{"id":"https://openalex.org/W2000924219","doi":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","title":"Dinuclear copper(II) complexes containing 6-(benzylamino)purines as bridging ligands: Synthesis, characterization, and in vitro and in vivo antioxidant activities","display_name":"Dinuclear copper(II) complexes containing 6-(benzylamino)purines as bridging ligands: Synthesis, characterization, and in vitro and in vivo antioxidant activities","publication_year":2008,"publication_date":"2008-12-28","ids":{"openalex":"https://openalex.org/W2000924219","doi":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","mag":"2000924219","pmid":"https://pubmed.ncbi.nlm.nih.gov/19171383"},"language":"en","primary_location":{"id":"doi:10.1016/j.jinorgbio.2008.12.009","doi":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S155362585","display_name":"Journal of Inorganic Biochemistry","issn_l":"0162-0134","issn":["0162-0134","1873-3344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inorganic Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006285994","display_name":"Pavel \u0160tarha","orcid":"https://orcid.org/0000-0003-0422-045X","observed_orcids":["https://orcid.org/0000-0003-0422-045X"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Pavel \u0160tarha","raw_affiliation_strings":["Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, Kr\u00edzkovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, Kr\u00edzkovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]},{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020987694","display_name":"Zden\u011bk Tr\u00e1vn\u00ed\u010dek","orcid":"https://orcid.org/0000-0002-5890-7874","observed_orcids":["https://orcid.org/0000-0002-5890-7874"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":true,"raw_author_name":"Zden\u011bk Tr\u00e1vn\u00ed\u010dek","raw_affiliation_strings":["Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066415290","display_name":"Radovan Herchel","orcid":"https://orcid.org/0000-0001-8262-4666","observed_orcids":["https://orcid.org/0000-0001-8262-4666"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Radovan Herchel","raw_affiliation_strings":["Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014591308","display_name":"Igor Popa","orcid":"https://orcid.org/0000-0003-3598-6597","observed_orcids":["https://orcid.org/0000-0003-3598-6597"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Igor Popa","raw_affiliation_strings":["Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077270842","display_name":"Pavel Such\u00fd","orcid":"https://orcid.org/0000-0002-6277-2749","observed_orcids":["https://orcid.org/0000-0002-6277-2749"]},"institutions":[{"id":"https://openalex.org/I113254221","display_name":"University of Veterinary Sciences Brno","ror":"https://ror.org/04rk6w354","country_code":"CZ","type":"education","lineage":["https://openalex.org/I113254221"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Pavel Such\u00fd","raw_affiliation_strings":["Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palack\u00e9ho 1\u20133, CZ-612 42 Brno, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Pharmacology and Toxicology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palack\u00e9ho 1\u20133, CZ-612 42 Brno, Czech Republic","institution_ids":["https://openalex.org/I113254221"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030509228","display_name":"J\u00e1n Van\u010do","orcid":"https://orcid.org/0000-0003-3351-1192","observed_orcids":["https://orcid.org/0000-0003-3351-1192"]},"institutions":[{"id":"https://openalex.org/I113254221","display_name":"University of Veterinary Sciences Brno","ror":"https://ror.org/04rk6w354","country_code":"CZ","type":"education","lineage":["https://openalex.org/I113254221"]},{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"J\u00e1n Van\u010do","raw_affiliation_strings":["Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palack\u00e9ho 1\u20133, CZ-612 42 Brno, Czech Republic","Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palack\u00e9ho 1\u20133, CZ-612 42 Brno, Czech Republic","institution_ids":["https://openalex.org/I113254221"]},{"raw_affiliation_string":"Department of Inorganic Chemistry, Faculty of Science, Palack\u00fd University, K\u0159\u00ed\u017ekovsk\u00e9ho 10, CZ-771 47 Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020987694"],"corresponding_institution_ids":["https://openalex.org/I70703428"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":4.0511,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.94158741,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"103","issue":"3","first_page":"432","last_page":"440"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11746","display_name":"Inorganic and Organometallic Chemistry","score":0.012400000356137753,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dinuclear-copper-ii-complex","display_name":"dinuclear copper(II) complex","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bridging-ligands","display_name":"bridging ligands","score":0.9700000286102295},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/superoxide-dismutase-mimics","display_name":"superoxide dismutase mimetic","score":0.8209999799728394},{"id":"https://openalex.org/keywords/alloxan-induced-diabetes","display_name":"alloxan-induced