{"id":"https://openalex.org/W2000667564","doi":"https://doi.org/10.1159/000262367","title":"Relationship between Caries and Level of Metabolic Balance in Children and Adolescents with Insulin-Dependent Diabetes mellitus","display_name":"Relationship between Caries and Level of Metabolic Balance in Children and Adolescents with Insulin-Dependent Diabetes mellitus","publication_year":2009,"publication_date":"2009-11-24","ids":{"openalex":"https://openalex.org/W2000667564","doi":"https://doi.org/10.1159/000262367","mag":"2000667564","pmid":"https://pubmed.ncbi.nlm.nih.gov/8955988"},"language":"en","primary_location":{"id":"doi:10.1159/000262367","doi":"https://doi.org/10.1159/000262367","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000262367","pdf_url":null,"source":{"id":"https://openalex.org/S23327923","display_name":"Caries Research","issn_l":"0008-6568","issn":["0008-6568","1421-976X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076928570","display_name":"Kaisa M. Karjalainen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405277888","display_name":"Institute of Dentistry","ror":"https://ror.org/046v0bc89","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4405277888"]},{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI","TH"],"is_corresponding":false,"raw_author_name":"K.M. Karjalainen","raw_affiliation_strings":["Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, University of Oulu, Finland","Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, University of Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, and","institution_ids":["https://openalex.org/I4405277888"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045198416","display_name":"Matias Knuuttila","orcid":"https://orcid.org/0000-0002-9953-5755","observed_orcids":["https://orcid.org/0000-0002-9953-5755"]},"institutions":[{"id":"https://openalex.org/I2799272722","display_name":"Oulu University Hospital","ror":"https://ror.org/045ney286","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2799272722"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"M.L.E. Knuuttila","raw_affiliation_strings":["Oral and Maxillofacial Department, Oulu University Hospital, Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oral and Maxillofacial Department, Oulu University Hospital, Oulu, Finland","institution_ids":["https://openalex.org/I2799272722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026348027","display_name":"M.-L. K\u00e4\u00e4r","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"M.-L. K\u00e4\u00e4r","raw_affiliation_strings":["Department of Pediatrics, University of Oulu, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Oulu, and","institution_ids":["https://openalex.org/I98381234"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.7369,"has_fulltext":false,"cited_by_count":86,"citation_normalized_percentile":{"value":0.95766791,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"31","issue":"1","first_page":"13","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.1615999937057495,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.02329999953508377,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.9639999866485596},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9369999766349792},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7540000081062317},{"id":"https://openalex.org/keywords/glycosylated-haemoglobin","display_name":"glycosylated haemoglobin","score":0.968999981880188},{"id":"https://openalex.org/keywords/caries-risk-indicators","display_name":"caries risk indicators","score":0.6679999828338623},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.7710000276565552},{"id":"https://openalex.org/keywords/salivary-lactobacilli","display_name":"salivary lactobacilli","score":0.7720000147819519},{"id":"https://openalex.org/keywords/streptococcus-mutans","display_name":"Streptococcus mutans","score":0.9169999957084656},{"id":"https://openalex.org/keywords/salivary-buffering-capacity","display_name":"salivary buffering capacity","score":0.7450000047683716}],"concepts":[{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6574537754058838},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6565459966659546},{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.5778480768203735},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5514050722122192},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4405127465724945},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3835923671722412},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3423445224761963},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.14966616034507751}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D003732","descriptor_name":"Dental