{"id":"https://openalex.org/W2002113106","doi":"https://doi.org/10.7732/kjpr.2014.27.3.223","title":"Potential Biological Activities of Magnoflorine: A Compound from Aristolochia debilis Sieb. et Zucc","display_name":"Potential Biological Activities of Magnoflorine: A Compound from Aristolochia debilis Sieb. et Zucc","publication_year":2014,"publication_date":"2014-06-30","ids":{"openalex":"https://openalex.org/W2002113106","doi":"https://doi.org/10.7732/kjpr.2014.27.3.223","mag":"2002113106"},"language":"en","primary_location":{"id":"doi:10.7732/kjpr.2014.27.3.223","doi":"https://doi.org/10.7732/kjpr.2014.27.3.223","is_oa":true,"landing_page_url":"https://doi.org/10.7732/kjpr.2014.27.3.223","pdf_url":"http://koreascience.or.kr:80/article/JAKO201422354180080.pdf","source":{"id":"https://openalex.org/S4306496521","display_name":"\ud55c\uad6d\uc790\uc6d0\uc2dd\ubb3c\ud559\ud68c\uc9c0","issn_l":"1226-3591","issn":["1226-3591","1226-8771","2287-8203"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Plant Resources","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://koreascience.or.kr:80/article/JAKO201422354180080.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100427235","display_name":"Chunmei Li","orcid":"https://orcid.org/0000-0002-6860-3807","observed_orcids":["https://orcid.org/0000-0002-6860-3807"]},"institutions":[{"id":"https://openalex.org/I89015989","display_name":"Dankook University","ror":"https://ror.org/058pdbn81","country_code":"KR","type":"education","lineage":["https://openalex.org/I89015989"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chunmei Li","raw_affiliation_strings":["Department of Food Science and Nutrition , Dankook University , Yongin- Si 448-701 , Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science and Nutrition , Dankook University , Yongin- Si 448-701 , Korea","institution_ids":["https://openalex.org/I89015989"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011447987","display_name":"Myeong\u2010Hyeon Wang","orcid":"https://orcid.org/0000-0003-1760-1622","observed_orcids":["https://orcid.org/0000-0003-1760-1622"]},"institutions":[{"id":"https://openalex.org/I165507594","display_name":"Kangwon National University","ror":"https://ror.org/01mh5ph17","country_code":"KR","type":"education","lineage":["https://openalex.org/I165507594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Myeong-Hyeon Wang","raw_affiliation_strings":["Department of MedicaBiotechnology , Kangwon National University , Chuncheon 200-701 , Korea","Kangwon National University;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of MedicaBiotechnology , Kangwon National University , Chuncheon 200-701 , Korea","institution_ids":["https://openalex.org/I165507594"]},{"raw_affiliation_string":"Kangwon National University;","institution_ids":["https://openalex.org/I165507594"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3709,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.65441125,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"27","issue":"3","first_page":"223","last_page":"228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.4652999937534332,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.4652999937534332,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.14990000426769257,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.1340000033378601,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnoflorine","display_name":"magnoflorine","score":1.0},{"id":"https://openalex.org/keywords/aristolochia-debilis","display_name":"Aristolochia debilis","score":1.0},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7409999966621399},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/nitric-oxide-inhibition","display_name":"nitric oxide inhibition","score":0.8529999852180481},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.9750000238418579},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8740000128746033},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.8820000290870667},{"id":"https://openalex.org/keywords/dpph-radical-scavenging-activity","display_name":"DPPH radical scavenging","score":0.8799999952316284},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8634831309318542},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.5887011885643005},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5728340744972229},{"id":"https://openalex.org/C87554066","wikidata":"https://www.wikidata.org/wiki/Q85942926","display_name":"Tyrosinase","level":3,"score":0.5282389521598816},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.4757080674171448},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.47549518942832947},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3349105715751648},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.33362746238708496},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08481508493423462},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05787944793701172},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7732/kjpr.2014.27.3.223","doi":"https://doi.org/10.7732/kjpr.2014.27.3.223","is_oa":true,"landing_page_url":"https://doi.org/10.7732/kjpr.2014.27.3.223","pdf_url":"http://koreascience.or.kr:80/article/JAKO201422354180080.pdf","source":{"id":"https://openalex.org/S4306496521","display_name":"\ud55c\uad6d\uc790\uc6d0\uc2dd\ubb3c\ud559\ud68c\uc9c0","issn_l":"1226-3591","issn":["1226-3591","1226-8771","2287-8203"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Plant