving Symptoms","display_name":"Too Good to Treat? Outcomes in Patients Not Receiving Thrombolysis Due to Mild Deficits or Rapidly Improving Symptoms","publication_year":2011,"publication_date":"2011-11-22","ids":{"openalex":"https://openalex.org/W2003201586","doi":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","mag":"2003201586","pmid":"https://pubmed.ncbi.nlm.nih.gov/22103880","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3296877"},"language":"en","primary_location":{"id":"doi:10.1111/j.1747-4949.2011.00696.x","doi":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","pdf_url":null,"source":{"id":"https://openalex.org/S150089136","display_name":"International Journal of Stroke","issn_l":"1747-4930","issn":["1747-4930","1747-4949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Stroke","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3296877","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077859725","display_name":"Joshua Zebadiah Willey","orcid":"https://orcid.org/0000-0001-5180-2044","observed_orcids":["https://orcid.org/0000-0001-5180-2044"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Z. Willey","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108527619","display_name":"Joshua I. Stillman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Stillman","raw_affiliation_strings":["Department of Emergency Medicine, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006104235","display_name":"Juan Rivolta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan A. Rivolta","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022583053","display_name":"Julio R. Vieira","orcid":"https://orcid.org/0009-0005-7772-6146","observed_orcids":["https://orcid.org/0009-0005-7772-6146"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julio Vieira","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101886795","display_name":"Margaret M. Doyle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret M. Doyle","raw_affiliation_strings":["Department of Biostatistics, Mailman School of Public Health, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Mailman School of Public Health, New York, NY, USA","institution_ids":["https://openalex.org/I57206974","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067350514","display_name":"Guillermo Linares","orcid":"https://orcid.org/0000-0003-2810-658X","observed_orcids":["https://orcid.org/0000-0003-2810-658X"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guillermo Linares","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029809086","display_name":"Adrian Marchidann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrian Marchidann","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113514048","display_name":"Mitchell S.V. Elkind","orcid":"https://orcid.org/0000-0003-2562-1156","observed_orcids":["https://orcid.org/0000-0003-2562-1156"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell S. V. Elkind","raw_affiliation_strings":["Department of Epidemiology, Mailman School of Public Health, New York, NY, USA","Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Mailman School of Public Health, New York, NY, USA","institution_ids":["https://openalex.org/I57206974","https://openalex.org/I78577930"]},{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038584263","display_name":"Bernadette M Boden-Albala","orcid":"https://orcid.org/0000-0002-3752-329X","observed_orcids":["https://orcid.org/0000-0002-3752-329X"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bernadette Boden-Albala","raw_affiliation_strings":["Department of Socio-medical Sciences, Mailman School of Public Health, New York, NY, USA","Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Socio-medical Sciences, Mailman School of Public Health, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088034421","display_name":"Randolph S. Marshall","orcid":"https://orcid.org/0000-0003-3037-0283","observed_orcids":["https://orcid.org/0000-0003-3037-0283"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randolph S. Marshall","raw_affiliation_strings":["Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Stroke, Department of Neurology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":3.601,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.92188045,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"7","issue":"3","first_page":"202","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9039999842643738},{"id":"https://openalex.org/keywords/thrombolysis","display_name":"thrombolysis","score":0.902999997138977},{"id":"https://openalex.org/keywords/early-neurological-deterioration","display_name":"early neurological deterioration","score":0.8679999709129333},{"id":"https://openalex.org/keywords/minor-stroke","display_name":"minor stroke","score":0.722000002861023},{"id":"https://openalex.org/keywords/stroke-severity","display_name":"stroke severity","score":0.40299999713897705},{"id":"https://openalex.org/keywords/nihss","display_name":"NIHSS","score":0.45399999618530273},{"id":"https://openalex.org/keywords/modified-rankin-scale","display_name":"modified Rankin Scale","score":0.875},{"id":"https://openalex.org/keywords/discharge-disposition","display_name":"discharge disposition","score":0.9010000228881836},{"id":"https://openalex.org/keywords/history-of-stroke","display_name":"stroke history","score":0.6959999799728394},{"id":"https://openalex.org/keywords/treatment-decision-making","display_name":"treatment decision-making","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.945235013961792},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.8234469890594482},{"id":"https://openalex.org/C2780931571","wikidata":"https://www.wikidata.org/wiki/Q568775","display_name":"Modified Rankin