{"id":"https://openalex.org/W2003174842","doi":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","title":"Effects of serum vitamin\u2010D\u2010binding protein on actin in the presence of plasma gelsolin","display_name":"Effects of serum vitamin\u2010D\u2010binding protein on actin in the presence of plasma gelsolin","publication_year":1986,"publication_date":"1986-10-01","ids":{"openalex":"https://openalex.org/W2003174842","doi":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","mag":"2003174842","pmid":"https://pubmed.ncbi.nlm.nih.gov/3021453"},"language":"en","primary_location":{"id":"doi:10.1111/j.1432-1033.1986.tb09967.x","doi":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1986.tb09967.x","source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1986.tb09967.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110693220","display_name":"Martine Cou\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Martine COU\u00c9","raw_affiliation_strings":["Laboratoire de Biochimie Cellulaire, Colle\u0300ge de France, Paris","Laboratoir\u00e8 de Biochimie Cellulaire, Coll\u00e8ge de France, Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie Cellulaire, Colle\u0300ge de France, Paris","institution_ids":["https://openalex.org/I187986737"]},{"raw_affiliation_string":"Laboratoir\u00e8 de Biochimie Cellulaire, Coll\u00e8ge de France, Paris","institution_ids":["https://openalex.org/I187986737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084455622","display_name":"J. Constans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I3019448017","display_name":"Centre Hospitalier Universitaire de Toulouse","ror":"https://ror.org/017h5q109","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017"]},{"id":"https://openalex.org/I4210138343","display_name":"H\u00f4pital Purpan","ror":"https://ror.org/03vcx3f97","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210138343"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jacques CONSTANS","raw_affiliation_strings":["Centre d'He\u0301motypologie du Centre Nationale de la Recherche Scientifique, Centre Hospitalier Universitaire, Purpan, Toulouse","Centre d'H\u00e9motypologie du Centre Nationale de la Recherche Scientifique, Centre Hospitalier Universitaire, Purpan, Toulouse"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'He\u0301motypologie du Centre Nationale de la Recherche Scientifique, Centre Hospitalier Universitaire, Purpan, Toulouse","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I3019448017","https://openalex.org/I4210138343"]},{"raw_affiliation_string":"Centre d'H\u00e9motypologie du Centre Nationale de la Recherche Scientifique, Centre Hospitalier Universitaire, Purpan, Toulouse","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I3019448017","https://openalex.org/I4210138343"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061918124","display_name":"Anna Olomucki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anna OLOMUCKI","raw_affiliation_strings":["Laboratoire de Biochimie Cellulaire, Colle\u0300ge de France, Paris","Laboratoir\u00e8 de Biochimie Cellulaire, Coll\u00e8ge de France, Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie Cellulaire, Colle\u0300ge de France, Paris","institution_ids":["https://openalex.org/I187986737"]},{"raw_affiliation_string":"Laboratoir\u00e8 de Biochimie Cellulaire, Coll\u00e8ge de France, Paris","institution_ids":["https://openalex.org/I187986737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5110693220"],"corresponding_institution_ids":["https://openalex.org/I187986737"],"apc_list":null,"apc_paid":null,"fwci":0.9185,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.72105952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"160","issue":"2","first_page":"273","last_page":"277"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.6068999767303467,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.6068999767303467,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.1462000012397766,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.07880000025033951,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d-binding-protein","display_name":"vitamin D binding protein","score":0.8840000033378601},{"id":"https://openalex.org/keywords/gelsolin","display_name":"gelsolin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/actin","display_name":"actin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/actin-sequestration","display_name":"actin sequestration","score":0.7129999995231628},{"id":"https://openalex.org/keywords/actin-monomer-binding","display_name":"actin monomer binding","score":0.5059999823570251},{"id":"https://openalex.org/keywords/actin-severing","display_name":"actin filament severing","score":0.5239999890327454},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.7360000014305115},{"id":"https://openalex.org/keywords/calcium-dependence","display_name":"calcium dependence","score":0.421999990940094},{"id":"https://openalex.org/keywords/binding-affinity","display_name":"binding affinity","score":0.3529999852180481}],"concepts":[{"id":"https://openalex.org/C80722340","wikidata":"https://www.wikidata.org/wiki/Q18297560","display_name":"Gelsolin","level":3,"score":0.9948630928993225},{"id":"https://openalex.org/C130861313","wikidata":"https://www.wikidata.org/wiki/Q3775363","display_name":"Actin-binding protein","level":5,"score":0.7345890998840332},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.718999981880188},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6165875792503357},{"id":"https://openalex.org/C153639570","wikidata":"https://www.wikidata.org/wiki/Q906435","display_name":"Vitamin D-binding