{"id":"https://openalex.org/W2001197917","doi":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","title":"Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial","display_name":"Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial","publication_year":1997,"publication_date":"1997-06-15","ids":{"openalex":"https://openalex.org/W2001197917","doi":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","mag":"2001197917","pmid":"https://pubmed.ncbi.nlm.nih.gov/9189829"},"language":"en","primary_location":{"id":"doi:10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","doi":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","pdf_url":null,"source":{"id":"https://openalex.org/S34814058","display_name":"Journal of Biomedical Materials Research","issn_l":"0021-9304","issn":["0021-9304","1097-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002306237","display_name":"Alonzo D. Cook","orcid":"https://orcid.org/0000-0002-6032-4926","observed_orcids":["https://orcid.org/0000-0002-6032-4926"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alonzo D. Cook","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA","Dept. of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Dept. of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055252245","display_name":"Jeffrey S. Hrkach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey S. Hrkach","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040159886","display_name":"Nicholas N. Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas N. Gao","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042512335","display_name":"Ivette M. Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivette M. Johnson","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013371851","display_name":"Utpal B. Pajvani","orcid":"https://orcid.org/0000-0001-5991-2723","observed_orcids":["https://orcid.org/0000-0001-5991-2723"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Utpal B. Pajvani","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019225871","display_name":"Scott M. Cannizzaro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott M. Cannizzaro","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042597057","display_name":"R\u00f3bert Langer","orcid":"https://orcid.org/0000-0003-4255-0492","observed_orcids":["https://orcid.org/0000-0003-4255-0492","https://orcid.org/0000-0001-5746-9940"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert Langer","raw_affiliation_strings":["Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, E25-342, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042597057"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":8.6798,"has_fulltext":false,"cited_by_count":318,"citation_normalized_percentile":{"value":0.98833139,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"35","issue":"4","first_page":"513","last_page":"523"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.03700000047683716,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rgd-peptide","display_name":"RGD peptide","score":0.9710000157356262},{"id":"https://openalex.org/keywords/bioactive-surface-modification","display_name":"bioactive surface modification","score":0.6740000247955322},{"id":"https://openalex.org/keywords/wettability","display_name":"wettability","score":0.6589999794960022},{"id":"https://openalex.org/keywords/crystallinity","display_name":"crystallinity","score":0.9660000205039978},{"id":"https://openalex.org/keywords/bovine-aortic-endothelial-cells","display_name":"bovine aortic endothelial cells","score":0.9200000166893005},{"id":"https://openalex.org/keywords/cell-spreading","display_name":"cell spreading","score":0.8339999914169312},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.5839999914169312},{"id":"https://openalex.org/keywords/resorbable-biomaterials","display_name":"resorbable biomaterials","score":0.8629999756813049},{"id":"https://openalex.org/keywords/biodegradable-polymers","display_name":"biodegradable polymers","score":0.8640000224113464},{"id":"https://openalex.org/keywords/cell-behavior-control","display_name":"cell behavior control","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C46275449","wikidata":"https://www.wikidata.org/wiki/Q2458815","display_name":"Crystallinity","level":2,"score":0.8630983829498291},{"id":"https://openalex.org/C2778414984","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biomaterial","level":2,"score":0.7128145098686218},{"id":"https://openalex.org/C175708663","wikidata":"https://www.wikidata.org/wiki/Q899559","display_name":"X-ray photoelectron spectroscopy","level":2,"score":0.6562154293060303},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.6500805616378784},{"id":"https://openalex.org/C2776016237","wikidata":"https://www.wikidata.org/wiki/Q178430","display_name":"Lysine","level":3,"score":0.6230548620223999},{"id":"https://openalex.org/C6556556","wikidata":"https://www.wikidata.org/wiki/Q899239","display_name":"Contact angle","level":2,"score":0.5676599740982056},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5584149360656738},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.5542037487030029},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.486884742975235},{"id":"https://openalex.org/C39519442","wikidata":"https://www.wikidata.org/wiki/Q904893","display_name":"Differential scanning calorimetry","level":2,"score":0.45914480090141296},{"id":"https://openalex.org/C134514944","wikidata":"https://www.wikidata.org/wiki/Q817136","display_name":"Wetting","level":2,"score":0.4560357332229614},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.4315830171108246},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3748774230480194},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3660498261451721},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.36484456062316895},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.3513573706150055},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30914121866226196},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.22478601336479187},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.20380297303199768},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10518857836723328},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.061457157135009766},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002152","descriptor_name":"Calorimetry, Differential Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003124","descriptor_name":"Colorimetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011107","descriptor_name":"Polylysine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013052","descriptor_name":"Spectrometry, X-Ray