{"id":"https://openalex.org/W2001936110","doi":"https://doi.org/10.1038/eye.2011.172","title":"Optic disc classification by the Heidelberg Retina Tomograph and by physicians with varying experience of glaucoma","display_name":"Optic disc classification by the Heidelberg Retina Tomograph and by physicians with varying experience of glaucoma","publication_year":2011,"publication_date":"2011-08-12","ids":{"openalex":"https://openalex.org/W2001936110","doi":"https://doi.org/10.1038/eye.2011.172","mag":"2001936110","pmid":"https://pubmed.ncbi.nlm.nih.gov/21836629","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3213643"},"language":"en","primary_location":{"id":"doi:10.1038/eye.2011.172","doi":"https://doi.org/10.1038/eye.2011.172","is_oa":true,"landing_page_url":"https://doi.org/10.1038/eye.2011.172","pdf_url":"https://www.nature.com/articles/eye2011172.pdf","source":{"id":"https://openalex.org/S167047176","display_name":"Eye","issn_l":"0078-5334","issn":["0078-5334","0950-222X","1476-5454"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eye","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/eye2011172.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084143593","display_name":"Sabina Andersson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"S Andersson","raw_affiliation_strings":["Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden. sabina.andersson@med.lu.se","Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden. sabina.andersson@med.lu.se","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022617905","display_name":"Anders Heijl","orcid":"https://orcid.org/0000-0001-7233-6919","observed_orcids":["https://orcid.org/0000-0001-7233-6919"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"A Heijl","raw_affiliation_strings":["Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042154148","display_name":"Boel Bengtsson","orcid":"https://orcid.org/0000-0002-5997-3953","observed_orcids":["https://orcid.org/0000-0002-5997-3953"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"B Bengtsson","raw_affiliation_strings":["Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Ophthalmology, Lund University, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084143593"],"corresponding_institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":1.7045,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.82940531,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"25","issue":"11","first_page":"1401","last_page":"1407"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glaucoma","display_name":"glaucoma","score":0.8690000176429749},{"id":"https://openalex.org/keywords/heidelberg-retina-tomograph","display_name":"Heidelberg Retina Tomograph","score":0.9890000224113464},{"id":"https://openalex.org/keywords/moorfields-regression-analysis","display_name":"Moorfields regression analysis","score":0.972000002861023},{"id":"https://openalex.org/keywords/glaucoma-probability-score","display_name":"glaucoma probability score","score":0.9980000257492065},{"id":"https://openalex.org/keywords/optic-disc-photographs","display_name":"optic disc photographs","score":0.6309999823570251},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.6729999780654907},{"id":"https://openalex.org/keywords/ophthalmology-residents","display_name":"ophthalmology residents","score":0.7250000238418579},{"id":"https://openalex.org/keywords/disc-size","display_name":"disk size","score":0.6830000281333923},{"id":"https://openalex.org/keywords/visual-field-defects","display_name":"visual field defects","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.8708822727203369},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8327755928039551},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7549557089805603},{"id":"https://openalex.org/C2779735895","wikidata":"https://www.wikidata.org/wiki/Q16873995","display_name":"Optic disc","level":3,"score":0.7352005839347839},{"id":"https://openalex.org/C2776058522","wikidata":"https://www.wikidata.org/wiki/Q2364768","display_name":"Visual field","level":2,"score":0.6521105170249939},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.5738468170166016},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.5311497449874878},{"id":"https://openalex.org/C2983497740","wikidata":"https://www.wikidata.org/wiki/Q16873995","display_name":"Optic disk","level":3,"score":0.4288063049316406},{"id":"https://openalex.org/C147176958","wikidata":"https://www.wikidata.org/wiki/Q77590","display_name":"Civil engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005902","descriptor_name":"Glaucoma, Open-Angle","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007396","descriptor_name":"Internship and Residency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009885","descriptor_name":"Ophthalmology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015588","descriptor_name":"Observer Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/eye.2011.172","doi":"https://doi.org/10.1038/eye.2011.172","is_oa":true,"landing_page_url":"https://doi.org/10.1038/eye.2011.172","pdf_url":"https://www.nature.com/articles/eye2011172.pdf","source":{"id":"https://openalex.org/S167047176","display_name":"Eye","issn_l":"0078-5334","issn":["0078-5334","0950-222X","1476-5454"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eye","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3213643","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3213643","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eye (Lond)","raw_type":"Text"},{"id":"pmid:21836629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21836629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eye (London, England)","raw_type":"Comparative Study"},{"id":"pmh:oai:lup.lub.lu.se:15806597-8f1a-4bec-8ff0-728a21e14aa2","doi":null,"is_oa":true,"landing_page_url":"https://lup.lub.lu.se/record/2151140","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1476-5454","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/eye.2011.172","doi":"https://doi.org/10.1038/eye.2011.172","is_oa":true,"landing_page_url":"https://doi.org/10.1038/eye.2011.172","pdf_url":"https://www.nature.com/articles/eye2011172.pdf","source":{"id":"https://openalex.org/S167047176","display_name":"Eye","issn_l":"0078-5334","issn":["0078-5334","0950-222X","1476-5454"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eye","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5434787064","display_name":null,"funder_award_id":"K2005-74X-10426-13A","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"}],"funders":[{"id":"https://openalex.org/F4320311811","display_name":"Stichting voor de Blinden","ror":null},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2001936110.pdf","grobid_xml":"https://content.openalex.org/works/W2001936110.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W57491163","https://openalex.org/W93186252","https://openalex.org/W960697921","https://openalex.org/W1136486425","https://openalex.org/W1551547454","https://openalex.org/W1588316972","https://openalex.org/W1896510086","https://openalex.org/W1966994577","https://openalex.org/W1979980962","https://openalex.org/W1984761962","https://openalex.org/W1996121998","https://openalex.org/W1999469806","https://openalex.org/W2002202844","https://openalex.org/W2011481648","https://openalex.org/W2032821804","https://openalex.org/W2033021363","https://openalex.org/W2039303389","https://openalex.org/W2046995005","https://openalex.org/W2055206418","https://openalex.org/W2070100803","https://openalex.org/W2072946053","https://openalex.org/W2073317925","https://openalex.org/W2079445482","https://openalex.org/W2085204972","https://openalex.org/W2086168423","https://openalex.org/W2112559287","https://openalex.org/W2114361744","https://openalex.org/W2120019058","https://openalex.org/W2132608953","https://openalex.org/W2140012740","https://openalex.org/W2149903987","https://openalex.org/W2161358060","https://openalex.org/W2168364128","https://openalex.org/W2171736849"],"related_works":["https://openalex.org/W93186252","https://openalex.org/W2070100803","https://openalex.org/W2033021363","https://openalex.org/W1972199859","https://openalex.org/W57491163","https://openalex.org/W7047291970","https://openalex.org/W2531443215","https://openalex.org/W2097524385","https://openalex.org/W2085204972","https://openalex.org/W2122030166"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"compare":[2],"the":[3,7,85,124,144,161,199,218],"diagnostic":[4],"accuracy":[5],"of":[6,23,26,36,192,198,205],"Heidelberg":[8],"Retina":[9],"Tomograph's":[10],"(HRT)":[11],"Moorfields":[12],"regression":[13],"analysis":[14],"(MRA)":[15],"and":[16,38,46,57,77,84,95,120,129,164,179,216],"glaucoma":[17,37,51,206,215],"probability":[18],"score":[19],"(GPS)":[20],"with":[21,33,53,123,151,170,213,223],"that":[22,190,197,204],"subjective":[24],"grading":[25],"optic":[27,225],"disc":[28,44,93],"photographs":[29,45],"performed":[30],"by":[31,39],"ophthalmologists":[32],"varying":[34],"experience":[35],"ophthalmology":[40],"residents.":[41],"METHODS:":[42],"Digitized":[43],"HRT":[47],"images":[48],"from":[49,134],"97":[50],"patients":[52],"visual":[54,98],"field":[55,99],"defects":[56],"138":[58],"healthy":[59],"individuals":[60],"were":[61,79,88,108,146],"classified":[62,210],"as":[63,110],"either":[64],"within":[65],"normal":[66,73],"limits":[67,74],"(WNL),":[68],"borderline":[69],"(BL),":[70],"or":[71],"outside":[72],"(ONL).":[75],"Sensitivity":[76],"specificity":[78],"compared":[80,122],"for":[81,96,117,136,140,157,160,166,176,184],"MRA,":[82,158,180],"GPS,":[83],"physicians.":[86,185],"Analyses":[87],"also":[89],"made":[90],"according":[91],"to":[92,138,196],"size":[94],"advanced":[97,214],"loss.":[100],"RESULTS:":[101],"Forty-five":[102],"physicians":[103],"participated.":[104],"When":[105],"BL":[106],"results":[107,188],"regarded":[109],"normal,":[111],"sensitivity":[112,154,173,191,220],"was":[113,155,174],"significantly":[114],"higher":[115],"(P<5%)":[116],"both":[118,177],"MRA":[119,137,193,208],"GPS":[121,178],"average":[125,162,200],"physician,":[126,201],"87%,":[127],"79%,":[128],"62%,":[130],"respectively.":[131],"Specificity":[132],"ranged":[133],"86%":[135],"97%":[139],"general":[141],"ophthalmologists,":[142],"but":[143,181,202],"differences":[145],"not":[147,203],"significant.":[148],"In":[149],"eyes":[150,169,212,222],"small":[152,224],"discs,":[153,172],"75%":[156],"60%":[159],"doctor,":[163],"25%":[165],"GPS;":[167],"in":[168,221],"large":[171],"100%":[175],"only":[182],"68%":[183],"CONCLUSION:":[186],"Our":[187],"suggest":[189],"is":[194],"superior":[195],"experts.":[207],"correctly":[209],"all":[211],"showed":[217],"best":[219],"discs.":[226]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":8},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}