{"id":"https://openalex.org/W2000851678","doi":"https://doi.org/10.1530/jrf.0.0730579","title":"Number of germ cells and meiotic prophase stages in fetal rat ovaries cultured in vitro","display_name":"Number of germ cells and meiotic prophase stages in fetal rat ovaries cultured in vitro","publication_year":1985,"publication_date":"1985-03-01","ids":{"openalex":"https://openalex.org/W2000851678","doi":"https://doi.org/10.1530/jrf.0.0730579","mag":"2000851678","pmid":"https://pubmed.ncbi.nlm.nih.gov/3989802"},"language":"en","primary_location":{"id":"doi:10.1530/jrf.0.0730579","doi":"https://doi.org/10.1530/jrf.0.0730579","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730579","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/73/2/jrf_73_2_034.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/73/2/jrf_73_2_034.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081534698","display_name":"J Pr\u00e9pin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Pr\u00e9pin","raw_affiliation_strings":["Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France","institution_ids":["https://openalex.org/I187986737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071686634","display_name":"C. Gibello-Kervran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Gibello-Kervran","raw_affiliation_strings":["Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France","institution_ids":["https://openalex.org/I187986737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040002787","display_name":"Gilles Charpentier","orcid":"https://orcid.org/0000-0001-6124-5712","observed_orcids":["https://orcid.org/0000-0001-6124-5712"]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"G. Charpentier","raw_affiliation_strings":["Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France","institution_ids":["https://openalex.org/I187986737"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033637760","display_name":"ALFRED JOST","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A. Jost","raw_affiliation_strings":["Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Coll\u00e8ge de France, Laboratory of Developmental Physiology, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France","institution_ids":["https://openalex.org/I187986737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I187986737"],"apc_list":null,"apc_paid":null,"fwci":1.7731,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.84621461,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"73","issue":"2","first_page":"579","last_page":"583"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/germ-cells","display_name":"germ cells","score":0.7279999852180481},{"id":"https://openalex.org/keywords/meiotic-prophase","display_name":"meiotic prophase","score":0.9520000219345093},{"id":"https://openalex.org/keywords/fetal-ovary","display_name":"fetal ovary","score":0.7549999952316284},{"id":"https://openalex.org/keywords/in-vitro-culture","display_name":"in vitro culture","score":0.6169999837875366},{"id":"https://openalex.org/keywords/leptotene","display_name":"leptotene","score":0.8659999966621399},{"id":"https://openalex.org/keywords/oogenesis","display_name":"oogenesis","score":0.5830000042915344},{"id":"https://openalex.org/keywords/germ-cell-proliferation","display_name":"germ cell proliferation","score":0.5429999828338623},{"id":"https://openalex.org/keywords/rat-fetus","display_name":"rat fetus","score":0.48899999260902405},{"id":"https://openalex.org/keywords/hormone-free-medium","display_name":"hormone-free medium","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C148196450","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis","level":3,"score":0.8367740511894226},{"id":"https://openalex.org/C45413362","wikidata":"https://www.wikidata.org/wiki/Q6013254","display_name":"Prophase","level":4,"score":0.8069850206375122},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6802970767021179},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6361531019210815},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5965090990066528},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5299649834632874},{"id":"https://openalex.org/C2780258238","wikidata":"https://www.wikidata.org/wiki/Q2520842","display_name":"Germ","level":2,"score":0.5210575461387634},{"id":"https://openalex.org/C2778324911","wikidata":"https://www.wikidata.org/wiki/Q9631","display_name":"Ovary","level":2,"score":0.48343217372894287},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38186880946159363},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.18331390619277954},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.16258159279823303},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14494532346725464},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11551639437675476},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011418","descriptor_name":"Prophase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1530/jrf.0.0730579","doi":"https://doi.org/10.1530/jrf.0.0730579","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730579","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/73/2/jrf_73_2_034.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},{"id":"pmid:3989802","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3989802","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of reproduction and fertility","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1530/jrf.0.0730579","doi":"https://doi.org/10.1530/jrf.0.0730579","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0730579","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/73/2/jrf_73_2_034.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000851678.pdf","grobid_xml":"https://content.openalex.org/works/W2000851678.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1964239620","https://openalex.org/W1999434348","https://openalex.org/W2009700990","https://openalex.org/W2013594510","https://openalex.org/W2048034518","https://openalex.org/W2062788468","https://openalex.org/W2075029530","https://openalex.org/W2484920242","https://openalex.org/W2502545861"],"related_works":["https://openalex.org/W2079203396","https://openalex.org/W2022833690","https://openalex.org/W2035570612","https://openalex.org/W2105633536","https://openalex.org/W2412432120","https://openalex.org/W2096599310","https://openalex.org/W2105443693","https://openalex.org/W7095462955","https://openalex.org/W1964489087","https://openalex.org/W2498365516"],"abstract_inverted_index":{"Ovaries":[0],"from":[1],"13.5-day-old":[2],"rat":[3],"fetuses":[4],"were":[5],"cultured":[6],"in":[7,9,50],"vitro":[8],"a":[10],"hormone-free":[11],"medium":[12],"for":[13],"up":[14],"to":[15],"8":[16],"days.":[17],"The":[18,33],"number":[19],"of":[20,45],"germ":[21,53],"cells":[22],"increased":[23],"during":[24],"the":[25,39,51],"first":[26,40],"4":[27],"days":[28],"and":[29],"then":[30],"sharply":[31],"decreased.":[32],"initial":[34],"decrease":[35],"was":[36],"concomitant":[37],"with":[38],"leptotene":[41],"stages.":[42],"All":[43],"stages":[44],"meiotic":[46],"prophase":[47],"progressively":[48],"appeared":[49],"remaining":[52],"cells.":[54]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}