{"id":"https://openalex.org/W2000643966","doi":"https://doi.org/10.1007/s00018-012-1160-9","title":"Extensive characterization of sphere models established from colorectal cancer cell lines","display_name":"Extensive characterization of sphere models established from colorectal cancer cell lines","publication_year":2012,"publication_date":"2012-09-24","ids":{"openalex":"https://openalex.org/W2000643966","doi":"https://doi.org/10.1007/s00018-012-1160-9","mag":"2000643966","pmid":"https://pubmed.ncbi.nlm.nih.gov/23007843","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11113113"},"language":"en","primary_location":{"id":"doi:10.1007/s00018-012-1160-9","doi":"https://doi.org/10.1007/s00018-012-1160-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00018-012-1160-9","pdf_url":null,"source":{"id":"https://openalex.org/S60362788","display_name":"Cellular and Molecular Life Sciences","issn_l":"1420-682X","issn":["1420-682X","1420-9071"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11113113","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024751330","display_name":"Ada Collura","orcid":"https://orcid.org/0000-0003-0496-1768","observed_orcids":["https://orcid.org/0000-0003-0496-1768"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Ada Collura","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \"Instabilit\u00e9 des Microsatellites et Cancers\", 75012, Paris, France. ada.collura@inserm.fr","Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \"Instabilit\u00e9 des Microsatellites et Cancers\", 75012, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \"Instabilit\u00e9 des Microsatellites et Cancers\", 75012, Paris, France. ada.collura@inserm.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \"Instabilit\u00e9 des Microsatellites et Cancers\", 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081199992","display_name":"La\u00ebtitia Marisa","orcid":"https://orcid.org/0000-0001-5529-7217","observed_orcids":["https://orcid.org/0000-0001-5529-7217"]},"institutions":[{"id":"https://openalex.org/I4210095243","display_name":"La Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210095243"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laetitia Marisa","raw_affiliation_strings":["Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France","institution_ids":["https://openalex.org/I4210095243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030838370","display_name":"Diletta Trojan","orcid":"https://orcid.org/0000-0002-9003-9421","observed_orcids":["https://orcid.org/0000-0002-9003-9421"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Diletta Trojan","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035282335","display_name":"Olivier Buhard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Olivier Buhard","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073965148","display_name":"Ana\u00efs Lagrange","orcid":"https://orcid.org/0009-0007-2766-0729","observed_orcids":["https://orcid.org/0009-0007-2766-0729"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ana\u00efs Lagrange","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110052689","display_name":"Arnaud Saget","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Arnaud Saget","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049103100","display_name":"Marianne Bombled","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102197404","display_name":"Universit\u00e9 Paris-Sud","ror":"https://ror.org/028rypz17","country_code":"FR","type":"education","lineage":["https://openalex.org/I102197404","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4405260426","display_name":"Conception, synth\u00e8se et vectorisation de biomol\u00e9cules","ror":"https://ror.org/03r1pw664","country_code":"FR","type":"facility","lineage":["https://openalex.org/I204730241","https://openalex.org/I4405260426"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marianne Bombled","raw_affiliation_strings":["UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France","institution_ids":["https://openalex.org/I102197404","https://openalex.org/I1294671590","https://openalex.org/I4405260426","https://openalex.org/I80043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057414643","display_name":"Patricia M\u00e9chighel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Patricia M\u00e9chighel","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002879400","display_name":"Mira Ayadi","orcid":"https://orcid.org/0000-0002-4019-2858","observed_orcids":["https://orcid.org/0000-0002-4019-2858"]},"institutions":[{"id":"https://openalex.org/I4210095243","display_name":"La Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210095243"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mira Ayadi","raw_affiliation_strings":["Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France","institution_ids":["https://openalex.org/I4210095243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002162334","display_name":"Martine Muleris","orcid":"https://orcid.org/0000-0002-6009-5529","observed_orcids":["https://orcid.org/0000-0002-6009-5529"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Martine Muleris","raw_affiliation_strings":["Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042627121","display_name":"Aur\u00e9lien de