{"id":"https://openalex.org/W2000656402","doi":"https://doi.org/10.1136/emermed-2012-202101","title":"Association of out-of-hospital advanced airway management with outcomes after traumatic brain injury and hemorrhagic shock in the ROC hypertonic saline trial","display_name":"Association of out-of-hospital advanced airway management with outcomes after traumatic brain injury and hemorrhagic shock in the ROC hypertonic saline trial","publication_year":2013,"publication_date":"2013-01-26","ids":{"openalex":"https://openalex.org/W2000656402","doi":"https://doi.org/10.1136/emermed-2012-202101","mag":"2000656402","pmid":"https://pubmed.ncbi.nlm.nih.gov/23353663","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3841245"},"language":"en","primary_location":{"id":"doi:10.1136/emermed-2012-202101","doi":"https://doi.org/10.1136/emermed-2012-202101","is_oa":false,"landing_page_url":"https://doi.org/10.1136/emermed-2012-202101","pdf_url":null,"source":{"id":"https://openalex.org/S127305661","display_name":"Emergency Medicine Journal","issn_l":"1351-0622","issn":["1351-0622","1472-0205","1472-0213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Emergency Medicine Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3841245","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026192603","display_name":"Henry E. Wang","orcid":"https://orcid.org/0000-0002-4738-0093","observed_orcids":["https://orcid.org/0000-0002-4738-0093"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Henry E Wang","raw_affiliation_strings":["Department of Emergency Medicine, University of Alabama School of Medicine, , Birmingham, Albama, USA","Department of Emergency Medicine, University of Alabama at Birmingham, 619 19th Street South, OHB 251, Birmingham, AL 35249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Alabama School of Medicine, , Birmingham, Albama, USA","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Department of Emergency Medicine, University of Alabama at Birmingham, 619 19th Street South, OHB 251, Birmingham, AL 35249, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069653611","display_name":"Siobhan P. Brown","orcid":"https://orcid.org/0000-0002-4774-3122","observed_orcids":["https://orcid.org/0000-0002-4774-3122"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Siobhan P Brown","raw_affiliation_strings":["Department of Biostatistics, The Clinical Trials Center, University of Washington, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, The Clinical Trials Center, University of Washington, Seattle, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008807307","display_name":"Russell D. MacDonald","orcid":"https://orcid.org/0000-0001-6938-3925","observed_orcids":["https://orcid.org/0000-0001-6938-3925"]},"institutions":[{"id":"https://openalex.org/I1297363086","display_name":"St. Michael's Hospital","ror":"https://ror.org/04skqfp25","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1297363086","https://openalex.org/I4399598460"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4405268199","display_name":"Ornge","ror":"https://ror.org/0062vp887","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4405268199"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Russell D MacDonald","raw_affiliation_strings":["Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Rescu, Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada","Ornge Transport Medicine, Mississauga, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Rescu, Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1297363086","https://openalex.org/I185261750"]},{"raw_affiliation_string":"Ornge Transport Medicine, Mississauga, Ontario, Canada","institution_ids":["https://openalex.org/I4405268199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056578154","display_name":"Shawn K. Dowling","orcid":"https://orcid.org/0000-0002-6378-7299","observed_orcids":["https://orcid.org/0000-0002-6378-7299"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Shawn K Dowling","raw_affiliation_strings":["Department of Emergency Medicine, University of Calgary, Calgary, Alberta, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Calgary, Calgary, Alberta, Canada","institution_ids":["https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025928819","display_name":"Steve Lin","orcid":"https://orcid.org/0000-0002-8644-9719","observed_orcids":["https://orcid.org/0000-0002-8644-9719"]},"institutions":[{"id":"https://openalex.org/I1297363086","display_name":"St. Michael's Hospital","ror":"https://ror.org/04skqfp25","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1297363086","https://openalex.org/I4399598460"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Steve Lin","raw_affiliation_strings":["Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Rescu, Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Rescu, Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1297363086","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043647963","display_name":"Daniel P. Davis","orcid":"https://orcid.org/0000-0001-6681-9471","observed_orcids":["https://orcid.org/0000-0001-6681-9471"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Davis","raw_affiliation_strings":["Department of Emergency Medicine, University of California at San Diego, San Diego, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of California at San Diego, San Diego, California, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102860136","display_name":"Martin A. Schreiber","orcid":"https://orcid.org/0000-0002-4430-6779","observed_orcids":["https://orcid.org/0000-0002-4430-6779"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin A Schreiber","raw_affiliation_strings":["Department of Surgery, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, Portland, Oregon, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, Portland, Oregon, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108514315","display_name":"Judy L. Powell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judy Powell","raw_affiliation_strings":["Department of Biostatistics, The Clinical Trials Center, University of