{"id":"https://openalex.org/W2001082811","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","title":"Cortical pyroglutamate amyloid-\u03b2 levels and cognitive decline in Alzheimer's disease","display_name":"Cortical pyroglutamate amyloid-\u03b2 levels and cognitive decline in Alzheimer's disease","publication_year":2014,"publication_date":"2014-06-24","ids":{"openalex":"https://openalex.org/W2001082811","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","mag":"2001082811","pmid":"https://pubmed.ncbi.nlm.nih.gov/25048160","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4268150"},"language":"en","primary_location":{"id":"doi:10.1016/j.neurobiolaging.2014.06.021","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","pdf_url":null,"source":{"id":"https://openalex.org/S284573","display_name":"Neurobiology of Aging","issn_l":"0197-4580","issn":["0197-4580","1558-1497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Aging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4268150","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061837278","display_name":"Violetta N. Pivtoraiko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Violetta N. Pivtoraiko","raw_affiliation_strings":["Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056921315","display_name":"Eric E. Abrahamson","orcid":"https://orcid.org/0000-0003-1787-7581","observed_orcids":["https://orcid.org/0000-0003-1787-7581"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210110523","display_name":"Geriatric Research Education and Clinical Center","ror":"https://ror.org/01nh3sx96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210110523","https://openalex.org/I4210133905","https://openalex.org/I4210147340"]},{"id":"https://openalex.org/I4210133905","display_name":"VA Pittsburgh Healthcare System","ror":"https://ror.org/02qm18h86","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210133905","https://openalex.org/I4210147340"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric E. Abrahamson","raw_affiliation_strings":["Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA","Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA","Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210110523","https://openalex.org/I4210133905"]},{"raw_affiliation_string":"Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I4210110523","https://openalex.org/I4210133905"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070294274","display_name":"Sue E. Leurgans","orcid":"https://orcid.org/0000-0003-2536-1665","observed_orcids":["https://orcid.org/0000-0003-2536-1665"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sue E. Leurgans","raw_affiliation_strings":["Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL"],"raw_orcid":"https://orcid.org/0000-0003-2536-1665","affiliations":[{"raw_affiliation_string":"Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084618289","display_name":"Steven Trent DeKosky","orcid":"https://orcid.org/0000-0003-3743-2758","observed_orcids":["https://orcid.org/0000-0003-3743-2758"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven T. DeKosky","raw_affiliation_strings":["Department of Neurology, University of Virginia School of Medicine, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Virginia School of Medicine, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072527270","display_name":"Elliott Jay Mufson","orcid":"https://orcid.org/0000-0003-4438-7334","observed_orcids":["https://orcid.org/0000-0003-4438-7334"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elliott J. Mufson","raw_affiliation_strings":["Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021171640","display_name":"Milo\u0161 D. Ikonomovi\u0107","orcid":"https://orcid.org/0000-0002-8745-3293","observed_orcids":["https://orcid.org/0000-0002-8745-3293"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210110523","display_name":"Geriatric Research Education and Clinical Center","ror":"https://ror.org/01nh3sx96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210110523","https://openalex.org/I4210133905","https://openalex.org/I4210147340"]},{"id":"https://openalex.org/I4210133905","display_name":"VA Pittsburgh Healthcare System","ror":"https://ror.org/02qm18h86","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210133905","https://openalex.org/I4210147340"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Milos D. Ikonomovic","raw_affiliation_strings":["Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ikonomovicmd@upmc.edu","Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA","Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA","Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ikonomovicmd@upmc.edu","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210110523","https://openalex.org/I4210133905"]},{"raw_affiliation_string":"Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I4210110523","https://openalex.org/I4210133905"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5021171640"],"corresponding_institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210110523","https://openalex.org/I4210133905"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":null,"fwci":2.0759,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.85381754,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"36","issue":"1","first_page":"12","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pyroglutamate-amyloid-beta","display_name":"pyroglutamate amyloid-beta","score":0.9079999923706055},{"id":"https://openalex.org/keywords/amyloid-beta-1-42","display_name":"amyloid-beta 42","score":0.7630000114440918},{"id":"https://openalex.org/keywords/amyloid-beta1-40","display_name":"amyloid-\u03b21-40","score":0.9850000143051147},{"id":"https://openalex.org/keywords/posterior-cingulate-cortex","display_name":"posterior cingulate cortex","score":0.9739999771118164},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9610000252723694},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.9509999752044678},{"id":"https://openalex.org/keywords/episodic-memory","display_name":"episodic memory","score":0.8119999766349792},{"id":"https://openalex.org/keywords/amyloid-plaques","display_name":"amyloid plaques","score":0.7580000162124634},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.8460000157356262},{"id":"https://openalex.org/keywords/mini-mental-state-examination","display_name":"Mini-Mental