Scale","level":4,"score":0.7821347713470459},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.7221750617027283},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.4922613203525543},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4685453176498413},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4457295536994934},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38258492946624756},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.36932241916656494},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.2968158721923828},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22057566046714783},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18561354279518127},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.14176377654075623},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1747-4949.2011.00696.x","doi":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1747-4949.2011.00696.x","pdf_url":null,"source":{"id":"https://openalex.org/S150089136","display_name":"International Journal of Stroke","issn_l":"1747-4930","issn":["1747-4930","1747-4949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Stroke","raw_type":"journal-article"},{"id":"pmid:22103880","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22103880","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of stroke : official journal of the International Stroke Society","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2607346","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3296877","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3296877","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3296877","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Int J Stroke","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2607346","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3296877","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Reduced inequalities","score":0.699999988079071,"id":"https://metadata.un.org/sdg/10"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2900118815","display_name":"New York Columbia Collaborative SPOTRIAS","funder_award_id":"P50NS049060","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6899856684","display_name":"Neuro-vascular Disease as a Cause of Impaired Mobility","funder_award_id":"K23NS073104","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7410483342","display_name":null,"funder_award_id":"L30 AG031009","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332502","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1985599318","https://openalex.org/W1994867854","https://openalex.org/W1998257407","https://openalex.org/W2056811784","https://openalex.org/W2061599477","https://openalex.org/W2063544001","https://openalex.org/W2090041713","https://openalex.org/W2091284575","https://openalex.org/W2107181967","https://openalex.org/W2115858038","https://openalex.org/W2129182830","https://openalex.org/W2133758580","https://openalex.org/W2134002354","https://openalex.org/W2135244516","https://openalex.org/W2138595885","https://openalex.org/W2141132646","https://openalex.org/W2150052630","https://openalex.org/W2150666419","https://openalex.org/W2169768639","https://openalex.org/W2292308933","https://openalex.org/W4245948508","https://openalex.org/W4251445510"],"related_works":["https://openalex.org/W2207072045","https://openalex.org/W2551725040","https://openalex.org/W1985599318","https://openalex.org/W2331236633","https://openalex.org/W1977429084","https://openalex.org/W7096975440","https://openalex.org/W1558380271","https://openalex.org/W2296827538","https://openalex.org/W2056811784","https://openalex.org/W2023054375"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Among":[1],"ischemic":[2],"stroke":[3,68,188,250],"patients":[4,51,69,121,215,228,251,264],"arriving":[5],"within":[6,76,124],"the":[7,40,73,87,135,254,278,281],"treatment":[8],"window,":[9],"rapidly":[10],"improving":[11],"symptoms":[12],"or":[13],"having":[14],"a":[15,24,53,163,177,203,224],"mild":[16,249],"deficit":[17],"(i.e.":[18],"too":[19,47,129,230],"good":[20,48,130,231],"to":[21,49,72,96,131,156,232,241,247,272],"treat)":[22],"is":[23],"common":[25],"reason":[26,137],"for":[27,138],"exclusion.":[28],"Several":[29],"studies":[30],"have":[31,235,266],"reported":[32],"poor":[33],"outcomes":[34,99],"in":[35,46,52,66,86,239],"this":[36],"group.":[37],"We":[38,221],"addressed":[39],"question":[41],"of":[42,90,104,147,165,168,180,207,227,280],"early":[43,236],"neurological":[44,237],"deterioration":[45],"treat":[50,132,233,248],"larger":[54],"prospective":[55],"cohort":[56],"study.":[57],"METHODS:":[58],"Admission":[59],"and":[60,113,173,212,283],"discharge":[61,101,114,193,204,261],"information":[62],"were":[63,100,216],"collected":[64],"prospectively":[65],"acute":[67],"who":[70,122,265],"presented":[71,123],"emergency":[74],"room":[75],"three-hours":[77],"from":[78,94],"onset.":[79],"The":[80,270],"primary":[81],"outcome":[82,255],"measure":[83,256],"was":[84,195],"change":[85],"National":[88,102,145,166,178,205],"Institutes":[89,103,146,167,179,206],"Health":[91,105,148,169,181,208],"Stroke":[92,106,149,170,182,209],"Scale":[93,107,150,171,183,210],"baseline":[95],"discharge.":[97],"Secondary":[98],">4,":[108,211],"not":[109,139,217],"being":[110],"discharged":[111,218],"home,":[112],"modified":[115],"Rankin":[116],"scale.":[117],"RESULTS:":[118],"Of":[119],"355":[120],"three-hours,":[125],"127":[126],"(35\u00b78%)":[127],"had":[128,176,202,267],"listed":[133],"as":[134],"only":[136,199],"receiving":[140],"thrombolysis,":[141],"with":[142],"median":[143],"admission":[144],"=":[151,154,191],"1":[152],"(range":[153],"0":[155],"19).":[157],"At":[158],"discharge,":[159],"seven":[160],"(5\u00b75%)":[161],"showed":[162],"worsening":[164],"\u22651,":[172],"nine":[174],"(7\u00b71%)":[175],">4.":[184],"When":[185],"excluding":[186],"prior":[187,268],"(remaining":[189],"n":[190],"97),":[192],"status":[194],"even":[196],"more":[197],"benign:":[198],"five":[200],"(5\u00b72%)":[201],"two":[213],"(2\u00b71%)":[214],"home.":[219],"CONCLUSION:":[220],"found":[222],"that":[223],"small":[225],"proportion":[226],"deemed":[229],"will":[234],"deterioration,":[238],"contrast":[240],"other":[242],"studies.":[243],"Decisions":[244],"about":[245],"whether":[246],"depend":[252],"on":[253,277],"chosen,":[257],"particularly":[258],"when":[259],"considering":[260],"disposition":[262],"among":[263],"stroke.":[269],"decision":[271],"thrombolyze":[273],"may":[274],"ultimately":[275],"rest":[276],"nature":[279],"presentation":[282],"deficit.":[284]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}