{"id":"https://openalex.org/W2000807567","doi":"https://doi.org/10.1186/1532-429x-16-s1-p25","title":"Cardiac ECV is more robust than post-contrast cardiac T1 for evaluating temporal changes in LV fibrosis","display_name":"Cardiac ECV is more robust than post-contrast cardiac T1 for evaluating temporal changes in LV fibrosis","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2000807567","doi":"https://doi.org/10.1186/1532-429x-16-s1-p25","mag":"2000807567"},"language":"en","primary_location":{"id":"doi:10.1186/1532-429x-16-s1-p25","doi":"https://doi.org/10.1186/1532-429x-16-s1-p25","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1532-429x-16-s1-p25","pdf_url":"https://jcmr-online.biomedcentral.com/counter/pdf/10.1186/1532-429X-16-S1-P25","source":{"id":"https://openalex.org/S144688638","display_name":"Journal of Cardiovascular Magnetic Resonance","issn_l":"1097-6647","issn":["1097-6647","1532-429X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Magnetic Resonance","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jcmr-online.biomedcentral.com/counter/pdf/10.1186/1532-429X-16-S1-P25","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101103639","display_name":"Kyungpyo Hong","orcid":"https://orcid.org/0000-0002-9453-6580","observed_orcids":["https://orcid.org/0000-0002-9453-6580"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kyungpyo Hong","raw_affiliation_strings":["UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112364650","display_name":"Matthias Koopmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthias Koopmann","raw_affiliation_strings":["CARMA Center, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CARMA Center, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057622454","display_name":"Eugene G. Kholmovski","orcid":"https://orcid.org/0000-0002-3271-7247","observed_orcids":["https://orcid.org/0000-0002-3271-7247"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eugene G Kholmovski","raw_affiliation_strings":["UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025678496","display_name":"Eric C. Huang","orcid":"https://orcid.org/0000-0002-8745-0025","observed_orcids":["https://orcid.org/0000-0002-8745-0025"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric C Huang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, California, USA","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nan Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nan Hu","raw_affiliation_strings":["Division of Epidemiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029474817","display_name":"Richard M. Levenson","orcid":"https://orcid.org/0000-0002-0112-6823","observed_orcids":["https://orcid.org/0000-0002-0112-6823"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Levenson","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, California, USA","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103547279","display_name":"Sathya Vijayakumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sathya Vijayakumar","raw_affiliation_strings":["UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064060846","display_name":"Derek James Dosdall","orcid":"https://orcid.org/0000-0001-5059-6824","observed_orcids":["https://orcid.org/0000-0001-5059-6824"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Derek J Dosdall","raw_affiliation_strings":["CARMA Center, University of Utah, Salt Lake City, Utah, USA","Division of Cardiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CARMA Center, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Division of Cardiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074809926","display_name":"Ravi Ranjan","orcid":"https://orcid.org/0000-0002-3321-2435","observed_orcids":["https://orcid.org/0000-0002-3321-2435"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ravi Ranjan","raw_affiliation_strings":["CARMA Center, University of Utah, Salt Lake City, Utah, USA","Division of Cardiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CARMA Center, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Division of Cardiology, Internal Medicine, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":null,"display_name":"Daniel Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Kim","raw_affiliation_strings":["UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCAIR, Radiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101103639"],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1063715,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":null,"first_page":"P25","last_page":"P25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.6176999807357788,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.6176999807357788,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.29170000553131104,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.030700000002980232,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extracellular-volume","display_name":"extracellular volume","score":0.843999981880188},{"id":"https://openalex.org/keywords/left-ventricular-fibrosis","display_name":"left ventricular