{"id":"https://openalex.org/W2000702097","doi":"https://doi.org/10.1117/12.426752","title":"Electrical and optical methods for the manipulation and analyses of single cells","display_name":"Electrical and optical methods for the manipulation and analyses of single cells","publication_year":2001,"publication_date":"2001-05-22","ids":{"openalex":"https://openalex.org/W2000702097","doi":"https://doi.org/10.1117/12.426752","mag":"2000702097"},"language":"en","primary_location":{"id":"doi:10.1117/12.426752","doi":"https://doi.org/10.1117/12.426752","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.426752","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035797201","display_name":"Daniel T. Chiu","orcid":"https://orcid.org/0000-0003-2964-9578","observed_orcids":["https://orcid.org/0000-0003-2964-9578"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel T. Chiu","raw_affiliation_strings":["Univ. of Washington (United States)","University of Washington, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Washington (United States)","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"University of Washington, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005721769","display_name":"Maximilian Davidson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Maximilian Davidson","raw_affiliation_strings":["Goteborg Univ. (Sweden)","Go\u0308teborg University, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Goteborg Univ. (Sweden)","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Go\u0308teborg University, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030163104","display_name":"Anette Str\u00f6mberg","orcid":"https://orcid.org/0000-0002-5792-7240","observed_orcids":["https://orcid.org/0000-0002-5792-7240"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anette Stroemberg","raw_affiliation_strings":["Goteborg Univ. (Sweden)","Go\u0308teborg University, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Goteborg Univ. (Sweden)","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Go\u0308teborg University, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064506025","display_name":"Frida Rytts\u00e9n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Frida Ryttsen","raw_affiliation_strings":["Goteborg Univ. (Sweden)","Go\u0308teborg University, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Goteborg Univ. (Sweden)","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Go\u0308teborg University, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009079136","display_name":"Owe Orwar","orcid":"https://orcid.org/0000-0001-6818-7033","observed_orcids":["https://orcid.org/0000-0001-6818-7033"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Owe Orwar","raw_affiliation_strings":["Goteborg Univ. (Sweden)","Go\u0308teborg University, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Goteborg Univ. (Sweden)","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Go\u0308teborg University, Sweden","institution_ids":["https://openalex.org/I881427289"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.13550212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4255","issue":null,"first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10490","display_name":"Orbital Angular Momentum in Optics","score":0.2273000031709671,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.08129999786615372,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-cell-manipulation","display_name":"single-cell manipulation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/electroporation","display_name":"electroporation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/electrofusion","display_name":"electrofusion","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ultramicroelectrodes","display_name":"ultramicroelectrodes","score":0.8880000114440918},{"id":"https://openalex.org/keywords/optical-tweezers","display_name":"optical tweezers","score":0.9679999947547913},{"id":"https://openalex.org/keywords/organelle-isolation","display_name":"organelle isolation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/liposomes","display_name":"liposomes","score":0.7900000214576721},{"id":"https://openalex.org/keywords/cellular-microenvironment","display_name":"cell microenvironment","score":0.5249999761581421},{"id":"https://openalex.org/keywords/single-cell-analysis","display_name":"single-cell analysis","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46061065793037415},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3330402076244354},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.31064802408218384}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.426752","doi":"https://doi.org/10.1117/12.426752","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.426752","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7","score":0.4300000071525574}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306315","display_name":"Camille and Henry Dreyfus Foundation","ror":"https://ror.org/019p8h045"},{"id":"https://openalex.org/F4320320939","display_name":"Swedish Foundation for International Cooperation in Research and Higher Education","ror":"https://ror.org/0561xc723"},{"id":"https://openalex.org/F4320320940","display_name":"Stiftelsen f\u00f6r\u00a0Strategisk Forskning","ror":"https://ror.org/044wr7g58"},{"id":"https://openalex.org/F4320335354","display_name":"Strategic Research Council","ror":"https://ror.org/02vtq1a86"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2152510857","https://openalex.org/W2050687498","https://openalex.org/W4407583504","https://openalex.org/W2137439211","https://openalex.org/W2516409644","https://openalex.org/W2098804601","https://openalex.org/W2398786292","https://openalex.org/W2006069125","https://openalex.org/W2141848463","https://openalex.org/W2132840753"],"abstract_inverted_index":{"This":[0],"paper":[1],"describes":[2],"the":[3,14,26,54,81,84,90],"use":[4,27],"of":[5,17,28,56,89],"focused":[6,10,21,50],"electric":[7,22],"fields":[8,12],"and":[9,39,44,78,87],"optical":[11,51,58],"for":[13,83],"high-resolution":[15,85],"manipulation":[16],"single":[18,64],"cells.":[19],"A":[20,49],"field,":[23,52],"obtained":[24],"with":[25,45,76],"ultramicroelectrodes":[29],"(tip":[30],"diameter":[31],"approximately":[32],"5":[33],"\u03bcm),":[34],"is":[35,60],"used":[36,61],"to":[37,62,72],"electroporate":[38],"electrofuse":[40],"individual":[41],"cells":[42],"selectively":[43],"high":[46],"spatial":[47],"resolution.":[48],"in":[53],"form":[55],"an":[57],"tweezer,":[59],"isolate":[63],"organelles":[65],"from":[66],"a":[67],"cell":[68,82],"as":[69,71],"well":[70],"position":[73],"liposomes":[74],"incorporated":[75],"receptors":[77],"transporters":[79],"along":[80],"sampling":[86],"probing":[88],"cellular":[91],"microenvironment.":[92]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}