{"id":"https://openalex.org/W2000580789","doi":"https://doi.org/10.1039/c1cc11062d","title":"Mixed DNA-functionalized nanoparticle probes for surface-enhanced Raman scattering-based multiplex DNA detection","display_name":"Mixed DNA-functionalized nanoparticle probes for surface-enhanced Raman scattering-based multiplex DNA detection","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2000580789","doi":"https://doi.org/10.1039/c1cc11062d","mag":"2000580789","pmid":"https://pubmed.ncbi.nlm.nih.gov/21594282"},"language":"en","primary_location":{"id":"doi:10.1039/c1cc11062d","doi":"https://doi.org/10.1039/c1cc11062d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c1cc11062d","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100604717","display_name":"Zhiliang Zhang","orcid":"https://orcid.org/0000-0003-0569-848X","observed_orcids":["https://orcid.org/0000-0003-0569-848X"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]},{"id":"https://openalex.org/I4405282488","display_name":"Shandong Polytechnic","ror":"https://ror.org/05xc6df26","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210096525","https://openalex.org/I4387155179","https://openalex.org/I4405282488"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiliang Zhang","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","Research Center of Analysis and Test, Shandong Polytechnic University, Jinan 250353, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]},{"raw_affiliation_string":"Research Center of Analysis and Test, Shandong Polytechnic University, Jinan 250353, China","institution_ids":["https://openalex.org/I4405282488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101973184","display_name":"Yongqiang Wen","orcid":"https://orcid.org/0000-0002-1924-4166","observed_orcids":["https://orcid.org/0000-0002-1924-4166"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yongqiang Wen","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057905432","display_name":"Ying Ma","orcid":"https://orcid.org/0000-0002-5649-7410","observed_orcids":["https://orcid.org/0000-0002-5649-7410","https://orcid.org/0000-0002-0515-6501"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Ma","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101801039","display_name":"Jia Liang Luo","orcid":"https://orcid.org/0000-0002-9245-5680","observed_orcids":["https://orcid.org/0000-0002-9245-5680"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Luo","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089379689","display_name":"Lei Jiang","orcid":"https://orcid.org/0000-0003-4579-728X","observed_orcids":["https://orcid.org/0000-0003-4579-728X","https://orcid.org/0000-0002-4084-1125","https://orcid.org/0000-0002-8996-4767"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Jiang","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109553608","display_name":"Yanlin Song","orcid":"https://orcid.org/0000-0002-0267-3917","observed_orcids":["https://orcid.org/0000-0002-0267-3917"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210116048","display_name":"Beijing National Laboratory for Molecular Sciences","ror":"https://ror.org/02601yx74","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210116048"]},{"id":"https://openalex.org/I4210155088","display_name":"Institute of Chemistry","ror":"https://ror.org/048y1rc66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210155088"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanlin Song","raw_affiliation_strings":["Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101973184","https://openalex.org/A5109553608"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210116048","https://openalex.org/I4210155088"],"apc_list":null,"apc_paid":null,"fwci":4.986,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.96281556,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"47","issue":"26","first_page":"7407","last_page":"7407"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silver-nanoparticles","display_name":"silver nanoparticles","score":0.9509999752044678},{"id":"https://openalex.org/keywords/dna-functionalized-nanoparticles","display_name":"DNA-functionalized nanoparticles","score":0.722000002861023},{"id":"https://openalex.org/keywords/surface-enhanced-raman-scattering","display_name":"surface-enhanced Raman scattering","score":0.8989999890327454},{"id":"https://openalex.org/keywords/multiplex-dna-detection","display_name":"multiplex DNA detection","score":0.968999981880188},{"id":"https://openalex.org/keywords/dna-probes","display_name":"DNA probes","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.7806182503700256},{"id":"https://openalex.org/C169573571","wikidata":"https://www.wikidata.org/wiki/Q466824","display_name":"Raman scattering","level":3,"score":0.7031481266021729},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6552024483680725},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.6523184180259705},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5531724691390991},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5395711064338684},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.4657951593399048},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.4509338140487671},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30285924673080444},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.11700078845024109},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.082375168800354},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0803525447845459},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0748986303806305},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.07022526860237122},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06377413868904114}],"mesh":[{"descriptor_ui":"D004220","descriptor_name":"Disulfides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009838","descriptor_name":"Oligodeoxyribonucleotides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012834","descriptor_name":"Silver","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/c1cc11062d","doi":"https://doi.org/10.1039/c1cc11062d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c1cc11062d","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},{"id":"pmid:21594282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21594282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical communications (Cambridge, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1967470447","https://openalex.org/W1968156574","https://openalex.org/W1987749458","https://openalex.org/W1994150421","https://openalex.org/W1998831948","https://openalex.org/W2005112256","https://openalex.org/W2016042453","https://openalex.org/W2030583923","https://openalex.org/W2035815452","https://openalex.org/W2046516901","https://openalex.org/W2064736230","https://openalex.org/W2076090861","https://openalex.org/W2079954478","https://openalex.org/W2084205985","https://openalex.org/W2087685496","https://openalex.org/W2091588319","https://openalex.org/W2097000290","https://openalex.org/W2151671693","https://openalex.org/W2163072035"],"related_works":["https://openalex.org/W1988698256","https://openalex.org/W2091809415","https://openalex.org/W2801677525","https://openalex.org/W2160870426","https://openalex.org/W1802215081","https://openalex.org/W2148962347","https://openalex.org/W7052208192","https://openalex.org/W1977333614","https://openalex.org/W2014487114","https://openalex.org/W6996950715"],"abstract_inverted_index":{"Highly":[0],"stable":[1],"silver":[2,12],"nanoparticle-oligonucleotide":[3],"conjugates":[4],"were":[5,18],"prepared.":[6],"Based":[7],"on":[8],"the":[9],"mixed":[10],"DNA-functionalized":[11],"nanoparticles":[13],"(AgNPs),":[14],"multiplex":[15],"DNA":[16],"detections":[17],"demonstrated":[19],"successfully":[20],"by":[21],"SERS.":[22]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}