{"id":"https://openalex.org/W200083751","doi":null,"title":"Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin.","display_name":"Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin.","publication_year":1992,"publication_date":"1992-10-01","ids":{"openalex":"https://openalex.org/W200083751","mag":"200083751","pmid":"https://pubmed.ncbi.nlm.nih.gov/1291474"},"language":"en","primary_location":{"id":"pmid:1291474","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1291474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian journal of physiology and pharmacology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047908533","display_name":"K.K. Soudamini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K K Soudamini","raw_affiliation_strings":["Amala Cancer Research Centre, Amala Nagar, Trichur"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amala Cancer Research Centre, Amala Nagar, Trichur","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"M C Unnikrishnan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M C Unnikrishnan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109715163","display_name":"K. B. Soni","orcid":"https://orcid.org/0000-0003-2485-3887","observed_orcids":["https://orcid.org/0000-0003-2485-3887"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K B Soni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111613049","display_name":"Ramadassan Kuttan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Kuttan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.094,"has_fulltext":false,"cited_by_count":121,"citation_normalized_percentile":{"value":0.58064516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"36","issue":"4","first_page":"239","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12758","display_name":"Saffron Plant Research Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":1.0},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cholesterol","display_name":"cholesterol","score":0.796999990940094},{"id":"https://openalex.org/keywords/carbon-tetrachloride","display_name":"carbon tetrachloride","score":0.8450000286102295},{"id":"https://openalex.org/keywords/paraquat","display_name":"paraquat","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":1.0},{"id":"https://openalex.org/keywords/oxidative-liver-injury","display_name":"oxidative liver damage","score":0.6520000100135803},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.5649999976158142},{"id":"https://openalex.org/keywords/tissue-cholesterol","display_name":"tissue cholesterol","score":0.7639999985694885},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.4259999990463257},{"id":"https://openalex.org/keywords/arterial-disease","display_name":"arterial disease","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.8978519439697266},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.8451085090637207},{"id":"https://openalex.org/C2777359374","wikidata":"https://www.wikidata.org/wiki/Q225045","display_name":"Carbon tetrachloride","level":2,"score":0.7560561895370483},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5688109397888184},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5534117221832275},{"id":"https://openalex.org/C2776527163","wikidata":"https://www.wikidata.org/wiki/Q409669","display_name":"Paraquat","level":2,"score":0.5519466400146484},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.5294979214668274},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5108287334442139},{"id":"https://openalex.org/C2993790521","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxide","level":4,"score":0.48360103368759155},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.44824275374412537},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.42883408069610596},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36043208837509155},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2881113886833191},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27745676040649414},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2465629279613495},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.19919830560684204},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.07372945547103882},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002251","descriptor_name":"Carbon Tetrachloride","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003474","descriptor_name":"Curcumin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008054","descriptor_name":"Lipid Peroxides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010269","descriptor_name":"Paraquat","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1291474","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1291474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian journal of physiology and pharmacology","raw_type":"Journal Article"},{"id":"mag:200083751","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1291474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W24228684","https://openalex.org/W2023150880","https://openalex.org/W2044682428","https://openalex.org/W2092792459","https://openalex.org/W2099023764","https://openalex.org/W2156799866"],"related_works":["https://openalex.org/W1984372682","https://openalex.org/W2239089021","https://openalex.org/W2462042218","https://openalex.org/W2979656653","https://openalex.org/W2064206471","https://openalex.org/W4240947151","https://openalex.org/W2360892103","https://openalex.org/W2910897520","https://openalex.org/W2006800631","https://openalex.org/W2767698852"],"abstract_inverted_index":{"Effect":[0],"of":[1,4,14,39,46,56,77],"oral":[2],"administration":[3,38],"curcumin":[5,40,57,78],"(diferuloyl":[6],"methane)":[7],"on":[8],"lipid":[9],"peroxidation":[10,45],"in":[11,24,48,70,80],"various":[12],"organs":[13],"mice":[15],"like":[16],"liver,":[17],"lung,":[18],"kidney":[19],"and":[20,35,66,91],"brain":[21],"was":[22,58],"studied":[23],"control":[25],"animals":[26],"as":[27,29,88],"well":[28],"those":[30],"given":[31],"carbon":[32],"tetrachloride,":[33],"paraquat":[34],"cyclophosphamide.":[36],"Oral":[37],"significantly":[41,63],"lowered":[42],"the":[43,64,75],"increased":[44],"lipids":[47],"these":[49,53,71],"tissues":[50],"produced":[51],"by":[52],"chemicals.":[54],"Administration":[55],"also":[59],"found":[60],"to":[61],"lower":[62],"serum":[65],"tissue":[67],"cholesterol":[68],"levels":[69],"animals,":[72],"indicating":[73],"that":[74],"use":[76],"helps":[79],"conditions":[81],"associated":[82],"with":[83],"peroxide":[84],"induced":[85],"injury":[86],"such":[87],"liver":[89],"damage":[90],"arterial":[92],"diseases.":[93]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}