{"id":"https://openalex.org/W2000587115","doi":"https://doi.org/10.1016/j.mrgentox.2012.04.001","title":"Apigenin ameliorates gamma radiation-induced cytogenetic alterations in cultured human blood lymphocytes","display_name":"Apigenin ameliorates gamma radiation-induced cytogenetic alterations in cultured human blood lymphocytes","publication_year":2012,"publication_date":"2012-04-09","ids":{"openalex":"https://openalex.org/W2000587115","doi":"https://doi.org/10.1016/j.mrgentox.2012.04.001","mag":"2000587115","pmid":"https://pubmed.ncbi.nlm.nih.gov/22516036"},"language":"en","primary_location":{"id":"doi:10.1016/j.mrgentox.2012.04.001","doi":"https://doi.org/10.1016/j.mrgentox.2012.04.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrgentox.2012.04.001","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000587115"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088689944","display_name":"Naziya Begum","orcid":"https://orcid.org/0000-0002-0687-5399","observed_orcids":["https://orcid.org/0000-0002-0687-5399"]},"institutions":[{"id":"https://openalex.org/I197081775","display_name":"Annamalai University","ror":"https://ror.org/01x24z140","country_code":"IN","type":"education","lineage":["https://openalex.org/I197081775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Naziya Begum","raw_affiliation_strings":["Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India","Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India","institution_ids":["https://openalex.org/I197081775"]},{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India","institution_ids":["https://openalex.org/I197081775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007462045","display_name":"Nagarajan Rajendra Prasad","orcid":"https://orcid.org/0000-0002-3937-8735","observed_orcids":["https://orcid.org/0000-0002-3937-8735"]},"institutions":[{"id":"https://openalex.org/I197081775","display_name":"Annamalai University","ror":"https://ror.org/01x24z140","country_code":"IN","type":"education","lineage":["https://openalex.org/I197081775"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"N. Rajendra Prasad","raw_affiliation_strings":["Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India. Electronic address: drprasadnr@gmail.com","Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India. Electronic address: drprasadnr@gmail.com","institution_ids":["https://openalex.org/I197081775"]},{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India","institution_ids":["https://openalex.org/I197081775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058758749","display_name":"Govindasamy Kanimozhi","orcid":"https://orcid.org/0000-0003-2873-9758","observed_orcids":["https://orcid.org/0000-0003-2873-9758"]},"institutions":[{"id":"https://openalex.org/I197081775","display_name":"Annamalai University","ror":"https://ror.org/01x24z140","country_code":"IN","type":"education","lineage":["https://openalex.org/I197081775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"G. Kanimozhi","raw_affiliation_strings":["Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India","Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002 Tamilnadu, India","institution_ids":["https://openalex.org/I197081775"]},{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 608 002, Tamilnadu, India","institution_ids":["https://openalex.org/I197081775"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004094372","display_name":"Annie Q. Hasan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127887","display_name":"Kamineni Hospitals","ror":"https://ror.org/02r0vmn14","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210127887"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Annie Q. Hasan","raw_affiliation_strings":["Dept. of Genetics and Molecular Medicine, Kamineni Hospitals, Hyderabad 500 068, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Genetics and Molecular Medicine, Kamineni Hospitals, Hyderabad 500 068, Andhra Pradesh, India","institution_ids":["https://openalex.org/I4210127887"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5007462045"],"corresponding_institution_ids":["https://openalex.org/I197081775"],"apc_list":{"value":3350,"currency":"USD","value_usd":3350},"apc_paid":null,"fwci":1.8906,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.83047663,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"747","issue":"1","first_page":"71","last_page":"76"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apigenin","display_name":"apigenin","score":1.0},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.6919999718666077},{"id":"https://openalex.org/keywords/radiation-protection","display_name":"radiation protection","score":0.6800000071525574},{"id":"https://openalex.org/keywords/gamma-radiation","display_name":"gamma radiation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/cobalt-60","display_name":"cobalt-60","score":0.8700000047683716},{"id":"https://openalex.org/keywords/chromosomal-damage","display_name":"chromosomal damage","score":0.7990000247955322},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8159999847412109},{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.8939999938011169},{"id":"https://openalex.org/keywords/dicentric-chromosomes","display_name":"dicentric chromosomes","score":0.8659999966621399},{"id":"https://openalex.org/keywords/acentric-fragments","display_name":"acentric