{"id":"https://openalex.org/W2000480955","doi":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","title":"Brittle nails and dyspareunia as first clues to recurrences of malignant glucagonoma","display_name":"Brittle nails and dyspareunia as first clues to recurrences of malignant glucagonoma","publication_year":2002,"publication_date":"2002-06-01","ids":{"openalex":"https://openalex.org/W2000480955","doi":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","mag":"2000480955","pmid":"https://pubmed.ncbi.nlm.nih.gov/12072081"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2133.2002.04673.x","doi":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111866838","display_name":"S-C. Chao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158999","display_name":"National Cheng Kung University Hospital","ror":"https://ror.org/04zx3rq17","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210158999"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"S-C. Chao","raw_affiliation_strings":["Department of Dermatology, National Cheng-Kung University Hospital, 138 Sheng-Li Road, 704 Tainan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, National Cheng-Kung University Hospital, 138 Sheng-Li Road, 704 Tainan, Taiwan","institution_ids":["https://openalex.org/I4210158999"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078304327","display_name":"J.Y\u2010Y. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158999","display_name":"National Cheng Kung University Hospital","ror":"https://ror.org/04zx3rq17","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210158999"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"J.y-Y. Lee","raw_affiliation_strings":["Department of Dermatology, National Cheng\u2010Kung University Hospital, 138 Sheng\u2010Li Road, 704 Tainan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, National Cheng\u2010Kung University Hospital, 138 Sheng\u2010Li Road, 704 Tainan, Taiwan","institution_ids":["https://openalex.org/I4210158999"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078304327"],"corresponding_institution_ids":["https://openalex.org/I4210158999"],"apc_list":{"value":3731,"currency":"GBP","value_usd":4920},"apc_paid":null,"fwci":1.807,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.83371967,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"146","issue":"6","first_page":"1071","last_page":"1074"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.08079999685287476,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucagonoma-syndrome","display_name":"glucagonoma syndrome","score":0.9679999947547913},{"id":"https://openalex.org/keywords/brittle-nails","display_name":"brittle nails","score":0.9390000104904175},{"id":"https://openalex.org/keywords/onychoschizia","display_name":"onychoschizia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/dyspareunia","display_name":"dyspareunia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/paraneoplastic-syndrome","display_name":"paraneoplastic syndrome","score":0.9380000233650208},{"id":"https://openalex.org/keywords/necrolytic-migratory-erythema","display_name":"necrolytic migratory erythema","score":0.9559999704360962},{"id":"https://openalex.org/keywords/genital-mucosa","display_name":"genital mucosa","score":0.6010000109672546},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.9409999847412109}],"concepts":[{"id":"https://openalex.org/C2777127409","wikidata":"https://www.wikidata.org/wiki/Q770843","display_name":"Glucagonoma","level":4,"score":0.9670652151107788},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.7161265015602112},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6944665908813477},{"id":"https://openalex.org/C2908748658","wikidata":"https://www.wikidata.org/wiki/Q776790","display_name":"Hyperglucagonemia","level":4,"score":0.41083961725234985},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1931239366531372},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.10021525621414185},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.088329017162323}],"mesh":[{"descriptor_ui":"D004414","descriptor_name":"Dyspareunia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005935","descriptor_name":"Glucagonoma","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005935","descriptor_name":"Glucagonoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009260","descriptor_name":"Nail Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1365-2133.2002.04673.x","doi":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2133.2002.04673.x","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},{"id":"pmid:12072081","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12072081","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of dermatology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W9986852","https://openalex.org/W1971751603","https://openalex.org/W2022447829","https://openalex.org/W2029911916","https://openalex.org/W2033632804","https://openalex.org/W2074728622","https://openalex.org/W2099407153","https://openalex.org/W2327424434","https://openalex.org/W2796382051","https://openalex.org/W4234458808","https://openalex.org/W4243633629"],"related_works":["https://openalex.org/W1977229346","https://openalex.org/W2011819643","https://openalex.org/W4254865846","https://openalex.org/W1999906595","https://openalex.org/W2108222929","https://openalex.org/W2059308278","https://openalex.org/W3000676715","https://openalex.org/W2062129097","https://openalex.org/W4386856839","https://openalex.org/W145901915"],"abstract_inverted_index":{"Glucagonoma":[0],"syndrome":[1,5,42,76,103,107],"is":[2,62],"a":[3,38],"paraneoplastic":[4],"in":[6,33,43,74,99,108],"which":[7,44],"the":[8,13,20,23,51,53,57,65,90,94,109],"occurrence":[9],"and":[10,28,48,69,96,104,114],"resolution":[11],"of":[12,22,40,56,59,67,92,112],"characteristic":[14],"necrolytic":[15],"migratory":[16],"erythema":[17],"lesions":[18],"parallel":[19],"course":[21],"underlying":[24],"glucagonoma.":[25,60],"Nail":[26],"abnormalities":[27],"dyspareunia":[29,49,70],"are":[30],"rarely":[31],"reported":[32],"this":[34,106],"syndrome.":[35],"We":[36],"describe":[37],"case":[39,88],"glucagonoma":[41,75,102],"recurrent":[45],"brittle":[46],"nails":[47],"gave":[50],"patient":[52],"first":[54],"clues":[55],"recurrence":[58],"It":[61],"possible":[63],"that":[64],"significance":[66],"onychoschizia":[68,113],"has":[71],"been":[72],"overlooked":[73],"because":[77],"patients":[78,100],"might":[79],"not":[80],"report":[81],"these":[82],"problems":[83],"to":[84],"their":[85],"doctors.":[86],"Our":[87],"illustrates":[89],"importance":[91],"examining":[93],"nail":[95],"genital":[97],"mucosa":[98],"with":[101],"including":[105],"differential":[110],"diagnosis":[111],"dyspareunia.":[115]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}