{"id":"https://openalex.org/W200073292","doi":"https://doi.org/10.1007/978-3-662-22325-3_3","title":"The Biochemistry of PRE-mRNA Splicing","display_name":"The Biochemistry of PRE-mRNA Splicing","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W200073292","doi":"https://doi.org/10.1007/978-3-662-22325-3_3","mag":"200073292"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-662-22325-3_3","doi":"https://doi.org/10.1007/978-3-662-22325-3_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-662-22325-3_3","pdf_url":null,"source":{"id":"https://openalex.org/S4210221981","display_name":"Molecular biology intelligence unit","issn_l":"1431-0414","issn":["1431-0414"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Intelligence Unit","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W214518591","display_name":"Pre-mRNA Processing"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111588655","display_name":"Angela Kr\u00e4mer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Angela Kr\u00e4mer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5111588655"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.6969,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.98329019,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"35","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pre-mrna-splicing","display_name":"pre-mRNA splicing","score":0.9900000095367432},{"id":"https://openalex.org/keywords/intron-removal","display_name":"intron removal","score":0.8130000233650208},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7879999876022339},{"id":"https://openalex.org/keywords/spliceosome","display_name":"spliceosome","score":0.5270000100135803},{"id":"https://openalex.org/keywords/splice-site-selection","display_name":"splice site selection","score":0.5720000267028809},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.8069999814033508},{"id":"https://openalex.org/keywords/trans-acting-factors","display_name":"trans-acting factors","score":0.9549999833106995},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.8700000047683716},{"id":"https://openalex.org/keywords/protein-isoforms","display_name":"protein isoforms","score":0.8600000143051147},{"id":"https://openalex.org/keywords/in-frame-stop-codon","display_name":"in-frame stop codon","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.7924088835716248},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.7872638702392578},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.7405276298522949},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.6852585077285767},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6639247536659241},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6159242391586304},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5771802663803101},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5432982444763184},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.5334881544113159},{"id":"https://openalex.org/C42576000","wikidata":"https://www.wikidata.org/wiki/Q5420618","display_name":"Exonic splicing enhancer","level":5,"score":0.46076488494873047},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43573176860809326},{"id":"https://openalex.org/C73758832","wikidata":"https://www.wikidata.org/wiki/Q7578564","display_name":"Splicing factor","level":5,"score":0.4299696981906891},{"id":"https://openalex.org/C102063271","wikidata":"https://www.wikidata.org/wiki/Q7243183","display_name":"Precursor mRNA","level":5,"score":0.4248027205467224},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.27787449955940247}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-662-22325-3_3","doi":"https://doi.org/10.1007/978-3-662-22325-3_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-662-22325-3_3","pdf_url":null,"source":{"id":"https://openalex.org/S4210221981","display_name":"Molecular biology intelligence unit","issn_l":"1431-0414","issn":["1431-0414"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Intelligence Unit","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":200,"referenced_works":["https://openalex.org/W41372527","https://openalex.org/W92004496","https://openalex.org/W131136481","https://openalex.org/W215272066","https://openalex.org/W235098460","https://openalex.org/W268783301","https://openalex.org/W269326419","https://openalex.org/W320630928","https://openalex.org/W323731211","https://openalex.org/W979014048","https://openalex.org/W1045127477","https://openalex.org/W1497140289","https://openalex.org/W1508168356","https://openalex.org/W1515351996","https://openalex.org/W1553769217","https://openalex.org/W1585429518","https://openalex.org/W1589532501","https://openalex.org/W1605091261","https://openalex.org/W1647720439","https://openalex.org/W1657208855","https://openalex.org/W1706843564","https://openalex.org/W1807274056","https://openalex.org/W1846763343","https://openalex.org/W1849895108","https://openalex.org/W1871905727","https://openalex.org/W1888077955","https://openalex.org/W1895322566","https://openalex.org/W1899339598","https://openalex.org/W1907972331","https://openalex.org/W1966123525","https://openalex.org/W1967618732","https://openalex.org/W1968276418","https://openalex.org/W1968843636","https://openalex.org/W1971956957","https://openalex.org/W1973916539","https://openalex.org/W1974293813","https://openalex.org/W1974296243","https://openalex.org/W1974630548","https://openalex.org/W1975014999","https://openalex.org/W1975580175","https://openalex.org/W1975642325","https://openalex.org/W1975677828","https://openalex.org/W1977304564","https://openalex.org/W1979455742","https://openalex.org/W1980424685","https://openalex.org/W1980428104","https://openalex.org/W1981598173","https://openalex.org/W1982559