{"id":"https://openalex.org/W2003176267","doi":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","title":"Depression and Anxiety in Patients with Epilepsy","display_name":"Depression and Anxiety in Patients with Epilepsy","publication_year":2001,"publication_date":"2001-03-01","ids":{"openalex":"https://openalex.org/W2003176267","doi":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","mag":"2003176267","pmid":"https://pubmed.ncbi.nlm.nih.gov/11422352"},"language":"en","primary_location":{"id":"doi:10.1046/j.1528-1157.2001.00510.x","doi":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","pdf_url":null,"source":{"id":"https://openalex.org/S203153751","display_name":"Epilepsia","issn_l":"0013-9580","issn":["0013-9580","1528-1157","1528-1167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036504927","display_name":"Ada Piazzini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086830","display_name":"Ospedale San Paolo","ror":"https://ror.org/0026m8b31","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I4210086830"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ada Piazzini","raw_affiliation_strings":["Epilepsy Center, S. Paolo Hospital, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Center, S. Paolo Hospital, Milan, Italy","institution_ids":["https://openalex.org/I4210086830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019481375","display_name":"Raffaele Canger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086830","display_name":"Ospedale San Paolo","ror":"https://ror.org/0026m8b31","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I4210086830"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaele Canger","raw_affiliation_strings":["Epilepsy Center, S. Paolo Hospital, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Center, S. Paolo Hospital, Milan, Italy","institution_ids":["https://openalex.org/I4210086830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210086830"],"apc_list":{"value":4360,"currency":"USD","value_usd":4360},"apc_paid":null,"fwci":2.1344,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.86306686,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"42","issue":"s1","first_page":"29","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.9190000295639038},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.9980000257492065},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/temporal-lobe-epilepsy","display_name":"temporal lobe epilepsy","score":0.9110000133514404},{"id":"https://openalex.org/keywords/frontal-lobe-epilepsy","display_name":"frontal lobe epilepsy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/idiopathic-generalized-epilepsy","display_name":"idiopathic generalized epilepsy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/focal-epilepsy","display_name":"focal epilepsy","score":0.7129999995231628},{"id":"https://openalex.org/keywords/psychosocial-risk-factors","display_name":"psychosocial risk factors","score":0.7200000286102295},{"id":"https://openalex.org/keywords/seizure-frequency","display_name":"seizure frequency","score":0.6190000176429749},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.9629999995231628},{"id":"https://openalex.org/keywords/social-stigma","display_name":"social stigma","score":0.5820000171661377},{"id":"https://openalex.org/keywords/self-esteem","display_name":"self-esteem","score":0.4650000035762787},{"id":"https://openalex.org/keywords/marital-status","display_name":"marital status","score":0.4350000023841858},{"id":"https://openalex.org/keywords/unemployment","display_name":"unemployment","score":0.7080000042915344},{"id":"https://openalex.org/keywords/family-history-of-depression","display_name":"family history of depression","score":0.6909999847412109},{"id":"https://openalex.org/keywords/age-at-epilepsy-onset","display_name":"age at epilepsy onset","score":0.3779999911785126}],"concepts":[{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.8821431994438171},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.6012954711914062},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.5787160396575928},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5766581296920776},{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.5462299585342407},{"id":"https://openalex.org/C2781099131","wikidata":"https://www.wikidata.org/wiki/Q744385","display_name":"Temporal