{"id":"https://openalex.org/W2000644415","doi":"https://doi.org/10.1016/0165-5728(90)90105-v","title":"Elevation of tumor necrosis factor in head injury","display_name":"Elevation of tumor necrosis factor in head injury","publication_year":1990,"publication_date":"1990-12-01","ids":{"openalex":"https://openalex.org/W2000644415","doi":"https://doi.org/10.1016/0165-5728(90)90105-v","mag":"2000644415","pmid":"https://pubmed.ncbi.nlm.nih.gov/2229409"},"language":"en","primary_location":{"id":"doi:10.1016/0165-5728(90)90105-v","doi":"https://doi.org/10.1016/0165-5728(90)90105-v","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-5728(90)90105-v","pdf_url":null,"source":{"id":"https://openalex.org/S137419829","display_name":"Journal of Neuroimmunology","issn_l":"0165-5728","issn":["0165-5728","1872-8421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroimmunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110202841","display_name":"Jerry Clay Goodman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. Clay Goodman","raw_affiliation_strings":["Department of Pathology, Baylor College of Medicine, Houston, TX 77030","Department of Pathology, Baylor College of Medicine, Houston, TX 77030, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Baylor College of Medicine, Houston, TX 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Pathology, Baylor College of Medicine, Houston, TX 77030, U.S.A","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072957881","display_name":"Claudia Sue Robertson","orcid":"https://orcid.org/0000-0002-8509-678X","observed_orcids":["https://orcid.org/0000-0002-8509-678X"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia S. Robertson","raw_affiliation_strings":["Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054255550","display_name":"Robert G. Grossman","orcid":"https://orcid.org/0000-0001-7006-7612","observed_orcids":["https://orcid.org/0000-0001-7006-7612"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert G. Grossman","raw_affiliation_strings":["Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049650232","display_name":"Raj K. Narayan","orcid":"https://orcid.org/0000-0002-5587-8430","observed_orcids":["https://orcid.org/0000-0002-5587-8430"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raj K. Narayan","raw_affiliation_strings":["Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, U.S.A","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110202841"],"corresponding_institution_ids":["https://openalex.org/I181547552"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":1.6458,"has_fulltext":false,"cited_by_count":224,"citation_normalized_percentile":{"value":0.83754619,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"30","issue":"2-3","first_page":"213","last_page":"217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.538100004196167,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.538100004196167,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.3244999945163727,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.01850000023841858,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":1.0},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.9430000185966492},{"id":"https://openalex.org/keywords/urinary-nitrogen-excretion","display_name":"urinary nitrogen excretion","score":0.8629999756813049},{"id":"https://openalex.org/keywords/nitrogen-balance","display_name":"nitrogen balance","score":0.9940000176429749},{"id":"https://openalex.org/keywords/serum-tnf-levels","display_name":"serum TNF levels","score":0.6779999732971191},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.7620000243186951},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.765999972820282}],"concepts":[{"id":"https://openalex.org/C37054046","wikidata":"https://www.wikidata.org/wiki/Q641888","display_name":"Elevation (ballistics)","level":2,"score":0.5698510408401489},{"id":"https://openalex.org/C2780312720","wikidata":"https://www.wikidata.org/wiki/Q5689100","display_name":"Head (geology)","level":2,"score":0.5464563965797424},{"id":"https://openalex.org/C2777975874","wikidata":"https://www.wikidata.org/wiki/Q2920572","display_name":"Head injury","level":2,"score":0.5265227556228638},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44650956988334656},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.4376608431339264},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3444802761077881},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.1954023838043213},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1492561399936676},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10466039180755615},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.05553886294364929},{"id":"https://openalex.org/C114793014","wikidata":"https://www.wikidata.org/wiki/Q52109","display_name":"Geomorphology","level":1,"score":0.04121601581573486}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001930","descriptor_name":"Brain Injuries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001930","descriptor_name":"Brain Injuries","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009584","descriptor_name":"Nitrogen","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0165-5728(90)90105-v","doi":"https://doi.org/10.1016/0165-5728(90)90105-v","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-5728(90)90105-v","pdf_url":null,"source":{"id":"https://openalex.org/S137419829","display_name":"Journal of Neuroimmunology","issn_l":"0165-5728","issn":["0165-5728","1872-8421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroimmunology","raw_type":"journal-article"},{"id":"pmid:2229409","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2229409","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroimmunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G7828953750","display_name":null,"funder_award_id":"NS27616","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W58299579","https://openalex.org/W178972958","https://openalex.org/W1832124212","https://openalex.org/W1904020067","https://openalex.org/W1928849416","https://openalex.org/W1938685687","https://openalex.org/W2013114215","https://openalex.org/W2014444795","https://openalex.org/W2019478152","https://openalex.org/W2025392129","https://openalex.org/W2040179836","https://openalex.org/W2048540725","https://openalex.org/W2072486140","https://openalex.org/W2072863715","https://openalex.org/W2097395571","https://openalex.org/W2118872783","https://openalex.org/W2125370809","https://openalex.org/W2126342903","https://openalex.org/W2131115069","https://openalex.org/W2161345233","https://openalex.org/W2164180269","https://openalex.org/W2168835648","https://openalex.org/W2170992825","https://openalex.org/W2174322658","https://openalex.org/W2323870293","https://openalex.org/W2338212033","https://openalex.org/W2410325753"],"related_works":["https://openalex.org/W2279702325","https://openalex.org/W1966969529","https://openalex.org/W2353232151","https://openalex.org/W2347901459","https://openalex.org/W2374113376","https://openalex.org/W2104423158","https://openalex.org/W2377441409","https://openalex.org/W2400911264","https://openalex.org/W2060298644","https://openalex.org/W2388479816"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}