{"id":"https://openalex.org/W2003047480","doi":"https://doi.org/10.1016/s0165-3806(97)00022-9","title":"Calbindin-D28k is regulated by adrenal steroids in hypothalamic tissue during prenatal development","display_name":"Calbindin-D28k is regulated by adrenal steroids in hypothalamic tissue during prenatal development","publication_year":1997,"publication_date":"1997-05-01","ids":{"openalex":"https://openalex.org/W2003047480","doi":"https://doi.org/10.1016/s0165-3806(97)00022-9","mag":"2003047480","pmid":"https://pubmed.ncbi.nlm.nih.gov/9174253"},"language":"en","primary_location":{"id":"doi:10.1016/s0165-3806(97)00022-9","doi":"https://doi.org/10.1016/s0165-3806(97)00022-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0165-3806(97)00022-9","pdf_url":null,"source":{"id":"https://openalex.org/S20757867","display_name":"Developmental Brain Research","issn_l":"0165-3806","issn":["0165-3806","1872-6755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031905494","display_name":"Edwin D. Lephart","orcid":"https://orcid.org/0000-0003-2027-9187","observed_orcids":["https://orcid.org/0000-0003-2027-9187"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Edwin D Lephart","raw_affiliation_strings":["Department of Zoology, Brigham Young University, Provo, UT 84062, USA. edlephar@acd1.byu.edu","Department of Zoology, Brigham Young University, Provo, UT 84062, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Brigham Young University, Provo, UT 84062, USA. edlephar@acd1.byu.edu","institution_ids":["https://openalex.org/I100005738"]},{"raw_affiliation_string":"Department of Zoology, Brigham Young University, Provo, UT 84062, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069799725","display_name":"Melanie A. Watson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melanie A Watson","raw_affiliation_strings":["Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083144379","display_name":"Nathan A. Jacobson","orcid":"https://orcid.org/0000-0001-7260-2084","observed_orcids":["https://orcid.org/0000-0001-7260-2084"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan A Jacobson","raw_affiliation_strings":["Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049488970","display_name":"Reuben W. Rhees","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reuben W Rhees","raw_affiliation_strings":["Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058094660","display_name":"David R. Ladle","orcid":"https://orcid.org/0000-0001-8447-899X","observed_orcids":["https://orcid.org/0000-0001-8447-899X"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David R Ladle","raw_affiliation_strings":["Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, Cellular Biology Division, Brigham Young University, Provo, UT 84062, USA","institution_ids":["https://openalex.org/I100005738"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031905494"],"corresponding_institution_ids":["https://openalex.org/I100005738"],"apc_list":null,"apc_paid":null,"fwci":1.7041,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.8289354,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"100","issue":"1","first_page":"117","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.7167999744415283,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.7167999744415283,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.1445000022649765,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.023099999874830246,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calbindin-d28k","display_name":"calbindin-D28k","score":0.9990000128746033},{"id":"https://openalex.org/keywords/medial-basal-hypothalamus","display_name":"medial basal hypothalamus","score":0.8569999933242798},{"id":"https://openalex.org/keywords/adrenal-steroids","display_name":"adrenal steroids","score":0.6840000152587891},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.9760000109672546},{"id":"https://openalex.org/keywords/prenatal-development","display_name":"prenatal development","score":0.9020000100135803},{"id":"https://openalex.org/keywords/fetal-brain","display_name":"fetal brain","score":0.5450000166893005},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7279999852180481},{"id":"https://openalex.org/keywords/prenatal-stress","display_name":"prenatal stress","score":0.9359999895095825},{"id":"https://openalex.org/keywords/adrenalectomy","display_name":"adrenalectomy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hypothalamic-gene-expression","display_name":"hypothalamic gene expression","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.7500110268592834},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7230717539787292},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6652504205703735},{"id":"https://openalex.org/C63405245","wikidata":"https://www.wikidata.org/wiki/Q9076644","display_name":"Sexual differentiation","level":3,"score":0.6407368183135986},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6354747414588928},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.6343785524368286},{"id":"https://openalex.org/C2776847746","wikidata":"https://www.wikidata.org/wiki/Q2297155","display_name":"Prenatal development","level":4,"score":0.5048399567604065},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.4489195644855499},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.4342684745788574},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.39752012491226196},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.36775755882263184},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10771328210830688},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0970526933670044},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000315","descriptor_name":"Adrenalectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005314","descriptor_name":"Embryonic and Fetal Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007033","descriptor_name":"Hypothalamus, Middle","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D007033","descriptor_name":"Hypothalamus, Middle","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012149","descriptor_name":"Restraint, Physical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064026","descriptor_name":"Calbindins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064030","descriptor_name":"S100 Calcium Binding Protein G","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D064092","descriptor_name":"Calbindin 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0165-3806(97)00022-9","doi":"https://doi.org/10.1016/s0165-3806(97)00022-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0165-3806(97)00022-9","pdf_url":null,"source":{"id":"https://openalex.org/S20757867","display_name":"Developmental Brain Research","issn_l":"0165-3806","issn":["0165-3806","1872-6755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Brain Research","raw_type":"journal-article"},{"id":"pmid:9174253","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9174253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research. Developmental brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1554931552","https://openalex.org/W1775749144","https://openalex.org/W1963951882","https://openalex.org/W1989867248","https://openalex.org/W1991348046","https://openalex.org/W1992227820","https://openalex.org/W2007130804","https://openalex.org/W2013519751","https://openalex.org/W2018488491","https://openalex.org/W2036644342","https://openalex.org/W2042549272","https://openalex.org/W2044885060","https://openalex.org/W2068629598","https://openalex.org/W2072306328","https://openalex.org/W2078397006","https://openalex.org/W2111516838","https://openalex.org/W2156625231"],"related_works":["https://openalex.org/W2078397006","https://openalex.org/W2017278451","https://openalex.org/W7045267262","https://openalex.org/W4234241094","https://openalex.org/W2068573264","https://openalex.org/W2016995400","https://openalex.org/W2054951638","https://openalex.org/W2005192333","https://openalex.org/W2027820338","https://openalex.org/W1951315244"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}