{"id":"https://openalex.org/W2000705887","doi":"https://doi.org/10.4155/cli.11.28","title":"Endocrine therapy for prostate cancer: review of the latest clinical evidence","display_name":"Endocrine therapy for prostate cancer: review of the latest clinical evidence","publication_year":2011,"publication_date":"2011-04-01","ids":{"openalex":"https://openalex.org/W2000705887","doi":"https://doi.org/10.4155/cli.11.28","mag":"2000705887"},"language":"en","primary_location":{"id":"doi:10.4155/cli.11.28","doi":"https://doi.org/10.4155/cli.11.28","is_oa":false,"landing_page_url":"https://doi.org/10.4155/cli.11.28","pdf_url":null,"source":{"id":"https://openalex.org/S2765044866","display_name":"Clinical Investigation","issn_l":"2041-6792","issn":["2041-6792","2041-6806"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112083187","display_name":"Che\u2010Kai Tsao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Che-Kai Tsao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041565080","display_name":"Sonia Maria Seng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sonia Seng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078027978","display_name":"William K. Oh","orcid":"https://orcid.org/0000-0001-5113-8147","observed_orcids":["https://orcid.org/0000-0001-5113-8147"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William K Oh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5018275141","display_name":"Matthew D. Galsky","orcid":"https://orcid.org/0000-0001-7655-9378","observed_orcids":["https://orcid.org/0000-0001-7655-9378"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew D Galsky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13857909,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":"4","first_page":"533","last_page":"541"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9340000152587891},{"id":"https://openalex.org/keywords/endocrine-therapy","display_name":"endocrine therapy","score":0.9559999704360962},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9679999947547913},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.8659999966621399},{"id":"https://openalex.org/keywords/combination-hormonal-therapy","display_name":"combination hormonal therapy","score":0.9769999980926514}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9034540057182312},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6883643269538879},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.5114006400108337},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4814288318157196},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4288119077682495},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3274238109588623},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29712149500846863},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.11861449480056763}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4155/cli.11.28","doi":"https://doi.org/10.4155/cli.11.28","is_oa":false,"landing_page_url":"https://doi.org/10.4155/cli.11.28","pdf_url":null,"source":{"id":"https://openalex.org/S2765044866","display_name":"Clinical Investigation","issn_l":"2041-6792","issn":["2041-6792","2041-6806"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Investigation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6299999952316284}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W165132104","https://openalex.org/W1536788832","https://openalex.org/W1580523172","https://openalex.org/W1816722347","https://openalex.org/W1968086690","https://openalex.org/W1983094204","https://openalex.org/W1996437958","https://openalex.org/W1998721649","https://openalex.org/W2003955264","https://openalex.org/W2005658600","https://openalex.org/W2008549629","https://openalex.org/W2014027028","https://openalex.org/W2016880167","https://openalex.org/W2034710772","https://openalex.org/W2037622469","https://openalex.org/W2040307998","https://openalex.org/W2040880223","https://openalex.org/W2049507843","https://openalex.org/W2067890225","https://openalex.org/W2072685254","https://openalex.org/W2077301757","https://openalex.org/W2083926838","https://openalex.org/W2085847636","https://openalex.org/W2086554145","https://openalex.org/W2086882324","https://openalex.org/W2088132910","https://openalex.org/W2093125109","https://openalex.org/W2093468737","https://openalex.org/W2095873383","https://openalex.org/W2097226696","https://openalex.org/W2101606728","https://openalex.org/W2101995865","https://openalex.org/W2107850854","https://openalex.org/W2108494968","https://openalex.org/W2110155536","https://openalex.org/W2113569308","https://openalex.org/W2117296712","https://openalex.org/W2119036448","https://openalex.org/W2119504728","https://openalex.org/W2130953497","https://openalex.org/W2133489902","https://openalex.org/W2134256060","https://openalex.org/W2134825260","https://openalex.org/W2136750233","https://openalex.org/W2138885835","https://openalex.org/W2147405625","https://openalex.org/W2150609534","https://openalex.org/W2150741140","https://openalex.org/W2159448513","https://openalex.org/W2161775120","https://openalex.org/W2165631552","https://openalex.org/W2165782799","https://openalex.org/W2168011358","https://openalex.org/W2170544517","https://openalex.org/W2260909707","https://openalex.org/W2318024704","https://openalex.org/W2464502417","https://openalex.org/W2520127642","https://openalex.org/W2613104851","https://openalex.org/W4233036449","https://openalex.org/W4254037116"],"related_works":["https://openalex.org/W299695548","https://openalex.org/W2890064938","https://openalex.org/W3103933760","https://openalex.org/W3171449477","https://openalex.org/W4226145355","https://openalex.org/W2384122898","https://openalex.org/W209797606","https://openalex.org/W151774199","https://openalex.org/W4281885123","https://openalex.org/W4380886535"],"abstract_inverted_index":{"Prostate":[0],"cancer,":[1],"the":[2,17,20,45,72,79,88],"most":[3,26],"common":[4],"nonskin":[5],"cancer":[6],"in":[7,16,71,78,102],"men,":[8],"is":[9],"estimated":[10],"to":[11,50],"cause":[12],"27,000":[13],"deaths":[14],"annually":[15],"USA.":[18],"With":[19],"advent":[21],"of":[22,35,63,74,81,90,98],"prostate-specific":[23],"antigen":[24],"screening,":[25],"are":[27],"diagnosed":[28],"with":[29,94],"local":[30,42],"disease,":[31],"but":[32],"approximately":[33],"one-third":[34],"patients":[36],"ultimately":[37],"develop":[38],"recurrence":[39],"despite":[40],"definitive":[41],"therapy.":[43],"Despite":[44],"high":[46],"initial":[47],"response":[48],"rate":[49],"androgen":[51,64,92],"deprivation,":[52],"castration":[53],"resistance":[54,65],"eventually":[55],"develops.":[56],"In":[57],"this":[58,103],"article,":[59],"we":[60],"examine":[61],"mechanisms":[62],"and":[66],"further":[67],"discuss":[68],"current":[69,95],"progress":[70],"development":[73],"novel":[75],"endocrine":[76],"therapy":[77,101],"treatment":[80],"castration-resistant":[82],"prostate":[83],"cancer.":[84],"We":[85],"also":[86],"explore":[87],"rationale":[89],"complete":[91],"blockade,":[93],"ongoing":[96],"investigation":[97],"combination":[99],"hormonal":[100],"context.":[104]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}