{"id":"https://openalex.org/W2001191000","doi":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","title":"Evidence Supporting the Existence of a Host Cell Surface Receptor for Trypanosoma cruzi1","display_name":"Evidence Supporting the Existence of a Host Cell Surface Receptor for Trypanosoma cruzi1","publication_year":1985,"publication_date":"1985-05-01","ids":{"openalex":"https://openalex.org/W2001191000","doi":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","mag":"2001191000","pmid":"https://pubmed.ncbi.nlm.nih.gov/3891991"},"language":"en","primary_location":{"id":"doi:10.1111/j.1550-7408.1985.tb03070.x","doi":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210213139","display_name":"The Journal of Protozoology","issn_l":"0022-3921","issn":["0022-3921","2375-0804"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Protozoology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013151184","display_name":"FELIPE KIERSZENBAUM","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"FELIPE KIERSZENBAUM","raw_affiliation_strings":["Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan 48824-1 I01"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan 48824-1 I01","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049714185","display_name":"Brad Stiles","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"BRAD STILES","raw_affiliation_strings":["Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan 48824-1 I01"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan 48824-1 I01","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":null,"apc_paid":null,"fwci":1.5821,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.83412738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"2","first_page":"364","last_page":"366"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trypanosoma-cruzi","display_name":"Trypanosoma cruzi","score":1.0},{"id":"https://openalex.org/keywords/host-cell-surface-receptors","display_name":"host cell surface receptors","score":0.9319999814033508},{"id":"https://openalex.org/keywords/trypomastigotes","display_name":"trypomastigotes","score":0.8730000257492065},{"id":"https://openalex.org/keywords/epimastigotes","display_name":"epimastigotes","score":0.9810000061988831},{"id":"https://openalex.org/keywords/parasite-attachment","display_name":"parasite attachment","score":0.41499999165534973},{"id":"https://openalex.org/keywords/flagellates","display_name":"flagellates","score":0.515999972820282},{"id":"https://openalex.org/keywords/chagas-disease","display_name":"Chagas disease","score":0.7289999723434448}],"concepts":[{"id":"https://openalex.org/C2777625466","wikidata":"https://www.wikidata.org/wiki/Q150162","display_name":"Trypanosoma cruzi","level":3,"score":0.8919905424118042},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.6244527697563171},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.5878088474273682},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5775027871131897},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5177668333053589},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5140722990036011},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5126344561576843},{"id":"https://openalex.org/C2778106830","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Cell membrane","level":3,"score":0.43262019753456116},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21144923567771912},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.13535022735595703},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0989561378955841},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006790","descriptor_name":"Host-Parasite Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014349","descriptor_name":"Trypanosoma cruzi","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1550-7408.1985.tb03070.x","doi":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1550-7408.1985.tb03070.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210213139","display_name":"The Journal of Protozoology","issn_l":"0022-3921","issn":["0022-3921","2375-0804"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Protozoology","raw_type":"journal-article"},{"id":"pmid:3891991","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3891991","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of protozoology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1643085250","display_name":"TRYPANOSOMIASIS:  MECHANISMS OF IMMUNITY AND RESISTANCE","funder_award_id":"R01AI014848","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5067571999","display_name":"IMMUNOLOGY OF METACYCLIC TRYPANOSOMA CRUZI","funder_award_id":"R01AI017041","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2164178232","https://openalex.org/W2086328786","https://openalex.org/W2064938432","https://openalex.org/W2146342572","https://openalex.org/W1989429443","https://openalex.org/W2066026173","https://openalex.org/W117796850","https://openalex.org/W2316387079","https://openalex.org/W2035388249","https://openalex.org/W4230981902"],"abstract_inverted_index":{"Membrane":[0],"fragments":[1],"from":[2,22],"trypomastigote":[3],"forms":[4,82],"of":[5,11,40,46,48,60,68,75,83],"Trypanosoma":[6],"cruzi":[7,85],"inhibited":[8],"the":[9,32,38,44,52,58,66,73],"association":[10,47],"intact":[12],"trypomastigotes":[13,29],"with":[14,51],"rat":[15,76],"heart":[16,77],"myoblasts":[17,78],"whereas":[18],"a":[19,69],"similar":[20],"preparation":[21],"non-invasive":[23],"epimastigotes":[24],"did":[25],"not.":[26],"Furthermore,":[27],"killed":[28,49],"bound":[30],"to":[31,79],"host":[33,53],"cell":[34],"surface":[35,74],"and":[36],"prevented":[37],"attachment":[39],"living":[41,61],"organisms.":[42],"Conversely,":[43],"extent":[45],"parasites":[50],"cells":[54],"was":[55],"reduced":[56],"by":[57],"presence":[59,67],"flagellates.":[62],"These":[63],"results":[64],"suggest":[65],"distinct":[70],"structure(s)":[71],"on":[72],"which":[80],"infective":[81],"T.":[84],"can":[86],"bind.":[87]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}