{"id":"https://openalex.org/W2000386923","doi":"https://doi.org/10.1097/01.md.0000141096.00377.3f","title":"Acquired Methemoglobinemia: A Retrospective Series of 138 Cases at 2 Teaching Hospitals","display_name":"Acquired Methemoglobinemia: A Retrospective Series of 138 Cases at 2 Teaching Hospitals","publication_year":2004,"publication_date":"2004-08-31","ids":{"openalex":"https://openalex.org/W2000386923","doi":"https://doi.org/10.1097/01.md.0000141096.00377.3f","mag":"2000386923","pmid":"https://pubmed.ncbi.nlm.nih.gov/15342970"},"language":"en","primary_location":{"id":"doi:10.1097/01.md.0000141096.00377.3f","doi":"https://doi.org/10.1097/01.md.0000141096.00377.3f","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.md.0000141096.00377.3f","pdf_url":null,"source":{"id":"https://openalex.org/S28966261","display_name":"Medicine","issn_l":"0025-7974","issn":["0025-7974","1536-5964"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000386923"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019542428","display_name":"Rachel Ash\u2010Bernal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I2802697821","display_name":"Johns Hopkins Bayview Medical Center","ror":"https://ror.org/04pwc8466","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"id":"https://openalex.org/I4210129669","display_name":"Arnold P Gold Foundation","ror":"https://ror.org/035c70a92","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210129669"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel Ash-Bernal","raw_affiliation_strings":["From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","e-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","institution_ids":["https://openalex.org/I4210129669"]},{"raw_affiliation_string":"e-mail: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035047751","display_name":"Robert A. Wise","orcid":"https://orcid.org/0000-0002-8353-2349","observed_orcids":["https://orcid.org/0000-0002-8353-2349"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I2802697821","display_name":"Johns Hopkins Bayview Medical Center","ror":"https://ror.org/04pwc8466","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"id":"https://openalex.org/I4210129669","display_name":"Arnold P Gold Foundation","ror":"https://ror.org/035c70a92","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210129669"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Wise","raw_affiliation_strings":["Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","e-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","institution_ids":["https://openalex.org/I4210129669"]},{"raw_affiliation_string":"From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"e-mail: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089332726","display_name":"Scott Mitchell Wright","orcid":"https://orcid.org/0000-0002-3178-9193","observed_orcids":["https://orcid.org/0000-0002-3178-9193"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I2802697821","display_name":"Johns Hopkins Bayview Medical Center","ror":"https://ror.org/04pwc8466","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"id":"https://openalex.org/I4210129669","display_name":"Arnold P Gold Foundation","ror":"https://ror.org/035c70a92","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210129669"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott M. Wright","raw_affiliation_strings":["Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715; e-mail: [email\u00a0protected]","Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","e-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715; e-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Address reprint requests to: Scott M. Wright, MD, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224. Fax: 410-550-2715","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"Dr. Wright is an Arnold P. Gold Foundation Associate Professor of Medicine","institution_ids":["https://openalex.org/I4210129669"]},{"raw_affiliation_string":"From Divisions of General Internal Medicine (RAB, SMW) and Pulmonary Medicine (RW), Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821"]},{"raw_affiliation_string":"e-mail: [email\u00a0protected]","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5089332726"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I2802697821","https://openalex.org/I4210129669"],"apc_list":{"value":1950,"currency":"USD","value_usd":1950},"apc_paid":null,"fwci":3.8391,"has_fulltext":false,"cited_by_count":386,"citation_normalized_percentile":{"value":0.93333018,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"83","issue":"5","first_page":"265","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acquired-methemoglobinemia","display_name":"acquired methemoglobinemia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dapsone","display_name":"dapsone","score":0.8190000057220459},{"id":"https://openalex.org/keywords/benzocaine","display_name":"benzocaine","score":0.8149999976158142},{"id":"https://openalex.org/keywords/drug-induced-methemoglobinemia","display_name":"drug-induced methemoglobinemia","score":0.8619999885559082},{"id":"https://openalex.org/keywords/tissue-hypoxia","display_name":"tissue