State Examination","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C2780130745","wikidata":"https://www.wikidata.org/wiki/Q1650750","display_name":"Neuropathology","level":3,"score":0.8129170536994934},{"id":"https://openalex.org/C2778733324","wikidata":"https://www.wikidata.org/wiki/Q2998088","display_name":"Posterior cingulate","level":3,"score":0.6882249116897583},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.6441789865493774},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.6371645927429199},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.5410998463630676},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5001354217529297},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.4946267306804657},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.46747586131095886},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.4463391602039337},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3940718173980713},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.38992124795913696},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3876165449619293},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3474668264389038},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.27742618322372437}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006179","descriptor_name":"Gyrus Cinguli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011761","descriptor_name":"Pyrrolidonecarboxylic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neurobiolaging.2014.06.021","doi":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neurobiolaging.2014.06.021","pdf_url":null,"source":{"id":"https://openalex.org/S284573","display_name":"Neurobiology of Aging","issn_l":"0197-4580","issn":["0197-4580","1558-1497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of Aging","raw_type":"journal-article"},{"id":"pmid:25048160","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25048160","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurobiology of aging","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4268150","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4268150","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurobiol Aging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4268150","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4268150","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurobiol Aging","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.979200005531311,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2112592252","display_name":"The role of astrogliosis in aging and the pathological and clinical progression of Alzheimer's Disease","funder_award_id":"P01AG025204","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2278325105","display_name":null,"funder_award_id":"PO1AG025204","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G3711302076","display_name":"Neurobiology of Mild Cognitive Impairment in the Elderly","funder_award_id":"P01AG014449","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5029820101","display_name":"Rush Alzheimer's Disease Core Center","funder_award_id":"P30AG010161","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6770541748","display_name":"Cellular and Molecular Medial Temporal Lobe Pathology in Elderly PreMCI subjects","funder_award_id":"R01AG043375","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8772975020","display_name":null,"funder_award_id":"RO1AG043375","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8809299042","display_name":null,"funder_award_id":"PO1AG014449","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320310664","display_name":"Rush University","ror":"https://ror.org/01k9xac83"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W38490725","https://openalex.org/W1520627922","https://openalex.org/W1552912270","https://openalex.org/W1618236677","https://openalex.org/W1733175660","https://openalex.org/W1847168837","https://openalex.org/W1972153963","https://openalex.org/W1973621050","https://openalex.org/W1975578749","https://openalex.org/W1979590047","https://openalex.org/W1979818695","https://openalex.org/W1987365479","https://openalex.org/W1991435932","https://openalex.org/W1997301424","https://openalex.org/W1999017783","https://openalex.org/W2000706612","https://openalex.org/W2003109983","https://openalex.org/W2006858320","https://openalex.org/W2007389732","https://openalex.org/W2008854521","https://openalex.org/W2009733405","https://openalex.org/W2017898906","https://openalex.org/W2021653459","https://openalex.org/W2024656644","https://openalex.org/W2024866120","https://openalex.org/W2025561374","https://openalex.org/W2027693753","https://openalex.org/W2028050242","https://openalex.org/W2028379029","https://openalex.org/W2030260517","https://openalex.org/W2045197448","https://openalex.org/W2046847750","https://openalex.org/W2052742260","https://openalex.org/W2061216396","https://openalex.org/W2066093836","https://openalex.org/W2070071706","https://openalex.org/W2070137740","https://openalex.org/W2071310220","https://openalex.org/W2075348467","https://openalex.org/W2075464796","https://openalex.org/W2079082269","https://openalex.org/W2080592458","https://openalex.org/W2080705044","https://openalex.org/W2088151512","https://openalex.org/W2091874081","https://openalex.org/W2100610042","https://openalex.org/W2112232230","https://openalex.org/W2113518834","https://openalex.org/W2113759533","https://openalex.org/W2128228199","https://openalex.org/W2133019124","https://openalex.org/W2134836371","https://openalex.org/W2143461767","https://openalex.org/W2144098186","https://openalex.org/W2144631174","https://openalex.org/W2146729934","https://openalex.org/W2148080316","https://openalex.org/W2156981442","https://openalex.org/W2162124438","https://openalex.org/W2167311298","https://openalex.org/W2167720733","https://openalex.org/W2399749275","https://openalex.org/W2725718031","https://openalex.org/W6631084178"],"related_works":["https://openalex.org/W2532716004","https://openalex.org/W2804337526","https://openalex.org/W2981293780","https://openalex.org/W1552912270","https://openalex.org/W2050079586","https://openalex.org/W2462898031","https://openalex.org/W2142950794","https://openalex.org/W2533459023","https://openalex.org/W2932040131","https://openalex.org/W2027693753"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}