{"id":"https://openalex.org/W2002844147","doi":"https://doi.org/10.1097/01.brs.0000083235.74593.49","title":"Allelic Variants of Human Melatonin 1A Receptor in Patients with Familial Adolescent Idiopathic Scoliosis","display_name":"Allelic Variants of Human Melatonin 1A Receptor in Patients with Familial Adolescent Idiopathic Scoliosis","publication_year":2003,"publication_date":"2003-08-27","ids":{"openalex":"https://openalex.org/W2002844147","doi":"https://doi.org/10.1097/01.brs.0000083235.74593.49","mag":"2002844147","pmid":"https://pubmed.ncbi.nlm.nih.gov/12973153"},"language":"en","primary_location":{"id":"doi:10.1097/01.brs.0000083235.74593.49","doi":"https://doi.org/10.1097/01.brs.0000083235.74593.49","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.brs.0000083235.74593.49","pdf_url":null,"source":{"id":"https://openalex.org/S4026894","display_name":"Spine","issn_l":"0362-2436","issn":["0362-2436","1528-1159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071271125","display_name":"Jose Antonio Morcuende","orcid":"https://orcid.org/0000-0002-0688-085X","observed_orcids":["https://orcid.org/0000-0002-0688-085X"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]},{"id":"https://openalex.org/I2802216851","display_name":"University of Iowa Hospitals and Clinics","ror":"https://ror.org/04g2swc55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126307644","https://openalex.org/I2802216851","https://openalex.org/I4210142782"]},{"id":"https://openalex.org/I4210142782","display_name":"University of Iowa Health Care","ror":"https://ror.org/0431j1t39","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126307644","https://openalex.org/I4210142782"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jose A. Morcuende","raw_affiliation_strings":["Department of Orthopaedic Surgery, University of Iowa, Iowa City, Iowa, USA. jose-morcuende@uiowa.edu","Address reprint requests to Jose A. Morcuende, MD, PhD, Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, IA City, IA 52242. E-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, University of Iowa, Iowa City, Iowa, USA. jose-morcuende@uiowa.edu","institution_ids":["https://openalex.org/I126307644","https://openalex.org/I4210142782"]},{"raw_affiliation_string":"Address reprint requests to Jose A. Morcuende, MD, PhD, Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, IA City, IA 52242. E-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I2802216851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006169412","display_name":"Raman Minhas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raman Minhas","raw_affiliation_strings":["Pediatrics, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, and","institution_ids":["https://openalex.org/I4210147155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003993102","display_name":"Lori A. Dolan","orcid":"https://orcid.org/0000-0003-2455-2187","observed_orcids":["https://orcid.org/0000-0003-2455-2187"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Lori Dolan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jeff Stevens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jeff Stevens","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043534522","display_name":"John S. Beck","orcid":"https://orcid.org/0000-0003-4063-4422","observed_orcids":["https://orcid.org/0000-0003-4063-4422","https://orcid.org/0000-0001-7799-3416"]},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Beck","raw_affiliation_strings":["Pediatrics, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, and","institution_ids":["https://openalex.org/I4210147155"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kai Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kai Wang","raw_affiliation_strings":["Biostatistics, University of Iowa, Iowa City, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics, University of Iowa, Iowa City, Iowa, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105513431","display_name":"Stuart L. Weinstein","orcid":"https://orcid.org/0000-0002-3676-6687","observed_orcids":["https://orcid.org/0000-0002-3676-6687"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Stuart L. Weinstein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5048989892","display_name":"Val C. Sheffield","orcid":"https://orcid.org/0000-0002-6282-0835","observed_orcids":["https://orcid.org/0000-0002-6282-0835"]},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Val