Reyni\u00e8s","orcid":"https://orcid.org/0000-0002-1328-5290","observed_orcids":["https://orcid.org/0000-0002-1328-5290"]},"institutions":[{"id":"https://openalex.org/I4210095243","display_name":"La Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210095243"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aur\u00e9lien de Reynies","raw_affiliation_strings":["Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programme \u201cCartes d\u2019Identit\u00e9 des Tumeurs\u201d, Ligue Nationale Contre le Cancer, Paris, France","institution_ids":["https://openalex.org/I4210095243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010902289","display_name":"Magali Svrcek","orcid":"https://orcid.org/0000-0001-9023-5791","observed_orcids":["https://orcid.org/0000-0001-9023-5791"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Magali Svrcek","raw_affiliation_strings":["AP-HP, H\u00f4pital Saint-Antoine, Service d\u2019Anatomie et Cytologie Pathologiques, Paris, France","AP-HP, H\u00f4pital Saint-Antoine, Tumoroth\u00e8que CancerEst, 75012, Paris, France","Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, H\u00f4pital Saint-Antoine, Service d\u2019Anatomie et Cytologie Pathologiques, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"AP-HP, H\u00f4pital Saint-Antoine, Tumoroth\u00e8que CancerEst, 75012, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084448152","display_name":"Jean\u2013Fran\u00e7ois Fl\u00e9jou","orcid":"https://orcid.org/0000-0002-4971-2434","observed_orcids":["https://orcid.org/0000-0002-4971-2434"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Fran\u00e7ois Fl\u00e9jou","raw_affiliation_strings":["AP-HP, H\u00f4pital Saint-Antoine, Service d\u2019Anatomie et Cytologie Pathologiques, Paris, France","AP-HP, H\u00f4pital Saint-Antoine, Tumoroth\u00e8que CancerEst, 75012, Paris, France","Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, H\u00f4pital Saint-Antoine, Service d\u2019Anatomie et Cytologie Pathologiques, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"AP-HP, H\u00f4pital Saint-Antoine, Tumoroth\u00e8que CancerEst, 75012, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016706372","display_name":"Jean\u2010Claude Florent","orcid":"https://orcid.org/0000-0001-9837-5094","observed_orcids":["https://orcid.org/0000-0001-9837-5094"]},"institutions":[{"id":"https://openalex.org/I102197404","display_name":"Universit\u00e9 Paris-Sud","ror":"https://ror.org/028rypz17","country_code":"FR","type":"education","lineage":["https://openalex.org/I102197404","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4405260426","display_name":"Conception, synth\u00e8se et vectorisation de biomol\u00e9cules","ror":"https://ror.org/03r1pw664","country_code":"FR","type":"facility","lineage":["https://openalex.org/I204730241","https://openalex.org/I4405260426"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Claude Florent","raw_affiliation_strings":["UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France","institution_ids":["https://openalex.org/I102197404","https://openalex.org/I1294671590","https://openalex.org/I4405260426","https://openalex.org/I80043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086244580","display_name":"Florence Mahuteau\u2010Betzer","orcid":"https://orcid.org/0000-0002-3009-252X","observed_orcids":["https://orcid.org/0000-0002-3009-252X"]},"institutions":[{"id":"https://openalex.org/I102197404","display_name":"Universit\u00e9 Paris-Sud","ror":"https://ror.org/028rypz17","country_code":"FR","type":"education","lineage":["https://openalex.org/I102197404","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4405260426","display_name":"Conception, synth\u00e8se et vectorisation de biomol\u00e9cules","ror":"https://ror.org/03r1pw664","country_code":"FR","type":"facility","lineage":["https://openalex.org/I204730241","https://openalex.org/I4405260426"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florence Mahuteau-Betzer","raw_affiliation_strings":["UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMR 176 CNRS/Institut Curie, Universite Paris-Sud, Orsay, France","institution_ids":["https://openalex.org/I102197404","https://openalex.org/I1294671590","https://openalex.org/I4405260426","https://openalex.org/I80043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018804969","display_name":"Anne\u2010Marie Faussat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne-Marie Faussat","raw_affiliation_strings":["Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038592146","display_name":"Alex Duval","orcid":"https://orcid.org/0000-0003-1534-1724","observed_orcids":["https://orcid.org/0000-0003-1534-1724"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Alex Duval","raw_affiliation_strings":["INSERM UMRS 938 Team \u201cMicrosatellite Instability and Cancer\u201d, H\u00f4pital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75571, Paris cedex 12, France","Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM UMRS 938 Team \u201cMicrosatellite Instability and Cancer\u201d, H\u00f4pital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75571, Paris cedex 12, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Inserm, UMRS_938, Centre de Recherche Saint-Antoine, Equipe \u201cInstabilit\u00e9 des Microsatellites et Cancers\u201d, 