lobe","level":3,"score":0.5304975509643555},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5050697922706604},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5005526542663574},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.45780134201049805},{"id":"https://openalex.org/C2780874087","wikidata":"https://www.wikidata.org/wiki/Q7447057","display_name":"Seizure types","level":3,"score":0.44396719336509705},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4339505434036255},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3797716498374939},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017034","descriptor_name":"Epilepsy, Frontal Lobe","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D017034","descriptor_name":"Epilepsy, Frontal Lobe","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D017034","descriptor_name":"Epilepsy, Frontal Lobe","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1528-1157.2001.00510.x","doi":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1528-1157.2001.00510.x","pdf_url":null,"source":{"id":"https://openalex.org/S203153751","display_name":"Epilepsia","issn_l":"0013-9580","issn":["0013-9580","1528-1157","1528-1167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"journal-article"},{"id":"pmid:11422352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11422352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W9507477","https://openalex.org/W967607822","https://openalex.org/W1211294399","https://openalex.org/W1607171655","https://openalex.org/W1963970285","https://openalex.org/W1971836248","https://openalex.org/W1972528623","https://openalex.org/W1976973106","https://openalex.org/W1978961123","https://openalex.org/W1979920888","https://openalex.org/W1981614610","https://openalex.org/W1988443427","https://openalex.org/W1994186835","https://openalex.org/W2002886831","https://openalex.org/W2003875510","https://openalex.org/W2009683024","https://openalex.org/W2012498382","https://openalex.org/W2013460998","https://openalex.org/W2015265274","https://openalex.org/W2017304750","https://openalex.org/W2017630402","https://openalex.org/W2018766133","https://openalex.org/W2019114766","https://openalex.org/W2022542197","https://openalex.org/W2026813991","https://openalex.org/W2029092021","https://openalex.org/W2029760159","https://openalex.org/W2031599399","https://openalex.org/W2035481057","https://openalex.org/W2036910921","https://openalex.org/W2037343347","https://openalex.org/W2037383684","https://openalex.org/W2042395094","https://openalex.org/W2044452957","https://openalex.org/W2044572210","https://openalex.org/W2047522333","https://openalex.org/W2051215047","https://openalex.org/W2051542302","https://openalex.org/W2058588621","https://openalex.org/W2058997043","https://openalex.org/W2064171519","https://openalex.org/W2068603628","https://openalex.org/W2081121358","https://openalex.org/W2090080725","https://openalex.org/W2100443579","https://openalex.org/W2103109508","https://openalex.org/W2112096969","https://openalex.org/W2149170641","https://openalex.org/W2152392558","https://openalex.org/W2159797168","https://openalex.org/W2164637156","https://openalex.org/W2170332928","https://openalex.org/W2170692620","https://openalex.org/W2242530628","https://openalex.org/W2290935437","https://openalex.org/W2300893684","https://openalex.org/W2395774743","https://openalex.org/W2405233115","https://openalex.org/W2585405102","https://openalex.org/W3040853039","https://openalex.org/W4255444331","https://openalex.org/W4285719527","https://openalex.org/W4299641216"],"related_works":["https://openalex.org/W2152326266","https://openalex.org/W2404883082","https://openalex.org/W4389439208","https://openalex.org/W1777097182","https://openalex.org/W2056619366","https://openalex.org/W4392455294","https://openalex.org/W2891029863","https://openalex.org/W7084596789","https://openalex.org/W2411404983","https://openalex.org/W2382658787"],"abstract_inverted_index":{"Depression":[0,400],"and":[1,19,46,53,82,85,90,138,181,210,220,236,277,324,334,363,373,376,401,413,456,497,575,590,610,615,634,639,650,672,686,728,759,787,870,872,888,901],"anxiety":[2,402,457,635,673,687,873],"appear":[3],"to":[4,116,186,315,321,390,396,405