739","https://openalex.org/W1982610079","https://openalex.org/W1983800032","https://openalex.org/W1984116290","https://openalex.org/W1984487835","https://openalex.org/W1985195611","https://openalex.org/W1986121171","https://openalex.org/W1988271866","https://openalex.org/W1988455121","https://openalex.org/W1988498926","https://openalex.org/W1990232676","https://openalex.org/W1991251351","https://openalex.org/W1993556086","https://openalex.org/W1994046562","https://openalex.org/W1999265573","https://openalex.org/W1999890106","https://openalex.org/W2001509514","https://openalex.org/W2001730018","https://openalex.org/W2002986711","https://openalex.org/W2003213264","https://openalex.org/W2004224961","https://openalex.org/W2004298887","https://openalex.org/W2006144062","https://openalex.org/W2006628267","https://openalex.org/W2008422577","https://openalex.org/W2009103135","https://openalex.org/W2009598373","https://openalex.org/W2010696389","https://openalex.org/W2013002081","https://openalex.org/W2013287897","https://openalex.org/W2013306113","https://openalex.org/W2013836961","https://openalex.org/W2013955971","https://openalex.org/W2014427312","https://openalex.org/W2014551753","https://openalex.org/W2014791263","https://openalex.org/W2015415328","https://openalex.org/W2015816723","https://openalex.org/W2015856496","https://openalex.org/W2017125983","https://openalex.org/W2020296243","https://openalex.org/W2021054898","https://openalex.org/W2022346667","https://openalex.org/W2022706985","https://openalex.org/W2023199595","https://openalex.org/W2024170620","https://openalex.org/W2024588724","https://openalex.org/W2027183714","https://openalex.org/W2036228528","https://openalex.org/W2039347057","https://openalex.org/W2039669793","https://openalex.org/W2039762550","https://openalex.org/W2041421251","https://openalex.org/W2041847911","https://openalex.org/W2042188415","https://openalex.org/W2043307368","https://openalex.org/W2043583718","https://openalex.org/W2044297968","https://openalex.org/W2047606105","https://openalex.org/W2047944486","https://openalex.org/W2048630205","https://openalex.org/W2050110866","https://openalex.org/W2051082289","https://openalex.org/W2052319720","https://openalex.org/W2053524479","https://openalex.org/W2054306198","https://openalex.org/W2054865688","https://openalex.org/W2057479447","https://openalex.org/W2061420032","https://openalex.org/W2063790655","https://openalex.org/W2064448615","https://openalex.org/W2066157608","https://openalex.org/W2066552951","https://openalex.org/W2067000354","https://openalex.org/W2067708544","https://openalex.org/W2068381061","https://openalex.org/W2068411631","https://openalex.org/W2071032973","https://openalex.org/W2071112476","https://openalex.org/W2071336621","https://openalex.org/W2073105366","https://openalex.org/W2073601378","https://openalex.org/W2074427164","https://openalex.org/W2075086594","https://openalex.org/W2075339456","https://openalex.org/W2075362101","https://openalex.org/W2076304484","https://openalex.org/W2076849957","https://openalex.org/W2077369944","https://openalex.org/W2078819000","https://openalex.org/W2080236124","https://openalex.org/W2080568795","https://openalex.org/W2080823878","https://openalex.org/W2082468024","https://openalex.org/W2085324214","https://openalex.org/W2085368553","https://openalex.org/W2085956911","https://openalex.org/W2090643890","https://openalex.org/W2090697468","https://openalex.org/W2091075468","https://openalex.org/W2091423718","https://openalex.org/W2091495597","https://openalex.org/W2091924321","https://openalex.org/W2091955128","https://openalex.org/W2094430977","https://openalex.org/W2094972420","https://openalex.org/W2097054401","https://openalex.org/W2097204779","https://openalex.org/W2098219409","https://openalex.org/W2100179968","https://openalex.org/W2101679570","https://openalex.org/W2103140784","https://openalex.org/W2104403651","https://openalex.org/W2109644636","https://openalex.org/W2109745480","https://openalex.org/W2110090133","https://openalex.org/W2112046972","https://openalex.org/W2115002325","https://openalex.org/W2116884417","https://openalex.org/W2117976997","https://openalex.org/W2119970727","https://openalex.org/W2120315535","https://openalex.org/W2122071753","https://openalex.org/W2125304732","https://openalex.org/W2125959590","https://openalex.org/W2127629841","https://openalex.org/W2133143001","https://openalex.org/W2134095387","https://openalex.org/W2134201576","https://openalex.org/W2135466312","https://openalex.org/W2136893558","https://openalex.org/W2139727828","https://openalex.org/W2139793149","https://openalex.org/W2142760341","https://openalex.org/W2148900689","https://openalex.org/W2151078655","https://openalex.org/W2153635048","https://openalex.org/W2157343576","https://openalex.org/W2165543326","https://openalex.org/W2168649579","https://openalex.org/W2168823577","https://openalex.org/W2170212246","https://openalex.org/W2171878484","https://openalex.org/W2197280492","https://openalex.org/W2253075914","https://openalex.org/W2267993411","https://openalex.org/W4237655687","https://openalex.org/W4301673616","https://openalex.org/W6665093875","https://openalex.org/W6691056587","https://openalex.org/W7096141944","https://openalex.org/W7096581874","https://openalex.org/W7096858812"],"related_works":["https://openalex.org/W944452251","https://openalex.org/W1520649466","https://openalex.org/W53255216","https://openalex.org/W1831474080","https://openalex.org/W4243873785","https://openalex.org/W2235555101","https://openalex.org/W1521822009","https://openalex.org/W2006058149","https://openalex.org/W2983920702","https://openalex.org/W4240406038"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}