{"id":"https://openalex.org/W2000692960","doi":"https://doi.org/10.1208/s12249-012-9857-5","title":"Structure Relationship of Cationic Lipids on Gene Transfection Mediated by Cationic Liposomes","display_name":"Structure Relationship of Cationic Lipids on Gene Transfection Mediated by Cationic Liposomes","publication_year":2012,"publication_date":"2012-09-24","ids":{"openalex":"https://openalex.org/W2000692960","doi":"https://doi.org/10.1208/s12249-012-9857-5","mag":"2000692960","pmid":"https://pubmed.ncbi.nlm.nih.gov/23007192","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3513429"},"language":"en","primary_location":{"id":"doi:10.1208/s12249-012-9857-5","doi":"https://doi.org/10.1208/s12249-012-9857-5","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-012-9857-5","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-012-9857-5.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1208/s12249-012-9857-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044063618","display_name":"Orapan Paecharoenchai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86677382","display_name":"Silpakorn University","ror":"https://ror.org/02d0tyt78","country_code":"TH","type":"education","lineage":["https://openalex.org/I86677382"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Orapan Paecharoenchai","raw_affiliation_strings":["Pharmaceutical Development of Green Innovations Group, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","Silpakorn  University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Development of Green Innovations Group, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","institution_ids":["https://openalex.org/I86677382"]},{"raw_affiliation_string":"Silpakorn  University","institution_ids":["https://openalex.org/I86677382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023384238","display_name":"Nattisa Niyomtham","orcid":"https://orcid.org/0000-0003-2233-918X","observed_orcids":["https://orcid.org/0000-0003-2233-918X"]},"institutions":[{"id":"https://openalex.org/I58196637","display_name":"Ramkhamhaeng University","ror":"https://ror.org/00mrw8k38","country_code":"TH","type":"education","lineage":["https://openalex.org/I58196637"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nattisa Niyomtham","raw_affiliation_strings":["Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand","RAMKHAMHAENG UNIVERSITY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand","institution_ids":["https://openalex.org/I58196637"]},{"raw_affiliation_string":"RAMKHAMHAENG UNIVERSITY","institution_ids":["https://openalex.org/I58196637"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055516656","display_name":"Auayporn Apirakaramwong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86677382","display_name":"Silpakorn University","ror":"https://ror.org/02d0tyt78","country_code":"TH","type":"education","lineage":["https://openalex.org/I86677382"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Auayporn Apirakaramwong","raw_affiliation_strings":["Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","Silpakorn  University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","institution_ids":["https://openalex.org/I86677382"]},{"raw_affiliation_string":"Silpakorn  University","institution_ids":["https://openalex.org/I86677382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046756346","display_name":"Tanasait Ngawhirunpat","orcid":"https://orcid.org/0000-0003-4260-6097","observed_orcids":["https://orcid.org/0000-0003-4260-6097"]},"institutions":[{"id":"https://openalex.org/I86677382","display_name":"Silpakorn University","ror":"https://ror.org/02d0tyt78","country_code":"TH","type":"education","lineage":["https://openalex.org/I86677382"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Tanasait Ngawhirunpat","raw_affiliation_strings":["Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","Silpakorn  University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","institution_ids":["https://openalex.org/I86677382"]},{"raw_affiliation_string":"Silpakorn  University","institution_ids":["https://openalex.org/I86677382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108166839","display_name":"Theerasak Rojanarata","orcid":"https://orcid.org/0000-0002-5309-1896","observed_orcids":["https://orcid.org/0000-0002-5309-1896"]},"institutions":[{"id":"https://openalex.org/I86677382","display_name":"Silpakorn University","ror":"https://ror.org/02d0tyt78","country_code":"TH","type":"education","lineage":["https://openalex.org/I86677382"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Theerasak Rojanarata","raw_affiliation_strings":["Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","Silpakorn  University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","institution_ids":["https://openalex.org/I86677382"]},{"raw_affiliation_string":"Silpakorn  University","institution_ids":["https://openalex.org/I86677382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087193776","display_name":"Boon\u2010ek Yingyongnarongkul","orcid":"https://orcid.org/0000-0002-9513-7282","observed_orcids":["https://orcid.org/0000-0002-9513-7282"]},"institutions":[{"id":"https://openalex.org/I58196637","display_name":"Ramkhamhaeng University","ror":"https://ror.org/00mrw8k38","country_code":"TH","type":"education","lineage":["https://openalex.org/I58196637"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Boon-ek Yingyongnarongkul","raw_affiliation_strings":["Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand","RAMKHAMHAENG UNIVERSITY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand","institution_ids":["https://openalex.org/I58196637"]},{"raw_affiliation_string":"RAMKHAMHAENG UNIVERSITY","institution_ids":["https://openalex.org/I58196637"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011581277","display_name":"Praneet Opanasopit","orcid":"https://orcid.org/0000-0002-4878-2529","observed_orcids":["https://orcid.org/0000-0002-4878-2529"]},"institutions":[{"id":"https://openalex.org/I86677382","display_name":"Silpakorn University","ror":"https://ror.org/02d0tyt78","country_code":"TH","type":"education","lineage":["https://openalex.org/I86677382"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Praneet Opanasopit","raw_affiliation_strings":["Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","Silpakorn  University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand","institution_ids":["https://openalex.org/I86677382"]},{"raw_affiliation_string":"Silpakorn  