fibrosis","score":0.9440000057220459},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.8209999799728394},{"id":"https://openalex.org/keywords/cardiac-magnetic-resonance","display_name":"cardiac magnetic resonance","score":0.6600000262260437},{"id":"https://openalex.org/keywords/interstitial-fibrosis","display_name":"interstitial fibrosis","score":0.7099999785423279},{"id":"https://openalex.org/keywords/canine-model","display_name":"canine model","score":0.5519999861717224},{"id":"https://openalex.org/keywords/gadobenate-dimeglumine","display_name":"gadobenate dimeglumine","score":0.8109999895095825},{"id":"https://openalex.org/keywords/linear-mixed-models","display_name":"linear mixed models","score":0.6079999804496765},{"id":"https://openalex.org/keywords/fibrosis-quantification","display_name":"fibrosis quantification","score":0.453000009059906},{"id":"https://openalex.org/keywords/myocardial-fibrosis","display_name":"myocardial fibrosis","score":0.36399999260902405},{"id":"https://openalex.org/keywords/myocardial-t1-mapping","display_name":"myocardial T1 mapping","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C555175668","wikidata":"https://www.wikidata.org/wiki/Q539690","display_name":"Angiology","level":2,"score":0.9472850561141968},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8748328685760498},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.678631067276001},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6465244889259338},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.5541622638702393},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.5317881107330322},{"id":"https://openalex.org/C2777420927","wikidata":"https://www.wikidata.org/wiki/Q5038318","display_name":"Cardiac fibrosis","level":3,"score":0.4698345363140106},{"id":"https://openalex.org/C3018763269","wikidata":"https://www.wikidata.org/wiki/Q5038318","display_name":"Myocardial fibrosis","level":3,"score":0.46672239899635315},{"id":"https://openalex.org/C2987145844","wikidata":"https://www.wikidata.org/wiki/Q5038325","display_name":"Cardiac magnetic resonance","level":3,"score":0.4153149425983429},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.41403141617774963},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2255171835422516},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.20029863715171814},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.09259480237960815},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/1532-429x-16-s1-p25","doi":"https://doi.org/10.1186/1532-429x-16-s1-p25","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1532-429x-16-s1-p25","pdf_url":"https://jcmr-online.biomedcentral.com/counter/pdf/10.1186/1532-429X-16-S1-P25","source":{"id":"https://openalex.org/S144688638","display_name":"Journal of Cardiovascular Magnetic Resonance","issn_l":"1097-6647","issn":["1097-6647","1532-429X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Magnetic Resonance","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3035822","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4044387","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4044387","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4044387","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cardiovasc Magn Reson","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/1532-429x-16-s1-p25","doi":"https://doi.org/10.1186/1532-429x-16-s1-p25","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1532-429x-16-s1-p25","pdf_url":"https://jcmr-online.biomedcentral.com/counter/pdf/10.1186/1532-429X-16-S1-P25","source":{"id":"https://openalex.org/S144688638","display_name":"Journal of Cardiovascular Magnetic Resonance","issn_l":"1097-6647","issn":["1097-6647","1532-429X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Magnetic Resonance","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309068","display_name":"Ben B. and Iris M. Margolis Foundation","ror":"https://ror.org/03r0ha626"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000807567.pdf","grobid_xml":"https://content.openalex.org/works/W2000807567.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1903882864","https://openalex.org/W2077269059","https://openalex.org/W7101079784","https://openalex.org/W1559987515","https://openalex.org/W1772253419","https://openalex.org/W1781922193","https://openalex.org/W55178247","https://openalex.org/W2562575065","https://openalex.org/W4381125630","https://openalex.org/W4240954810"],"abstract_inverted_index":{"Post-contrast":[0],"cardiac":[1,17,30,71,98,169,319,417],"T":[2,18,72,99,152,170,213,252,274,278,320,392,410,418,518,523,567],"1":[3,19,73,84,100,153,171,181,214,253,275,279,316,321,393,411,419,434,448,519,524,568],"measurement":[4],"has":[5],"been":[6],"reported":[7],"to":[8,60,92,290],"be":[9,22],"correlated":[10],"with":[11,118,128,187,285,326,338,377,397,424,453,492,504,539],"interstitial":[12],"fibrosis":[13,112,345,355,401],"burden.":[14],"However,":[15],"post-contrast":[16,97,271,318,415,565],"can":[20],"also":[21],"influenced":[23],"by":[24],"a":[25,141,223,324,422,557],"variety":[26],"of":[27,68,88,96,133,143,184