Sheffield","raw_affiliation_strings":["Pediatrics, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, and","institution_ids":["https://openalex.org/I4210147155"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5003993102","https://openalex.org/A5071271125","https://openalex.org/A5105513431"],"corresponding_institution_ids":["https://openalex.org/I126307644","https://openalex.org/I2802216851","https://openalex.org/I4210142782"],"apc_list":null,"apc_paid":null,"fwci":1.5279,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.82368966,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"28","issue":"17","first_page":"2025","last_page":"2028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11030","display_name":"Scoliosis diagnosis and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11030","display_name":"Scoliosis diagnosis and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12830","display_name":"Pectus Deformity Diagnosis and Treatment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adolescent-idiopathic-scoliosis","display_name":"adolescent idiopathic scoliosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.9480000138282776},{"id":"https://openalex.org/keywords/allelic-variants","display_name":"allelic variants","score":0.753000020980835},{"id":"https://openalex.org/keywords/single-strand-conformation-polymorphism","display_name":"single-strand conformation polymorphism","score":0.8140000104904175},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6110000014305115},{"id":"https://openalex.org/keywords/melatonin-metabolism","display_name":"melatonin metabolism","score":0.8339999914169312}],"concepts":[{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6640037298202515},{"id":"https://openalex.org/C142870003","wikidata":"https://www.wikidata.org/wiki/Q843863","display_name":"Genetic linkage","level":3,"score":0.5366228818893433},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.4930536448955536},{"id":"https://openalex.org/C2781269140","wikidata":"https://www.wikidata.org/wiki/Q24784310","display_name":"Melatonin receptor","level":3,"score":0.444460928440094},{"id":"https://openalex.org/C2780955175","wikidata":"https://www.wikidata.org/wiki/Q174857","display_name":"Scoliosis","level":2,"score":0.4415627121925354},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.436148464679718},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4218190610408783},{"id":"https://openalex.org/C188997412","wikidata":"https://www.wikidata.org/wiki/Q1640386","display_name":"Proband","level":4,"score":0.4139326214790344},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3713650405406952},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.28416866064071655},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2561703324317932},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21799927949905396},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1277177631855011},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002894","descriptor_name":"Chromosomes, Human, Pair 4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005192","descriptor_name":"Family Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008126","descriptor_name":"Lod Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012600","descriptor_name":"Scoliosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012600","descriptor_name":"Scoliosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018807","descriptor_name":"Polymorphism, Single-Stranded Conformational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044094","descriptor_name":"Receptors, Melatonin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.brs.0000083235.74593.49","doi":"https://doi.org/10.1097/01.brs.0000083235.74593.49","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.brs.0000083235.74593.49","pdf_url":null,"source":{"id":"https://openalex.org/S4026894","display_name":"Spine","issn_l":"0362-2436","issn":["0362-2436","1528-1159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"journal-article"},{"id":"pmid:12973153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12973153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1557411044","https://openalex.org/W1961032822","https://openalex.org/W1972595560","https://openalex.org/W1977673703","https://openalex.org/W1982316662","https://openalex.org/W1987178992","https://openalex.org/W1989120103","https://openalex.org/W1990762151","https://openalex.org/W1990810827","https://openalex.org/W2001277182","https://openalex.org/W2005565257","https://openalex.org/W2006672681","https://openalex.org/W2011870605","https://openalex.org/W2029656462","https://openalex.org/W2034348289","https://openalex.org/W2038012997","https://openalex.org/W2039252843","https://