{"id":"https://openalex.org/W2000676139","doi":"https://doi.org/10.1118/1.596592","title":"Dose\u2010volume considerations with linear programming optimization","display_name":"Dose\u2010volume considerations with linear programming optimization","publication_year":1991,"publication_date":"1991-11-01","ids":{"openalex":"https://openalex.org/W2000676139","doi":"https://doi.org/10.1118/1.596592","mag":"2000676139","pmid":"https://pubmed.ncbi.nlm.nih.gov/1753905"},"language":"en","primary_location":{"id":"doi:10.1118/1.596592","doi":"https://doi.org/10.1118/1.596592","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.596592","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111368240","display_name":"Steven M. Morrill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven M. Morrill","raw_affiliation_strings":["Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105003661","display_name":"Richard G. Lane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard G. Lane","raw_affiliation_strings":["Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jorge A. Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jorge A. Wong","raw_affiliation_strings":["Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103453917","display_name":"Isaac I. Rosen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Isaac I. Rosen","raw_affiliation_strings":["Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Therapy, The University of Texas Medical Branch, Galveston, Texas 77550","institution_ids":["https://openalex.org/I55302922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I55302922"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":{"value":0.19277108,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"18","issue":"6","first_page":"1201","last_page":"1210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dose-volume-constraints","display_name":"dose-volume constraints","score":0.9589999914169312},{"id":"https://openalex.org/keywords/linear-programming","display_name":"linear programming","score":0.8870000243186951},{"id":"https://openalex.org/keywords/conformal-radiotherapy","display_name":"conformal radiotherapy","score":0.9309999942779541},{"id":"https://openalex.org/keywords/beam-weight-optimization","display_name":"beam weight optimization","score":0.7889999747276306},{"id":"https://openalex.org/keywords/beam-angle-optimization","display_name":"beam angle optimization","score":0.9549999833106995},{"id":"https://openalex.org/keywords/normal-tissue-dose-constraints","display_name":"normal tissue dose constraints","score":0.7039999961853027},{"id":"https://openalex.org/keywords/treatment-planning","display_name":"treatment planning","score":0.492000013589859}],"concepts":[{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.7072779536247253},{"id":"https://openalex.org/C98214594","wikidata":"https://www.wikidata.org/wiki/Q850275","display_name":"Conformal map","level":2,"score":0.6793931126594543},{"id":"https://openalex.org/C41045048","wikidata":"https://www.wikidata.org/wiki/Q202843","display_name":"Linear programming","level":2,"score":0.6468402147293091},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.5258346796035767},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.5141768455505371},{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.4580700397491455},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.44529420137405396},{"id":"https://openalex.org/C2776036281","wikidata":"https://www.wikidata.org/wiki/Q48769818","display_name":"Constraint (computer-aided design)","level":2,"score":0.4229947626590729},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4007093012332916},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.39015859365463257},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.1649894118309021},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.14821943640708923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13251638412475586},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.09700024127960205},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.08620131015777588},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011382","descriptor_name":"Programming, Linear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1118/1.596592","doi":"https://doi.org/10.1118/1.596592","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.596592","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},{"id":"pmid:1753905","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1753905","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical physics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8412867100","display_name":"CONFORMAL RADIATION THERAPY TREATMENT PLAN OPTIMIZATION","funder_award_id":"R01CA046634","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2530641023","https://openalex.org/W2012351471","https://openalex.org/W2035111930","https://openalex.org/W2047588216","https://openalex.org/W2287740599","https://openalex.org/W1979800170","https://openalex.org/W4405139287","https://openalex.org/W2016389837","https://openalex.org/W4361771776","https://openalex.org/W2128830305"],"abstract_inverted_index":{"A":[0],"method":[1,16],"of":[2,9,22,51,66],"incorporating":[3],"dose-volume":[4,117],"considerations":[5],"within":[6],"the":[7,20,34,38,47,55,71,115],"framework":[8],"conventional":[10],"linear":[11,126,137],"programming":[12,127,138],"is":[13,17,78,133],"presented.":[14],"This":[15],"suitable":[18],"for":[19,104,119],"optimization":[21],"beam":[23],"weights":[24],"and":[25,82],"angles":[26],"using":[27,46,124],"a":[28,120,129],"conformal":[29],"treatment":[30,102,122],"philosophy":[31],"(i.e.,":[32],"tailoring":[33],"high-dose":[35,81,96],"region":[36],"to":[37,70,135],"target":[39,56,72],"volume":[40,57,87],"only).":[41],"Dose-volume":[42],"constraints":[43,63,118],"are":[44,89],"introduced":[45],"concept":[48],"that":[49,109,132],"volumes":[50,65],"normal":[52,67,76],"tissue":[53,68],"nearer":[54],"will":[58],"be":[59],"allowed":[60],"higher":[61],"dose":[62],"than":[64],"distal":[69],"volume.":[73],"Each":[74],"involved":[75],"structure":[77],"divided":[79],"into":[80],"low-dose":[83,98],"volumes.":[84],"These":[85],"two":[86],"partitions":[88],"represented":[90],"by":[91],"constraint":[92],"points":[93],"with":[94],"either":[95],"or":[97,113],"constraints,":[99],"respectively.":[100],"Optimized":[101],"plans":[103],"three":[105],"clinical":[106],"sites":[107],"demonstrate":[108],"this":[110],"technique":[111],"meets":[112],"surpasses":[114],"original":[116],"conformal-type":[121],"plan":[123],"straightforward":[125],"in":[128],"time":[130],"frame":[131],"comparable":[134],"other":[136],"problems.":[139]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}