hypoxia","score":0.7620000243186951},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.6470000147819519},{"id":"https://openalex.org/keywords/co-oximetry","display_name":"co-oximetry","score":0.6869999766349792}],"concepts":[{"id":"https://openalex.org/C2777737778","wikidata":"https://www.wikidata.org/wiki/Q748442","display_name":"Methemoglobinemia","level":2,"score":0.9758893251419067},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9334737062454224},{"id":"https://openalex.org/C26865036","wikidata":"https://www.wikidata.org/wiki/Q416833","display_name":"Methemoglobin","level":3,"score":0.8748270869255066},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.5600219368934631},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5151178240776062},{"id":"https://openalex.org/C2777640609","wikidata":"https://www.wikidata.org/wiki/Q422226","display_name":"Dapsone","level":2,"score":0.4866653084754944},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3856184482574463},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.37530282139778137},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2686004936695099},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.2635493874549866},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25989753007888794},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003622","descriptor_name":"Dapsone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003622","descriptor_name":"Dapsone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005955","descriptor_name":"Glucosephosphate Dehydrogenase Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005955","descriptor_name":"Glucosephosphate Dehydrogenase Deficiency","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006784","descriptor_name":"Hospitals, Teaching","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008396","descriptor_name":"Maryland","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008706","descriptor_name":"Methemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008708","descriptor_name":"Methemoglobinemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008708","descriptor_name":"Methemoglobinemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008708","descriptor_name":"Methemoglobinemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010092","descriptor_name":"Oximetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.md.0000141096.00377.3f","doi":"https://doi.org/10.1097/01.md.0000141096.00377.3f","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.md.0000141096.00377.3f","pdf_url":null,"source":{"id":"https://openalex.org/S28966261","display_name":"Medicine","issn_l":"0025-7974","issn":["0025-7974","1536-5964"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine","raw_type":"journal-article"},{"id":"pmid:15342970","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15342970","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":116,"referenced_works":["https://openalex.org/W87743095","https://openalex.org/W96484744","https://openalex.org/W111386143","https://openalex.org/W195793742","https://openalex.org/W222564785","https://openalex.org/W306455475","https://openalex.org/W1556636234","https://openalex.org/W1696852410","https://openalex.org/W1964170531","https://openalex.org/W1965879602","https://openalex.org/W1966617775","https://openalex.org/W1969031819","https://openalex.org/W1970722876","https://openalex.org/W1971384618","https://openalex.org/W1972955432","https://openalex.org/W1974467982","https://openalex.org/W1977483417","https://openalex.org/W1978448435","https://openalex.org/W1978515416","https://openalex.org/W1984845481","https://openalex.org/W1987447189","https://openalex.org/W1988374784","https://openalex.org/W1990865456","https://openalex.org/W1991042120","https://openalex.org/W1991992428","https://openalex.org/W1993789334","https://openalex.org/W1997212497","https://openalex.org/W2001837257","https://openalex.org/W2004540034","https://openalex.org/W2006075565","https://openalex.org/W2012437327","https://openalex.org/W2013895772","https://openalex.org/W2015816334","https://openalex.org/W2019449116","https://openalex.org/W2021484012","https://openalex.org/W2024056426","https://openalex.org/W2028710946","https://openalex.org/W2028946283","https://openalex.org/W2034495440","https://openalex.org/W2036720845","https://openalex.org/W2036744362","https://openalex.org/W2039856561","https://openalex.org/W2040211231","https://openalex.org/W2043372194","https://openalex.org/W2046536315","https://openalex.org/W2049736491","https://openalex.org/W2049914089","https://openalex.org/W2050453675","https://openalex.org/W2051105907","https://openalex.org/W2052261958","https://openalex.org/W2053188361","https://openalex.org/W2055144403","https://openalex.org/W2055283699","https://openalex.org/W2056014240","https://openalex.org/W2056789701","https://openalex.org/W2056881585","https://openalex.org/W2057866669","https://openalex.org/W2063407207","https://openalex.org/W2065022999","https://openalex.org/W2065102252","https://openalex.org/W2066018481","https://openalex.org/W2068254387","https://openalex.org/W2068446549","https://openalex.org/W2073750440","https://openalex.org/W2078648961","https://openalex.org/W2078994967","https://openalex.org/W2081405104","https://openalex.org/W2081791283","https://openalex.org/W2083585884","https://openalex.org/W2084289711","https://openalex.org/W2092812367","https://openalex.org/W2093286532","https://openalex.org/W2100530900","https://openalex.org/W2102364869","https://openalex.org/W2105658737","https