{"id":"https://openalex.org/W2000402003","doi":"https://doi.org/10.1182/blood.v97.9.2695","title":"HIV-specific effector cytotoxic T lymphocytes and HIV-producing cells colocalize in white pulps and germinal centers from infected patients","display_name":"HIV-specific effector cytotoxic T lymphocytes and HIV-producing cells colocalize in white pulps and germinal centers from infected patients","publication_year":2001,"publication_date":"2001-05-01","ids":{"openalex":"https://openalex.org/W2000402003","doi":"https://doi.org/10.1182/blood.v97.9.2695","mag":"2000402003","pmid":"https://pubmed.ncbi.nlm.nih.gov/11313260"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v97.9.2695","doi":"https://doi.org/10.1182/blood.v97.9.2695","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v97.9.2695","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043801077","display_name":"Anne Hosmalin","orcid":"https://orcid.org/0000-0001-9021-3488","observed_orcids":["https://orcid.org/0000-0001-9021-3488"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne Hosmalin","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039199570","display_name":"Assia Samri","orcid":"https://orcid.org/0000-0002-2610-9915","observed_orcids":["https://orcid.org/0000-0002-2610-9915"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Assia Samri","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051808648","display_name":"Marie-Jeanne Dumaurier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Jeanne Dumaurier","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033424953","display_name":"Yasmine Dudoit","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yasmine Dudoit","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001231520","display_name":"\u00c9ric Oksenhendler","orcid":"https://orcid.org/0000-0001-8588-7138","observed_orcids":["https://orcid.org/0000-0001-8588-7138"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eric Oksenhendler","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055684572","display_name":"Marina Karmochkine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marina Karmochkine","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042701070","display_name":"Brigitte Autran","orcid":"https://orcid.org/0000-0002-3993-9336","observed_orcids":["https://orcid.org/0000-0002-3993-9336"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Brigitte Autran","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013201108","display_name":"Simon Wain\u2013Hobson","orcid":"https://orcid.org/0000-0002-6406-3858","observed_orcids":["https://orcid.org/0000-0002-6406-3858"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Simon Wain-Hobson","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011718115","display_name":"R\u00e9mi Cheynier","orcid":"https://orcid.org/0000-0003-1146-660X","observed_orcids":["https://orcid.org/0000-0003-1146-660X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I4405277234","display_name":"Laboratoire d'Immunologie Cellulaire et Tissulaire","ror":"https://ror.org/01zek2y46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405277234"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Re\u0301mi Cheynier","raw_affiliation_strings":["From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Unite\u0301 INSERM 445, Institut Cochin de Ge\u0301ne\u0301tique Mole\u0301culaire; Laboratoire d'Immunologie Cellulaire et Tissulaire, Ho\u0302pital de la Pitie\u0301-Salpe\u0302trie\u0300re; Unite\u0301 de Re\u0301trovirologie Mole\u0301culaire, Institut Pasteur; Service d'Immuno-He\u0301matologie, Ho\u0302pital St Louis; and Service d'Immunologie Clinique, Ho\u0302pital Europe\u0301en Georges Pompidou; all of Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210102325","https://openalex.org/I4210121705","https://openalex.org/I4210141964","https://openalex.org/I4210144610","https://openalex.org/I4405277234"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":1.4506,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.7904,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"97","issue":"9","first_page":"2695","last_page":"2701"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-specific-cytotoxic-t-lymphocytes","display_name":"HIV-specific cytotoxic T lymphocytes","score":0.8970000147819519},{"id":"https://openalex.org/keywords/splenic-white-pulp","display_name":"splenic white pulp","score":0.7590000033378601},{"id":"https://openalex.org/keywords/cd8-t-cell-activation","display_name":"CD8+ T cell activation","score":0.7720000147819519},{"id":"https://openalex.org/keywords/hiv-reservoir","display_name":"HIV reservoir","score":0.38199999928474426},{"id":"https://openalex.org/keywords/hiv-1-dna","display_name":"HIV-1 DNA","score":0.5329999923706055},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.7710000276565552},{"id":"https://openalex.org/keywords/secondary-lymphoid-organs","display_name":"secondary lymphoid organs","score":0.6959999799728394},{"id":"https://openalex.org/keywords/hiv-pathogenesis","display_name":"HIV pathogenesis","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C96926380","wikidata":"https://www.wikidata.org/wiki/Q1737968","display_name":"Germinal center","level":4,"score":0.756909966468811},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.7216851711273193},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6614177227020264},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5615876913070679},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.5226590037345886},{"id":"https://openalex.org/C147969180","wikidata":"https://www.wikidata.org/wiki/Q5014579","display_name":"CTL*","level":4,"score":0.521476149559021},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5208585858345032},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49883389472961426},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.48477691411972046},{"id":"https://openalex.org/C2779968557","wikidata":"https://www.wikidata.org/wiki/Q12646459","display_name":"Granzyme