{"id":"https://openalex.org/W2003159154","doi":"https://doi.org/10.1016/0928-4680(94)90960-1","title":"Comparative study of different species of oxygen free radicals on the ATP-sensitive potassium channels of the heart","display_name":"Comparative study of different species of oxygen free radicals on the ATP-sensitive potassium channels of the heart","publication_year":1994,"publication_date":"1994-11-01","ids":{"openalex":"https://openalex.org/W2003159154","doi":"https://doi.org/10.1016/0928-4680(94)90960-1","mag":"2003159154"},"language":"en","primary_location":{"id":"doi:10.1016/0928-4680(94)90960-1","doi":"https://doi.org/10.1016/0928-4680(94)90960-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0928-4680(94)90960-1","pdf_url":null,"source":{"id":"https://openalex.org/S14625721","display_name":"Pathophysiology","issn_l":"0928-4680","issn":["0928-4680","1873-149X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathophysiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/0928-4680(94)90960-1","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044932508","display_name":"Koji Tokube","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Tokube","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079095023","display_name":"Tatsuto Kiyosue","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Kiyosue","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073134409","display_name":"Makoto Arita","orcid":"https://orcid.org/0000-0001-9902-0463","observed_orcids":["https://orcid.org/0000-0001-9902-0463","https://orcid.org/0000-0001-6785-3890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Arita","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1400,"currency":"CHF","value_usd":1689},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1689},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":null,"first_page":"473","last_page":"473"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.4584999978542328,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.4584999978542328,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.3375999927520752,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0494999997317791,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxygen-free-radicals","display_name":"oxygen free radicals","score":0.9359999895095825},{"id":"https://openalex.org/keywords/atp-sensitive-potassium-channels","display_name":"ATP-sensitive potassium channels","score":0.8849999904632568},{"id":"https://openalex.org/keywords/cardiac-potassium-channels","display_name":"cardiac potassium channels","score":0.7250000238418579},{"id":"https://openalex.org/keywords/vasoactive-intestinal-peptide","display_name":"vasoactive intestinal peptide","score":0.9459999799728394},{"id":"https://openalex.org/keywords/catecholamine-release","display_name":"catecholamine release","score":0.9940000176429749},{"id":"https://openalex.org/keywords/adrenal-medulla","display_name":"adrenal medulla","score":0.9359999895095825},{"id":"https://openalex.org/keywords/muscarinic-stimulation","display_name":"muscarinic stimulation","score":0.6769999861717224},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.8970000147819519}],"concepts":[{"id":"https://openalex.org/C2780841807","wikidata":"https://www.wikidata.org/wiki/Q407952","display_name":"Muscarine","level":4,"score":0.9611678719520569},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.7803727984428406},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6479698419570923},{"id":"https://openalex.org/C8330315","wikidata":"https://www.wikidata.org/wiki/Q414964","display_name":"Vasoactive intestinal peptide","level":4,"score":0.6181638240814209},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5767456889152527},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5544376969337463},{"id":"https://openalex.org/C2779014961","wikidata":"https://www.wikidata.org/wiki/Q415168","display_name":"Ionophore","level":3,"score":0.5022499561309814},{"id":"https://openalex.org/C2775894120","wikidata":"https://www.wikidata.org/wiki/Q271663","display_name":"Catecholamine","level":2,"score":0.4537979066371918},{"id":"https://openalex.org/C2777597313","wikidata":"https://www.wikidata.org/wiki/Q934888","display_name":"Adrenal medulla","level":3,"score":0.4413917660713196},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.3002822995185852},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2271636426448822},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18938180804252625},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.08339038491249084},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0746569037437439},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06746679544448853},{"id":"https://openalex.org/C33789571","wikidata":"https://www.wikidata.org/wiki/Q410959","display_name":"Muscarinic acetylcholine receptor","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/0928-4680(94)90960-1","doi":"https://doi.org/10.1016/0928-4680(94)90960-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0928-4680(94)90960-1","pdf_url":null,"source":{"id":"https://openalex.org/S14625721","display_name":"Pathophysiology","issn_l":"0928-4680","issn":["0928-4680","1873-149X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathophysiology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/0928-4680(94)90960-1","doi":"https://doi.org/10.1016/0928-4680(94)90960-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0928-4680(94)90960-1","pdf_url":null,"source":{"id":"https://openalex.org/S14625721","display_name":"Pathophysiology","issn_l":"0928-4680","issn":["0928-4680","1873-149X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathophysiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2066780235","https://openalex.org/W2038730237","https://openalex.org/W1984140970","https://openalex.org/W2400112611","https://openalex.org/W2011807029","https://openalex.org/W1608029426","https://openalex.org/W7100856492","https://openalex.org/W2162360018","https://openalex.org/W2209398912","https://openalex.org/W4484219"],"abstract_inverted_index":{"The":[0,63],"effects":[1],"of":[2,29,39,66,77],"vasoactive":[3],"intestinal":[4],"polypeptide":[5],"(VIP)":[6],"on":[7,68],"catecholamine":[8],"(CA)":[9],"secretion":[10,28,71],"by":[11],"isolated":[12],"guinea":[13],"pig":[14],"adrenal":[15],"medullary":[16],"cells":[17],"were":[18],"studied.":[19],"VIP":[20,67],"(1":[21],"\u03bcM)":[22],"alone":[23],"induced":[24],"only":[25],"a":[26],"slight":[27],"CA,":[30],"but":[31,47],"it":[32,42],"stimulated":[33,43],"ACh-induced":[34],"CA":[35,45,50,61,70],"secretion.":[36,51,62],"At":[37],"concentrations":[38,76],"0.01\u20131":[40],"\u03bcM,":[41],"muscarine-induced":[44,69],"secretion,":[46],"not":[48,54],"nicotine-induced":[49],"It":[52],"did":[53],"affect":[55],"high":[56],"K+":[57],"or":[58],"Ca2+":[59],"ionophore-induced":[60],"stimulatory":[64],"effect":[65],"was":[72,81],"observed":[73],"at":[74],"muscarine":[75],"2\u2013200":[78],"\u03bcM":[79],"and":[80],"detectable":[82],"after":[83],"2":[84],"min":[85],"incubation.":[86]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}