{"id":"https://openalex.org/W2003188632","doi":"https://doi.org/10.1016/j.crvi.2004.10.009","title":"Parkinson's disease: from causes to mechanisms","display_name":"Parkinson's disease: from causes to mechanisms","publication_year":2004,"publication_date":"2004-12-19","ids":{"openalex":"https://openalex.org/W2003188632","doi":"https://doi.org/10.1016/j.crvi.2004.10.009","mag":"2003188632","pmid":"https://pubmed.ncbi.nlm.nih.gov/15770999"},"language":"en","primary_location":{"id":"doi:10.1016/j.crvi.2004.10.009","doi":"https://doi.org/10.1016/j.crvi.2004.10.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.crvi.2004.10.009","pdf_url":null,"source":{"id":"https://openalex.org/S119003425","display_name":"Comptes Rendus Biologies","issn_l":"1631-0691","issn":["1631-0691","1768-3238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ddh","doaj","dongbi-d","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4404678052","host_organization_name":"Acad\u00e9mie des sciences","host_organization_lineage":["https://openalex.org/P4404678052"],"host_organization_lineage_names":["Acad\u00e9mie des sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comptes Rendus. Biologies","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001223233","display_name":"Olga Corti","orcid":"https://orcid.org/0000-0003-2093-7389","observed_orcids":["https://orcid.org/0000-0003-2093-7389"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Olga Corti","raw_affiliation_strings":["INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cornelia Hampe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cornelia Hampe","raw_affiliation_strings":["INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073522540","display_name":"Frederic D. Darios","orcid":"https://orcid.org/0000-0001-9800-5990","observed_orcids":["https://orcid.org/0000-0001-9800-5990"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9ric Darios","raw_affiliation_strings":["INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082434708","display_name":"Pablo Ib\u00e1\u00f1ez","orcid":"https://orcid.org/0000-0002-2197-1194","observed_orcids":["https://orcid.org/0000-0002-2197-1194"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pablo Ibanez","raw_affiliation_strings":["INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075704131","display_name":"Merle Ruberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Merle Ruberg","raw_affiliation_strings":["INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027489586","display_name":"Alexis Brice","orcid":"https://orcid.org/0000-0002-0941-3990","observed_orcids":["https://orcid.org/0000-0002-0941-3990"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4405275326","display_name":"Physiopathologie des Comportements","ror":"https://ror.org/03ct18y90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405275326"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Alexis Brice","raw_affiliation_strings":["D\u00e9partement de g\u00e9n\u00e9tique, cytog\u00e9n\u00e9tique et embryologie, groupe hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de g\u00e9n\u00e9tique, cytog\u00e9n\u00e9tique et embryologie, groupe hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I4210121705"]},{"raw_affiliation_string":"INSERM U 289, h\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re, 47, bd de l'H\u00f4pital, 75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5027489586"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210121705","https://openalex.org/I4405275326"],"apc_list":null,"apc_paid":null,"fwci":0.7043,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.52783964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"328","issue":"2","first_page":"131","last_page":"142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13991","display_name":"Nuclear Receptors and Signaling","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.8199999928474426},{"id":"https://openalex.org/keywords/etiology","display_name":"etiology","score":0.6449999809265137},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7329999804496765},{"id":"https://openalex.org/keywords/environmental-toxicants","display_name":"environmental toxins","score":0.871999979019165},{"id":"https://openalex.org/keywords/neurotoxins","display_name":"neurotoxins","score":0.878000020980835},{"id":"https://openalex.org/keywords/nigrostriatal-pathway","display_name":"nigrostriatal