fragments","score":0.8450000286102295},{"id":"https://openalex.org/keywords/nucleoplasmic-bridges","display_name":"nucleoplasmic bridges","score":0.9670000076293945},{"id":"https://openalex.org/keywords/nuclear-buds","display_name":"nuclear buds","score":0.6110000014305115},{"id":"https://openalex.org/keywords/human-peripheral-blood-lymphocytes","display_name":"human peripheral blood lymphocytes","score":0.824999988079071},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C2778609962","wikidata":"https://www.wikidata.org/wiki/Q424567","display_name":"Apigenin","level":4,"score":0.7568045854568481},{"id":"https://openalex.org/C103037022","wikidata":"https://www.wikidata.org/wiki/Q5272374","display_name":"Dicentric chromosome","level":5,"score":0.5470276474952698},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5312628149986267},{"id":"https://openalex.org/C2780639530","wikidata":"https://www.wikidata.org/wiki/Q275459","display_name":"Radiation sickness","level":2,"score":0.525611162185669},{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.5167752504348755},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.35420966148376465},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23885762691497803},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19550198316574097},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19412824511528015},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1771777868270874},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.14708960056304932},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.1283772885799408},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07739242911338806},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.06613144278526306},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.0},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005720","descriptor_name":"Gamma Rays","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D011829","descriptor_name":"Radiation Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011837","descriptor_name":"Radiation-Protective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D016587","descriptor_name":"Antimutagenic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D047310","descriptor_name":"Apigenin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mrgentox.2012.04.001","doi":"https://doi.org/10.1016/j.mrgentox.2012.04.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrgentox.2012.04.001","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},{"id":"pmid:22516036","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22516036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320720","display_name":"Indian Council of Medical Research","ror":"https://ror.org/0492wrx28"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W13193923","https://openalex.org/W1520315220","https://openalex.org/W1970557926","https://openalex.org/W1976997619","https://openalex.org/W1981671382","https://openalex.org/W1989156168","https://openalex.org/W1992418109","https://openalex.org/W2001115051","https://openalex.org/W2004702074","https://openalex.org/W2011953196","https://openalex.org/W2013588043","https://openalex.org/W2013611824","https://openalex.org/W2014491004","https://openalex.org/W2020267283","https://openalex.org/W2021333182","https://openalex.org/W2022929617","https://openalex.org/W2029967801","https://openalex.org/W2032080607","https://openalex.org/W2032710545","https://openalex.org/W2033210584","https://openalex.org/W2034485370","https://openalex.org/W2037336622","https://openalex.org/W2047074549","https://openalex.org/W2051990809","https://openalex.org/W2057357901","https://openalex.org/W2061728264","https://openalex.org/W2062375412","https://openalex.org/W2067291561","https://openalex.org/W2068198382","https://openalex.org/W2069975987","https://openalex.org/W2071590728","https://openalex.org/W2074169536","https://openalex.org/W2074951329","https://openalex.org/W2080568589","https://openalex.org/W2081201480","https://openalex.org/W2085287557","https://openalex.org/W2085446652","https://openalex.org/W2085695808","https://openalex.org/W2086185059","https://openalex.org/W2092629964","https://openalex.org/W2098883242","https://openalex.org/W2104000223","https://openalex.org/W2104731141","https://openalex.org/W2112784018","https://openalex.org/W2114918609","https://openalex.org/W2116571079","https://openalex.org/W2120762408","https://openalex.org/W2129899300","https://openalex.org/W2130554457","https://openalex.org/W2133323814","https://openalex.org/W2134281960","https://openalex.org/W2137094112","https://openalex.org/W2138322020","https://openalex.org/W2142519394","https://openalex.org/W2148418766","https://openalex.org/W2162319796","https://openalex.org/W2186942424","https://openalex.org/W2204293707","https://openalex.org/W2274913842","https://openalex.org/W2318209979","https://openalex.org/W2992175571","https://openalex.org/W4321258548","https://openalex.org/W6667524973"],"related_works":["https://openalex.org/W2029967801","https://openalex.org/W1982338880","https://openalex.org/W2147626826","https://openalex.org/W3134943992","https://openalex.org/W4285403008","https://openalex.org/W1998916196","https://openalex.org/W2002483248","https://openalex.org/W1984421269","https://openalex.org/W4401556257","https://openalex.org/W2019648453"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}