{"id":"https://openalex.org/W2000856254","doi":"https://doi.org/10.1016/0049-3848(84)90383-9","title":"Antithrombic properties of insoluble modified polystyrene : Part I","display_name":"Antithrombic properties of insoluble modified polystyrene : Part I","publication_year":1984,"publication_date":"1984-05-01","ids":{"openalex":"https://openalex.org/W2000856254","doi":"https://doi.org/10.1016/0049-3848(84)90383-9","mag":"2000856254","pmid":"https://pubmed.ncbi.nlm.nih.gov/6740563"},"language":"en","primary_location":{"id":"doi:10.1016/0049-3848(84)90383-9","doi":"https://doi.org/10.1016/0049-3848(84)90383-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0049-3848(84)90383-9","pdf_url":null,"source":{"id":"https://openalex.org/S134546602","display_name":"Thrombosis Research","issn_l":"0049-3848","issn":["0049-3848","1879-2472"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049256426","display_name":"Catherine Boisson\u2010Vidal","orcid":"https://orcid.org/0000-0001-6651-4926","observed_orcids":["https://orcid.org/0000-0001-6651-4926"]},"institutions":[{"id":"https://openalex.org/I4210091279","display_name":"Universit\u00e9 Sorbonne Paris Nord","ror":"https://ror.org/0199hds37","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210091279"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Boisson","raw_affiliation_strings":["Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France","institution_ids":["https://openalex.org/I4210091279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113523852","display_name":"Dani\u00e8le Gulino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091279","display_name":"Universit\u00e9 Sorbonne Paris Nord","ror":"https://ror.org/0199hds37","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210091279"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D. Gulino","raw_affiliation_strings":["Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France","institution_ids":["https://openalex.org/I4210091279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043813199","display_name":"J. Jozefonvicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091279","display_name":"Universit\u00e9 Sorbonne Paris Nord","ror":"https://ror.org/0199hds37","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210091279"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Jozefonvicz","raw_affiliation_strings":["Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherches sur les Macromol\u00e9cules, G.R.E.C.O 130048, C.S.P. Universit\u00e9 PARIS-NORD Avenue J.B. Clement 93430 Villetaneuse, France","institution_ids":["https://openalex.org/I4210091279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103576946","display_name":"Anne\u2010Marie Fischer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A.M. Fischer","raw_affiliation_strings":["D\u00e9partement d'h\u00e9matologie, G.R.E.C.O. 130048, C.H.U. Necker-Enfants-Malades 156 rue de Vaugirard, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement d'h\u00e9matologie, G.R.E.C.O. 130048, C.H.U. Necker-Enfants-Malades 156 rue de Vaugirard, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210086369"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111720639","display_name":"Jacqueline Tapon\u2010Bretaudi\u00e8re","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J Tapon-Bretaudiere","raw_affiliation_strings":["D\u00e9partement d'h\u00e9matologie, G.R.E.C.O. 130048, C.H.U. Necker-Enfants-Malades 156 rue de Vaugirard, 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement d'h\u00e9matologie, G.R.E.C.O. 130048, C.H.U. Necker-Enfants-Malades 156 rue de Vaugirard, 75015 Paris, France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210086369"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4080,"currency":"USD","value_usd":4080},"apc_paid":null,"fwci":1.9533,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.8570706,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"34","issue":"4","first_page":"269","last_page":"276"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.8314999938011169,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.8314999938011169,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.1492999941110611,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thrombin-binding","display_name":"thrombin binding","score":0.5809999704360962},{"id":"https://openalex.org/keywords/thrombin-time","display_name":"thrombin time","score":0.7799999713897705},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.8240000009536743},{"id":"https://openalex.org/keywords/antithrombin-iii","display_name":"antithrombin III","score":0.8899999856948853},{"id":"https://openalex.org/keywords/affinity-constant","display_name":"affinity constant","score":0.777999997138977},{"id":"https://openalex.org/keywords/ionic-strength","display_name":"ionic strength","score":0.593999981880188},{"id":"https://openalex.org/keywords/insoluble-polymers","display_name":"insoluble polymers","score":0.6200000047683716}],"concepts":[{"id":"https://openalex.org/C2777292125","wikidata":"https://www.wikidata.org/wiki/Q409166","display_name":"Thrombin","level":3,"score":0.8897914290428162},{"id":"https://openalex.org/C2779026020","wikidata":"https://www.wikidata.org/wiki/Q416336","display_name":"Antithrombin","level":3,"score":0.7464860081672668},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7087699770927429},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.6998426914215088},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.5926967263221741},{"id":"https://openalex.org/C2777922577","wikidata":"https://www.wikidata.org/wiki/Q146243","display_name":"Polystyrene","level":3,"score":0.5739883780479431},{"id":"https://openalex.org/C187428577","wikidata":"https://www.wikidata.org/wiki/Q898396","display_name":"Ionic strength","level":3,"score":0.5441722273826599},{"id":"https://openalex.org/C2780077467","wikidata":"https://www.wikidata.org/wiki/Q2520736","display_name":"Thrombin time","level":4,"score":0.5196115374565125},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.4910316467285156},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.45526695251464844},{"id":"https://openalex.org/C77171857","wikidata":"https://www.wikidata.org/wiki/Q5135593","display_name":"Clotting time","level":3,"score":0.4204062521457672},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3712112307548523},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20092475414276123},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19375479221343994},{"id":"https://openalex.org/C2778261982","wikidata":"https://www.wikidata.org/wiki/Q1755136","display_name":"Partial thromboplastin time","level":3,"score":0.18613967299461365},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.1510295271873474},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.12053078413009644},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.06249719858169556},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000042","descriptor_name":"Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000990","descriptor_name":"Antithrombin III","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001780","descriptor_name":"Blood Coagulation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011137","descriptor_name":"Polystyrenes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012117","descriptor_name":"Resins, Synthetic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0049-3848(84)90383-9","doi":"https://doi.org/10.1016/0049-3848(84)90383-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0049-3848(84)90383-9","pdf_url":null,"source":{"id":"https://openalex.org/S134546602","display_name":"Thrombosis Research","issn_l":"0049-3848","issn":["0049-3848","1879-2472"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis Research","raw_type":"journal-article"},{"id":"pmid:6740563","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6740563","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1891400877","https://openalex.org/W1969520115","https://openalex.org/W1969689224","https://openalex.org/W1972161933","https://openalex.org/W1998141776","https://openalex.org/W2008295029","https://openalex.org/W2051041406","https://openalex.org/W2060297306","https://openalex.org/W2081090776","https://openalex.org/W2084119057","https://openalex.org/W2953011512"],"related_works":["https://openalex.org/W2026995703","https://openalex.org/W6982606109","https://openalex.org/W2072522365","https://openalex.org/W2093416093","https://openalex.org/W2046265814","https://openalex.org/W2085007364","https://openalex.org/W1563551487","https://openalex.org/W82814748","https://openalex.org/W2070474757","https://openalex.org/W44448802"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}