{"id":"https://openalex.org/W2000511735","doi":"https://doi.org/10.1107/s0907444999000244","title":"Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase","display_name":"Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase","publication_year":1999,"publication_date":"1999-04-01","ids":{"openalex":"https://openalex.org/W2000511735","doi":"https://doi.org/10.1107/s0907444999000244","mag":"2000511735","pmid":"https://pubmed.ncbi.nlm.nih.gov/10089308"},"language":"en","primary_location":{"id":"doi:10.1107/s0907444999000244","doi":"https://doi.org/10.1107/s0907444999000244","is_oa":false,"landing_page_url":"https://doi.org/10.1107/s0907444999000244","pdf_url":null,"source":{"id":"https://openalex.org/S114502960","display_name":"Acta Crystallographica Section D Biological Crystallography","issn_l":"0907-4449","issn":["0907-4449","1399-0047"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section D Biological Crystallography","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073349983","display_name":"Debashis Ghosh","orcid":"https://orcid.org/0000-0001-8810-6392","observed_orcids":["https://orcid.org/0000-0001-8810-6392"]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]},{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Debashis Ghosh","raw_affiliation_strings":["Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA. ghosh@hwi.buffalo.edu","Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","Roswell Park Cancer Institute, Buffalo, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA. ghosh@hwi.buffalo.edu","institution_ids":["https://openalex.org/I1287610024"]},{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I1287610024"]},{"raw_affiliation_string":"Roswell Park Cancer Institute, Buffalo, New York, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111546615","display_name":"Mary Erman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Erman","raw_affiliation_strings":["Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008714730","display_name":"Mark W. Sawicki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Sawicki","raw_affiliation_strings":["Roswell Park Cancer Institute, Buffalo, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Cancer Institute, Buffalo, New York, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084547472","display_name":"Puloma Lala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Puloma Lala","raw_affiliation_strings":["Roswell Park Cancer Institute, Buffalo, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roswell Park Cancer Institute, Buffalo, New York, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042414927","display_name":"D. R. Weeks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel R. Weeks","raw_affiliation_strings":["Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077752734","display_name":"Naiyin Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naiyin Li","raw_affiliation_strings":["Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111586494","display_name":"Walter A. Pangborn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter Pangborn","raw_affiliation_strings":["Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman-Woodward Medical Research Institute, 73 High Street, Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043283639","display_name":"Daniel J. Thiel","orcid":"https://orcid.org/0000-0003-1398-3512","observed_orcids":["https://orcid.org/0000-0003-1398-3512"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153242","display_name":"Cornell High Energy Synchrotron Source","ror":"https://ror.org/032bgnz47","country_code":"US","type":"education","lineage":["https://openalex.org/I4387153242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel J. Thiel","raw_affiliation_strings":["Cornell High Energy Synchrotron Source, Ithaca, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell High Energy Synchrotron Source, Ithaca, New York, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113570579","display_name":"Hans J\u00f6rnvall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hans J\u00f6rnvall","raw_affiliation_strings":["Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039905637","display_name":"Rodrigo A. Guti\u00e9rrez","orcid":"https://orcid.org/0000-0002-5961-5005","observed_orcids":["https://orcid.org/0000-0002-5961-5005"]},"institutions":[{"id":"https://openalex.org/I162148367","display_name":"Pontificia Universidad Cat\u00f3lica de Chile","ror":"https://ror.org/04teye511","country_code":"CL","type":"education","lineage":["https://openalex.org/I162148367"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Rodrigo Gutierrez","raw_affiliation_strings":["Pontificia Universidad Catolica de Chile, Santiago, Chile","Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pontificia Universidad Catolica de Chile, Santiago, Chile","institution_ids":["https://openalex.org/I162148367"]},{"raw_affiliation_string":"Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile","institution_ids":["https://openalex.org/I162148367"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028396037","display_name":"Jaime P. Eyzaguirre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162148367","display_name":"Pontificia Universidad Cat\u00f3lica de Chile","ror":"https://ror.org/04teye511","country_code":"CL","type":"education","lineage":["https://openalex.org/I162148367"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Jaime Eyzaguirre","raw_affiliation_strings":["Pontificia Universidad Catolica de Chile, Santiago, Chile","Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pontificia Universidad Catolica de Chile, Santiago, Chile","institution_ids":["https://openalex.org/I162148367"]},{"raw_affiliation_string":"Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile","institution_ids":["https://openalex.org/I162148367"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4740,"currency":"USD","value_usd":4740},"apc_paid":null,"fwci":1.1763,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.75546913,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"55","issue":"4","first_page":"779","last_page":"784"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acetyl-xylan-esterase","display_name":"acetyl xylan esterase","score":0.878000020980835},{"id":"https://openalex.org/keywords/penicillium-purpurogenum","display_name":"Penicillium