{"id":"https://openalex.org/W2003013739","doi":"https://doi.org/10.1016/0092-8674(82)90315-4","title":"The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels","display_name":"The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels","publication_year":1982,"publication_date":"1982-12-01","ids":{"openalex":"https://openalex.org/W2003013739","doi":"https://doi.org/10.1016/0092-8674(82)90315-4","mag":"2003013739","pmid":"https://pubmed.ncbi.nlm.nih.gov/7159929"},"language":"en","primary_location":{"id":"doi:10.1016/0092-8674(82)90315-4","doi":"https://doi.org/10.1016/0092-8674(82)90315-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0092-8674(82)90315-4","pdf_url":null,"source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2003013739"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032120960","display_name":"Beth DiDomenico","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beth J. Didomenico","raw_affiliation_strings":["University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076607968","display_name":"G Bugaisky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabrielle E. Bugaisky","raw_affiliation_strings":["University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108509230","display_name":"Susan Lee Lindquist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Lindquist","raw_affiliation_strings":["University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chicago Department of Biology 1103 E. 57th Street Chicago, Illinois 60637 USA","institution_ids":["https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I40347166"],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":9.3692,"has_fulltext":false,"cited_by_count":521,"citation_normalized_percentile":{"value":0.99048233,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"31","issue":"3","first_page":"593","last_page":"603"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-shock-response","display_name":"heat shock response","score":0.9869999885559082},{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":0.9100000262260437},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.878000020980835},{"id":"https://openalex.org/keywords/transcriptional-repression","display_name":"transcriptional repression","score":0.7149999737739563},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.9160000085830688},{"id":"https://openalex.org/keywords/mrna-stability","display_name":"mRNA stability","score":0.8109999895095825},{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila","score":0.6309999823570251},{"id":"https://openalex.org/keywords/temperature-stress","display_name":"temperature stress","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8341083526611328},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.8099457025527954},{"id":"https://openalex.org/C186310378","wikidata":"https://www.wikidata.org/wiki/Q941796","display_name":"Psychological repression","level":4,"score":0.6996299028396606},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.6674178242683411},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.6660752296447754},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.6276140213012695},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.564886212348938},{"id":"https://openalex.org/C137984847","wikidata":"https://www.wikidata.org/wiki/Q1621258","display_name":"Heat shock","level":4,"score":0.5121481418609619},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4130639433860779},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.33267301321029663},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3161447048187256},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2759570777416229},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0092-8674(82)90315-4","doi":"https://doi.org/10.1016/0092-8674(82)90315-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0092-8674(82)90315-4","pdf_url":null,"source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},{"id":"pmid:7159929","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7159929","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1530814774","https://openalex.org/W1589329776","https://openalex.org/W1601298028","https://openalex.org/W1606423922","https://openalex.org/W1645759506","https://openalex.org/W1865160862","https://openalex.org/W1913296786","https://openalex.org/W1967847292","https://openalex.org/W1968209090","https://openalex.org/W1977904435","https://openalex.org/W1978640160","https://openalex.org/W1981256745","https://openalex.org/W1992151737","https://openalex.org/W1999382048","https://openalex.org/W2010021658","https://openalex.org/W2011361638","https://openalex.org/W2011607607","https://openalex.org/W2011836510","https://openalex.org/W2014040442","https://openalex.org/W2015232640","https://openalex.org/W2021733632","https://openalex.org/W2021866483","https://openalex.org/W2022233771","https://openalex.org/W2025675183","https://openalex.org/W2029136629","https://openalex.org/W2034297812","https://openalex.org/W2038292415","https://openalex.org/W2039188025","https://openalex.org/W2042543706","https://openalex.org/W2046124432","https://openalex.org/W2055124007","https://openalex.org/W2064403333","https://openalex.org/W2069030183","https://openalex.org/W2076300996","https://openalex.org/W2077077811","https://openalex.org/W2079729858","https://openalex.org/W2080907649","https://openalex.org/W2081938019","https://openalex.org/W2084627466","https://openalex.org/W2086412670","https://openalex.org/W2087922243","https://openalex.org/W2095258008","https://openalex.org/W2098749939","https://openalex.org/W2099964650","https://openalex.org/W2100837269","https://openalex.org/W2122071347","https://openalex.org/W2169408823","https://openalex.org/W2503157622","https://openalex.org/W2935601413","https://openalex.org/W4240437334","https://openalex.org/W6671079212","https://openalex.org/W6672530691","https://openalex.org/W7095995388"],"related_works":["https://openalex.org/W2074699940","https://openalex.org/W2111184928","https://openalex.org/W2274080261","https://openalex.org/W2035673447","https://openalex.org/W1561849216","https://openalex.org/W2007659390","https://openalex.org/W1790425926","https://openalex.org/W2069030183","https://openalex.org/W2019736273","https://openalex.org/W4236277918"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}