pathway","score":0.9599999785423279},{"id":"https://openalex.org/keywords/mitochondrial-function","display_name":"mitochondrial function","score":0.625},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.7434022426605225},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6911794543266296},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.6698201298713684},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5828462839126587},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5345268845558167},{"id":"https://openalex.org/C2777427615","wikidata":"https://www.wikidata.org/wiki/Q954257","display_name":"Degenerative disease","level":3,"score":0.4950029253959656},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48310160636901855},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.42619097232818604},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.4226870834827423},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34471631050109863},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3436611294746399},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.2564171850681305},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21781304478645325},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13879871368408203}],"mesh":[{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013378","descriptor_name":"Substantia Nigra","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051843","descriptor_name":"Synucleins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.crvi.2004.10.009","doi":"https://doi.org/10.1016/j.crvi.2004.10.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.crvi.2004.10.009","pdf_url":null,"source":{"id":"https://openalex.org/S119003425","display_name":"Comptes Rendus Biologies","issn_l":"1631-0691","issn":["1631-0691","1768-3238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ddh","doaj","dongbi-d","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4404678052","host_organization_name":"Acad\u00e9mie des sciences","host_organization_lineage":["https://openalex.org/P4404678052"],"host_organization_lineage_names":["Acad\u00e9mie des sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comptes Rendus. Biologies","raw_type":"journal-article"},{"id":"pmid:15770999","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15770999","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comptes rendus biologies","raw_type":"Journal Article"},{"id":"pmh:oai:centre-mersenne.org:CRBIOL_2005__328_2_131_0","doi":null,"is_oa":false,"landing_page_url":"https://comptes-rendus.academie-sciences.fr/biologies/articles/10.1016/j.crvi.2004.10.009/","pdf_url":null,"source":{"id":"https://openalex.org/S4377196241","display_name":"Biology Reports","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":127,"referenced_works":["https://openalex.org/W62603772","https://openalex.org/W114033643","https://openalex.org/W1485468448","https://openalex.org/W1503570667","https://openalex.org/W1503846663","https://openalex.org/W1504584187","https://openalex.org/W1507318381","https://openalex.org/W1511827873","https://openalex.org/W1521854746","https://openalex.org/W1527671059","https://openalex.org/W1529474377","https://openalex.org/W1550876205","https://openalex.org/W1564437189","https://openalex.org/W1584829548","https://openalex.org/W1591724033","https://openalex.org/W1618846043","https://openalex.org/W1806592592","https://openalex.org/W1811548175","https://openalex.org/W1877873625","https://openalex.org/W1923453730","https://openalex.org/W1965778124","https://openalex.org/W1969800514","https://openalex.org/W1969950937","https://openalex.org/W1972939055","https://openalex.org/W1974208595","https://openalex.org/W1974379210","https://openalex.org/W1976316003","https://openalex.org/W1976345822","https://openalex.org/W1976749972","https://openalex.org/W1976923181","https://openalex.org/W1979527613","https://openalex.org/W1981862471","https://openalex.org/W1986188355","https://openalex.org/W1988457275","https://openalex.org/W1994452430","https://openalex.org/W2000778500","https://openalex.org/W2002867487","https://openalex.org/W2004600163","https://openalex.org/W2008748100","https://openalex.org/W2009556855","https://openalex.org/W2010612415","https://openalex.org/W2011339216","https://openalex.org/W2011603170","https://openalex.org/W2013468767","https://openalex.org/W2019978095","https://openalex.org/W2020796799","https://openalex.org/W