{"id":"https://openalex.org/W2000746291","doi":"https://doi.org/10.1016/s1578-2190(10)70845-3","title":"Fondaparinux and Lepirudin as Therapeutic Alternatives in a Disseminated Eczematous Skin Reaction to Low-Molecular-Weight Heparin","display_name":"Fondaparinux and Lepirudin as Therapeutic Alternatives in a Disseminated Eczematous Skin Reaction to Low-Molecular-Weight Heparin","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2000746291","doi":"https://doi.org/10.1016/s1578-2190(10)70845-3","mag":"2000746291","pmid":"https://pubmed.ncbi.nlm.nih.gov/20738979"},"language":"es","primary_location":{"id":"doi:10.1016/s1578-2190(10)70845-3","doi":"https://doi.org/10.1016/s1578-2190(10)70845-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1578-2190(10)70845-3","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1578219010708453/pdf","source":{"id":"https://openalex.org/S2755888424","display_name":"Actas Dermo-Sifiliogr\u00e1ficas","issn_l":"0001-7310","issn":["0001-7310","1578-2190","1695-4734"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Actas Dermo-Sifiliogr\u00e1ficas (English Edition)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1578219010708453/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079457204","display_name":"Diana Santiago S\u00e1nchez\u2010Mateos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130498","display_name":"Hospital Universitario de La Princesa","ror":"https://ror.org/03cg5md32","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130498","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"D.I. Santiago S\u00e1nchez-Mateos","raw_affiliation_strings":["Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain","institution_ids":["https://openalex.org/I4210130498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044363984","display_name":"Cristina Eguren","orcid":"https://orcid.org/0000-0002-0357-9228","observed_orcids":["https://orcid.org/0000-0002-0357-9228"]},"institutions":[{"id":"https://openalex.org/I4210130498","display_name":"Hospital Universitario de La Princesa","ror":"https://ror.org/03cg5md32","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130498","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C. Eguren","raw_affiliation_strings":["Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain","institution_ids":["https://openalex.org/I4210130498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024170977","display_name":"DIEGO DE ARGILA","orcid":"https://orcid.org/0000-0002-3636-1727","observed_orcids":["https://orcid.org/0000-0002-3636-1727"]},"institutions":[{"id":"https://openalex.org/I4210130498","display_name":"Hospital Universitario de La Princesa","ror":"https://ror.org/03cg5md32","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130498","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"D. de Argila","raw_affiliation_strings":["Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain","institution_ids":["https://openalex.org/I4210130498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018147144","display_name":"Javier S\u00e1nchez-P\u00e9rez","orcid":"https://orcid.org/0000-0002-4376-2393","observed_orcids":["https://orcid.org/0000-0002-4376-2393"]},"institutions":[{"id":"https://openalex.org/I4210130498","display_name":"Hospital Universitario de La Princesa","ror":"https://ror.org/03cg5md32","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130498","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. S\u00e1nchez-P\u00e9rez","raw_affiliation_strings":["Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Dermatolog\u00eda, Hospital de la Princesa, Madrid, Spain","institution_ids":["https://openalex.org/I4210130498"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5079457204"],"corresponding_institution_ids":["https://openalex.org/I4210130498"],"apc_list":{"value":2080,"currency":"USD","value_usd":2080},"apc_paid":{"value":2080,"currency":"USD","value_usd":2080},"fwci":0.4373,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.64573631,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"101","issue":"6","first_page":"556","last_page":"558"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.5185999870300293,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.5185999870300293,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12352","display_name":"Heparin-Induced Thrombocytopenia and Thrombosis","score":0.40700000524520874,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fondaparinux","display_name":"fondaparinux","score":0.968999981880188},{"id":"https://openalex.org/keywords/lepirudin","display_name":"lepirudin","score":1.0},{"id":"https://openalex.org/keywords/low-molecular-weight-heparin","display_name":"low molecular weight heparin","score":0.9190000295639038},{"id":"https://openalex.org/keywords/alternative-anticoagulants","display_name":"anticoagulation alternatives","score":0.703000009059906},{"id":"https://openalex.org/keywords/heparin-induced-thrombocytopenia","display_name":"heparin-induced thrombocytopenia","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C2780205058","wikidata":"https://www.wikidata.org/wiki/Q3271949","display_name":"Lepirudin","level":5,"score":0.9448754787445068},{"id":"https://openalex.org/C2776877702","wikidata":"https://www.wikidata.org/wiki/Q27077698","display_name":"Fondaparinux","level":4,"score":0.7368409037590027},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46938297152519226},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4665047526359558},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.45510944724082947},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.18091487884521484},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10459631681442261},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.06923723220825195},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.0},{"id":"https://openalex.org/C2777292125","wikidata":"https://www.wikidata.org/wiki/Q409166","display_name":"Thrombin","level":3,"score":0.0},{"id":"https://openalex.org/C2779612170","wikidata":"https://www.wikidata.org/wiki/Q474880","display_name":"Argatroban","level":4,"score":0.0},{"id":"https://openalex.org/C2991741193","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thromboembolism","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077425","descriptor_name":"Fondaparinux","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006495","descriptor_name":"Heparin, Low-Molecular-Weight","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006629","descriptor_name":"Hirudins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017449","descriptor_name":"Dermatitis, Allergic Contact","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1578-2190(10)70845-3","doi":"https://doi.org/10.1016/s1578-2190(10)70845-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1578-2190(10)70845-3","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1578219010708453/pdf","source":{"id":"https://openalex.org/S2755888424","display_name":"Actas Dermo-Sifiliogr\u00e1ficas","issn_l":"0001-7310","issn":["0001-7310","1578-2190","1695-4734"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Actas Dermo-Sifiliogr\u00e1ficas (English Edition)","raw_type":"journal-article"},{"id":"pmid:20738979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20738979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Actas dermo-sifiliograficas","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1016/s1578-2190(10)70845-3","doi":"https://doi.org/10.1016/s1578-2190(10)70845-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1578-2190(10)70845-3","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1578219010708453/pdf","source":{"id":"https://openalex.org/S2755888424","display_name":"Actas Dermo-Sifiliogr\u00e1ficas","issn_l":"0001-7310","issn":["0001-7310","1578-2190","1695-4734"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Actas Dermo-Sifiliogr\u00e1ficas (English Edition)","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000746291.pdf","grobid_xml":"https://content.openalex.org/works/W2000746291.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1967511570","https://openalex.org/W1978380458","https://openalex.org/W2036103062","https://openalex.org/W2042389981","https://openalex.org/W2059535273","https://openalex.org/W2133796795","https://openalex.org/W2163474363","https://openalex.org/W2396316242"],"related_works":["https://openalex.org/W1969741146","https://openalex.org/W7098015574","https://openalex.org/W2078395178","https://openalex.org/W1984372085","https://openalex.org/W2430880073","https://openalex.org/W2148026354","https://openalex.org/W1967511570","https://openalex.org/W2783118207","https://openalex.org/W2012626983","https://openalex.org/W2111019281"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}