{"id":"https://openalex.org/W2000491724","doi":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","title":"Immunogenic Properties of \u03b1(1 \u2192 6) Dextran, Its Protein Conjugates, and Conjugates of Its Breakdown Products in Mice","display_name":"Immunogenic Properties of \u03b1(1 \u2192 6) Dextran, Its Protein Conjugates, and Conjugates of Its Breakdown Products in Mice","publication_year":1984,"publication_date":"1984-06-01","ids":{"openalex":"https://openalex.org/W2000491724","doi":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","mag":"2000491724","pmid":"https://pubmed.ncbi.nlm.nih.gov/6204375"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-3083.1984.tb00965.x","doi":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","pdf_url":null,"source":{"id":"https://openalex.org/S79173686","display_name":"Scandinavian Journal of Immunology","issn_l":"0300-9475","issn":["0300-9475","1365-3083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063528963","display_name":"O. M\u00e4kel\u00e4","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","FI"],"is_corresponding":true,"raw_author_name":"O. M\u00c4KEL\u00c4","raw_affiliation_strings":["Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","Human Institute, Go\u0308do\u0308llo\u0308, Hungary","Research Division, Pharmacia AB, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Human Institute, Go\u0308do\u0308llo\u0308, Hungary","institution_ids":[]},{"raw_affiliation_string":"Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000253992","display_name":"Ferenc P\u00e9terfy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","FI"],"is_corresponding":false,"raw_author_name":"F. P\u00c9TERFY","raw_affiliation_strings":["Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","Human Institute, Go\u0308do\u0308llo\u0308, Hungary","Research Division, Pharmacia AB, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Human Institute, Go\u0308do\u0308llo\u0308, Hungary","institution_ids":[]},{"raw_affiliation_string":"Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082686068","display_name":"I. G. OUTSCHOORN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","FI"],"is_corresponding":false,"raw_author_name":"I. G. OUTSCHOORN","raw_affiliation_strings":["Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","Human Institute, Go\u0308do\u0308llo\u0308, Hungary","Research Division, Pharmacia AB, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Human Institute, Go\u0308do\u0308llo\u0308, Hungary","institution_ids":[]},{"raw_affiliation_string":"Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091199023","display_name":"Ary Wolfgang Richter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","FI"],"is_corresponding":false,"raw_author_name":"A. W. RICHTER","raw_affiliation_strings":["Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","Human Institute, Go\u0308do\u0308llo\u0308, Hungary","Research Division, Pharmacia AB, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Human Institute, Go\u0308do\u0308llo\u0308, Hungary","institution_ids":[]},{"raw_affiliation_string":"Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002029171","display_name":"Ilkka Sepp\u00e4l\u00e4","orcid":"https://orcid.org/0000-0002-5595-2573","observed_orcids":["https://orcid.org/0000-0002-5595-2573"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","FI"],"is_corresponding":false,"raw_author_name":"I. SEPP\u00c4L\u00c4","raw_affiliation_strings":["Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","Human Institute, Go\u0308do\u0308llo\u0308, Hungary","Research Division, Pharmacia AB, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland; Human Institute, Go\u0308do\u0308llo\u0308, Hungary; Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain; and Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Department of Preventive Medicine, School of Medicine, Autonomous University of Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Human Institute, Go\u0308do\u0308llo\u0308, Hungary","institution_ids":[]},{"raw_affiliation_string":"Research Division, Pharmacia AB, Uppsala, Sweden","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5063528963"],"corresponding_institution_ids":["https://openalex.org/I133731052","https://openalex.org/I63634437"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":1.4501,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.82213972,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"19","issue":"6","first_page":"541","last_page":"550"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.08780000358819962,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.06480000168085098,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunogenicity","display_name":"immunogenicity","score":0.8100000023841858},{"id":"https://openalex.org/keywords/protein-conjugates","display_name":"protein conjugates","score":0.8420000076293945},{"id":"https://openalex.org/keywords/bovine-serum-albumin","display_name":"bovine serum albumin","score":1.0},{"id":"https://openalex.org/keywords/molecular-weight","display_name":"molecular weight","score":0.6919999718666077},{"id":"https://openalex.org/keywords/secondary-immune-response","display_name":"secondary immune response","score":0.75},{"id":"https://openalex.org/keywords/carrier-proteins","display_name":"carrier