Washington, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, The Clinical Trials Center, University of Washington, Seattle, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074880146","display_name":"Rardi van Heest","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13328022","display_name":"Royal Columbian Hospital","ror":"https://ror.org/05ymyxj51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1308729876","https://openalex.org/I13328022","https://openalex.org/I178133122"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rardi van Heest","raw_affiliation_strings":["Trauma Services, Royal Columbian Hospital, Vancouver, British Columbia, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trauma Services, Royal Columbian Hospital, Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I13328022"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027261693","display_name":"Mohamud Ramzan Daya","orcid":"https://orcid.org/0000-0002-6910-8293","observed_orcids":["https://orcid.org/0000-0002-6910-8293"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamud Daya","raw_affiliation_strings":["Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon, USA","institution_ids":["https://openalex.org/I165690674"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5026192603"],"corresponding_institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"],"apc_list":null,"apc_paid":null,"fwci":3.5695,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.92486188,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"31","issue":"3","first_page":"186","last_page":"191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11467","display_name":"Trauma and Emergency Care Studies","score":0.38499999046325684,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11467","display_name":"Trauma and Emergency Care Studies","score":0.38499999046325684,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.3644999861717224,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.12489999830722809,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.9430000185966492},{"id":"https://openalex.org/keywords/hemorrhagic-shock","display_name":"hemorrhagic shock","score":0.9070000052452087},{"id":"https://openalex.org/keywords/28-day-mortality","display_name":"28-day mortality","score":0.8730000257492065},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.8880000114440918},{"id":"https://openalex.org/keywords/neurological-outcome","display_name":"neurological outcome","score":0.9710000157356262},{"id":"https://openalex.org/keywords/emergency-department-airway-management","display_name":"emergency department airway management","score":0.746999979019165},{"id":"https://openalex.org/keywords/resuscitation-outcomes-consortium","display_name":"Resuscitation Outcomes Consortium","score":0.718999981880188},{"id":"https://openalex.org/keywords/hypertonic-saline","display_name":"hypertonic saline","score":0.7799999713897705},{"id":"https://openalex.org/keywords/severe-trauma","display_name":"severe trauma","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9706199765205383},{"id":"https://openalex.org/C3017567848","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Hypertonic saline","level":2,"score":0.9044123888015747},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.6914275288581848},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.5498849153518677},{"id":"https://openalex.org/C2993366118","wikidata":"https://www.wikidata.org/wiki/Q1320276","display_name":"Hemorrhagic shock","level":3,"score":0.5333822965621948},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5258810520172119},{"id":"https://openalex.org/C2780978852","wikidata":"https://www.wikidata.org/wiki/Q286949","display_name":"Airway management","level":3,"score":0.48670509457588196},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.4707299470901489},{"id":"https://openalex.org/C2778165595","wikidata":"https://www.wikidata.org/wiki/Q5491454","display_name":"Resuscitation","level":2,"score":0.4507867097854614},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.4331662058830261},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3528349995613098},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07601821422576904}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001930","descriptor_name":"Brain Injuries","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001930","descriptor_name":"Brain Injuries","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004632","descriptor_name":"Emergency Medical Services","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012771","descriptor_name":"Shock, Hemorrhagic","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012771","descriptor_name":"Shock, Hemorrhagic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017052","descriptor_name":"Hospital Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017063","descriptor_name":"Outcome Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039602","descriptor_name":"After-Hours Care","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D058109","descriptor_name":"Airway Management","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1136/emermed-2012-202101","doi":"https://doi.org/10.1136/emermed-2012-202101","is_oa":false,"landing_page_url":"https://doi.org/10.1136/emermed-2012-202101","pdf_url":null,"source":{"id":"https://openalex.org/S127305661","display_name":"Emergency Medicine Journal","issn_l":"1351-0622","issn":["1351-0622","1472-0205","1472-0213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Emergency Medicine Journal","raw_type":"journal-article"},{"id":"pmid:23353663","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23353663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Emergency medicine journal : EMJ","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3309157","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3841245","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3841245","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3841245/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Emerg Med