{"id":"https://openalex.org/W2000500806","doi":"https://doi.org/10.1002/jcp.20394","title":"Effects of soluble laminin on organelle transport and neurite growth in cultured mouse dorsal root ganglion neurons: Difference between primary neurites and branches","display_name":"Effects of soluble laminin on organelle transport and neurite growth in cultured mouse dorsal root ganglion neurons: Difference between primary neurites and branches","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2000500806","doi":"https://doi.org/10.1002/jcp.20394","mag":"2000500806","pmid":"https://pubmed.ncbi.nlm.nih.gov/15887233"},"language":"en","primary_location":{"id":"doi:10.1002/jcp.20394","doi":"https://doi.org/10.1002/jcp.20394","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcp.20394","pdf_url":null,"source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113735629","display_name":"Ken\u2010ichi Kohno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ken-Ichi Kohno","raw_affiliation_strings":["Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan","institution_ids":["https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109248098","display_name":"Tadashi Kawakami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadashi Kawakami","raw_affiliation_strings":["Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan","institution_ids":["https://openalex.org/I64189623"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067132830","display_name":"Hiromi Hiruma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiromi Hiruma","raw_affiliation_strings":["Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan","institution_ids":["https://openalex.org/I64189623"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5067132830"],"corresponding_institution_ids":["https://openalex.org/I64189623"],"apc_list":{"value":5230,"currency":"USD","value_usd":5230},"apc_paid":null,"fwci":0.4815,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.55057921,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"205","issue":"2","first_page":"253","last_page":"261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurite-outgrowth","display_name":"neurite outgrowth","score":0.8740000128746033},{"id":"https://openalex.org/keywords/organelle-transport","display_name":"organelle transport","score":0.8849999904632568},{"id":"https://openalex.org/keywords/dorsal-root-ganglion-neurons","display_name":"dorsal root ganglion neurons","score":0.9729999899864197},{"id":"https://openalex.org/keywords/neurite-branching","display_name":"neurite branching","score":0.9020000100135803},{"id":"https://openalex.org/keywords/growth-cones","display_name":"growth cones","score":0.7829999923706055},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8389999866485596},{"id":"https://openalex.org/keywords/axonal-elongation","display_name":"axon elongation","score":0.6010000109672546},{"id":"https://openalex.org/keywords/time-lapse-imaging","display_name":"time-lapse imaging","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C113246987","wikidata":"https://www.wikidata.org/wiki/Q1534415","display_name":"Neurite","level":3,"score":0.9342343211174011},{"id":"https://openalex.org/C2779814568","wikidata":"https://www.wikidata.org/wiki/Q58345","display_name":"Laminin","level":3,"score":0.8841190338134766},{"id":"https://openalex.org/C135903288","wikidata":"https://www.wikidata.org/wiki/Q559423","display_name":"Growth cone","level":3,"score":0.7908286452293396},{"id":"https://openalex.org/C2776281502","wikidata":"https://www.wikidata.org/wiki/Q1395415","display_name":"Dorsal root ganglion","level":3,"score":0.716627836227417},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6731690168380737},{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.5742735266685486},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5451499819755554},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.45584505796432495},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4510207176208496},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.3487764000892639},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3205080032348633},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.287524938583374},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1647210419178009},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.12996527552604675},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.12252235412597656}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005727","descriptor_name":"Ganglia, Spinal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007797","descriptor_name":"Laminin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015388","descriptor_name":"Organelles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015388","descriptor_name":"Organelles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016501","descriptor_name":"Neurites","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016501","descriptor_name":"Neurites","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018715","descriptor_name":"Microscopy, Video","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020439","descriptor_name":"Growth