{"id":"https://openalex.org/W2000866074","doi":"https://doi.org/10.1515/cclm.2003.052","title":"National External Quality Assessment Scheme for Lymphocyte Immunophenotyping in Belgium","display_name":"National External Quality Assessment Scheme for Lymphocyte Immunophenotyping in Belgium","publication_year":2003,"publication_date":"2003-01-24","ids":{"openalex":"https://openalex.org/W2000866074","doi":"https://doi.org/10.1515/cclm.2003.052","mag":"2000866074","pmid":"https://pubmed.ncbi.nlm.nih.gov/12705342"},"language":"en","primary_location":{"id":"doi:10.1515/cclm.2003.052","doi":"https://doi.org/10.1515/cclm.2003.052","is_oa":false,"landing_page_url":"https://doi.org/10.1515/cclm.2003.052","pdf_url":null,"source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020990615","display_name":"Marjan Van Blerk","orcid":"https://orcid.org/0000-0002-2238-3773","observed_orcids":["https://orcid.org/0000-0002-2238-3773"]},"institutions":[{"id":"https://openalex.org/I4210158280","display_name":"Institut Scientifique de Sant\u00e9 Publique","ror":"https://ror.org/04ws26165","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210158280"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marjan Van Blerk","raw_affiliation_strings":["Department of Clinical Biology, Scientific Institute of Public Health, Brussels, Belgium. m.vanblerk@iph.fgov.be","Department of Clinical Biology, Scientific Institute of Public Health, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Biology, Scientific Institute of Public Health, Brussels, Belgium. m.vanblerk@iph.fgov.be","institution_ids":["https://openalex.org/I4210158280"]},{"raw_affiliation_string":"Department of Clinical Biology, Scientific Institute of Public Health, Brussels, Belgium","institution_ids":["https://openalex.org/I4210158280"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michel Bernier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michel Bernier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071488467","display_name":"Xavier Bossuyt","orcid":"https://orcid.org/0000-0001-6856-8485","observed_orcids":["https://orcid.org/0000-0001-6856-8485"]},"institutions":[{"id":"https://openalex.org/I2800231306","display_name":"Universitair Ziekenhuis Leuven","ror":"https://ror.org/0424bsv16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2800231306"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Xavier Bossuyt","raw_affiliation_strings":["Universitair Ziekenhuis Leuven"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitair Ziekenhuis Leuven","institution_ids":["https://openalex.org/I2800231306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109892826","display_name":"Bernard Ch\u00e2telain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bernard Chatelain","raw_affiliation_strings":["Universite Catholique de Louvain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universite Catholique de Louvain","institution_ids":["https://openalex.org/I95674353","https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071459380","display_name":"Jean\u2010Luc D'hautcourt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-Luc D'Hautcourt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108416317","display_name":"Christian J. Demanet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Demanet","raw_affiliation_strings":["Immunology and Microbiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology and Microbiology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083521306","display_name":"Luc Kestens","orcid":"https://orcid.org/0000-0001-9374-1921","observed_orcids":["https://orcid.org/0000-0001-9374-1921"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luc Kestens","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111534546","display_name":"Dirk R. Van Bockstaele","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dirk Van Bockstaele","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048284744","display_name":"Tania Crucitti","orcid":"https://orcid.org/0000-0002-2235-6038","observed_orcids":["https://orcid.org/0000-0002-2235-6038"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tania Crucitti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109047873","display_name":"Jean-Claude Libeer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158280","display_name":"Institut Scientifique de Sant\u00e9 Publique","ror":"https://ror.org/04ws26165","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210158280"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jean-Claude Libeer","raw_affiliation_strings":["Scientific Institute of Public Health, Brussels"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Institute of Public Health, Brussels","institution_ids":["https://openalex.org/I4210158280"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":null,"fwci":0.547,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.66520719,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"41","issue":"3","first_page":"323","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13309","display_name":"Reliability and Agreement in Measurement","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12871","display_name":"Healthcare Quality and Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lymphocyte-immunophenotyping","display_name":"lymphocyte phenotyping","score":0.9440000057220459},{"id":"https://openalex.org/keywords/external-quality-assessment","display_name":"external quality assessment","score":0.9829999804496765},{"id":"https://openalex.org/keywords/interlaboratory-variability","display_name":"inter-laboratory variability","score":0.8989999890327454},{"id":"https://openalex.org/keywords/intra-laboratory-variability","display_name":"intra-laboratory variability","score":0.859000027179718},{"id":"https://openalex.org/keywords/cd3-t-cells","display_name":"CD3+ T cells","score":0.7139999866485596},{"id":"https://openalex.org/keywords/cd4-cells","display_name":"CD4 cells","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":1.0},{"id":"https://openalex.org/keywords/cd19-b-cells","display_name":"CD19+ B cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/white-blood-cell-count","display_name":"white blood cell