{"id":"https://openalex.org/W2000568918","doi":"https://doi.org/10.1016/j.jconrel.2013.03.036","title":"Thermosensitive liposomes for localized delivery and triggered release of chemotherapy","display_name":"Thermosensitive liposomes for localized delivery and triggered release of chemotherapy","publication_year":2013,"publication_date":"2013-04-16","ids":{"openalex":"https://openalex.org/W2000568918","doi":"https://doi.org/10.1016/j.jconrel.2013.03.036","mag":"2000568918","pmid":"https://pubmed.ncbi.nlm.nih.gov/23583706","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5127786"},"language":"en","primary_location":{"id":"doi:10.1016/j.jconrel.2013.03.036","doi":"https://doi.org/10.1016/j.jconrel.2013.03.036","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jconrel.2013.03.036","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000568918"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5127786","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077936705","display_name":"Terence Ta","orcid":"https://orcid.org/0000-0002-8382-8860","observed_orcids":["https://orcid.org/0000-0002-8382-8860"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Terence Ta","raw_affiliation_strings":["Department of Biomedical Engineering, Boston University, 44 Cummington St., Room 403, Boston, USA. terence.ta@gmail.com","Department of Biomedical Engineering, Boston University, 44 Cummington St., Room 403, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Boston University, 44 Cummington St., Room 403, Boston, USA. terence.ta@gmail.com","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Boston University, 44 Cummington St., Room 403, Boston, USA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072450920","display_name":"Tyrone M. Porter","orcid":"https://orcid.org/0000-0002-7239-4091","observed_orcids":["https://orcid.org/0000-0002-7239-4091"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyrone M. Porter","raw_affiliation_strings":["Department of Mechanical Engineering, Boston University, 110 Cummington St., Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Boston University, 110 Cummington St., Boston, USA","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5077936705"],"corresponding_institution_ids":["https://openalex.org/I111088046"],"apc_list":{"value":4440,"currency":"USD","value_usd":4440},"apc_paid":null,"fwci":2.0749,"has_fulltext":false,"cited_by_count":422,"citation_normalized_percentile":{"value":0.88709677,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"169","issue":"1-2","first_page":"112","last_page":"125"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.016599999740719795,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thermosensitive-liposomes","display_name":"thermosensitive liposomes","score":0.996999979019165},{"id":"https://openalex.org/keywords/stimuli-responsive-liposomes","display_name":"stimuli-responsive liposomes","score":0.9589999914169312},{"id":"https://openalex.org/keywords/triggered-drug-release","display_name":"triggered drug release","score":0.9390000104904175},{"id":"https://openalex.org/keywords/gel-to-liquid-crystalline-phase-transition","display_name":"gel to liquid-crystalline phase transition","score":0.8629999756813049},{"id":"https://openalex.org/keywords/lysolipids","display_name":"lysolipids","score":0.9269999861717224},{"id":"https://openalex.org/keywords/thermoresponsive-polymers","display_name":"thermoresponsive polymers","score":0.9610000252723694},{"id":"https://openalex.org/keywords/hyperthermia","display_name":"hyperthermia","score":0.7419999837875366},{"id":"https://openalex.org/keywords/tumor-heating","display_name":"tumor heating","score":0.7369999885559082},{"id":"https://openalex.org/keywords/local-drug-delivery","display_name":"local drug delivery","score":0.656000018119812},{"id":"https://openalex.org/keywords/controlled-release","display_name":"controlled release","score":0.41499999165534973}],"concepts":[{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.9461820125579834},{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.6210578083992004},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5764790773391724},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.514800488948822},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3610670566558838},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3506743311882019},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34892284870147705},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3345554769039154},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33393222093582153},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2493487000465393},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.23200276494026184},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.14351540803909302},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11436432600021362}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jconrel.2013.03.036","doi":"https://doi.org/10.1016/j.jconrel.2013.03.036","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jconrel.2013.03.036","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"},{"id":"pmid:23583706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23583706","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of controlled release : official journal of the Controlled Release Society","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4086134","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5127786","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5127786","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5127786/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Control Release","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4086134","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5127786","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3006722093","display_name":"MRI-guided HIFU-mediated heating and lesion formation enhanced with phase-shift n","funder_award_id":"R21EB009493","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G7146388761","display_name":"Training in Biomolecular