Emission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","doi":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.0.co;2-c","pdf_url":null,"source":{"id":"https://openalex.org/S34814058","display_name":"Journal of Biomedical Materials Research","issn_l":"0021-9304","issn":["0021-9304","1097-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research","raw_type":"journal-article"},{"id":"doi:10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.3.co;2-g","doi":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.3.co;2-g","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1097-4636(19970615)35:4<513::aid-jbm11>3.3.co;2-g","pdf_url":null,"source":{"id":"https://openalex.org/S34814058","display_name":"Journal of Biomedical Materials Research","issn_l":"0021-9304","issn":["0021-9304","1097-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research","raw_type":"journal-article"},{"id":"pmid:9189829","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9189829","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical materials research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2857659594","display_name":"Interdepartmental Biotechnology Training Program","funder_award_id":"T32GM008334","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5109615880","display_name":null,"funder_award_id":"GM08334-06","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1497511230","https://openalex.org/W1522090571","https://openalex.org/W1980745641","https://openalex.org/W1982691790","https://openalex.org/W1983436701","https://openalex.org/W1985909233","https://openalex.org/W1989841409","https://openalex.org/W2000886827","https://openalex.org/W2005821281","https://openalex.org/W2011659304","https://openalex.org/W2018886082","https://openalex.org/W2019205181","https://openalex.org/W2039583786","https://openalex.org/W2045613923","https://openalex.org/W2049224077","https://openalex.org/W2050100752","https://openalex.org/W2062135876","https://openalex.org/W2071453141","https://openalex.org/W2081452775","https://openalex.org/W2083556093","https://openalex.org/W2086970036","https://openalex.org/W2100290924","https://openalex.org/W2131420042","https://openalex.org/W4211147424","https://openalex.org/W4251032101","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1497511230","https://openalex.org/W1992471895","https://openalex.org/W108691190","https://openalex.org/W2358090059","https://openalex.org/W2076174682","https://openalex.org/W2147326507","https://openalex.org/W2381123503","https://openalex.org/W2095429479","https://openalex.org/W2334833945","https://openalex.org/W2365965016"],"abstract_inverted_index":{"The":[0,159,246],"design":[1],"of":[2,13,87,139,148,155,163,185,248,264],"biomaterials":[3],"containing":[4],"specific":[5],"ligands":[6],"on":[7,81,199,226,233,240],"the":[8,11,30,34,48,121,164,183,204,253],"surface":[9,73,82],"offers":[10],"possibility":[12],"creating":[14],"materials":[15,27],"that":[16,33,252],"can":[17],"interact":[18],"with":[19,78,130,201,242],"and":[20,57,72,109,142,157,161,171,177,235,262],"potentially":[21],"control":[22,268],"mammalian":[23],"cell":[24,92,207,269],"behavior.":[25,93],"Biodegradable":[26],"further":[28],"provide":[29],"significant":[31],"advantage":[32],"polymer":[35],"will":[36],"disappear":[37],"in":[38,91],"vivo,":[39],"obviating":[40],"long-term":[41],"negative":[42],"tissue":[43],"responses":[44],"as":[45,47,84,123,150],"well":[46],"need":[49],"for":[50,128,196],"retrieval.":[51],"In":[52,66],"earlier":[53],"studies":[54],"we":[55],"synthesized":[56],"characterized":[58],"arginine-glycine-aspartic":[59],"acid":[60],"(RGD)":[61],"peptide-modified":[62],"poly(lactic":[63,227],"acid-co-lysine)":[64],"(PLAL).":[65],"this":[67,249,265],"study,":[68],"both":[69],"bulk":[70],"properties":[71],"features":[74],"have":[75],"been":[76,260,272],"characterized,":[77],"a":[79,85,124],"focus":[80],"analysis":[83],"means":[86],"interpreting":[88],"observed":[89],"changes":[90],"Bulk":[94],"peptide":[95,122],"attachments":[96],"were":[97,104,115,166,179],"performed":[98],"using":[99,106],"1,1'-carbonyldiimidazole":[100],"(CDI).":[101],"Amino":[102],"groups":[103,141],"measured":[105,116],"colorimetric":[107],"assays":[108],"X-ray":[110],"photoelectron":[111],"spectroscopy":[112],"(XPS).":[113],"Peptides":[114],"by":[117,168,182],"incorporating":[118],"iodine":[119],"into":[120],"distinct":[125],"elemental":[126],"marker":[127],"use":[129,263],"XPS.":[131],"Typical":[132],"samples":[133,165],"contained":[134],"13":[135],"+/-":[136,144,212,217,223,230,237],"4":[137,143,197,231,238],"pmol/cm2":[138],"amino":[140],"0.2":[145],"pmol/":[146],"cm2":[147],"peptides,":[149,203],"calculated":[151],"from":[152,210],"XPS":[153],"measurements":[154],"nitrogen":[156],"iodine.":[158],"wettability":[160],"crystallinity":[162,178],"determined":[167],"contact":[169],"angles":[170],"differential":[172],"scanning":[173],"calorimetry,":[174],"respectively.":[175],"Wettability":[176],"not":[180],"altered":[181],"incorporation":[184],"lysine":[186],"or":[187],"peptides.":[188,245],"After":[189],"incubating":[190],"bovine":[191],"aortic":[192],"endothelial":[193],"(BAE)":[194],"cells":[195],"h":[198],"surfaces":[200,241],"RGD-containing":[202],"mean":[205],"spread":[206],"area":[208],"increased":[209],"77":[211],"2":[213],"microns2":[214,219,225,232,239],"to":[215,221,267],"405":[216],"29":[218],"compared":[220],"116":[222],"11":[224],"acid),":[228],"87":[229],"PLAL,":[234],"105":[236],"RDG-containing":[243],"(control)":[244],"significance":[247],"work":[250],"is":[251],"first":[254],"synthetic":[255],"interactive,":[256],"resorbable":[257],"biomaterial":[258],"has":[259,271],"developed,":[261],"material":[266],"behavior":[270],"demonstrated.":[273]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}