University","institution_ids":["https://openalex.org/I86677382"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5011581277"],"corresponding_institution_ids":["https://openalex.org/I86677382"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.8192,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.66311925,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"4","first_page":"1302","last_page":"1308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cationic-liposomes","display_name":"cationic liposomes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/transfection","display_name":"transfection","score":0.9750000238418579},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.8489999771118164},{"id":"https://openalex.org/keywords/spermine","display_name":"spermine","score":0.6620000004768372},{"id":"https://openalex.org/keywords/acyl-chain-length","display_name":"acyl chain length","score":0.9929999709129333},{"id":"https://openalex.org/keywords/lipoplexes","display_name":"lipoplexes","score":0.8220000267028809},{"id":"https://openalex.org/keywords/transfection-efficiency","display_name":"transfection efficiency","score":0.8650000095367432},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.7229999899864197},{"id":"https://openalex.org/keywords/lipofectamine-2000","display_name":"Lipofectamine 2000","score":0.824999988079071},{"id":"https://openalex.org/keywords/gene-delivery-vehicles","display_name":"gene carriers","score":0.6029999852180481},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2776109719","wikidata":"https://www.wikidata.org/wiki/Q424597","display_name":"Spermine","level":3,"score":0.9254708290100098},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.841467022895813},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.8393967151641846},{"id":"https://openalex.org/C155887181","wikidata":"https://www.wikidata.org/wiki/Q5053552","display_name":"Cationic liposome","level":4,"score":0.7449616193771362},{"id":"https://openalex.org/C183882617","wikidata":"https://www.wikidata.org/wiki/Q3046749","display_name":"Cationic polymerization","level":2,"score":0.7442457675933838},{"id":"https://openalex.org/C49923114","wikidata":"https://www.wikidata.org/wiki/Q17139621","display_name":"Lipofectamine","level":5,"score":0.6823216080665588},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6476743817329407},{"id":"https://openalex.org/C2778271344","wikidata":"https://www.wikidata.org/wiki/Q903395","display_name":"Agarose gel electrophoresis","level":3,"score":0.48948633670806885},{"id":"https://openalex.org/C2777366897","wikidata":"https://www.wikidata.org/wiki/Q847482","display_name":"HeLa","level":3,"score":0.47272318601608276},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.4395439028739929},{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.4328133463859558},{"id":"https://openalex.org/C2780115381","wikidata":"https://www.wikidata.org/wiki/Q421959","display_name":"Polyamine","level":2,"score":0.4255632758140564},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3904343247413635},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.24339613318443298},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.22427040338516235},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1953277289867401},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.18031787872314453},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.14329877495765686},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.09633961319923401},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05797302722930908},{"id":"https://openalex.org/C92087593","wikidata":"https://www.wikidata.org/wiki/Q427389","display_name":"Vector (molecular biology)","level":4,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004983","descriptor_name":"Ethanolamines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013096","descriptor_name":"Spermine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049452","descriptor_name":"Green Fluorescent Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D049452","descriptor_name":"Green Fluorescent Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1208/s12249-012-9857-5","doi":"https://doi.org/10.1208/s12249-012-9857-5","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-012-9857-5","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-012-9857-5.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2771025","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3513429","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:23007192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23007192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3513429","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3513429/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1208/s12249-012-9857-5","doi":"https://doi.org/10.1208/s12249-012-9857-5","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-012-9857-5","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-012-9857-5.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320336192","display_name":"Center of Excellence for Innovation in Chemistry","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000692960.pdf","grobid_xml":"https://content.openalex.org/works/W2000692960.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W23797736","https://openalex.org/W1932798458","https://openalex.org/W1972531115","https://openalex.org/W1982770157","https://openalex.org/W1985232912","https://openalex.org/W1989289517","https://openalex.org/W1991303534","https://openalex.org/W2003874381","https://openalex.org/W2005446730","https://openalex.org/W2008073451","https://openalex.org/W2018295448","https://openalex.org/W2023947480","https://openalex.org/W2025199379","https://openalex.org/W2025592250","https://openalex.org/W2033222233","https://openalex.org/W2043630370","https://openalex.org/W2062820647","https://openalex.org/W2071328859","https://openalex.org/W2071732315","https://openalex.org/W2080648192","https://openalex.org/W2084652077","https://openalex.org/W2085487522","https://openalex.org/W2092482435","https://openalex.org/W2120742252","https://openalex.org/W2128446423"],"related_works":["https://openalex.org/W1971633729","https://openalex.org/W4409418943","https://openalex.org/W4205255195","https://openalex.org/W2210923860","https://openalex.org/W4403016201","https://openalex.org/W2001378328","https://openalex.org/W4319160174","https://openalex.org/W1974578185","https://openalex.org/W1978285414","https://openalex.org/W117503492"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}