{"id":"https://openalex.org/W2002045314","doi":"https://doi.org/10.1007/s11864-012-0190-8","title":"Therapeutic Strategies for Bone Metastases and Their Clinical Sequelae in Prostate Cancer","display_name":"Therapeutic Strategies for Bone Metastases and Their Clinical Sequelae in Prostate Cancer","publication_year":2012,"publication_date":"2012-04-24","ids":{"openalex":"https://openalex.org/W2002045314","doi":"https://doi.org/10.1007/s11864-012-0190-8","mag":"2002045314","pmid":"https://pubmed.ncbi.nlm.nih.gov/22528368","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3652976"},"language":"en","primary_location":{"id":"doi:10.1007/s11864-012-0190-8","doi":"https://doi.org/10.1007/s11864-012-0190-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11864-012-0190-8","pdf_url":null,"source":{"id":"https://openalex.org/S208090617","display_name":"Current Treatment Options in Oncology","issn_l":"1527-2729","issn":["1527-2729","1534-6277"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Treatment Options in Oncology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3652976","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090778997","display_name":"Karen A. Autio","orcid":"https://orcid.org/0000-0003-0720-0390","observed_orcids":["https://orcid.org/0000-0003-0720-0390"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen A. Autio","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072850546","display_name":"Howard I. Scher","orcid":"https://orcid.org/0000-0002-6791-9324","observed_orcids":["https://orcid.org/0000-0002-6791-9324"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard I. Scher","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA","Memorial Sloan-Kettering Cancer Center New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center New York USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017288060","display_name":"Michael J. Morris","orcid":"https://orcid.org/0000-0002-9454-0096","observed_orcids":["https://orcid.org/0000-0002-9454-0096"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael J. Morris","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA","Memorial Sloan-Kettering Cancer Center New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center New York USA","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017288060"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":4890,"currency":"USD","value_usd":4890},"apc_paid":null,"fwci":0.7038,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.58178506,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"13","issue":"2","first_page":"174","last_page":"188"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.14749999344348907,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.9620000123977661},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.8730000257492065},{"id":"https://openalex.org/keywords/skeletal-related-events","display_name":"skeletal-related events","score":0.8970000147819519},{"id":"https://openalex.org/keywords/bone-pain","display_name":"bone pain","score":0.5170000195503235},{"id":"https://openalex.org/keywords/radium-223","display_name":"radium-223","score":0.9330000281333923},{"id":"https://openalex.org/keywords/samarium-153-edtmp","display_name":"samarium-153 EDTMP","score":0.9850000143051147},{"id":"https://openalex.org/keywords/strontium-89","display_name":"strontium-89","score":1.0},{"id":"https://openalex.org/keywords/bisphosphonates","display_name":"bisphosphonates","score":0.8820000290870667},{"id":"https://openalex.org/keywords/denosumab","display_name":"denosumab","score":0.8460000157356262},{"id":"https://openalex.org/keywords/zoledronic-acid","display_name":"zoledronic acid","score":0.7149999737739563},{"id":"https://openalex.org/keywords/fracture-prevention","display_name":"fracture prevention","score":0.47600001096725464},{"id":"https://openalex.org/keywords/c-met","display_name":"c-Met","score":0.7170000076293945},{"id":"https://openalex.org/keywords/src-kinase","display_name":"Src kinase","score":0.9750000238418579}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9410003423690796},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.739534854888916},{"id":"https://openalex.org/C2776139714","wikidata":"https://www.wikidata.org/wiki/Q3480107","display_name":"Bone pain","level":2,"score":0.5504463911056519},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5062083601951599},{"id":"https://openalex.org/C2780737065","wikidata":"https://www.wikidata.org/wiki/Q18888805","display_name":"Radium-223","level":5,"score":0.49770548939704895},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4961863160133362},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.47761768102645874},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4365251660346985},{"id":"https://openalex.org/C2776033226","wikidata":"https://www.wikidata.org/wiki/Q828410","display_name":"Osteoclast","level":3,"score":0.4192926287651062},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40594449639320374},{"id":"https://openalex.org/C2777783956","wikidata":"https://www.wikidata.org/wiki/Q848085","display_name":"Bone