Resources","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.892.635","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.892.635","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ocean.kisti.re.kr/downfile/volume/prsk/JOSMBA/2014/v27n3/JOSMBA_2014_v27n3_223.pdf","raw_type":"text"},{"id":"mag:1529852496","doi":null,"is_oa":false,"landing_page_url":"http://www.dbpia.co.kr/Journal/ArticleDetail/NODE02428382","pdf_url":null,"source":{"id":"https://openalex.org/S4306496521","display_name":"\ud55c\uad6d\uc790\uc6d0\uc2dd\ubb3c\ud559\ud68c\uc9c0","issn_l":"1226-3591","issn":["1226-3591","1226-8771","2287-8203"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\ud55c\uad6d\uc790\uc6d0\uc2dd\ubb3c\ud559\ud68c\uc9c0","raw_type":null}],"best_oa_location":{"id":"doi:10.7732/kjpr.2014.27.3.223","doi":"https://doi.org/10.7732/kjpr.2014.27.3.223","is_oa":true,"landing_page_url":"https://doi.org/10.7732/kjpr.2014.27.3.223","pdf_url":"http://koreascience.or.kr:80/article/JAKO201422354180080.pdf","source":{"id":"https://openalex.org/S4306496521","display_name":"\ud55c\uad6d\uc790\uc6d0\uc2dd\ubb3c\ud559\ud68c\uc9c0","issn_l":"1226-3591","issn":["1226-3591","1226-8771","2287-8203"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Plant Resources","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2002113106.pdf","grobid_xml":"https://content.openalex.org/works/W2002113106.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W190537952","https://openalex.org/W1847621516","https://openalex.org/W1967155261","https://openalex.org/W1980399128","https://openalex.org/W1986912326","https://openalex.org/W1996444406","https://openalex.org/W1997665025","https://openalex.org/W2011041824","https://openalex.org/W2011231246","https://openalex.org/W2021647627","https://openalex.org/W2047199334","https://openalex.org/W2056591808","https://openalex.org/W2059545351","https://openalex.org/W2064091240","https://openalex.org/W2068768714","https://openalex.org/W2071866695","https://openalex.org/W2075873470","https://openalex.org/W2089906718","https://openalex.org/W2100838948","https://openalex.org/W2137080770","https://openalex.org/W2159912770","https://openalex.org/W2171731254","https://openalex.org/W2216001434"],"related_works":["https://openalex.org/W1529852496","https://openalex.org/W7127107636","https://openalex.org/W2883065105","https://openalex.org/W2216001434","https://openalex.org/W2997347248","https://openalex.org/W2052911465","https://openalex.org/W3136438659","https://openalex.org/W2161357418","https://openalex.org/W2605490315","https://openalex.org/W2317981559"],"abstract_inverted_index":{"Magnoflorine,":[0],"an":[1,10],"important":[2],"compound":[3],"in":[4],"Aristolochia,":[5],"was":[6,18,65,113],"usually":[7],"used":[8],"as":[9,27,44],"anxiolytic":[11],"chemical.":[12],"In":[13],"this":[14],"study,":[15],"the":[16,23,53,60,73,78,85,92,95],"magnoflorine":[17,39,54,74,83,93,126],"isolated":[19],"from":[20,101],"Aristolochia":[21],"and":[22,33,91],"biological":[24],"activities":[25,35],"such":[26],"antioxidant,":[28],"${\\alpha}$":[29,68],"-tyrosinase":[30,69],"inhibitory,":[31],"anti-inflammatory,":[32],"anticancer":[34,129],"were":[36],"investigated.":[37],"The":[38,104],"showed":[40],"significant":[41],"antioxidant":[42],"activity":[43],"a":[45],"2,2-diphenyl-2-picryl-hydrazyl":[46],"(DPPH)":[47],"free":[48,61],"radical":[49],"scavenger,":[50],"$50{\\mu}g/mL$":[51],"of":[52,58,72,77,82,107,121],"scavenged":[55],"about":[56],"70.8%":[57],"all":[59],"radicals.":[62],"And":[63],"it":[64],"good":[66],"at":[67],"inhibiting,":[70],"$100{\\mu}g/mL$":[71],"inhibited":[75,84],"36.5%":[76],"tyrosinase.":[79],"High":[80],"dosage":[81],"inflammation":[86],"production":[87],"nitric":[88],"oxide":[89],"(NO),":[90],"protected":[94],"murine":[96],"macrophage":[97],"cells":[98],"(RAW":[99],"264.7)":[100],"LPS-induced":[102],"apoptosis.":[103],"cell":[105],"viability":[106],"human":[108],"colon":[109],"cancer":[110],"calls":[111],"(HT-29)":[112],"around":[114],"100%":[115],"when":[116],"treated":[117],"with":[118],"different":[119],"dose":[120],"magnoflorine,":[122],"it's":[123],"suggesting":[124],"that":[125],"had":[127],"no":[128],"effect.":[130]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}