{"id":"https://openalex.org/W2000985479","doi":"https://doi.org/10.1136/bmj.2.6194.833","title":"Sialochemistry in evaluating bromhexine treatment of Sj\u00f6gren's syndrome.","display_name":"Sialochemistry in evaluating bromhexine treatment of Sj\u00f6gren's syndrome.","publication_year":1979,"publication_date":"1979-10-06","ids":{"openalex":"https://openalex.org/W2000985479","doi":"https://doi.org/10.1136/bmj.2.6194.833","mag":"2000985479","pmid":"https://pubmed.ncbi.nlm.nih.gov/509119","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1596674"},"language":"en","primary_location":{"id":"doi:10.1136/bmj.2.6194.833","doi":"https://doi.org/10.1136/bmj.2.6194.833","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6194.833","pdf_url":"https://www.bmj.com/content/bmj/2/6194/833.1.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.bmj.com/content/bmj/2/6194/833.1.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111908555","display_name":"A. M. Nahir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A M Nahir","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112142262","display_name":"Hanna Ben\u2010Aryeh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H B Aryeh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060667752","display_name":"Raymonde Szargel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R Szargel","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064429330","display_name":"Yehuda Scharf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Y Scharf","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007935935","display_name":"D. Gutman","orcid":"https://orcid.org/0000-0002-6955-0663","observed_orcids":["https://orcid.org/0000-0002-6955-0663"]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D Gutman","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042056860","display_name":"Y Blaustein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Y Blaustein","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064429330","display_name":"Yehuda Scharf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799342194","display_name":"Royal Derby Hospital","ror":"https://ror.org/005r9p256","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799342194","https://openalex.org/I4210149821"]},{"id":"https://openalex.org/I2802921333","display_name":"Nottingham City Hospital","ror":"https://ror.org/0022b3c04","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I2802921333"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Y Scharf","raw_affiliation_strings":[", Department of Microbiology, Uni-versity Hospital, Nottingham","Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","Microbiology, Derbyshire Royal Infirmary,","Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":", Department of Microbiology, Uni-versity Hospital, Nottingham","institution_ids":[]},{"raw_affiliation_string":"Department of Medicine, Leicester University; and Dr D C Banks, City Hospital, Nottingham, for referring cases 1,","institution_ids":["https://openalex.org/I2802921333"]},{"raw_affiliation_string":"Microbiology, Derbyshire Royal Infirmary,","institution_ids":["https://openalex.org/I2799342194"]},{"raw_affiliation_string":"Regional Department of Neurology and Neurosurgery, Derbyshire Royal Infirmary, Derby DE1 2QY","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7337,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.89976636,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"6194","first_page":"833.1","last_page":"833"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11035","display_name":"Salivary Gland Tumors Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sialochemistry","display_name":"sialochemistry","score":0.8519999980926514},{"id":"https://openalex.org/keywords/bromhexine","display_name":"bromhexine","score":0.9490000009536743},{"id":"https://openalex.org/keywords/sjogren-s-syndrome","display_name":"Sj\u00f6gren's syndrome","score":0.9940000176429749},{"id":"https://openalex.org/keywords/sialometry","display_name":"sialometry","score":0.6460000276565552},{"id":"https://openalex.org/keywords/salivary-gland-function","display_name":"salivary gland function","score":0.6129999756813049},{"id":"https://openalex.org/keywords/treatment-evaluation","display_name":"treatment evaluation","score":0.5249999761581421}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5706811547279358},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.5626867413520813},{"id":"https://openalex.org/C2777706064","wikidata":"https://www.wikidata.org/wiki/Q335555","display_name":"Sj\u00f6gren syndrome","level":4,"score":0.44213730096817017},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25531429052352905},{"id":"https://openalex.org/C2778674544","wikidata":"https://www.wikidata.org/wiki/Q1414805","display_name":"Systemic disease","level":3,"score":0.05753257870674133},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.05117374658584595}],"mesh":[{"descriptor_ui":"D001964","descriptor_name":"Bromhexine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001964","descriptor_name":"Bromhexine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1136/bmj.2.6194.833","doi":"https://doi.org/10.1136/bmj.2.6194.833","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6194.833","pdf_url":"https://www.bmj.com/content/bmj/2/6194/833.1.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},{"id":"pmid:509119","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/509119","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British medical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1136/bmj.2.6194.833","doi":"https://doi.org/10.1136/bmj.2.6194.833","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.2.6194.833","pdf_url":"https://www.bmj.com/content/bmj/2/6194/833.1.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000985479.pdf","grobid_xml":"https://content.openalex.org/works/W2000985479.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W2094490101","https://openalex.org/W2434347936","https://openalex.org/W2463404233"],"related_works":["https://openalex.org/W1982438781","https://openalex.org/W2400247721","https://openalex.org/W2417557751","https://openalex.org/W3191846339","https://openalex.org/W2291454799","https://openalex.org/W2417821999","https://openalex.org/W2094490101","https://openalex.org/W2006364644","https://openalex.org/W2404040223","https://openalex.org/W2318068793"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}