proteins","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C2777339698","wikidata":"https://www.wikidata.org/wiki/Q423123","display_name":"Dextran","level":2,"score":0.9111496806144714},{"id":"https://openalex.org/C2779026604","wikidata":"https://www.wikidata.org/wiki/Q4774742","display_name":"Antigenicity","level":3,"score":0.7924576997756958},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.763238787651062},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.6830281019210815},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.6681451797485352},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.6666203737258911},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6453722715377808},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5683311223983765},{"id":"https://openalex.org/C165616093","wikidata":"https://www.wikidata.org/wiki/Q424232","display_name":"Serum albumin","level":2,"score":0.4761766791343689},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.4415145218372345},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.4409415125846863},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.42019641399383545},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39567792415618896},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.35448700189590454},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34795308113098145},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22870498895645142},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20973986387252808},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.07821455597877502},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003911","descriptor_name":"Dextrans","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005620","descriptor_name":"Freund's Adjuvant","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006241","descriptor_name":"Haptens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008808","descriptor_name":"Mice, Inbred CBA","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012710","descriptor_name":"Serum Albumin, Bovine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-3083.1984.tb00965.x","doi":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3083.1984.tb00965.x","pdf_url":null,"source":{"id":"https://openalex.org/S79173686","display_name":"Scandinavian Journal of Immunology","issn_l":"0300-9475","issn":["0300-9475","1365-3083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:6204375","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6204375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of immunology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.766700029373169,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1483463638","https://openalex.org/W1515542131","https://openalex.org/W1525006592","https://openalex.org/W1550278711","https://openalex.org/W1575380681","https://openalex.org/W1596954795","https://openalex.org/W1598135222","https://openalex.org/W1807470715","https://openalex.org/W1907165492","https://openalex.org/W1928693942","https://openalex.org/W2006890583","https://openalex.org/W2027221386","https://openalex.org/W2027320836","https://openalex.org/W2055339494","https://openalex.org/W2062897864","https://openalex.org/W2087220023","https://openalex.org/W2091048996","https://openalex.org/W2100109550","https://openalex.org/W2120977313","https://openalex.org/W2157067263","https://openalex.org/W2169253475","https://openalex.org/W2305139664","https://openalex.org/W2468477668","https://openalex.org/W4211104534","https://openalex.org/W4248131889","https://openalex.org/W6634693588"],"related_works":["https://openalex.org/W1512191701","https://openalex.org/W1994862922","https://openalex.org/W2036939708","https://openalex.org/W2074878706","https://openalex.org/W2062897864","https://openalex.org/W2417889967","https://openalex.org/W2399154186","https://openalex.org/W2023765341","https://openalex.org/W1574077620","https://openalex.org/W2403464833"],"abstract_inverted_index":{"Mice":[0],"were":[1,46],"immunized":[2],"with":[3],"alpha":[4],"(1-6)":[5],"dextran,":[6],"either":[7],"as":[8],"such":[9],"or":[10],"coupled":[11,58,74,90,105],"to":[12,59,75,91,119,137],"protein":[13,62],"carriers,":[14],"and":[15,25],"their":[16],"anti-dextran":[17],"response":[18],"was":[19,37,67,142,149],"measured":[20],"by":[21],"a":[22,49,103],"solid-phase":[23],"radioimmunoassay":[24],"the":[26,114,125,128,132,143,150],"Farr":[27],"assay.":[28],"Like":[29],"earlier":[30],"investigators":[31],"we":[32],"found":[33],"that":[34,47],"protein-conjugated":[35],"dextran":[36,55,73,107],"more":[38,70],"antigenic":[39,61,71,77],"than":[40,72,101],"plain":[41],"dextran.":[42,129],"Our":[43],"novel":[44],"findings":[45],"(1)":[48],"standard":[50],"dose":[51],"(30":[52],"micrograms":[53],"of":[54,84,113,127,131],"per":[56],"injection)":[57],"strongly":[60],"(chicken":[63],"serum":[64,79],"albumin":[65,80],"(CSA)":[66],"three":[68],"times":[69,97],"weakly":[76],"bovine":[78],"(BSA);":[81],"(2)":[82],"dextrans":[83],"low":[85],"molecular":[86],"weight":[87],"(1000-10,000":[88],"daltons)":[89],"CSA":[92,148],"induced":[93],"at":[94],"least":[95],"ten":[96],"stronger":[98],"secondary":[99],"responses":[100],"did":[102],"similarly":[104],"macromolecular":[106],"(5-40":[108],"million":[109],"daltons);":[110],"(3)":[111],"variation":[112],"CHO/protein":[115],"ratio":[116,133],"from":[117,134],"0.3":[118],"1":[120],"had":[121],"little":[122],"effect":[123],"on":[124],"antigenicity":[126],"Increase":[130],"one":[135],"appeared":[136],"decrease":[138],"immunogenicity":[139],"when":[140,147],"BSA":[141],"carrier":[144],"but":[145],"not":[146],"carrier.":[151]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}