metastasis","level":4,"score":0.338439404964447},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069448","descriptor_name":"Denosumab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077211","descriptor_name":"Zoledronic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D004164","descriptor_name":"Diphosphonates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009943","descriptor_name":"Organophosphorus Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013324","descriptor_name":"Strontium","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D059408","descriptor_name":"Pain Management","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s11864-012-0190-8","doi":"https://doi.org/10.1007/s11864-012-0190-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11864-012-0190-8","pdf_url":null,"source":{"id":"https://openalex.org/S208090617","display_name":"Current Treatment Options in Oncology","issn_l":"1527-2729","issn":["1527-2729","1534-6277"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Treatment Options in Oncology","raw_type":"journal-article"},{"id":"pmid:22528368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22528368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current treatment options in oncology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2650839","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3652976","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3652976","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3652976","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Treat Options Oncol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2650839","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3652976","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000898892","display_name":"Investigational Cancer Therapeutics Training Program (ICTTP)","funder_award_id":"T32CA009207","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000900620","display_name":"Summer research experiences for medical students supervised by faculty mentors","funder_award_id":"R25CA020449","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W16270628","https://openalex.org/W69365011","https://openalex.org/W174401574","https://openalex.org/W1274170188","https://openalex.org/W1782000195","https://openalex.org/W1854708637","https://openalex.org/W1893347245","https://openalex.org/W1909201457","https://openalex.org/W1917534569","https://openalex.org/W1918406592","https://openalex.org/W1927196455","https://openalex.org/W1935714962","https://openalex.org/W1971660671","https://openalex.org/W1979712686","https://openalex.org/W1980417792","https://openalex.org/W1986170691","https://openalex.org/W1987008543","https://openalex.org/W1988060060","https://openalex.org/W1992053982","https://openalex.org/W2008386697","https://openalex.org/W2027735110","https://openalex.org/W2032489945","https://openalex.org/W2045191690","https://openalex.org/W2048396601","https://openalex.org/W2054042846","https://openalex.org/W2063548091","https://openalex.org/W2065016129","https://openalex.org/W2065916018","https://openalex.org/W2070408871","https://openalex.org/W2079742505","https://openalex.org/W2080439368","https://openalex.org/W2081463541","https://openalex.org/W2083750790","https://openalex.org/W2084252817","https://openalex.org/W2088565634","https://openalex.org/W2102397607","https://openalex.org/W2103314990","https://openalex.org/W2103959341","https://openalex.org/W2104923745","https://openalex.org/W2107925414","https://openalex.org/W2110534364","https://openalex.org/W2110707581","https://openalex.org/W2113556350","https://openalex.org/W2119185578","https://openalex.org/W2119263434","https://openalex.org/W2120292596","https://openalex.org/W2123526148","https://openalex.org/W2125752165","https://openalex.org/W2130879093","https://openalex.org/W2136390065","https://openalex.org/W2136505615","https://openalex.org/W2136646477","https://openalex.org/W2139232028","https://openalex.org/W2139860898","https://openalex.org/W2147376175","https://openalex.org/W2149547695","https://openalex.org/W2149775776","https://openalex.org/W2158639339","https://openalex.org/W2165011173","https://openalex.org/W2165088640","https://openalex.org/W2167331614","https://openalex.org/W2168533928","https://openalex.org/W2171111087","https://openalex.org/W2227075123","https://openalex.org/W2401709656","https://openalex.org/W2409003443","https://openalex.org/W2589132608","https://openalex.org/W2607028219"],"related_works":["https://openalex.org/W2527022083","https://openalex.org/W136751265","https://openalex.org/W2134463877","https://openalex.org/W1517224081","https://openalex.org/W2777246006","https://openalex.org/W2019289198","https://openalex.org/W2004538226","https://openalex.org/W2258044145","https://openalex.org/W3089515600","https://openalex.org/W2912758842"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}