purpurogenum","score":0.9739999771118164},{"id":"https://openalex.org/keywords/iodination","display_name":"iodination","score":0.7730000019073486},{"id":"https://openalex.org/keywords/iodotyrosines","display_name":"iodotyrosines","score":0.8479999899864197},{"id":"https://openalex.org/keywords/tyrosine","display_name":"tyrosine","score":0.6700000166893005},{"id":"https://openalex.org/keywords/protein-structure-determination","display_name":"protein structure determination","score":0.6349999904632568},{"id":"https://openalex.org/keywords/resonant-scattering","display_name":"resonant scattering","score":0.8059999942779541},{"id":"https://openalex.org/keywords/alpha-beta-hydrolase","display_name":"alpha/beta hydrolase","score":0.8669999837875366},{"id":"https://openalex.org/keywords/xylan-degradation","display_name":"xylan degradation","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7730462551116943},{"id":"https://openalex.org/C65973085","wikidata":"https://www.wikidata.org/wiki/Q888529","display_name":"Halogenation","level":2,"score":0.5739034414291382},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.5598914623260498},{"id":"https://openalex.org/C115624301","wikidata":"https://www.wikidata.org/wiki/Q895901","display_name":"Crystal structure","level":2,"score":0.5172160863876343},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.5012338161468506},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4913746416568756},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.4878532886505127},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4642055630683899},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4552049934864044},{"id":"https://openalex.org/C112247285","wikidata":"https://www.wikidata.org/wiki/Q6934948","display_name":"Multiple isomorphous replacement","level":4,"score":0.44015762209892273},{"id":"https://openalex.org/C2777261171","wikidata":"https://www.wikidata.org/wiki/Q418750","display_name":"Esterase","level":3,"score":0.440014511346817},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4385388493537903},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.26816099882125854},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.19331535696983337},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0940408706665039},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000115","descriptor_name":"Acetylesterase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000115","descriptor_name":"Acetylesterase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D007470","descriptor_name":"Monoiodotyrosine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010407","descriptor_name":"Penicillium","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1107/s0907444999000244","doi":"https://doi.org/10.1107/s0907444999000244","is_oa":false,"landing_page_url":"https://doi.org/10.1107/s0907444999000244","pdf_url":null,"source":{"id":"https://openalex.org/S114502960","display_name":"Acta Crystallographica Section D Biological Crystallography","issn_l":"0907-4449","issn":["0907-4449","1399-0047"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section D Biological Crystallography","raw_type":"journal-article"},{"id":"pmid:10089308","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10089308","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta crystallographica. Section D, Biological crystallography","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W313184597","https://openalex.org/W1601974339","https://openalex.org/W1988382654","https://openalex.org/W1994034310","https://openalex.org/W2015335500","https://openalex.org/W2028094900","https://openalex.org/W2040430564","https://openalex.org/W2049521571","https://openalex.org/W2052492429","https://openalex.org/W2063142947","https://openalex.org/W2070429807","https://openalex.org/W2075574354","https://openalex.org/W2080528351","https://openalex.org/W2091002962","https://openalex.org/W2142479284","https://openalex.org/W2154061135"],"related_works":["https://openalex.org/W2330862058","https://openalex.org/W1966730412","https://openalex.org/W2017697736","https://openalex.org/W1931804440","https://openalex.org/W1975984025","https://openalex.org/W2084131741","https://openalex.org/W2016409521","https://openalex.org/W2152076749","https://openalex.org/W2023201102","https://openalex.org/W2063996622"],"abstract_inverted_index":{"Enzymatic":[0],"and":[1,31,73,92,131,158],"non-enzymatic":[2,38],"iodination":[3,15,103],"of":[4,34,40,46,68,79,84,113,120,141,152,168],"the":[5,29,85,114,121,139,142,150,165],"amino":[6],"acid":[7],"tyrosine":[8,44],"is":[9],"a":[10,47,76],"well":[11],"known":[12],"phenomenon.":[13],"The":[14,82,102,118],"technique":[16,104],"has":[17,62,105],"been":[18,106],"widely":[19],"used":[20],"for":[21],"labeling":[22],"proteins.":[23],"Using":[24],"high-resolution":[25],"X-ray":[26],"crystallographic":[27],"techniques,":[28],"chemical":[30],"three-dimensional":[32],"structures":[33],"iodotyrosines":[35],"formed":[36],"by":[37,129],"incorporation":[39],"I":[41,135,156],"atoms":[42,157,160],"into":[43],"residues":[45,70],"crystalline":[48],"protein":[49],"are":[50,87],"described.":[51],"Acetylxylan":[52],"esterase":[53],"(AXE":[54],"II;":[55],"207":[56],"amino-acid":[57],"residues)":[58],"from":[59,134],"Penicillium":[60],"purpurogenum":[61],"substrate":[63],"specificities":[64],"towards":[65],"acetate":[66],"esters":[67],"D-xylopyranose":[69],"in":[71],"xylan":[72],"belongs":[74],"to":[75,94,108,164],"new":[77],"class":[78],"alpha/beta":[80],"hydrolases.":[81],"crystals":[83],"enzyme":[86,122],"highly":[88],"ordered,":[89],"tightly":[90],"packed":[91],"diffract":[93],"better":[95],"than":[96],"sub-angstr\u00f6m":[97],"resolution":[98,127],"at":[99,124,145,161],"85":[100],"K.":[101],"utilized":[107],"prepare":[109],"an":[110],"isomorphous":[111],"derivative":[112],"AXE":[115],"II":[116],"crystal.":[117],"structure":[119,140],"determined":[123],"1.10":[125],"A":[126,147],"exclusively":[128],"normal":[130],"anomalous":[132],"scattering":[133],"atoms,":[136],"along":[137],"with":[138],"iodinated":[143],"complex":[144],"1.80":[146],"resolution,":[148],"demonstrate":[149],"formation":[151],"covalent":[153],"bonds":[154],"between":[155],"C":[159],"ortho":[162],"positions":[163],"hydroxyl":[166],"groups":[167],"two":[169],"tyrosyl":[170],"moieties,":[171],"yielding":[172],"iodotyrosines.":[173]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}