,479,713,784,815],"be":[5,117,406,480,816,906],"interictal":[6,670],"complications":[7],"in":[8,258,429,447,461,467,568,710,812,822,876,908],"the":[9,24,54,57,104,127,132,153,187,225,253,262,272,278,286,316,327,338,347,369,377,383,397,410,430,462,468,481,494,602,606,611,641,648,655,665,732,879,886,909],"epilepsy":[10,33,39,208,214,317,411,431,464,573,578,626,643,678,695,701],"population.":[11],"Their":[12],"etiology":[13],"is":[14],"multifactorial,":[15],"encompassing":[16],"both":[17,485,885],"neurobiologic":[18,26],"psychosocial":[20,63],"risk":[21],"factors.":[22],"Among":[23],"potential":[25],"determinants,":[27],"special":[28],"interest":[29],"has":[30,826],"focused":[31],"on":[32,224,484,502,508,518,524,533,539,548,554,613,647,899],"variables,":[34],"such":[35],"as":[36,311,313,393,395,592,803],"age":[37,340],"at":[38,152],"onset,":[40],"type":[41,893],"of":[42,49,56,76,80,88,96,101,143,196,202,218,227,252,280,289,298,350,371,385,454,565,586,604,608,620,632,664,736,744,757,840,863,891,894,911],"seizures,":[43,609],"their":[44],"frequency":[45,161,276,288,607],"severity,":[47],"presence":[48],"status":[50],"epilepticus,":[51],"medication,":[52],"laterality":[55],"temporal":[58,206,571,769,780],"lobe":[59,207,213,572,577],"spike":[60],"focus.":[61],"The":[62,216,249,306,452,475,618,790,807],"factors":[64],"include":[65],"mainly":[66],"social":[67],"stigma,":[68],"adverse":[69],"life":[70],"events,":[71],"fear,":[72],"poor":[73],"self-esteem,":[74],"lack":[75],"mastery,":[77],"low":[78],"rate":[79],"marriage":[81],"high":[83],"unemployment,":[84],"a":[86,267,742,751,775,793,819,837,864],"history":[87,743],"personal":[89],"family":[91],"depressive":[92,854],"illness.":[93],"Two":[94,358],"groups":[95,255,273,318],"patients":[97,198,392,569,692,737,761,766,800],"with":[98,199,245,319,570,662,677,693,699,705,720,738,762,767,774,778,782,801,805,818,859],"epilepsy,":[99,201,605],"all":[100,391,798],"whom":[102,203],"attended":[103],"Epilepsy":[105],"Center,":[106],"S.":[107],"Paolo":[108],"Hospital,":[109],"Milan,":[110],"were":[111,123,331,388,458,493,772],"recruited.":[112],"No":[113,164,166,174,182,580,597],"patient":[114,263],"asked":[115],"seen":[118],"for":[119,126,274,368,382,797],"psychiatric":[120],"reasons.":[121],"Patients":[122],"considered":[124],"suitable":[125],"study":[128],"if":[129],"they":[130],"met":[131],"following":[133],"criteria:":[134],"Age":[135],"between":[136,271,409,584,601,867],"18":[137],"50":[139],"years;":[140,145],"An":[141],"education":[142,351],">5":[144],"A":[146],"normal":[147,398],"intelligence":[148,387],"level":[149,349],"[a":[150],"score":[151],"Raven's":[154,378],"Colored":[155],"Progressive":[156,380],"Matrices":[157,381],">17.5":[158],"1];":[159],"Seizure":[160],"<12":[162],"monthly;":[163],"left-handedness;":[165],"other":[167],"drugs,":[168],"apart":[169],"from":[170],"antiepileptic":[171],"drugs":[172],"(AEDs);":[173],"extensive":[175],"cerebral":[176],"lesions":[177,183,771,834],"(for":[178,190],"partial":[179,191,200,463,642,694,707],"epilepsy);":[180],"not":[184],"corresponding":[185],"epileptogenic":[188,587],"area":[189],"epilepsy).":[192],"Group":[193,240],"one":[194,471],"consisted":[195],"150":[197],"106":[204],"had":[205,628,741],"(TLE),":[209],"44,":[211],"frontal":[212,576],"(FLE).":[215,579],"diagnosis":[217],"TLE":[219,476,490,500,516,869],"FLE":[221,531,546],"was":[222,266,309,341,352,582,599],"made":[223],"basis":[226],"anatomo-electroclinical":[228],"criteria":[229],"[anamnestic":[230],"data,":[231],"magnetic":[232],"resonance":[233],"imaging":[234],"(MRI),":[235],"long-term":[237],"video-EEG":[238],"recording].":[239],"two":[241,254,877],"comprised":[242],"70":[243],"subjects":[244],"idiopathic":[246,469,656],"generalized":[247,470,657,700,722],"epilepsy.":[248],"basic":[250],"characteristics":[251],"are":[256,674],"reported":[257,828],"Table":[259],"1.":[260],"In":[261,326],"population,":[264],"there":[265,330],"statistically":[268],"significant":[269,794],"difference":[270,581],"seizure":[275],"number":[279,297,777],"AEDs":[281],"prescribed.":[282],"Mann\u2013Whitney":[283],"procedures":[284],"showed":[285,623,792],"following:":[287],"seizures:":[290],"U":[291,300],"=":[292,301,417,420,424,427,435,438,442,445,506,510,513,522,528,537,543,552,558],"60,":[293],"p":