{"id":"https://openalex.org/W2002117372","doi":"https://doi.org/10.1016/s0960-7404(96)80009-0","title":"Increased levels of serum intercellular adhesion molecule-1 (ICAM-1) in patients with non-small cell lung cancer","display_name":"Increased levels of serum intercellular adhesion molecule-1 (ICAM-1) in patients with non-small cell lung cancer","publication_year":1996,"publication_date":"1996-06-01","ids":{"openalex":"https://openalex.org/W2002117372","doi":"https://doi.org/10.1016/s0960-7404(96)80009-0","mag":"2002117372","pmid":"https://pubmed.ncbi.nlm.nih.gov/8908715"},"language":"en","primary_location":{"id":"doi:10.1016/s0960-7404(96)80009-0","doi":"https://doi.org/10.1016/s0960-7404(96)80009-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0960-7404(96)80009-0","pdf_url":null,"source":{"id":"https://openalex.org/S30308013","display_name":"Surgical Oncology","issn_l":"0960-7404","issn":["0960-7404","1879-3320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113579000","display_name":"T Osaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"T. Osaki","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081110935","display_name":"Tetsuya Mitsudomi","orcid":"https://orcid.org/0000-0001-9860-8505","observed_orcids":["https://orcid.org/0000-0001-9860-8505"]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]},{"id":"https://openalex.org/I4210133851","display_name":"Aichi Cancer Center","ror":"https://ror.org/03kfmm080","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210133851"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Mitsudomi","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","General Thoracic Surgery, Aichi Cancer Center, Nagoya, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]},{"raw_affiliation_string":"General Thoracic Surgery, Aichi Cancer Center, Nagoya, Japan","institution_ids":["https://openalex.org/I4210133851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069519198","display_name":"Yasunori Yoshida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Yoshida","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109071987","display_name":"Tsunehiro Oyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Oyama","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110512692","display_name":"A. Ohgami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. Ohgami","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015517523","display_name":"Kozo Nakanishi","orcid":"https://orcid.org/0000-0003-1911-342X","observed_orcids":["https://orcid.org/0000-0003-1911-342X"]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Nakanishi","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084121742","display_name":"Ryoichi Nakanishi","orcid":"https://orcid.org/0000-0003-2259-5941","observed_orcids":["https://orcid.org/0000-0003-2259-5941"]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"R. Nakanishi","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019175407","display_name":"Kenji Sugio","orcid":"https://orcid.org/0000-0002-9940-5897","observed_orcids":["https://orcid.org/0000-0002-9940-5897"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]},{"id":"https://openalex.org/I4210097767","display_name":"Kyushu University Hospital","ror":"https://ror.org/00ex2fc97","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I135598925","https://openalex.org/I4210097767"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Sugio","raw_affiliation_strings":["Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925","https://openalex.org/I4210097767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052578079","display_name":"Kosei Yasumoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188700360","display_name":"University of Occupational and Environmental Health Japan","ror":"https://ror.org/020p3h829","country_code":"JP","type":"education","lineage":["https://openalex.org/I188700360"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Yasumoto","raw_affiliation_strings":["Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan","institution_ids":["https://openalex.org/I188700360"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5113579000"],"corresponding_institution_ids":["https://openalex.org/I188700360"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":0.1442,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.446,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"5","issue":"3","first_page":"107","last_page":"113"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.649399995803833,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.649399995803833,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.33739998936653137,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/icam-1","display_name":"ICAM-1","score":0.9449999928474426},{"id":"https://openalex.org/keywords/soluble-icam-1","display_name":"soluble ICAM-1","score":0.9860000014305115},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9729999899864197},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.8709999918937683},{"id":"https://openalex.org/keywords/tumor-size","display_name":"tumor size","score":0.8629999756813049},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9470000267028809},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.8859999775886536}],"concepts":[{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7629289627075195},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6201953291893005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6165086627006531},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5962428450584412},{"id":"https://openalex.org/C185946421","wikidata":"https://www.wikidata.org/wiki/Q3146527","display_name":"ICAM-1","level":3,"score":0.49941205978393555},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4712531864643097},{"id":"https://openalex.org/C2909375385","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Intercellular Adhesion Molecule-1","level":3,"score":0.4542927145957947},{"id":"https://openalex.org/C3020081911","wikidata":"https://www.wikidata.org/wiki/Q3918988","display_name":"Serum concentration","level":2,"score":0.4476255774497986},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36997994780540466},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3499426543712616},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.294433057308197},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2391025722026825},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2314237356185913},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.11534854769706726}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018799","descriptor_name":"Intercellular Adhesion Molecule-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0960-7404(96)80009-0","doi":"https://doi.org/10.1016/s0960-7404(96)80009-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0960-7404(96)80009-0","pdf_url":null,"source":{"id":"https://openalex.org/S30308013","display_name":"Surgical Oncology","issn_l":"0960-7404","issn":["0960-7404","1879-3320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Oncology","raw_type":"journal-article"},{"id":"pmid:8908715","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8908715","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical oncology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1530281430","https://openalex.org/W1578124425","https://openalex.org/W1594236182","https://openalex.org/W1964264035","https://openalex.org/W1966286149","https://openalex.org/W1969124499","https://openalex.org/W1975549289","https://openalex.org/W1979300931","https://openalex.org/W1983338308","https://openalex.org/W1984890362","https://openalex.org/W2007027096","https://openalex.org/W2015037737","https://openalex.org/W2024588069","https://openalex.org/W2032620608","https://openalex.org/W2038252730","https://openalex.org/W2057784785","https://openalex.org/W2061544823","https://openalex.org/W2063321064","https://openalex.org/W2064717551","https://openalex.org/W2075380738","https://openalex.org/W2080929779","https://openalex.org/W2085684234","https://openalex.org/W2093830420","https://openalex.org/W2129726423","https://openalex.org/W2213537831","https://openalex.org/W2465094164","https://openalex.org/W3041047318","https://openalex.org/W4302341942","https://openalex.org/W6631639059","https://openalex.org/W6634824374","https://openalex.org/W6635479423"],"related_works":["https://openalex.org/W2086799367","https://openalex.org/W2370188653","https://openalex.org/W2053069370","https://openalex.org/W2400871914","https://openalex.org/W2384055017","https://openalex.org/W2349107712","https://openalex.org/W2374052446","https://openalex.org/W2109688183","https://openalex.org/W2355239798","https://openalex.org/W2045360180"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}