Caries Activity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004245","descriptor_name":"DMF Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007778","descriptor_name":"Lactobacillus","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013295","descriptor_name":"Streptococcus mutans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000262367","doi":"https://doi.org/10.1159/000262367","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000262367","pdf_url":null,"source":{"id":"https://openalex.org/S23327923","display_name":"Caries Research","issn_l":"0008-6568","issn":["0008-6568","1421-976X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries Research","raw_type":"journal-article"},{"id":"pmid:8955988","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8955988","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caries research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2141902876","https://openalex.org/W2020612793","https://openalex.org/W2054537407","https://openalex.org/W4400368769","https://openalex.org/W2121404725","https://openalex.org/W2440154903","https://openalex.org/W1531316978","https://openalex.org/W4399041933","https://openalex.org/W1984632410","https://openalex.org/W1977354209"],"abstract_inverted_index":{"The":[0,20,255],"relationship":[1],"between":[2,155,223],"the":[3,24,70,84,150,159,174,196,224],"occurrence":[4],"of":[5,23,34,86,90,124,126,145,152,161,176,179,187,199,246,257],"caries":[6,98,262],"and":[7,14,32,88,105,147,158,189,212,218,233],"diabetes":[8,18,35,87,91,125,146,170,247,270],"was":[9,26,72,138,164,171,181,248],"explored":[10],"in":[11,43,57,62,167,195,265],"80":[12],"children":[13],"adolescents":[15],"with":[16,97,111,120,184,201,253,267],"insulin-dependent":[17],"mellitus.":[19],"mean":[21],"age":[22,82,148,175],"subjects":[25,46,110,117,119,168,200,235,266],"14.5":[27],"years":[28,37],"(range":[29],"11.7-18.4":[30],"years)":[31],"duration":[33,89,144],"0.3-15.0":[36],"(mean":[38],"6.0":[39],"years).":[40],"DFS":[41],"indices":[42],"poorly":[44,277],"controlled":[45],"(glycosylated":[47],"haemoglobin,":[48],"HbA1,":[49],"values":[50,66,108],"over":[51],"13%)":[52],"were":[53,78,134,191,220,231],"significantly":[54,102],"higher":[55,103],"than":[56,109],"moderately":[58],"(HbA1":[59,65],"10.0-12.9%)":[60],"or":[61,118],"well-controlled":[63],"cases":[64],"<":[67],"10%).":[68],"However,":[69],"difference":[71],"not":[73,221],"statistically":[74],"significant":[75],"if":[76,115,276],"adjustments":[77,141],"made":[79],"for":[80,142],"age,":[81,143],"at":[83,127,149],"onset":[85,151],"(p":[92],"=":[93,132],"0.1,":[94],"Ancova).":[95],"Subjects":[96],"and/or":[99,203],"fillings":[100],"had":[101,236],"short-":[104],"long-term":[106,121],"HbA1":[107],"intact":[112,162],"teeth,":[113],"both":[114],"all":[116,234],"disease":[122],"(duration":[123],"least":[128],"2":[129],"years,":[130],"n":[131],"62)":[133],"included.":[135],"This":[136],"finding":[137],"valid":[139],"after":[140],"diabetes.":[153],"Association":[154],"poor":[156,185,244],"control":[157,186,245],"loss":[160],"dentition":[163],"also":[165],"demonstrated":[166],"whose":[169],"diagnosed":[172],"before":[173],"7.":[177],"Presence":[178],"yeasts":[180,190,258],"highly":[182],"associated":[183,252],"diabetes,":[188,268],"more":[192],"frequently":[193],"found":[194,249],"saliva":[197],"samples":[198],"decayed":[202],"filled":[204],"teeth.":[205],"Instead,":[206],"salivary":[207,210],"flow":[208],"rates,":[209],"lactobacilli":[211],"Streptococcus":[213],"mutans":[214],"counts,":[215],"buffering":[216],"capacity":[217],"pH":[219],"different":[222],"subjects.":[225],"As":[226],"well,":[227],"home":[228],"care":[229],"practices":[230],"similar,":[232],"received":[237],"similar":[238],"regular":[239],"dental":[240],"treatment.":[241],"In":[242],"conclusion,":[243],"to":[250],"be":[251,260],"caries.":[254],"presence":[256],"may":[259,271],"a":[261],"risk":[263],"indicator":[264],"since":[269],"enhance":[272],"yeast":[273],"growth,":[274],"particularly":[275],"controlled.":[278]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}