{"id":"https://openalex.org/W2002206403","doi":"https://doi.org/10.1016/0306-4530(85)90055-1","title":"Melatonin, cortisol and ACTH in patients with major depressive disorder and healthy humans with special reference to the outcome of the dexamethasone suppression test","display_name":"Melatonin, cortisol and ACTH in patients with major depressive disorder and healthy humans with special reference to the outcome of the dexamethasone suppression test","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W2002206403","doi":"https://doi.org/10.1016/0306-4530(85)90055-1","mag":"2002206403","pmid":"https://pubmed.ncbi.nlm.nih.gov/2994141"},"language":"en","primary_location":{"id":"doi:10.1016/0306-4530(85)90055-1","doi":"https://doi.org/10.1016/0306-4530(85)90055-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4530(85)90055-1","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086295950","display_name":"Johan Beck-Friis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johan Beck-Friis","raw_affiliation_strings":["Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]},{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108218163","display_name":"Jan\u2010Gustaf Ljunggren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jan-Gustaf Ljunggren","raw_affiliation_strings":["Department of Medicine (Endocrine Unit), Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine (Endocrine Unit), Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103533003","display_name":"Marja C Thor\u00e9n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Marja Thor\u00e9n","raw_affiliation_strings":["Department of Endocrinology, Karolinska Hospital, S-104 01 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Karolinska Hospital, S-104 01 Stockholm, Sweden","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030741280","display_name":"Dietrich von Rosen","orcid":"https://orcid.org/0000-0002-3135-4325","observed_orcids":["https://orcid.org/0000-0002-3135-4325"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Dietrich von Rosen","raw_affiliation_strings":["Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]},{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113648794","display_name":"Bengt Kjellman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bengt F. Kjellman","raw_affiliation_strings":["Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]},{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019872747","display_name":"Lennart Wetterberg","orcid":"https://orcid.org/0000-0001-7656-7458","observed_orcids":["https://orcid.org/0000-0001-7656-7458"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lennart Wetterberg","raw_affiliation_strings":["Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St G\u00f6ran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]},{"raw_affiliation_string":"Department of Psychiatry, Karolinska Institute, St Goran's Hospital, S-112 81 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210099778"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":3.5415,"has_fulltext":false,"cited_by_count":138,"citation_normalized_percentile":{"value":0.92743106,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"2","first_page":"173","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9629999995231628},{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.8500000238418579},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.9079999923706055},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.996999979019165},{"id":"https://openalex.org/keywords/dexamethasone-suppression-test","display_name":"dexamethasone suppression test","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/nocturnal-melatonin","display_name":"nocturnal melatonin","score":0.7509999871253967},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.5170000195503235},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.6840000152587891},{"id":"https://openalex.org/keywords/bipolar-depression","display_name":"bipolar depression","score":0.5289999842643738},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.8679999709129333},{"id":"https://openalex.org/keywords/pituitary-desensitization","display_name":"pituitary desensitization","score":0.968999981880188},{"id":"https://openalex.org/keywords/trait-markers","display_name":"trait markers","score":0.6549999713897705},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.4869999885559082},{"id":"https://openalex.org/keywords/depression-biomarkers","display_name":"depression biomarkers","score":0.3889999985694885},{"id":"https://openalex.org/keywords/hpa-axis-hyperactivity","display_name":"HPA axis hyperactivity","score":0.4050000011920929}],"concepts":[{"id":"https://openalex.org/C2780455818","wikidata":"https://www.wikidata.org/wiki/Q1207196","display_name":"Dexamethasone suppression test","level":3,"score":0.7601335048675537},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.7176423072814941},{"id":"https://openalex.org/C2780401358","wikidata":"https://www.wikidata.org/wiki/Q422252","display_name":"Dexamethasone","level":2,"score":0.6741368174552917},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.603374183177948},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.5963725447654724},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5363017320632935},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5060901045799255},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4793475568294525},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4565155506134033},{"id":"https://openalex.org/C2778709874","wikidata":"https://www.wikidata.org/wiki/Q190875","display_name":"Hydrocortisone","level":2,"score":0.4496111571788788},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008550","descriptor_name":"Melatonin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0306-4530(85)90055-1","doi":"https://doi.org/10.1016/0306-4530(85)90055-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4530(85)90055-1","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},{"id":"pmid:2994141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2994141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W169773053","https://openalex.org/W605532336","https://openalex.org/W627977585","https://openalex.org/W1500276767","https://openalex.org/W1794165588","https://openalex.org/W1965543679","https://openalex.org/W1978513029","https://openalex.org/W1983544699","https://openalex.org/W1989360653","https://openalex.org/W2001407351","https://openalex.org/W2001444665","https://openalex.org/W2010425653","https://openalex.org/W2019582803","https://openalex.org/W2036276544","https://openalex.org/W2039700748","https://openalex.org/W2049165791","https://openalex.org/W2053625428","https://openalex.org/W2056601870","https://openalex.org/W2057466848","https://openalex.org/W2067363258","https://openalex.org/W2070797448","https://openalex.org/W2073681121","https://openalex.org/W2074185602","https://openalex.org/W2080889861","https://openalex.org/W2108892576","https://openalex.org/W2166456361","https://openalex.org/W2263270175","https://openalex.org/W2340743353","https://openalex.org/W2404019172","https://openalex.org/W2409872150","https://openalex.org/W2475338734","https://openalex.org/W2809193664","https://openalex.org/W4230839768","https://openalex.org/W6692968113"],"related_works":["https://openalex.org/W2164136574","https://openalex.org/W2047080801","https://openalex.org/W1964260246","https://openalex.org/W2166347315","https://openalex.org/W2121256949","https://openalex.org/W2014480103","https://openalex.org/W2004283056","https://openalex.org/W2059820745","https://openalex.org/W2091041090","https://openalex.org/W2165668731"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}