{"id":"https://openalex.org/W2002189373","doi":"https://doi.org/10.1109/memb.2007.335593","title":"A comprehensive human chromosome 21 database","display_name":"A comprehensive human chromosome 21 database","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W2002189373","doi":"https://doi.org/10.1109/memb.2007.335593","mag":"2002189373","pmid":"https://pubmed.ncbi.nlm.nih.gov/17441613"},"language":"en","primary_location":{"id":"doi:10.1109/memb.2007.335593","doi":"https://doi.org/10.1109/memb.2007.335593","is_oa":false,"landing_page_url":"https://doi.org/10.1109/memb.2007.335593","pdf_url":null,"source":{"id":"https://openalex.org/S20334542","display_name":"IEEE Engineering in Medicine and Biology Magazine","issn_l":"0739-5175","issn":["0739-5175","1937-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310322504","host_organization_name":"IEEE Engineering in Medicine and Biology Society","host_organization_lineage":["https://openalex.org/P4310322504","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Engineering in Medicine and Biology Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Engineering in Medicine and Biology Magazine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102149345","display_name":"Cao Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cao Nguyen","raw_affiliation_strings":["University of Colorado at Denver and Health Sciences Center, 80217-3364, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado at Denver and Health Sciences Center, 80217-3364, USA","institution_ids":["https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024078921","display_name":"Supphachai Thaicharoen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Supphachai Thaicharoen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102964409","display_name":"Thomas Lacroix","orcid":"https://orcid.org/0000-0002-6708-5809","observed_orcids":["https://orcid.org/0000-0002-6708-5809"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Lacroix","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032439981","display_name":"Katheleen Gardiner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katheleen Gardiner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5090721600","display_name":"Krzysztof J. Cios","orcid":"https://orcid.org/0000-0001-5808-5316","observed_orcids":["https://orcid.org/0000-0001-5808-5316"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krzysztof Cios","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1412,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.47333333,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"2","first_page":"86","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.43140000104904175,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.43140000104904175,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.22020000219345093,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.02710000053048134,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-chromosome-21","display_name":"chromosome 21","score":0.9079999923706055},{"id":"https://openalex.org/keywords/down-syndrome","display_name":"Down syndrome","score":0.847000002861023},{"id":"https://openalex.org/keywords/genetic-databases","display_name":"genetic databases","score":0.3569999933242798}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5228553414344788},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38492661714553833},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.36804941296577454},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2573387324810028}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002891","descriptor_name":"Chromosomes, Human, Pair 21","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/memb.2007.335593","doi":"https://doi.org/10.1109/memb.2007.335593","is_oa":false,"landing_page_url":"https://doi.org/10.1109/memb.2007.335593","pdf_url":null,"source":{"id":"https://openalex.org/S20334542","display_name":"IEEE Engineering in Medicine and Biology Magazine","issn_l":"0739-5175","issn":["0739-5175","1937-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310322504","host_organization_name":"IEEE Engineering in Medicine and Biology Society","host_organization_lineage":["https://openalex.org/P4310322504","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Engineering in Medicine and Biology Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Engineering in Medicine and Biology Magazine","raw_type":"journal-article"},{"id":"pmid:17441613","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17441613","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society","raw_type":"Journal Article"},{"id":"mag:2120282140","doi":null,"is_oa":false,"landing_page_url":"http://ieeexplore.ieee.org/articleDetails.jsp?arnumber=4135805","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1486817521","https://openalex.org/W1994803330","https://openalex.org/W2090766471","https://openalex.org/W2099275700","https://openalex.org/W2119043225","https://openalex.org/W2155225302","https://openalex.org/W2158714788","https://openalex.org/W2161734235","https://openalex.org/W2614575602","https://openalex.org/W3199143553"],"related_works":["https://openalex.org/W44671708","https://openalex.org/W4300014449","https://openalex.org/W2120282140","https://openalex.org/W2783001685","https://openalex.org/W2410078745","https://openalex.org/W2072734450","https://openalex.org/W2776228345","https://openalex.org/W7047032956","https://openalex.org/W2467467932","https://openalex.org/W1633753431"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}