Cones","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020439","descriptor_name":"Growth Cones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jcp.20394","doi":"https://doi.org/10.1002/jcp.20394","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcp.20394","pdf_url":null,"source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},{"id":"pmid:15887233","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15887233","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cellular physiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324670","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1916984064","https://openalex.org/W1969898516","https://openalex.org/W1971033002","https://openalex.org/W1973294901","https://openalex.org/W1974547255","https://openalex.org/W1982609638","https://openalex.org/W1993783254","https://openalex.org/W1994556000","https://openalex.org/W2011110539","https://openalex.org/W2017900900","https://openalex.org/W2028997371","https://openalex.org/W2035339007","https://openalex.org/W2037863585","https://openalex.org/W2038344135","https://openalex.org/W2038850809","https://openalex.org/W2043066544","https://openalex.org/W2043710296","https://openalex.org/W2046223223","https://openalex.org/W2049269457","https://openalex.org/W2054329339","https://openalex.org/W2091994452","https://openalex.org/W2092274103","https://openalex.org/W2107438038","https://openalex.org/W2211410772"],"related_works":["https://openalex.org/W2049269457","https://openalex.org/W2015195228","https://openalex.org/W2066375551","https://openalex.org/W2011110539","https://openalex.org/W2092274103","https://openalex.org/W2094725235","https://openalex.org/W2797656047","https://openalex.org/W2024861173","https://openalex.org/W2006501418","https://openalex.org/W2211410772"],"abstract_inverted_index":{"Laminin,":[0],"an":[1],"extracellular":[2,44],"matrix":[3],"molecule,":[4],"is":[5],"known":[6],"to":[7,26,150,205,209],"promote":[8],"neurite":[9,27,130],"growth.":[10],"In":[11,117,156,165],"the":[12,15,43,49,77,82,106,129,139,173,177,181,189],"present":[13],"study,":[14],"effects":[16],"of":[17,51,79,84,98,109,115,122,138,144,180,191,199,202],"soluble":[18,58,167],"laminin":[19,59,123,151,168,187],"on":[20,48],"organelle":[21,126,170,210],"transport":[22],"and":[23,63,92,132,176,197],"their":[24],"relation":[25],"growth":[28,96,107,133,140,154,158,174],"were":[29,73,101],"investigated":[30],"in":[31,128,148,152,172],"cultured":[32],"dissociated":[33],"mouse":[34],"dorsal":[35],"root":[36],"ganglion":[37],"(DRG)":[38],"neurons.":[39,53],"Laminin":[40,104],"added":[41],"into":[42,162],"medium":[45],"was":[46],"deposited":[47],"surface":[50],"DRG":[52,54],"neurons":[55],"incubated":[56],"with":[57],"exhibited":[60],"branched,":[61],"long,":[62],"thin":[64],"neurites.":[65],"Time-lapse":[66],"study":[67],"demonstrated":[68],"that":[69,114,186],"many":[70],"small-diameter":[71],"branches":[72,93],"newly":[74],"formed":[75],"after":[76],"addition":[78,121],"laminin.":[80],"Thus,":[81],"growths":[83],"large-diameter":[85],"primary":[86,99,110,118,145,192],"neuritis,":[87,100],"arising":[88],"from":[89,95],"cell":[90],"bodies":[91],"extended":[94],"cones":[97],"analyzed":[102],"separately.":[103],"decreased":[105,125],"rate":[108],"neurites":[111,146,193],"but":[112,194],"increased":[113,169],"branches.":[116,164],"neurites,":[119],"acute":[120],"rapidly":[124],"movement":[127,171],"shaft":[131],"cone,":[134],"accompanied":[135],"by":[136],"slowing":[137],"cone":[141,175],"advance.":[142],"Branching":[143],"occurred":[147],"response":[149],"some":[153],"cones.":[155],"these":[157],"cones,":[159],"organelles":[160],"protruded":[161],"nascent":[163],"branches,":[166,200],"distal":[178],"portion":[179],"shaft.":[182],"These":[183],"results":[184],"suggest":[185],"inhibits":[188],"elongation":[190,198],"promotes":[195],"branching":[196],"all":[201],"which":[203],"seem":[204],"be":[206],"closely":[207],"related":[208],"transport.":[211]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}