openalex.org/W2041820882","https://openalex.org/W2045483209","https://openalex.org/W2063537184","https://openalex.org/W2069558876","https://openalex.org/W2072926504","https://openalex.org/W2078367316","https://openalex.org/W2107871825","https://openalex.org/W2134387380","https://openalex.org/W2154134138","https://openalex.org/W2178541010","https://openalex.org/W2254969012","https://openalex.org/W2315718042","https://openalex.org/W2397582134","https://openalex.org/W2399812860","https://openalex.org/W2400842345","https://openalex.org/W2986923534","https://openalex.org/W3143745742","https://openalex.org/W4250042194","https://openalex.org/W4254494674","https://openalex.org/W4293879092"],"related_works":["https://openalex.org/W2033506321","https://openalex.org/W2043651315","https://openalex.org/W2057010715","https://openalex.org/W2073209193","https://openalex.org/W238157698","https://openalex.org/W2340832640","https://openalex.org/W2791927813","https://openalex.org/W2072789550","https://openalex.org/W7120412113","https://openalex.org/W3029171493"],"abstract_inverted_index":{"STUDY":[0],"DESIGN:":[1],"A":[2],"genetic":[3,81,248,258],"study":[4,17,232,288],"of":[5,15,74,93,168,286,292,304,313,342],"patients":[6],"with":[7,164],"familial":[8],"adolescent":[9,65,94,111,280,345],"idiopathic":[10,46,66,95,112,141,281,346],"scoliosis.":[11,282,347],"OBJECTIVES:":[12],"The":[13,62,187,284,311],"purpose":[14],"this":[16,231,287],"was":[18,154,162,193,222,270],"to":[19,117,130,294,332],"evaluate":[20],"the":[21,33,49,75,124,181,198,251,277,301,305,316,327,330,340],"evidence":[22,90,109,224,291],"for":[23,36,91,156,183,189,195,225,250,253,279,307,325,338],"linkage":[24,92,226,293],"on":[25,133],"chromosome":[26,100,134,169,228,295],"4q":[27,170,229,296],"and":[28,123,147,176,217,243,265,268,276,297,337],"determine":[29],"whether":[30],"mutations":[31,196,299],"in":[32,71,120,197,230,262,300,315,329,344],"gene":[34,188,252,274,306,328],"coding":[35,199,302],"melatonin":[37,121,185,191,255,309,318,343],"receptor":[38,127,192,319],"are":[39],"present.":[40],"SUMMARY":[41],"OF":[42],"BACKGROUND":[43],"DATA:":[44],"Adolescent":[45],"scoliosis":[47,67,96,113,142],"is":[48,68,107,128],"most":[50],"common":[51],"spine":[52],"deformity":[53],"arising":[54],"during":[55],"childhood,":[56],"but":[57],"its":[58],"cause":[59],"remains":[60],"unknown.":[61],"fact":[63],"that":[64,110],"often":[69],"seen":[70],"several":[72,98],"members":[73],"same":[76],"family":[77],"strongly":[78],"suggests":[79],"a":[80,118,157,212,322],"factor.":[82],"Recent":[83],"work":[84],"by":[85,205],"Wise":[86],"et":[87],"al":[88],"provides":[89],"at":[97,172,227],"different":[99],"sites,":[101],"including":[102],"4q.":[103,135],"In":[104],"addition,":[105],"there":[106,269],"some":[108],"may":[114],"be":[115,131],"related":[116],"disturbance":[119],"metabolism,":[122],"human":[125,184,190,254,308,317],"melatonin-1A":[126],"known":[129],"located":[132],"METHODS:":[136],"Probands":[137],"having":[138],"clinically":[139],"relevant":[140],"(Cobb":[143],"angle":[144],">30":[145],"degrees)":[146],"their":[148],"relatives":[149],"were":[150,215,260],"identified.":[151],"Radiographic":[152],"confirmation":[153],"required":[155],"positive":[158],"diagnosis.":[159],"Linkage":[160],"analysis":[161],"performed":[163],"15":[165],"microsatellite":[166,178],"markers":[167,179],"spaced":[171],"approximately":[173],"10-cM":[174],"resolution":[175],"5":[177],"surrounding":[180],"site":[182],"receptor.":[186,256,310],"screened":[194],"region":[200,303],"using":[201],"genomic":[202],"DNA":[203],"samples":[204],"single-strand":[206,238],"conformational":[207],"polymorphism":[208,240],"analysis.":[209],"Amplimers":[210],"showing":[211],"band":[213,241],"shift":[214],"reamplified":[216],"sequenced":[218],"bidirectionally.":[219],"RESULTS:":[220],"There":[221],"no":[223,271,290,298],"population.":[233],"Twenty-nine":[234],"individuals":[235],"demonstrated":[236,246,289],"aberrant":[237],"conformation":[239],"patterns,":[242],"sequence":[244],"evaluation":[245],"six":[247],"polymorphisms":[249],"These":[257],"variations":[259],"found":[261],"both":[263],"affected":[264],"nonaffected":[266],"individuals,":[267],"correlation":[272],"between":[273],"variants":[275,314],"phenotype":[278],"CONCLUSIONS:":[283],"results":[285],"identification":[312],"could":[320],"provide":[321],"useful":[323],"tool":[324],"testing":[326],"predisposition":[331],"various":[333],"other":[334],"melatonin-related":[335],"disorders":[336],"clarifying":[339],"role":[341]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}