[294,303,449,560],"<":[295,304,450,473,561],"0.05;":[296],"AEDs:":[299],"64.5,":[302],"0.05.":[305,451],"control":[307,328],"group":[308,329,465,477],"matched":[310],"closely":[312],"possible":[314],"respect":[320,783],"sex,":[322],"age,":[323],"education.":[325],"37":[332],"male":[333],"33":[335],"female":[336],"subjects;":[337],"mean":[339,348,416,423,434,441,501,517,532,547],"34.8":[342],"years":[343,354],"(SD,":[344,355],"6.7":[345],"years),":[346],"13.01":[353],"1.09":[356],"years).":[357],"self-rating":[359],"mood":[360,486],"questionnaires":[361,652],"(Zung":[362],"Stai":[364,422,440,616,651],"questionnaires)":[365],"2,":[366],"3":[367],"evaluation":[370],"depression":[372,455,633,671,685,716,811,871],"anxiety,":[374],"respectively,":[375],"Coloured":[379],"assessment":[384],"nonverbal":[386],"administered":[389],"well":[394],"subjects.":[399],"scores":[403],"seemed":[404,712],"significantly":[407],"different":[408,838],"population":[412,627],"controls:":[414],"Zung":[415,433,566,614,649],"54.6":[418],"(SD":[419,426,437,444],"9.04),":[421],"53.9":[425],"8.8)":[428],"sample;":[432],"30.4":[436],"5.03),":[439],"30.08":[443],"4.3)":[446],"controls,":[448,638],"levels":[453,631],"much":[459],"higher":[460,646],"than":[466,636,653,696,717,843],"(p":[472],"0.05).":[474],"appeared":[478,814],"most":[482,495,663],"impaired":[483],"questionnaires,":[487],"especially":[488],"left":[489,530,768,832,868],"patients,":[491],"who":[492],"depressed":[496,758,765,799],"anxious":[498],"(left":[499],"Zung:":[503,519,534,549],"65.3,":[504,511],"SD":[505,512,521,527,536,542,551,557],"4.04,":[507],"Stai:":[509,525,540,555],"3.7;":[514],"right":[515,545,779,844],"56.8,":[520],"2.2,":[523],"56.5,":[526],"1.9;":[529],"52.5,":[535],"3.02,":[538],"51.8,":[541],"3.0;":[544],"52.3,":[550],"2.4,":[553],"52.6,":[556],"2.5;":[559],"0.05)":[562],"(Fig.1).":[563],"Results":[564],"questionnaire":[567],"(TLE)":[574],"found":[583],"lateralization":[585],"focus,":[588],"gender,":[589],"depression/anxiety,":[591],"some":[593],"authors":[594,808],"have":[595],"suggested.":[596],"correlation":[598],"noticed":[600],"duration":[603],"results":[612,619],"questionnaires.":[617],"our":[621,625],"investigation":[622,756,880],"that":[624,640,669,684,734,810,830,904],"more":[629,689,715,883],"elevated":[630],"did":[637,654,718],"sample":[644],"scored":[645],"group.":[658],"These":[659],"findings":[660],"agree":[661],"literature,":[666],"which":[667],"recognized":[668],"frequently":[675],"associated":[676,817],"4-6.":[679],"Several":[680],"studies":[681],"indicated,":[682],"besides,":[683],"occurred":[688],"often":[690],"among":[691,697],"those":[698,719],"7,":[702],"8.":[703],"People":[704],"complex":[706],"seizures":[708,724],"(CPS)":[709],"particular":[711],"report":[714],"primary":[721],"tonic\u2013clonic":[723],"9,":[725],"10.":[726],"Blumer":[727],"Zielinsky":[729],"11":[730],"highlighted":[731],"fact":[733],"62%":[735],"intractable":[739],"CPS":[740],"depression.":[745],"Bromfield":[746],"et":[747],"al.":[748],"12":[749],"performed":[750],"positron":[752],"emission":[753],"tomography":[754],"(PET)":[755],"nondepressed":[760],"CPS.":[763],"Five":[764],"epileptogenetic":[770],"compared":[773,804,858],"similar":[776],"lesions,":[781],"temporal,":[785],"frontal,":[786],"subcortical":[788],"metabolism.":[789,824],"analysis":[791],"inferofrontal":[795,823],"hypometabolism":[796],"CPSs,":[802],"controls.":[806],"concluded":[809],"CPSs":[813],"bilateral":[820,846],"reduction":[821],"It":[825],"been":[827],"13":[829],"unilateral":[831],"hemispheric":[833],"can":[835],"cause":[836],"set":[839],"psychological":[841],"responses":[842],"or":[845],"lesions.":[847],"Moreover,":[848],"intracarotid":[849],"amytal":[850],"injections":[851],"induce":[852],"greater":[853],"reactions":[855],"after":[856],"left-sided":[857],"right-sided":[860],"administration.":[861],"Investigation":[862],"causal":[865],"link":[866],"should":[874,881,897],"proceed":[875],"directions:":[878],"clarify":[882],"precisely":[884],"electrical":[887,900],"chemical":[889,902],"dynamics":[890],"this":[892],"epilepsy;":[895],"it":[896],"center":[898],"correlates":[903],"may":[905],"involved":[907],"genesis":[910],"depression/anxiety":[912],"symptoms.":[913]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}