{"id":"https://openalex.org/W2000445811","doi":"https://doi.org/10.1007/s00726-015-1928-y","title":"Enhancing tumor-specific intracellular delivering efficiency of cell-penetrating peptide by fusion with a peptide targeting to EGFR","display_name":"Enhancing tumor-specific intracellular delivering efficiency of cell-penetrating peptide by fusion with a peptide targeting to EGFR","publication_year":2015,"publication_date":"2015-02-05","ids":{"openalex":"https://openalex.org/W2000445811","doi":"https://doi.org/10.1007/s00726-015-1928-y","mag":"2000445811","pmid":"https://pubmed.ncbi.nlm.nih.gov/25655386"},"language":"en","primary_location":{"id":"doi:10.1007/s00726-015-1928-y","doi":"https://doi.org/10.1007/s00726-015-1928-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00726-015-1928-y","pdf_url":null,"source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000445811"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Long The Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Long The Nguyen","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","East China University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"East China University of Science and Technology","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029715494","display_name":"Xuzhong Yang","orcid":"https://orcid.org/0000-0001-6654-0294","observed_orcids":["https://orcid.org/0000-0001-6654-0294"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu-Zhong Yang","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","Zhejiang Reachall Pharmaceutical Co. Ltd., 209 West Hulian Road, Dongyang, 322100, Zhejiang, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"Zhejiang Reachall Pharmaceutical Co. Ltd., 209 West Hulian Road, Dongyang, 322100, Zhejiang, China","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068460253","display_name":"Xuan Du","orcid":"https://orcid.org/0000-0001-9589-3566","observed_orcids":["https://orcid.org/0000-0001-9589-3566"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuan Du","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100388757","display_name":"Jiawei Wang","orcid":"https://orcid.org/0000-0001-9893-8539","observed_orcids":["https://orcid.org/0000-0001-9893-8539"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia-Wei Wang","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rui Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Zhang","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109992959","display_name":"Jian Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Zhao","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","Shanghai University of Traditional Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"Shanghai University of Traditional Chinese Medicine","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100717598","display_name":"Fujun Wang","orcid":"https://orcid.org/0000-0002-2851-6709","observed_orcids":["https://orcid.org/0000-0002-2851-6709"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fu-Jun Wang","raw_affiliation_strings":["Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, Shanghai, China","Zhejiang Reachall Pharmaceutical Co. Ltd., 209 West Hulian Road, Dongyang, 322100, Zhejiang, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]},{"raw_affiliation_string":"Zhejiang Reachall Pharmaceutical Co. Ltd., 209 West Hulian Road, Dongyang, 322100, Zhejiang, China","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021235960","display_name":"Yang Dong","orcid":"https://orcid.org/0000-0002-4810-2730","observed_orcids":["https://orcid.org/0000-0002-4810-2730"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Dong","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]},{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109111193","display_name":"Peng-Fei Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng-Fei Li","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering, Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100717598","https://openalex.org/A5109992959"],"corresponding_institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4210098460","https://openalex.org/I4391768089"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":0.7411,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.64819809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"47","issue":"5","first_page":"997","last_page":"1006"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-penetrating-peptides","display_name":"cell-penetrating peptides","score":1.0},{"id":"https://openalex.org/keywords/tat-peptide","display_name":"TAT peptide","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tumor-specific-delivery","display_name":"tumor-specific delivery","score":0.5009999871253967},{"id":"https://openalex.org/keywords/macropinocytosis","display_name":"macropinocytosis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/heparan-sulfate-proteoglycans","display_name":"heparan sulfate proteoglycans","score":0.9670000076293945},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.722000002861023},{"id":"https://openalex.org/keywords/tumor-cell-internalization","display_name":"tumor cell internalization","score":0.47699999809265137}],"concepts":[{"id":"https://openalex.org/C139770010","wikidata":"https://www.wikidata.org/wiki/Q1339807","display_name":"Internalization","level":3,"score":0.7915745973587036},{"id":"https://openalex.org/C2776929087","wikidata":"https://www.wikidata.org/wiki/Q189096","display_name":"Cell-penetrating peptide","level":3,"score":0.7733595371246338},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.6300360560417175},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.562959611415863},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49779224395751953},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4607589840888977},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.45011812448501587},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.43960919976234436},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.43859779834747314},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3674864172935486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30664628744125366},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3019370436668396},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21963584423065186}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010873","descriptor_name":"Pinocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014616","descriptor_name":"Vaccinia virus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019812","descriptor_name":"Heparan Sulfate Proteoglycans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019812","descriptor_name":"Heparan Sulfate Proteoglycans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057846","descriptor_name":"Cell-Penetrating Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057846","descriptor_name":"Cell-Penetrating Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057846","descriptor_name":"Cell-Penetrating Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00726-015-1928-y","doi":"https://doi.org/10.1007/s00726-015-1928-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00726-015-1928-y","pdf_url":null,"source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},{"id":"pmid:25655386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25655386","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino acids","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320698","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320335134","display_name":"National Institutes of Natural Sciences","ror":"https://ror.org/055n47h92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1973043879","https://openalex.org/W1973450171","https://openalex.org/W1974024530","https://openalex.org/W1981009270","https://openalex.org/W1983486105","https://openalex.org/W1997134006","https://openalex.org/W2001498530","https://openalex.org/W2001582257","https://openalex.org/W2003450660","https://openalex.org/W2007507285","https://openalex.org/W2009510319","https://openalex.org/W2031630601","https://openalex.org/W2039730697","https://openalex.org/W2055296721","https://openalex.org/W2056137958","https://openalex.org/W2056449387","https://openalex.org/W2072581984","https://openalex.org/W2080411977","https://openalex.org/W2098819770","https://openalex.org/W2103372572","https://openalex.org/W2111116820","https://openalex.org/W2113959082","https://openalex.org/W2119618139","https://openalex.org/W2127150853","https://openalex.org/W2157824687","https://openalex.org/W2158784355","https://openalex.org/W2168704422","https://openalex.org/W2172260616","https://openalex.org/W2335699992"],"related_works":["https://openalex.org/W2781629359","https://openalex.org/W2534896825","https://openalex.org/W2554185292","https://openalex.org/W2028033675","https://openalex.org/W3014699470","https://openalex.org/W2095482617","https://openalex.org/W2960639892","https://openalex.org/W2081435476","https://openalex.org/W3213557594"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}