A","level":5,"score":0.43990713357925415},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3839848041534424},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.20425137877464294},{"id":"https://openalex.org/C2780380082","wikidata":"https://www.wikidata.org/wiki/Q12646460","display_name":"Granzyme B","level":4,"score":0.17832159996032715},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.13394522666931152},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.11914384365081787},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.11449876427650452},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood.v97.9.2695","doi":"https://doi.org/10.1182/blood.v97.9.2695","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v97.9.2695","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:11313260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11313260","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04008501v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04008501","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Blood, 2001, 97 (9), pp.2695-2701. ⟨10.1182/blood.v97.9.2695⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8299999833106995,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W204100860","https://openalex.org/W275674812","https://openalex.org/W1481708591","https://openalex.org/W1486583343","https://openalex.org/W1489800389","https://openalex.org/W1555983429","https://openalex.org/W1562534199","https://openalex.org/W1571842523","https://openalex.org/W1601810440","https://openalex.org/W1655510925","https://openalex.org/W1829099663","https://openalex.org/W1966299634","https://openalex.org/W1969899610","https://openalex.org/W1975057702","https://openalex.org/W1985346868","https://openalex.org/W1987369827","https://openalex.org/W1994476715","https://openalex.org/W2000745208","https://openalex.org/W2003227439","https://openalex.org/W2012139740","https://openalex.org/W2024054409","https://openalex.org/W2026078176","https://openalex.org/W2047269867","https://openalex.org/W2053187678","https://openalex.org/W2057575510","https://openalex.org/W2064502505","https://openalex.org/W2064896248","https://openalex.org/W2066792834","https://openalex.org/W2075135942","https://openalex.org/W2082639873","https://openalex.org/W2082814103","https://openalex.org/W2099188318","https://openalex.org/W2102342316","https://openalex.org/W2103182811","https://openalex.org/W2104978149","https://openalex.org/W2110401504","https://openalex.org/W2121196034","https://openalex.org/W2123742848","https://openalex.org/W2124969212","https://openalex.org/W2129114331","https://openalex.org/W2139257243","https://openalex.org/W2144882745","https://openalex.org/W2150492554","https://openalex.org/W2151303894","https://openalex.org/W2153977602","https://openalex.org/W2157622324","https://openalex.org/W2159256137","https://openalex.org/W2161737379","https://openalex.org/W2163715113","https://openalex.org/W2166072405","https://openalex.org/W2171282348","https://openalex.org/W2171933443","https://openalex.org/W2304190202","https://openalex.org/W2339173512","https://openalex.org/W6608240031"],"related_works":["https://openalex.org/W3092676535","https://openalex.org/W2324120656","https://openalex.org/W1549922507","https://openalex.org/W1605884721","https://openalex.org/W1985728487","https://openalex.org/W2032919665","https://openalex.org/W2102262438","https://openalex.org/W1974039875","https://openalex.org/W1556778776","https://openalex.org/W1896967685"],"abstract_inverted_index":{"Human":[0],"immunodeficiency":[1],"virus":[2],"(HIV)":[3],"infection":[4],"is":[5],"characterized":[6],"by":[7],"the":[8,43,194],"massive":[9],"infiltration":[10],"of":[11,45,56,69,91,100,209],"secondary":[12,210],"lymphoid":[13,106,211],"organs":[14,107,212],"with":[15,78,152],"activated":[16],"CD8(+)":[17],"T":[18,30],"lymphocytes.":[19],"While":[20],"converging":[21],"data":[22],"indicated":[23],"that":[24,203],"these":[25,218],"cells":[26,103],"were":[27,108,190],"HIV-specific":[28,46],"cytotoxic":[29],"lymphocytes":[31],"(CTLs)":[32],"responsible":[33],"for":[34,125],"HIV":[35,88],"spread":[36],"limitation,":[37],"direct":[38],"evidence":[39],"was":[40,49,129,139],"lacking.":[41],"Here,":[42],"presence":[44],"effector":[47,181,215],"CTLs":[48,216],"demonstrated":[50],"directly":[51],"ex":[52],"vivo":[53],"in":[54,67,104,112,116,131,142,167,171,193,206],"15":[55],"24":[57,70],"microdissected":[58],"splenic":[59],"white":[60,175,195],"pulps":[61,176,196],"from":[62,74,144],"an":[63],"untreated":[64],"patient":[65,77],"and":[66,93,114,169,173,197],"1":[68,111,115,170],"tonsil":[71],"germinal":[72,198],"centers":[73],"a":[75],"second":[76],"incomplete":[79],"viral":[80,120,127,155,187,204],"suppression":[81],"following":[82],"bitherapy.":[83],"These":[84,157],"patients":[85,146,158],"had":[86,159],"plasma":[87,154],"RNA":[89,122,189],"loads":[90],"5900":[92],"820":[94],"copies":[95],"per":[96],"milliliter.":[97],"The":[98],"frequencies":[99,165],"HIV-1":[101],"DNA(+)":[102,163],"their":[105],"more":[109],"than":[110],"50":[113],"175,":[117],"respectively.":[118],"Spliced":[119],"messenger":[121,188],"(a":[123],"marker":[124],"ongoing":[126],"replication)":[128],"present":[130],"most":[132],"immunocompetent":[133,207],"structures":[134,208],"tested.":[135],"Conversely,":[136],"CTL":[137,180],"activity":[138,182],"not":[140],"found":[141],"spleens":[143],"2":[145],"under":[147],"highly":[148],"active":[149],"antiretroviral":[150],"therapy,":[151],"undetectable":[153],"load.":[156],"much":[160],"lower":[161],"spleen":[162],"cell":[164],"(1":[166],"2700":[168],"3800)":[172],"no":[174],"containing":[177],"spliced":[178,186],"RNA.":[179],"as":[183,185],"well":[184],"both":[191],"concentrated":[192],"centers.":[199],"This":[200],"colocalization":[201],"indicates":[202],"replication":[205],"triggers":[213],"anti-HIV":[214],"to":[217,223],"particular":[219],"locations,":[220],"providing":[221],"clues":[222],"target":[224],"therapeutic":[225],"intervention.":[226]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}