{"id":"https://openalex.org/W2002195973","doi":"https://doi.org/10.1016/0378-5955(87)90081-5","title":"Kynurenic acid and \u03b3-D-glutamylaminomethylsulfonic acid suppress the compound action potential of the auditory nerve","display_name":"Kynurenic acid and \u03b3-D-glutamylaminomethylsulfonic acid suppress the compound action potential of the auditory nerve","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2002195973","doi":"https://doi.org/10.1016/0378-5955(87)90081-5","mag":"2002195973","pmid":"https://pubmed.ncbi.nlm.nih.gov/2879824"},"language":"en","primary_location":{"id":"doi:10.1016/0378-5955(87)90081-5","doi":"https://doi.org/10.1016/0378-5955(87)90081-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-5955(87)90081-5","pdf_url":null,"source":{"id":"https://openalex.org/S82774605","display_name":"Hearing Research","issn_l":"0378-5955","issn":["0378-5955","1878-5891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010989211","display_name":"Richard P. Bobbin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I2801463575","display_name":"University Medical Center New Orleans","ror":"https://ror.org/02zrb2v54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I2801463575","https://openalex.org/I75420490"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard P. Bobbin","raw_affiliation_strings":["Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology and Biocommunication, Louisiana State University Medical Center, New Orleans, LA 70119-2799, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology and Biocommunication, Louisiana State University Medical Center, New Orleans, LA 70119-2799, U.S.A","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I2801463575","https://openalex.org/I75420490"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085205100","display_name":"Gail Ceasar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I2801463575","display_name":"University Medical Center New Orleans","ror":"https://ror.org/02zrb2v54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I2801463575","https://openalex.org/I75420490"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gail Ceasar","raw_affiliation_strings":["Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology and Biocommunication, Louisiana State University Medical Center, New Orleans, LA 70119-2799, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology and Biocommunication, Louisiana State University Medical Center, New Orleans, LA 70119-2799, U.S.A","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I2801463575","https://openalex.org/I75420490"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5010989211"],"corresponding_institution_ids":["https://openalex.org/I121820613","https://openalex.org/I2801463575","https://openalex.org/I75420490"],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":4.463,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.95952782,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"25","issue":"1","first_page":"77","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kynurenic-acid","display_name":"kynurenic acid","score":1.0},{"id":"https://openalex.org/keywords/excitatory-amino-acid-antagonists","display_name":"excitatory amino acid antagonists","score":0.8999999761581421},{"id":"https://openalex.org/keywords/compound-action-potential","display_name":"compound action potential","score":0.9800000190734863},{"id":"https://openalex.org/keywords/auditory-nerve","display_name":"auditory nerve","score":0.8579999804496765},{"id":"https://openalex.org/keywords/cochlear-potentials","display_name":"cochlear potentials","score":0.8299999833106995},{"id":"https://openalex.org/keywords/glutamate","display_name":"glutamate","score":0.9539999961853027},{"id":"https://openalex.org/keywords/cochlea","display_name":"cochlea","score":0.628000020980835},{"id":"https://openalex.org/keywords/guinea-pig","display_name":"guinea pig","score":0.8199999928474426}],"concepts":[{"id":"https://openalex.org/C2776841986","wikidata":"https://www.wikidata.org/wiki/Q642217","display_name":"Kynurenic acid","level":4,"score":0.9496309757232666},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.8224461078643799},{"id":"https://openalex.org/C151626666","wikidata":"https://www.wikidata.org/wiki/Q5156844","display_name":"Compound muscle action potential","level":3,"score":0.8126392960548401},{"id":"https://openalex.org/C2780130748","wikidata":"https://www.wikidata.org/wiki/Q317857","display_name":"Cochlea","level":2,"score":0.5813227891921997},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.5443730354309082},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5129051208496094},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.49736741185188293},{"id":"https://openalex.org/C2776796419","wikidata":"https://www.wikidata.org/wiki/Q2519137","display_name":"Cochlear nerve","level":3,"score":0.4383728504180908},{"id":"https://openalex.org/C2778815084","wikidata":"https://www.wikidata.org/wiki/Q79803","display_name":"Guinea pig","level":2,"score":0.4225609600543976},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.37148618698120117},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3571934700012207},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2861955761909485},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.284270316362381},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.215699702501297},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1707768738269806},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11266550421714783}],"mesh":[{"descriptor_ui":"D000159","descriptor_name":"Vestibulocochlear Nerve","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003051","descriptor_name":"Cochlea","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003055","descriptor_name":"Cochlear Microphonic Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005973","descriptor_name":"Glutamine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006198","descriptor_name":"Hair Cells, Auditory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006198","descriptor_name":"Hair Cells, Auditory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007736","descriptor_name":"Kynurenic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0378-5955(87)90081-5","doi":"https://doi.org/10.1016/0378-5955(87)90081-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-5955(87)90081-5","pdf_url":null,"source":{"id":"https://openalex.org/S82774605","display_name":"Hearing Research","issn_l":"0378-5955","issn":["0378-5955","1878-5891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing Research","raw_type":"journal-article"},{"id":"pmid:2879824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2879824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1502934874","https://openalex.org/W1523130029","https://openalex.org/W1566585200","https://openalex.org/W1608159615","https://openalex.org/W1870728755","https://openalex.org/W1965491364","https://openalex.org/W1984770449","https://openalex.org/W1995982968","https://openalex.org/W1999261297","https://openalex.org/W2002204474","https://openalex.org/W2014447344","https://openalex.org/W2016239889","https://openalex.org/W2021162627","https://openalex.org/W2026606626","https://openalex.org/W2037834995","https://openalex.org/W2048910157","https://openalex.org/W2056820399","https://openalex.org/W2064701360","https://openalex.org/W2069873922","https://openalex.org/W2087098131","https://openalex.org/W2091970325","https://openalex.org/W2115367358","https://openalex.org/W2138229062","https://openalex.org/W2144273596","https://openalex.org/W4254503887","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1995982968","https://openalex.org/W2149960259","https://openalex.org/W2047060305","https://openalex.org/W2091970325","https://openalex.org/W2034387592","https://openalex.org/W2100188118","https://openalex.org/W3186115535","https://openalex.org/W2067819579","https://openalex.org/W2034279703","https://openalex.org/W2060516018"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}