protein","level":3,"score":0.560245156288147},{"id":"https://openalex.org/C2776190535","wikidata":"https://www.wikidata.org/wiki/Q4676836","display_name":"Actina","level":4,"score":0.4511399567127228},{"id":"https://openalex.org/C2777658833","wikidata":"https://www.wikidata.org/wiki/Q408437","display_name":"EGTA","level":3,"score":0.44807860255241394},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.44559645652770996},{"id":"https://openalex.org/C3620293","wikidata":"https://www.wikidata.org/wiki/Q14908027","display_name":"Actin remodeling","level":5,"score":0.4229673147201538},{"id":"https://openalex.org/C59999672","wikidata":"https://www.wikidata.org/wiki/Q21497084","display_name":"MDia1","level":5,"score":0.4150722622871399},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.376705527305603},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37268537282943726},{"id":"https://openalex.org/C189040839","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Microfilament","level":4,"score":0.3352842926979065},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2690046429634094},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.25202810764312744},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.24895980954170227},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.1435743272304535},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.10536518692970276},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.06922730803489685},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0648740828037262},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002135","descriptor_name":"Calcium-Binding Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008840","descriptor_name":"Microfilament Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013050","descriptor_name":"Spectrometry, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014809","descriptor_name":"Vitamin D-Binding Protein","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D018260","descriptor_name":"Gelsolin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1432-1033.1986.tb09967.x","doi":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1986.tb09967.x","source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:3021453","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3021453","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of biochemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1432-1033.1986.tb09967.x","doi":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1986.tb09967.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1986.tb09967.x","source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2003174842.pdf","grobid_xml":"https://content.openalex.org/works/W2003174842.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1488840584","https://openalex.org/W1494103965","https://openalex.org/W1494497302","https://openalex.org/W1498938399","https://openalex.org/W1501021760","https://openalex.org/W1506245612","https://openalex.org/W1514370510","https://openalex.org/W1535502996","https://openalex.org/W1538692246","https://openalex.org/W1541586041","https://openalex.org/W1543300438","https://openalex.org/W1549704724","https://openalex.org/W1556587164","https://openalex.org/W1562376745","https://openalex.org/W1568637259","https://openalex.org/W1592509174","https://openalex.org/W1670889273","https://openalex.org/W1775749144","https://openalex.org/W1835632918","https://openalex.org/W1911473345","https://openalex.org/W1969049965","https://openalex.org/W1976710138","https://openalex.org/W1991920413","https://openalex.org/W1996151882","https://openalex.org/W2001228992","https://openalex.org/W2008517717","https://openalex.org/W2013066442","https://openalex.org/W2028214469","https://openalex.org/W2034808647","https://openalex.org/W2036623845","https://openalex.org/W2058597230","https://openalex.org/W2069404577","https://openalex.org/W2166659336","https://openalex.org/W4297917728"],"related_works":["https://openalex.org/W1969279937","https://openalex.org/W1997845290","https://openalex.org/W2166659336","https://openalex.org/W2091077599","https://openalex.org/W2151079059","https://openalex.org/W2116426240","https://openalex.org/W1503658815","https://openalex.org/W2024464799","https://openalex.org/W2135037005","https://openalex.org/W1971344738"],"abstract_inverted_index":{"The":[0,107],"interaction":[1],"of":[2,36,70,74,90,105,109,112,123],"serum":[3],"vitamin-D-binding":[4],"protein":[5],"(DBP)":[6],"and":[7,20,48,60,114],"plasma":[8,126],"gelsolin":[9,21,49,113],"with":[10,26,128],"actin":[11,31,75,93,129],"was":[12,58,64],"studied":[13],"using":[14],"fluorescent":[15],"7-chloro-4-nitrobenzo-2-oxa-1,3-diazole-actin":[16],"or":[17,28],"N-pyrenylcarboxyamidomethyl-actin.":[18],"DBP":[19,47,85,98,115],"formed":[22,65],"very":[23],"tight":[24],"complexes":[25],"one":[27,92],"two":[29,125],"monomeric":[30],"subunits":[32],"respectively.":[33],"Kd":[34],"values":[35],"about":[37],"10":[38],"nm":[39],"have":[40],"been":[41],"found":[42],"for":[43],"both":[44],"complexes.":[45],"When":[46],"were":[50],"added":[51],"simultaneously":[52],"to":[53,83],"G-actin":[54],"no":[55,72],"ternary":[56],"complex":[57,63,82],"observed":[59],"the":[61,68,78,88,102],"DBP-actin":[62],"preferentially.":[66],"In":[67],"presence":[69,89],"CaCl2":[71],"transfer":[73],"occurred":[76,130],"from":[77],"1:2":[79],"gelsolin:actin":[80],"molar":[81],"free":[84],"while":[86],"in":[87,131],"EGTA":[91],"monomer":[94],"could":[95],"be":[96],"transferred.":[97],"did":[99],"not":[100],"affect":[101],"severing":[103],"activity":[104],"gelsolin.":[106],"effects":[108],"a":[110],"mixture":[111],"on":[116],"F-actin":[117],"suggest":[118],"that":[119],"only":[120],"individual":[121],"interactions":[122],"these":[124],"proteins":[127],"solution.":[132]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}