Pharmacology","funder_award_id":"T32GM008541","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":150,"referenced_works":["https://openalex.org/W37146181","https://openalex.org/W49581708","https://openalex.org/W96051963","https://openalex.org/W127567241","https://openalex.org/W175938947","https://openalex.org/W236637588","https://openalex.org/W309048867","https://openalex.org/W348674655","https://openalex.org/W393153318","https://openalex.org/W409362985","https://openalex.org/W1486075838","https://openalex.org/W1527666256","https://openalex.org/W1539330970","https://openalex.org/W1607235602","https://openalex.org/W1664302441","https://openalex.org/W1868696300","https://openalex.org/W1871308790","https://openalex.org/W1899397722","https://openalex.org/W1946720377","https://openalex.org/W1964482344","https://openalex.org/W1965097716","https://openalex.org/W1965300836","https://openalex.org/W1968337555","https://openalex.org/W1970239046","https://openalex.org/W1970954627","https://openalex.org/W1974187781","https://openalex.org/W1977132718","https://openalex.org/W1978139448","https://openalex.org/W1978521258","https://openalex.org/W1978584972","https://openalex.org/W1982194007","https://openalex.org/W1982432835","https://openalex.org/W1983387455","https://openalex.org/W1984556018","https://openalex.org/W1984658112","https://openalex.org/W1984928076","https://openalex.org/W1985859113","https://openalex.org/W1986949893","https://openalex.org/W1988607076","https://openalex.org/W1988878486","https://openalex.org/W1989254508","https://openalex.org/W1989483336","https://openalex.org/W1989575919","https://openalex.org/W1990163407","https://openalex.org/W1990565395","https://openalex.org/W1996158048","https://openalex.org/W1998346656","https://openalex.org/W1998575668","https://openalex.org/W1998886157","https://openalex.org/W2000144812","https://openalex.org/W2001143840","https://openalex.org/W2002516695","https://openalex.org/W2006447267","https://openalex.org/W2007844880","https://openalex.org/W2009306453","https://openalex.org/W2011835180","https://openalex.org/W2012468775","https://openalex.org/W2012861715","https://openalex.org/W2013086386","https://openalex.org/W2015626183","https://openalex.org/W2016414221","https://openalex.org/W2022832994","https://openalex.org/W2023876494","https://openalex.org/W2027552348","https://openalex.org/W2028211453","https://openalex.org/W2032760352","https://openalex.org/W2033294149","https://openalex.org/W2034269086","https://openalex.org/W2036335933","https://openalex.org/W2037048276","https://openalex.org/W2038225831","https://openalex.org/W2038474294","https://openalex.org/W2039864709","https://openalex.org/W2039929826","https://openalex.org/W2040150720","https://openalex.org/W2044556787","https://openalex.org/W2045713969","https://openalex.org/W2045763862","https://openalex.org/W2047421804","https://openalex.org/W2048758535","https://openalex.org/W2050715080","https://openalex.org/W2052571302","https://openalex.org/W2055904567","https://openalex.org/W2058578539","https://openalex.org/W2059202415","https://openalex.org/W2061939879","https://openalex.org/W2062952604","https://openalex.org/W2063044288","https://openalex.org/W2065245211","https://openalex.org/W2065510602","https://openalex.org/W2069331972","https://openalex.org/W2070825008","https://openalex.org/W2071921998","https://openalex.org/W2072459212","https://openalex.org/W2073038820","https://openalex.org/W2074049977","https://openalex.org/W2075266623","https://openalex.org/W2077474285","https://openalex.org/W2078516817","https://openalex.org/W2078909289","https://openalex.org/W2079722587","https://openalex.org/W2082511916","https://openalex.org/W2084559690","https://openalex.org/W2088257510","https://openalex.org/W2089155556","https://openalex.org/W2098448810","https://openalex.org/W2101673712","https://openalex.org/W2102437295","https://openalex.org/W2106016270","https://openalex.org/W2108165319","https://openalex.org/W2111220039","https://openalex.org/W2111605241","https://openalex.org/W2117589663","https://openalex.org/W2119964155","https://openalex.org/W2128512834","https://openalex.org/W2130472147","https://openalex.org/W2141519886","https://openalex.org/W2141713397","https://openalex.org/W2143257840","https://openalex.org/W2144346703","https://openalex.org/W2146275007","https://openalex.org/W2146707181","https://openalex.org/W2146757262","https://openalex.org/W2150932917","https://openalex.org/W2152273715","https://openalex.org/W2153856059","https://openalex.org/W2156124327","https://openalex.org/W2161580101","https://openalex.org/W2161915613","https://openalex.org/W2162269896","https://openalex.org/W2164912911","https://openalex.org/W2166699632","https://openalex.org/W2169592168","https://openalex.org/W2171548026","https://openalex.org/W2171946597","https://openalex.org/W2174465527","https://openalex.org/W2185469212","https://openalex.org/W2209147002","https://openalex.org/W2263448484","https://openalex.org/W2316021289","https://openalex.org/W2322643780","https://openalex.org/W2417601007","https://openalex.org/W2469323193","https://openalex.org/W2500145168","https://openalex.org/W3152092299","https://openalex.org/W4239673627","https://openalex.org/W4245635197","https://openalex.org/W6684559784","https://openalex.org/W6720330260","https://openalex.org/W6979024174"],"related_works":["https://openalex.org/W4320010287","https://openalex.org/W2024720092","https://openalex.org/W1974187781","https://openalex.org/W4415729022","https://openalex.org/W2079722587","https://openalex.org/W4285395329","https://openalex.org/W2004426884","https://openalex.org/W1622668565","https://openalex.org/W4292730716"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":30},{"year":2025,"cited_by_count":34},{"year":2024,"cited_by_count":32},{"year":2023,"cited_by_count":32},{"year":2022,"cited_by_count":45},{"year":2021,"cited_by_count":32},{"year":2020,"cited_by_count":30},{"year":2019,"cited_by_count":28},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":33},{"year":2016,"cited_by_count":32},{"year":2015,"cited_by_count":35},{"year":2014,"cited_by_count":24},{"year":2013,"cited_by_count":7}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}