://openalex.org/W2111651820","https://openalex.org/W2116312230","https://openalex.org/W2120835549","https://openalex.org/W2124996084","https://openalex.org/W2140192771","https://openalex.org/W2143237635","https://openalex.org/W2153443115","https://openalex.org/W2154208672","https://openalex.org/W2163041688","https://openalex.org/W2164399367","https://openalex.org/W2165030054","https://openalex.org/W2167437946","https://openalex.org/W2254019113","https://openalex.org/W2265604032","https://openalex.org/W2296367030","https://openalex.org/W2313138152","https://openalex.org/W2323526592","https://openalex.org/W2338118750","https://openalex.org/W2342351290","https://openalex.org/W2347152633","https://openalex.org/W2396381569","https://openalex.org/W2397257079","https://openalex.org/W2398134736","https://openalex.org/W2399017506","https://openalex.org/W2403335790","https://openalex.org/W2406382545","https://openalex.org/W2407292083","https://openalex.org/W2411523893","https://openalex.org/W2418499853","https://openalex.org/W2419539404","https://openalex.org/W4233753542","https://openalex.org/W4241449706","https://openalex.org/W4242743693","https://openalex.org/W4244639006","https://openalex.org/W4248647793","https://openalex.org/W4248804120","https://openalex.org/W4255443484","https://openalex.org/W4301432476","https://openalex.org/W4302511953","https://openalex.org/W6830017120","https://openalex.org/W7214152351"],"related_works":["https://openalex.org/W1982895886","https://openalex.org/W4392877769","https://openalex.org/W4388795147","https://openalex.org/W4403287136","https://openalex.org/W7140145132","https://openalex.org/W3210768222","https://openalex.org/W1979575886","https://openalex.org/W2506751819","https://openalex.org/W2378147254","https://openalex.org/W4310396496"],"abstract_inverted_index":{"Methemoglobin":[0],"is":[1,14,250],"a":[2,29,110,195,251,264],"form":[3],"of":[4,37,91,113,127,149,155,170,200,267],"hemoglobin":[5],"that":[6,234,254,263],"does":[7],"not":[8],"bind":[9],"oxygen.":[10],"When":[11],"its":[12],"concentration":[13],"elevated":[15,177],"in":[16,124,240,271],"red":[17],"blood":[18],"cells,":[19],"functional":[20],"anemia":[21],"and":[22,44,57,85,105,135,244,258,274,286],"tissue":[23],"hypoxia":[24],"may":[25],"occur.":[26],"We":[27,64,74,261],"performed":[28],"retrospective":[30],"case":[31],"series":[32],"to":[33,69,80,119,141,216,282],"describe":[34],"the":[35,45,82,97,106,128,145,171,174,191,242,245,280,284],"cases":[36,90],"acquired":[38,92,150,236],"methemoglobinemia":[39,93,206,230,237,249,268],"(methemoglobin":[40],"level":[41,162,199],">2%)":[42],"detected":[43,95],"clinical":[46,83],"circumstances":[47],"under":[48],"which":[49],"they":[50],"occurred":[51,108,123],"at":[52],"2":[53],"tertiary":[54],"care":[55],"hospitals":[56],"affiliated":[58],"outpatient":[59,131,246],"clinics":[60],"over":[61,96,109],"28":[62,98],"months.":[63,99],"surveyed":[65],"co-oximetry":[66],"laboratory":[67],"data":[68],"identify":[70],"patients":[71,172,204,228],"with":[72,173,194,223,229,289],"methemoglobinemia.":[73,142],"reviewed":[75],"these":[76,164],"patients'":[77],"medical":[78],"records":[79],"extract":[81],"information":[84],"context.":[86],"One":[87,133],"hundred":[88],"thirty-eight":[89],"were":[94,138,231],"There":[100],"was":[101,144,166,190],"no":[102],"gender":[103],"predisposition,":[104],"condition":[107,253],"wide":[111],"range":[112],"ages":[114],"(patients":[115],"aged":[116],"4":[117],"days":[118],"86":[120],"years).":[121],"Cases":[122],"many":[125],"areas":[126],"hospital,":[129],"including":[130],"clinics.":[132],"fatality":[134],"3":[136],"near-fatalities":[137],"directly":[139],"attributable":[140],"Dapsone":[143],"most":[146,175],"common":[147],"etiology":[148],"methemoglobinemia,":[151],"accounting":[152],"for":[153],"42%":[154],"all":[156,226],"cases.":[157],"The":[158],"mean":[159,196],"peak":[160,197],"methemoglobin":[161,198],"among":[163],"individuals":[165],"7.6%.":[167],"In":[168],"5":[169],"severely":[176],"levels,":[178],"20%":[179],"benzocaine":[180],"spray":[181],"(Hurricaine":[182],"Topical":[183],"Anesthetic":[184],"spray,":[185],"Beutlich":[186],"Pharmaceuticals,":[187],"Waukegan,":[188],"IL)":[189],"etiology,":[192],"associated":[193,288],"43.8%.":[201],"Eleven":[202],"pediatric":[203],"developed":[205],"either":[207],"from":[208],"exogenous":[209],"exposure,":[210],"such":[211,219],"as":[212,220],"drugs,":[213],"or":[214],"due":[215],"serious":[217],"illness,":[218],"gastrointestinal":[221],"infections":[222],"dehydration.":[224],"Almost":[225],"(94%)":[227],"anemic.":[232],"Drugs":[233],"cause":[235],"are":[238],"ubiquitous":[239],"both":[241],"hospital":[243],"setting.":[247],"Acquired":[248],"treatable":[252],"causes":[255],"significant":[256],"morbidity":[257,285],"even":[259],"mortality.":[260],"hope":[262],"heightened":[265],"awareness":[266],"will":[269],"result":[270],"improved":[272],"recognition":[273],"treatment.":[275],"Primary":[276],"prevention":[277],"efforts":[278],"have":[279],"potential":[281],"reduce":[283],"mortality":[287],"this":[290],"condition.":[291]},"counts_by_year":[{"year":2026,"cited_by_count":25},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":24},{"year":2021,"cited_by_count":30},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":21},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}