{"id":"https://openalex.org/W2001233243","doi":"https://doi.org/10.1136/bmj.2.6093.989","title":"Association of polymyalgia rheumatica and giant-cell arteritis with HLA-B8.","display_name":"Association of polymyalgia rheumatica and giant-cell arteritis with HLA-B8.","publication_year":1977,"publication_date":"1977-10-15","ids":{"openalex":"https://openalex.org/W2001233243","doi":"https://doi.org/10.1136/bmj.2.6093.989","mag":"2001233243","pmid":"https://pubmed.ncbi.nlm.nih.gov/922399","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1631778"},"language":"en","primary_location":{"id":"doi:10.1136/bmj.2.6093.989","doi":"https://doi.org/10.1136/bmj.2.6093.989","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6093.989","pdf_url":"https://www.bmj.com/content/bmj/2/6093/989.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.bmj.com/content/bmj/2/6093/989.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022026729","display_name":"Brian Leslie Hazleman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Hazleman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104206559","display_name":"Anthony H. Goldstone","orcid":"https://orcid.org/0000-0001-8179-7071","observed_orcids":["https://orcid.org/0000-0001-8179-7071"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Goldstone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5076647694","display_name":"Douglas Voak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Voak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.4076,"has_fulltext":true,"cited_by_count":53,"citation_normalized_percentile":{"value":0.97227357,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2","issue":"6093","first_page":"989","last_page":"991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14015","display_name":"Otitis Media and Relapsing Polychondritis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polymyalgia-rheumatica","display_name":"polymyalgia rheumatica","score":0.9980000257492065},{"id":"https://openalex.org/keywords/giant-cell-arteritis","display_name":"giant cell arteritis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/hla-b8","display_name":"HLA-B8","score":1.0},{"id":"https://openalex.org/keywords/hla-a10","display_name":"HLA-A10","score":0.9959999918937683},{"id":"https://openalex.org/keywords/histocompatibility-antigens","display_name":"histocompatibility antigens","score":0.9940000176429749},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7789999842643738},{"id":"https://openalex.org/keywords/immunological-pathogenesis","display_name":"immune pathogenesis","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2780079024","wikidata":"https://www.wikidata.org/wiki/Q1752891","display_name":"Polymyalgia rheumatica","level":5,"score":0.9941077828407288},{"id":"https://openalex.org/C2776712624","wikidata":"https://www.wikidata.org/wiki/Q707816","display_name":"Giant cell arteritis","level":4,"score":0.8365283012390137},{"id":"https://openalex.org/C2781343717","wikidata":"https://www.wikidata.org/wiki/Q1751810","display_name":"Arteritis","level":2,"score":0.7520058155059814},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.638751208782196},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6370790600776672},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.541553258895874},{"id":"https://openalex.org/C202965653","wikidata":"https://www.wikidata.org/wiki/Q2664028","display_name":"Histocompatibility","level":4,"score":0.4732242822647095},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4561043381690979},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.324921190738678},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.29637080430984497},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.25882166624069214},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16969779133796692}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011111","descriptor_name":"Polymyalgia Rheumatica","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D011111","descriptor_name":"Polymyalgia Rheumatica","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011111","descriptor_name":"Polymyalgia Rheumatica","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013700","descriptor_name":"Giant Cell Arteritis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D013700","descriptor_name":"Giant Cell Arteritis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013700","descriptor_name":"Giant Cell Arteritis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1136/bmj.2.6093.989","doi":"https://doi.org/10.1136/bmj.2.6093.989","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6093.989","pdf_url":"https://www.bmj.com/content/bmj/2/6093/989.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},{"id":"pmid:922399","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/922399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British medical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1136/bmj.2.6093.989","doi":"https://doi.org/10.1136/bmj.2.6093.989","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6093.989","pdf_url":"https://www.bmj.com/content/bmj/2/6093/989.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2001233243.pdf","grobid_xml":"https://content.openalex.org/works/W2001233243.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1974647656","https://openalex.org/W1975942514","https://openalex.org/W1986079963","https://openalex.org/W1992125803","https://openalex.org/W1992302056","https://openalex.org/W1996158833","https://openalex.org/W2000156390","https://openalex.org/W2006091964","https://openalex.org/W2022697192","https://openalex.org/W2026424003","https://openalex.org/W2038600815","https://openalex.org/W2039088756","https://openalex.org/W2085282583","https://openalex.org/W2092067487","https://openalex.org/W2092732647","https://openalex.org/W2116599892","https://openalex.org/W2148881578","https://openalex.org/W2242530628","https://openalex.org/W2438373848","https://openalex.org/W2465756547","https://openalex.org/W4213122016","https://openalex.org/W4377099132","https://openalex.org/W6978973585","https://openalex.org/W7124747429"],"related_works":["https://openalex.org/W2418184252","https://openalex.org/W2402832268","https://openalex.org/W9403492","https://openalex.org/W2412698660","https://openalex.org/W2413054598","https://openalex.org/W2031036792","https://openalex.org/W2050257182","https://openalex.org/W2059746731","https://openalex.org/W2404702067","https://openalex.org/W2469779285"],"abstract_inverted_index":{"Histocompatibility":[0],"antigens":[1],"were":[2],"determined":[3],"in":[4,25,36,44],"30":[5],"patients":[6,11,26,48],"with":[7,12,27,49,53,62],"temporal":[8,32],"arteritis,":[9],"27":[10],"polymyalgia":[13,28,50],"rheumatica,":[14],"and":[15,31],"216":[16],"normal":[17],"blood":[18],"donors.":[19],"HLA-B8":[20],"was":[21],"significantly":[22],"more":[23],"common":[24],"rheumatica":[29,51],"(59%)":[30],"arteritis":[33],"(50%)":[34],"than":[35],"the":[37,47,57,63,68],"controls":[38,58],"(27%).":[39],"The":[40],"findings":[41],"of":[42,46,56,67],"HLA-A10":[43],"26%":[45],"compared":[52],"only":[54],"10%":[55],"may":[59],"be":[60],"associated":[61],"suggested":[64],"immunological":[65],"pathogenesis":[66],"condition.":[69]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}