,226,305,312,323,351,380,400,421,461,465,481,496,561],"confounders,":[28,56],"including:":[29],"function,":[31,33],"renal":[32],"hematocrit,":[34],"magnetic":[35],"field":[36],"strength,":[37],"contrast":[38,49],"agent":[39,50],"type":[40],"and":[41,43,101,163,219,245,251,254,281,348,390,402,444,485,528],"dosage,":[42],"specific":[44],"delayed":[45],"imaging":[46,191],"time":[47,208],"after":[48,222],"administration.":[51],"To":[52],"compensate":[53],"for":[54,103,140,237,292,309,571],"these":[55],"investigators":[57],"have":[58],"proposed":[59],"measure":[61,560],"extracellular":[62,403,562],"volume":[63],"(ECV).":[64],"Despite":[65],"the":[66,78,94,105,166,188,385,471,497,505,512],"advantages":[67],"ECV":[69,102,255,282,371,405,455,555],"over":[70,295,542],",":[74,276,280,363,520,525,569],"systematic":[75],"studies":[76],"comparing":[77],"two":[79],"measurements":[80,294],"are":[81,394],"lacking":[82],"[":[83,175],"].":[85,124],"The":[86],"purpose":[87],"this":[89],"study":[90,552],"was":[91,263],"compare":[93],"effectiveness":[95],"evaluating":[104,572],"temporal":[106,202,386,513,549,573],"changes":[107,269,514,574],"in":[108,113,157,270,360,388,474,575],"left":[109],"ventricular":[110],"(LV)":[111],"an":[114],"established":[115],"canine":[116],"model":[117],"chronic":[119,134],"atrial":[120],"fibrillation":[121],"(AF)[":[122],"2":[123,362],"Seventeen":[125],"mongrel":[126],"dogs":[127,476],"different":[129,303,475,479],"durations":[130,304,480],"(0-22":[131],"months)":[132,308],"AF":[135,306,352,425],"were":[136,155,216,233,248,257,283,300],"scanned":[137],"multiple":[138],"times":[139],"total":[142],"46":[144],"CMR":[145],"scans":[146],"at":[147,302,342,478],"3T":[148],"(Verio,":[149],"Siemens).":[150],"Cardiac":[151,212],"maps":[154,215,322,420],"acquired":[156,217],"3":[158,176],"short-axis":[159],"planes":[160],"(base,":[161],"mid,":[162],"apex)":[164],"using":[165,265],"arrhythmia-insensitive-rapid":[167],"(AIR)":[168],"mapping":[172],"pulse":[173],"sequence":[174],"]":[177],"based":[178],"on":[179],"B":[180],"-insensitive":[182],"saturation-recovery":[183,207],"magnetization":[185],"preparation,":[186],"following":[189],"relevant":[190],"parameters:":[192],"spatial":[193],"resolution":[194,203],"=":[195,204,209,329,346,356,373,427,435,441,449,456],"1.4":[196,198],"\u00d7":[197,199],"7.0":[200],"mm,":[201],"217":[205],"ms,":[206],"600":[210],"ms.":[211],"pre-contrast":[218],"15":[220],"min":[221],"bolus":[224],"injection":[225],"Gd-BOPTA":[227],"(MultiHance;":[228],"0.15":[229],"mmol/kg).":[230],"Blood":[231],"samples":[232,337,469],"drawn":[234],"during":[235],"MRI":[236],"hematocrit":[238],"calculation.":[239],"For":[240],"image":[241],"analysis,":[242],"myocardial":[243],"contours":[244],"blood":[246,277,391,522],"pool":[247],"manually":[249],"segmented,":[250],"values":[256],"calculated.":[258],"LV":[259,273,313,335,389,409,466,473,517,566,576],"ejection":[260],"fraction":[261],"(LVEF)":[262],"calculated":[264],"cine":[266],"MRI.":[267],"Temporal":[268],"LVEF,":[272],"modeled":[284],"linear":[286],"mixed":[287],"effect":[288],"models":[289],"account":[291],"repeated":[293],"disease":[296,327,378,540],"duration.":[297],"Four":[298],"animals":[299],"sacrificed":[301,477],"(0-22.6":[307],"histologic":[310,398],"quantification":[311,399],"fibrosis.":[314,577],"Figure":[315,361],"shows":[317],"dog":[325,423],"duration":[328,353,379,426,541],"15.2":[330,428],"months,":[331],"as":[332,334],"well":[333],"tissue":[336,467],"Masson's":[339,462],"trichrome":[340,463],"staining":[341,464],"baseline":[343,484],"(interstitial":[344,354],"1.0%)":[347],"22.6":[349,487],"months":[350,429],"3.2%).":[357],"As":[358],"shown":[359],"all":[364],"four":[365,533],"parameters":[366],"(p":[367,372],"<":[368],"0.05),":[369],"except":[370,535],"0.29),":[374],"changed":[375,537],"significantly":[376,538],"22":[381,543],"months.":[382,488,544],"Note":[383],"that":[384,554],"trends":[387],"similar.":[395],"Compared":[396],"space,":[404],"agreed":[406],"better":[407],"than":[408,564],".":[412,531],"(A)":[413,516],"Representative":[414],"AIR":[416],":":[430],"(left)":[431,483],"basal":[432],"(T":[433,440,447],"737":[436],"ms),":[437,443],"(middle),":[438],"mid-ventricular":[439],"708":[442],"(right)":[445,486],"apical":[446],"740":[450],"ms)":[451],"planes,":[452],"mean":[454],"26%.":[457],"(B)":[458,521],"Histologic":[459],"evaluation":[460],"(midwall)":[468],"from":[470],"antero-lateral":[472],"AF:":[482],"All":[489,532],"specimens":[490],"displayed":[491],"10\u00d7":[493],"magnification.":[494],"Plot":[495],"estimated":[498],"regression":[499],"line":[500],"(solid":[501],"line),":[502],"along":[503],"95%":[506],"confidence":[507],"intervals":[508],"(dashed":[509],"lines),":[510],"describing":[511],"in:":[515],"(C)":[526],"ECV,":[527,536],"(D)":[529],"LVEF":[530],"parameters,":[534],"Different":[545],"colors":[546],"represent":[547],"individual":[548],"trends.":[550],"This":[551],"suggests":[553],"is":[556],"more":[558],"robust":[559],"space":[563],"especially":[570]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}