diabetes","score":0.9279999732971191},{"id":"https://openalex.org/keywords/cytoprotection","display_name":"cytoprotection","score":0.8399999737739563},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.7699999809265137},{"id":"https://openalex.org/keywords/coordination-chemistry","display_name":"coordination chemistry","score":0.4129999876022339},{"id":"https://openalex.org/keywords/magnetic-susceptibility","display_name":"magnetic susceptibility","score":0.5149999856948853},{"id":"https://openalex.org/keywords/electron-spin-resonance","display_name":"electron spin resonance","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9027139544487},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7260763645172119},{"id":"https://openalex.org/C2776476023","wikidata":"https://www.wikidata.org/wiki/Q188261","display_name":"Purine","level":3,"score":0.6572239398956299},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6399641633033752},{"id":"https://openalex.org/C2781005915","wikidata":"https://www.wikidata.org/wiki/Q417701","display_name":"Alloxan","level":3,"score":0.5717819929122925},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.5456867218017578},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5233147144317627},{"id":"https://openalex.org/C187961010","wikidata":"https://www.wikidata.org/wiki/Q260463","display_name":"Electron paramagnetic resonance","level":2,"score":0.5028600096702576},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.4832044839859009},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4307124614715576},{"id":"https://openalex.org/C169586020","wikidata":"https://www.wikidata.org/wiki/Q3780159","display_name":"Purine metabolism","level":3,"score":0.4140390455722809},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.32771557569503784},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32482701539993286},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.1759718954563141},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0752270519733429},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.05385461449623108},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001593","descriptor_name":"Benzyl Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003300","descriptor_name":"Copper","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007701","descriptor_name":"Kinetin","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D007701","descriptor_name":"Kinetin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007701","descriptor_name":"Kinetin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011687","descriptor_name":"Purines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019610","descriptor_name":"Cytoprotection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jinorgbio.2008.12.009","doi":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jinorgbio.2008.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S155362585","display_name":"Journal of Inorganic Biochemistry","issn_l":"0162-0134","issn":["0162-0134","1873-3344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inorganic Biochemistry","raw_type":"journal-article"},{"id":"pmid:19171383","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19171383","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of inorganic biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1145693896","display_name":null,"funder_award_id":"MSM 6198959218","funder_id":"https://openalex.org/F4320321005","funder_display_name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy"}],"funders":[{"id":"https://openalex.org/F4320321005","display_name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","ror":"https://ror.org/037n8p820"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W49344967","https://openalex.org/W603049740","https://openalex.org/W629312534","https://openalex.org/W1487348743","https://openalex.org/W1511453743","https://openalex.org/W1940436875","https://openalex.org/W1966040658","https://openalex.org/W1984781269","https://openalex.org/W1991047265","https://openalex.org/W1992040740","https://openalex.org/W1992509138","https://openalex.org/W1997368175","https://openalex.org/W1998722626","https://openalex.org/W1999414487","https://openalex.org/W2002082805","https://openalex.org/W2019456920","https://openalex.org/W2026010825","https://openalex.org/W2031034919","https://openalex.org/W2044290155","https://openalex.org/W2052994316","https://openalex.org/W2053516112","https://openalex.org/W2069533858","https://openalex.org/W2078065145","https://openalex.org/W2093220503","https://openalex.org/W2104428868","https://openalex.org/W2105249240","https://openalex.org/W2135129680","https://openalex.org/W2146051607","https://openalex.org/W2148616203","https://openalex.org/W2487770617","https://openalex.org/W3138733034","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1973037777","https://openalex.org/W2056341906","https://openalex.org/W2019978452","https://openalex.org/W2536743639","https://openalex.org/W1965706097","https://openalex.org/W2990386404","https://openalex.org/W2050485422","https://openalex.org/W4212980446","https://openalex.org/W1965717731","https://openalex.org/W1983986347"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}