75012, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210134622"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie-Paris6, Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5024751330","https://openalex.org/A5038592146"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4210134622","https://openalex.org/I4405264447"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":null,"fwci":1.7999,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.84447445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"70","issue":"4","first_page":"729","last_page":"742"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.953000009059906},{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/sphere-culture","display_name":"sphere culture","score":0.43799999356269836},{"id":"https://openalex.org/keywords/colorectal-cancer-cell-lines","display_name":"colorectal cancer cell lines","score":0.8539999723434448},{"id":"https://openalex.org/keywords/5-fluorouracil","display_name":"5-fluorouracil","score":0.8889999985694885},{"id":"https://openalex.org/keywords/gene-expression-signatures","display_name":"gene expression signatures","score":0.7839999794960022},{"id":"https://openalex.org/keywords/disease-recurrence-prediction","display_name":"disease recurrence prediction","score":0.8429999947547913},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.8399999737739563},{"id":"https://openalex.org/keywords/tumorigenicity","display_name":"tumorigenicity","score":0.8130000233650208},{"id":"https://openalex.org/keywords/stem-cell-markers","display_name":"stem cell markers","score":0.6449999809265137}],"concepts":[{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5810161828994751},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.4942772388458252},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47873684763908386},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46457207202911377},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4612630009651184},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.41795849800109863},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33118122816085815},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3244801461696625},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.25829219818115234},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1112300455570221}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005472","descriptor_name":"Fluorouracil","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00018-012-1160-9","doi":"https://doi.org/10.1007/s00018-012-1160-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00018-012-1160-9","pdf_url":null,"source":{"id":"https://openalex.org/S60362788","display_name":"Cellular and Molecular Life Sciences","issn_l":"1420-682X","issn":["1420-682X","1420-9071"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Life Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11113113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11113113","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Mol Life Sci","raw_type":"Text"},{"id":"pmid:23007843","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23007843","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and molecular life sciences : CMLS","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11113113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11113113","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Mol Life Sci","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1483167997","https://openalex.org/W1864290935","https://openalex.org/W1965124339","https://openalex.org/W1967358345","https://openalex.org/W1995661435","https://openalex.org/W2010160578","https://openalex.org/W2011442347","https://openalex.org/W2029231546","https://openalex.org/W2032440908","https://openalex.org/W2041897873","https://openalex.org/W2045991053","https://openalex.org/W2048028355","https://openalex.org/W2051055358","https://openalex.org/W2053850923","https://openalex.org/W2056628299","https://openalex.org/W2060551076","https://openalex.org/W2062069198","https://openalex.org/W2079356804","https://openalex.org/W2080157242","https://openalex.org/W2080308138","https://openalex.org/W2081098333","https://openalex.org/W2086268110","https://openalex.org/W2089467606","https://openalex.org/W2102085111","https://openalex.org/W2105726811","https://openalex.org/W2105829583","https://openalex.org/W2109972881","https://openalex.org/W2118758371","https://openalex.org/W2127107445","https://openalex.org/W2129644533","https://openalex.org/W2136811756","https://openalex.org/W2142736326","https://openalex.org/W2146303969","https://openalex.org/W2148388780","https://openalex.org/W2150289099","https://openalex.org/W2156381851","https://openalex.org/W2157910818","https://openalex.org/W2158501712","https://openalex.org/W2164212079","https://openalex.org/W2166206246","https://openalex.org/W2166982925","https://openalex.org/W2169302611","https://openalex.org/W2178278509"],"related_works":["https://openalex.org/W2620260752","https://openalex.org/W2396166869","https://openalex.org/W2011544190","https://openalex.org/W2369821832","https://openalex.org/W3119363889","https://openalex.org/W2391817458","https://openalex.org/W2741264314","https://openalex.org/W2165354678","https://openalex.org/W2985151617","https://openalex.org/W2996834910"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}