2024041381","https://openalex.org/W2024891592","https://openalex.org/W2025383404","https://openalex.org/W2025748949","https://openalex.org/W2025922492","https://openalex.org/W2030857589","https://openalex.org/W2031898930","https://openalex.org/W2034692278","https://openalex.org/W2035531816","https://openalex.org/W2039824115","https://openalex.org/W2045062740","https://openalex.org/W2047211900","https://openalex.org/W2049161582","https://openalex.org/W2053784053","https://openalex.org/W2055124287","https://openalex.org/W2056823686","https://openalex.org/W2059362512","https://openalex.org/W2059737503","https://openalex.org/W2064996887","https://openalex.org/W2066433054","https://openalex.org/W2066842081","https://openalex.org/W2068806054","https://openalex.org/W2069403245","https://openalex.org/W2071881564","https://openalex.org/W2073351779","https://openalex.org/W2075302437","https://openalex.org/W2076344205","https://openalex.org/W2077032680","https://openalex.org/W2077260129","https://openalex.org/W2079536916","https://openalex.org/W2081599984","https://openalex.org/W2082535345","https://openalex.org/W2088962120","https://openalex.org/W2089094066","https://openalex.org/W2091265794","https://openalex.org/W2092791231","https://openalex.org/W2098525070","https://openalex.org/W2100898704","https://openalex.org/W2101362932","https://openalex.org/W2104382960","https://openalex.org/W2104912043","https://openalex.org/W2106252778","https://openalex.org/W2107977469","https://openalex.org/W2109040303","https://openalex.org/W2114881821","https://openalex.org/W2117742059","https://openalex.org/W2118219252","https://openalex.org/W2120699008","https://openalex.org/W2120706471","https://openalex.org/W2120867735","https://openalex.org/W2123431154","https://openalex.org/W2129248872","https://openalex.org/W2131256783","https://openalex.org/W2131365535","https://openalex.org/W2132181394","https://openalex.org/W2133550059","https://openalex.org/W2133865158","https://openalex.org/W2136388422","https://openalex.org/W2140647923","https://openalex.org/W2142780460","https://openalex.org/W2145683656","https://openalex.org/W2148869194","https://openalex.org/W2150656456","https://openalex.org/W2154737306","https://openalex.org/W2154761807","https://openalex.org/W2155977379","https://openalex.org/W2158259597","https://openalex.org/W2166046424","https://openalex.org/W2171205749","https://openalex.org/W2171281715","https://openalex.org/W2171873547","https://openalex.org/W2317804643","https://openalex.org/W2573367782","https://openalex.org/W2616047064","https://openalex.org/W4246429373","https://openalex.org/W4254053338","https://openalex.org/W4296217171","https://openalex.org/W4296930794","https://openalex.org/W4297062289","https://openalex.org/W4319425454","https://openalex.org/W6638270128"],"related_works":["https://openalex.org/W2029249465","https://openalex.org/W2018211893","https://openalex.org/W1185315863","https://openalex.org/W2492102828","https://openalex.org/W2524217487","https://openalex.org/W2769172998","https://openalex.org/W4296355802","https://openalex.org/W2164728918","https://openalex.org/W2055032992","https://openalex.org/W7096566027"],"abstract_inverted_index":{"Parkinson's":[0],"disease":[1,9],"(PD)":[2],"is":[3,66],"a":[4],"common":[5],"age-related,":[6],"progressive":[7],"neurodegenerative":[8],"of":[10,24,30,56,72,74,91],"unknown":[11],"etiology.":[12],"Environmental":[13],"factors":[14],"have":[15,50],"long":[16],"been":[17,51],"suspected":[18],"to":[19,27],"participate":[20],"in":[21,84],"the":[22,28,35,40,47,54,70,88],"pathogenesis":[23],"PD":[25],"due":[26],"existence":[29],"neurotoxins":[31],"that":[32,69],"preferentially":[33],"damage":[34],"dopaminergic":[36],"nigrostriatal":[37],"pathway.":[38],"In":[39],"past":[41],"few":[42],"years,":[43],"novel":[44],"insights":[45],"into":[46],"degenerative":[48],"process":[49],"provided":[52],"by":[53],"discovery":[55],"genes":[57,76],"responsible":[58],"for":[59],"rare":[60],"monogenic":[61],"parkinsonian":[62],"syndromes.":[63],"Compelling":[64],"evidence":[65],"accumulating,":[67],"suggesting":[68],"products":[71],"several":[73],"these":[75],"can":[77],"interact":[78],"with":[79],"environmental":[80],"toxins":[81],"and":[82],"intervene":[83],"molecular":[85],"pathways":[86],"controlling":[87],"functional":[89],"integrity":[90],"mitochondria.":[92]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