J","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:emermed:31/3/186","doi":null,"is_oa":false,"landing_page_url":"http://emj.bmj.com/cgi/content/short/31/3/186","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3309157","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3841245","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G15146305","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Seattle-King","funder_award_id":"U01HL077867","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2012890928","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Alabama","funder_award_id":"U01HL077881","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3098151525","display_name":"Resuscitation Outcomes Consortium Regional Clinical Center-DFW Center for Resusci","funder_award_id":"U01HL077887","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3108119593","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Pittsburgh","funder_award_id":"U01HL077871","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4425193450","display_name":null,"funder_award_id":"HL077871","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4515682498","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Centers-Milwaukee","funder_award_id":"U01HL077866","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5013845593","display_name":"Resuscitation Outcomes Consortium (ROC) Data Coordinating Center","funder_award_id":"U01HL077863","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6113346695","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Portland","funder_award_id":"U01HL077873","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8052683381","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Toronto Regional","funder_award_id":"U01HL077872","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8063220447","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center, San Diego","funder_award_id":"U01HL077908","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8933601267","display_name":"Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-OTTAWA-OPALS-BCR","funder_award_id":"U01HL077885","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W100082401","https://openalex.org/W1552661887","https://openalex.org/W1964545630","https://openalex.org/W1970527702","https://openalex.org/W1972631780","https://openalex.org/W1981011172","https://openalex.org/W1983474047","https://openalex.org/W1987475835","https://openalex.org/W2005912293","https://openalex.org/W2009019517","https://openalex.org/W2013655618","https://openalex.org/W2042265613","https://openalex.org/W2045498748","https://openalex.org/W2048828214","https://openalex.org/W2059058279","https://openalex.org/W2070586748","https://openalex.org/W2084962044","https://openalex.org/W2085420740","https://openalex.org/W2087872052","https://openalex.org/W2114860810","https://openalex.org/W2116758029","https://openalex.org/W2118502261","https://openalex.org/W2120067680","https://openalex.org/W2126969787","https://openalex.org/W2161444192","https://openalex.org/W2164315467"],"related_works":["https://openalex.org/W2114061070","https://openalex.org/W1983811066","https://openalex.org/W2067243860","https://openalex.org/W2344095083","https://openalex.org/W4396777431","https://openalex.org/W4296071601","https://openalex.org/W2048828214","https://openalex.org/W1966941254","https://openalex.org/W3168617706","https://openalex.org/W3173187470"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Prior":[1],"studies":[2],"suggest":[3],"adverse":[4,243],"associations":[5,32,93],"between":[6,33,94,245],"out-of-hospital":[7,34,82,166,184,246],"advanced":[8],"airway":[9,95,110],"management":[10],"(AAM)":[11],"and":[12,36,73,97,102,109,125,144,201,248],"patient":[13,98],"outcomes":[14,37,99],"after":[15,239],"major":[16],"trauma.":[17],"This":[18,51],"secondary":[19],"analysis":[20],"of":[21],"data":[22],"from":[23],"the":[24,92,152,163],"Resuscitation":[25],"Outcomes":[26],"Consortium":[27],"Hypertonic":[28],"Saline":[29],"Trial":[30],"evaluated":[31,91],"AAM":[35,83,157,167,185,218,233,247],"in":[38,151,254],"patients":[39,80,120,127,255],"suffering":[40],"isolated":[41,122],"severe":[42,57,123,134],"traumatic":[43],"brain":[44],"injury":[45,249],"(TBI)":[46],"or":[47,61,68,106,132,158],"haemorrhagic":[48,62,129,240,257],"shock.":[49,241,258],"METHODS:":[50],"multicentre":[52],"study":[53],"included":[54],"adults":[55],"with":[56,84,121,128,131,170,221,236,256],"TBI":[58,124,143,224],"(GCS":[59],"\u22648)":[60],"shock":[63,130,164],"(SBP":[64,69],"\u226470":[65],"mm":[66,71],"Hg,":[67],"71-90":[70],"Hg":[72],"heart":[74],"rate":[75],"\u2265108":[76],"bpm)).":[77],"We":[78,90],"compared":[79],"receiving":[81,86],"those":[85],"emergency":[87],"department":[88],"AAM.":[89],"strategy":[96],"(28-day":[100],"mortality,":[101],"6-month":[103,202,223],"poor":[104,203],"neurologic":[105,225],"functional":[107,204],"outcome)":[108],"strategy,":[111],"adjusting":[112],"for":[113],"confounders.":[114],"Analysis":[115],"was":[116,168,219,234],"stratified":[117],"by":[118],"(1)":[119],"(2)":[126],"without":[133],"TBI.":[135],"RESULTS:":[136],"Of":[137],"2135":[138],"patients,":[139],"we":[140],"studied":[141],"1116":[142],"528":[145],"shock;":[146],"excluding":[147],"491":[148],"who":[149],"died":[150],"field,":[153],"did":[154],"not":[155,214],"receive":[156],"had":[159],"missing":[160],"data.":[161],"In":[162,182],"cohort,":[165],"associated":[169,220,235],"increased":[171,190,237],"28-day":[172,191],"mortality":[173,192,238],"(adjusted":[174,193],"OR":[175,194],"5.14;":[176],"95%":[177,196],"CI":[178,197],"2.42":[179],"to":[180,199,208,229],"10.90).":[181],"TBI,":[183],"showed":[186],"a":[187],"tendency":[188],"towards":[189],"1.57;":[195],"0.93":[198],"2.64)":[200],"outcome":[205,226,250],"(1.63;":[206],"1.00":[207],"2.68),":[209],"but":[210],"these":[211],"differences":[212],"were":[213],"statistically":[215],"significant.":[216],"Out-of-hospital":[217,232],"poorer":[222],"(1.80;":[227],"1.09":[228],"2.96).":[230],"CONCLUSIONS:":[231],"The":[242],"association":[244],"is":[251],"most":[252],"pronounced":[253]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}