{"id":"https://openalex.org/W2002258016","doi":"https://doi.org/10.1249/mss.0000000000000405","title":"Mesenchymal Stem Cells Augment the Adaptive Response to Eccentric Exercise","display_name":"Mesenchymal Stem Cells Augment the Adaptive Response to Eccentric Exercise","publication_year":2014,"publication_date":"2014-06-06","ids":{"openalex":"https://openalex.org/W2002258016","doi":"https://doi.org/10.1249/mss.0000000000000405","mag":"2002258016","pmid":"https://pubmed.ncbi.nlm.nih.gov/24905768"},"language":"en","primary_location":{"id":"doi:10.1249/mss.0000000000000405","doi":"https://doi.org/10.1249/mss.0000000000000405","is_oa":false,"landing_page_url":"https://doi.org/10.1249/mss.0000000000000405","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040037697","display_name":"Kai Zou","orcid":"https://orcid.org/0000-0003-4164-7129","observed_orcids":["https://orcid.org/0000-0003-4164-7129"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I2801919071","display_name":"University of Illinois System","ror":"https://ror.org/05e94g991","country_code":"US","type":"education","lineage":["https://openalex.org/I2801919071"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"KAI ZOU","raw_affiliation_strings":["1Department of Kinesiology and Community Health, University of Illinois, Urbana, IL; 2Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and 3Division of Biomedical Sciences, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Kinesiology and Community Health, University of Illinois, Urbana, IL; 2Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and 3Division of Biomedical Sciences, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I2801919071"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017481308","display_name":"Heather D. Huntsman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"HEATHER D. HUNTSMAN","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109113168","display_name":"CARMEN M. VALERO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"CARMEN M. VALERO","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047315755","display_name":"Joseph T. Adams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JOSEPH ADAMS","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038917321","display_name":"Jack T. Skelton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jack SKELTON","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050635195","display_name":"Michael De Lisio","orcid":"https://orcid.org/0000-0002-6462-2955","observed_orcids":["https://orcid.org/0000-0002-6462-2955"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MICHAEL DE LISIO","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041304476","display_name":"Tor Jensen","orcid":"https://orcid.org/0000-0001-7606-8421","observed_orcids":["https://orcid.org/0000-0001-7606-8421"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I2801919071","display_name":"University of Illinois System","ror":"https://ror.org/05e94g991","country_code":"US","type":"education","lineage":["https://openalex.org/I2801919071"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tor JENSEN","raw_affiliation_strings":["Division of Biomedical Sciences, University of Illinois, Urbana, IL","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Division of Biomedical Sciences, University of Illinois, Urbana, IL</em>"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biomedical Sciences, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I2801919071"]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Division of Biomedical Sciences, University of Illinois, Urbana, IL</em>","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I2801919071"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051614460","display_name":"Marni D. Boppart","orcid":"https://orcid.org/0000-0003-0369-6974","observed_orcids":["https://orcid.org/0000-0003-0369-6974"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MARNI D. BOPPART","raw_affiliation_strings":["Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","</em>","<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana, IL; and","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"</em>","institution_ids":[]},{"raw_affiliation_string":"<em xmlns:mrws=\"http://webservices.ovid.com/mrws/1.0\">Department of Kinesiology and Community Health, University of Illinois, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6393,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.8260933,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"47","issue":"2","first_page":"315","last_page":"325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/eccentric-exercise","display_name":"eccentric exercise","score":0.7670000195503235},{"id":"https://openalex.org/keywords/skeletal-muscle-adaptation","display_name":"skeletal muscle adaptation","score":0.6389999985694885},{"id":"https://openalex.org/keywords/alpha7beta1-integrin","display_name":"alpha7beta1 integrin","score":0.8820000290870667},{"id":"https://openalex.org/keywords/satellite-cells","display_name":"satellite cells","score":0.902999997138977},{"id":"https://openalex.org/keywords/pax7","display_name":"Pax7","score":0.9229999780654907},{"id":"https://openalex.org/keywords/muscle-fiber-size","display_name":"muscle fiber size","score":0.550000011920929},{"id":"https://openalex.org/keywords/stem-cell-transplantation","display_name":"stem cell transplantation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.5230000019073486},{"id":"https://openalex.org/keywords/muscle-growth","display_name":"muscle growth","score":0.3440000116825104},{"id":"https://openalex.org/keywords/handgrip-strength","display_name":"grip