count","score":0.734000027179718},{"id":"https://openalex.org/keywords/laboratory-performance-improvement","display_name":"laboratory performance improvement","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C196166836","wikidata":"https://www.wikidata.org/wiki/Q902926","display_name":"Immunophenotyping","level":3,"score":0.7857906818389893},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5645779371261597},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.5575705170631409},{"id":"https://openalex.org/C2778957590","wikidata":"https://www.wikidata.org/wiki/Q798033","display_name":"CD19","level":3,"score":0.5390796661376953},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.5189495086669922},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40077388286590576},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3657376170158386},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3548838198184967},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3326253592967987},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3259463906288147},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32204294204711914},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.25900501012802124},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1410423219203949}],"mesh":[{"descriptor_ui":"D001772","descriptor_name":"Blood Cell Count","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D003625","descriptor_name":"Data Collection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005069","descriptor_name":"Evaluation Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007753","descriptor_name":"Laboratories","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015448","descriptor_name":"Leukemia, B-Cell","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1515/cclm.2003.052","doi":"https://doi.org/10.1515/cclm.2003.052","is_oa":false,"landing_page_url":"https://doi.org/10.1515/cclm.2003.052","pdf_url":null,"source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine","raw_type":"journal-article"},{"id":"pmid:12705342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12705342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical chemistry and laboratory medicine","raw_type":"Journal Article"},{"id":"pmh:oai:dial.uclouvain.be:boreal:236876","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2078.1/236876","pdf_url":null,"source":{"id":"https://openalex.org/S4306401974","display_name":"DIAL (Catholic University of Leuven)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I99464096","host_organization_name":"KU Leuven","host_organization_lineage":["https://openalex.org/I99464096"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Chemistry and Laboratory Medicine : Associated with FESCC and IFCC, Vol. 41, no.3, p. 323-330 (2003)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:50138","doi":null,"is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/national-external-quality-assessment-scheme-for-lymphocyte-immunophenotyping-in-belgium(4ecd9eb0-29b9-4165-b6a1-ac50e8289156).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1214817017","https://openalex.org/W1480851099","https://openalex.org/W1971233696","https://openalex.org/W1994159439","https://openalex.org/W1994898044","https://openalex.org/W2005670282","https://openalex.org/W2014961664","https://openalex.org/W2025485262","https://openalex.org/W2027411352","https://openalex.org/W2029108323","https://openalex.org/W2031495190","https://openalex.org/W2051959280","https://openalex.org/W2054304440","https://openalex.org/W2061296252","https://openalex.org/W2067418606","https://openalex.org/W2071387603","https://openalex.org/W2076984831","https://openalex.org/W2098179949"],"related_works":["https://openalex.org/W2031495190","https://openalex.org/W2379152053","https://openalex.org/W2084908100","https://openalex.org/W1927139887","https://openalex.org/W2905272057","https://openalex.org/W1575730106","https://openalex.org/W2061296252","https://openalex.org/W1966824809","https://openalex.org/W2000912207","https://openalex.org/W2039327216"],"abstract_inverted_index":{"In":[0],"2000,":[1],"the":[2,25,119,150,172],"Belgian":[3],"Scientific":[4],"Institute":[5],"of":[6,24,31,59,66,76,116,137,152,160,181],"Public":[7],"Health":[8],"introduced":[9],"a":[10],"voluntary":[11],"external":[12],"quality":[13],"assessment":[14],"scheme":[15],"for":[16,47,84,100,110,118,127,132],"lymphocyte":[17],"immunophenotyping.":[18],"This":[19],"paper":[20],"provides":[21],"an":[22],"analysis":[23],"first":[26],"six":[27],"surveys.":[28],"Specimens":[29],"consisted":[30],"fresh":[32],"EDTA-anticoagulated":[33],"whole":[34],"blood":[35,55],"and":[36,49,61,63,70,82,88,102,106,139,155,165],"were":[37,45,50,78,122],"sent":[38],"by":[39,169],"overnight":[40],"mail.":[41],"The":[42,135,158],"41":[43],"participants":[44],"surveyed":[46],"methodology":[48],"asked":[51],"to":[52,130],"report":[53],"white":[54],"cell":[56,90,104,112],"count,":[57],"percentage":[58,136,151],"lymphocytes,":[60],"percentages":[62],"absolute":[64,120],"numbers":[65],"CD3+,":[67,85],"CD4+,":[68,86],"CD8+,":[69,87],"CD19+":[71,89,133],"cells.":[72,134,157],"Median":[73,114],"intralaboratory":[74],"coefficients":[75,115],"variation":[77,117],"1.0,":[79],"1.3,":[80],"1.7,":[81],"3.2%":[83],"percentages,":[91,105],"respectively.":[92],"Interlaboratory":[93],"variability":[94,175],"was":[95,143],"consistently":[96],"lower":[97,107,148],"than":[98,108,149],"6.5%":[99],"CD3+":[101,141],"CD4+CD3+":[103,128,138],"9.5%":[109],"CD8+CD3+":[111],"percentages.":[113],"values":[121],"higher,":[123],"ranging":[124],"from":[125],"10.1%":[126],"cells":[129,142,167],"16.5%":[131],"CD8+":[140,156,166],"in":[144],"several":[145],"samples":[146],"significantly":[147],"total":[153,163],"CD4+":[154,164],"number":[159],"laboratories":[161,188],"measuring":[162],"decreased":[168],"30%":[170],"during":[171],"programme.":[173],"Between-laboratory":[174],"remained":[176],"stable":[177],"over":[178],"time.":[179],"Analysis":[180],"individual":[182],"laboratory":[183],"performance":[184],"indicated":[185],"that":[186],"some":[187],"markedly":[189],"improved":[190],"their":[191],"results.":[192]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}