strength","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.697955846786499},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.5813016891479492},{"id":"https://openalex.org/C126707884","wikidata":"https://www.wikidata.org/wiki/Q305876","display_name":"sed","level":2,"score":0.5339217185974121},{"id":"https://openalex.org/C100784341","wikidata":"https://www.wikidata.org/wiki/Q1340491","display_name":"Eccentric","level":2,"score":0.4924369752407074},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.44300568103790283},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.43982207775115967},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4350696802139282},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4256686568260193},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4049977660179138},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3859831690788269},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3547290563583374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2858814001083374},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2795161008834839},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2765403687953949},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20286357402801514},{"id":"https://openalex.org/C2775944032","wikidata":"https://www.wikidata.org/wiki/Q22907659","display_name":"Patient satisfaction","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000950","descriptor_name":"Antigens, Ly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017493","descriptor_name":"Leukocyte Common Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D045164","descriptor_name":"Mesenchymal Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053580","descriptor_name":"Muscle Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1249/mss.0000000000000405","doi":"https://doi.org/10.1249/mss.0000000000000405","is_oa":false,"landing_page_url":"https://doi.org/10.1249/mss.0000000000000405","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},{"id":"pmid:24905768","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24905768","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine and science in sports and exercise","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1964817674","https://openalex.org/W1966786218","https://openalex.org/W1983191999","https://openalex.org/W1983510492","https://openalex.org/W1991248271","https://openalex.org/W1999902156","https://openalex.org/W2010253303","https://openalex.org/W2030897641","https://openalex.org/W2043818547","https://openalex.org/W2053453409","https://openalex.org/W2055917728","https://openalex.org/W2056883423","https://openalex.org/W2057868246","https://openalex.org/W2063515332","https://openalex.org/W2072784433","https://openalex.org/W2076491580","https://openalex.org/W2081679895","https://openalex.org/W2082330618","https://openalex.org/W2084091316","https://openalex.org/W2088883625","https://openalex.org/W2091545998","https://openalex.org/W2104144179","https://openalex.org/W2104821101","https://openalex.org/W2117479856","https://openalex.org/W2117789591","https://openalex.org/W2124672774","https://openalex.org/W2132371677","https://openalex.org/W2136145695","https://openalex.org/W2137658965","https://openalex.org/W2141399230","https://openalex.org/W2148950581","https://openalex.org/W2162769724","https://openalex.org/W2171507288"],"related_works":["https://openalex.org/W2055917728","https://openalex.org/W2029167258","https://openalex.org/W2319660964","https://openalex.org/W2734978951","https://openalex.org/W2104821101","https://openalex.org/W2321289588","https://openalex.org/W2016383197","https://openalex.org/W2318852041","https://openalex.org/W3041786407","https://openalex.org/W3175133006"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1,80,236],"\u03b17\u03b21":[2],"integrin":[3,34],"is":[4],"a":[5,145],"transmembrane":[6],"protein":[7],"expressed":[8],"in":[9,35,69,73,100,212,230,248,254,265],"the":[10,16,20,32,36,74,89,95,163,231,266,273],"skeletal":[11,37,102],"muscle":[12,38,71,103,256,267],"that":[13,28,242,262],"can":[14],"link":[15],"actin":[17],"cytoskeleton":[18],"to":[19,49,87,91,137,245,276],"surrounding":[21],"basal":[22],"lamina.":[23],"We":[24],"have":[25],"previously":[26],"demonstrated":[27],"transgenic":[29],"mice":[30,130],"overexpressing":[31],"\u03b17B":[33],"(MCK:\u03b17B;":[39],"\u03b17Tg)":[40],"mount":[41],"an":[42],"enhanced":[43,180],"satellite":[44,182,249],"cell":[45,183,250],"and":[46,77,115,185,207,217,252],"growth":[47,229,253],"response":[48,275],"single":[50],"or":[51,128,134,153,228],"multiple":[52],"bouts":[53],"of":[54,126,166,201,233],"eccentric":[55,138,258,269],"exercise.":[56,79,105,167,197,234,259,277],"In":[57],"addition,":[58],"interstitial":[59],"stem":[60,65],"cells":[61,66],"characterized":[62],"as":[63],"mesenchymal":[64],"(MSCs)":[67],"accumulate":[68,264],"\u03b17Tg":[70,101,112,255],"(mMSCs)":[72],"sedentary":[75,132],"state":[76],"after":[78,104,162,196,257,268],"results":[81,237],"from":[82,111,238],"these":[83],"studies":[84],"prompted":[85],"us":[86],"determine":[88],"extent":[90],"which":[92],"mMSC":[93,222],"underlie":[94],"beneficial":[96,246],"adaptive":[97,274],"responses":[98],"observed":[99],"METHODS:":[106],"mMSCs":[107,127,169,178,243],"(Sca-1CD45)":[108],"were":[109,135,158,210],"isolated":[110],"mice,":[113],"dye-labeled,":[114],"intramuscularly":[116],"injected":[117],"into":[118],"adult":[119],"wild":[120],"type":[121],"recipient":[122],"mice.":[123],"After":[124],"injection":[125,179],"saline,":[129],"remained":[131],"(SED)":[133],"subjected":[136],"exercise":[139],"training":[140],"(TR)":[141],"(downhill":[142],"running)":[143],"on":[144],"treadmill":[146],"(three":[147],"times":[148],"per":[149],"week)":[150],"for":[151],"2":[152,194],"4":[154,220],"wk.":[155,221],"Gastrocnemius-soleus":[156],"complexes":[157],"collected":[159],"24":[160],"h":[161],"last":[164],"bout":[165],"RESULTS:":[168],"did":[170,224],"not":[171,225],"directly":[172],"fuse":[173],"with":[174,189,215],"existing":[175],"fibers;":[176],"however,":[177],"Pax7":[181],"number":[184],"myonuclear":[186],"content":[187],"compared":[188,214],"all":[190],"other":[191],"groups":[192],"at":[193,219],"wk":[195],"Mean":[198],"CSA,":[199],"percentage":[200],"larger":[202],"caliber":[203],"fibers":[204],"(>3000":[205],"\u03bcm),":[206],"grip":[208],"strength":[209],"increased":[211],"mMSCs/TR":[213],"saline/SED":[216],"mMSCs/SED":[218],"transplantation":[223],"enhance":[226,272],"repair":[227],"absence":[232],"CONCLUSIONS:":[235],"this":[239],"study":[240],"demonstrate":[241],"contribute":[244],"changes":[247],"expansion":[251],"Thus,":[260],"MSCs":[261],"naturally":[263],"contractions":[270],"may":[271]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}