{"id":"https://openalex.org/W2000358947","doi":"https://doi.org/10.1016/0142-9612(95)00349-5","title":"Gamma sterilization of UHMWPE articular implants: an analysis of the oxidation problem","display_name":"Gamma sterilization of UHMWPE articular implants: an analysis of the oxidation problem","publication_year":1996,"publication_date":"1996-09-01","ids":{"openalex":"https://openalex.org/W2000358947","doi":"https://doi.org/10.1016/0142-9612(95)00349-5","mag":"2000358947","pmid":"https://pubmed.ncbi.nlm.nih.gov/8879511"},"language":"en","primary_location":{"id":"doi:10.1016/0142-9612(95)00349-5","doi":"https://doi.org/10.1016/0142-9612(95)00349-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0142-9612(95)00349-5","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091035993","display_name":"V. Premnath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. Premnath","raw_affiliation_strings":["Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA","Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069298267","display_name":"William Hamilton Harris","orcid":"https://orcid.org/0000-0002-2650-1132","observed_orcids":["https://orcid.org/0000-0002-2650-1132"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W.H. Harris","raw_affiliation_strings":["Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","Orthopedic Biomechanics Laboratory, Massachusetts General Hospital, Jackson 1126, 32 Fruit Street, Boston, MA 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Orthopedic Biomechanics Laboratory, Massachusetts General Hospital, Jackson 1126, 32 Fruit Street, Boston, MA 02114, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059943427","display_name":"Murali Jasty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Jasty","raw_affiliation_strings":["Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","Orthopedic Biomechanics Laboratory, Massachusetts General Hospital, Jackson 1126, 32 Fruit Street, Boston, MA 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Orthopedic Biomechanics Laboratory, Massachusetts General Hospital, Jackson 1126, 32 Fruit Street, Boston, MA 02114, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028655872","display_name":"Edward W. Merrill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"E.W. Merrill","raw_affiliation_strings":["Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Program in Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5028655872"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":10.1506,"has_fulltext":false,"cited_by_count":389,"citation_normalized_percentile":{"value":0.98539308,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"17","issue":"18","first_page":"1741","last_page":"1753"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10512","display_name":"Orthopaedic implants and arthroplasty","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10512","display_name":"Orthopaedic implants and arthroplasty","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-irradiation","display_name":"gamma irradiation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/ultra-high-molecular-weight-polyethylene","display_name":"ultra-high molecular weight polyethylene","score":0.9399999976158142},{"id":"https://openalex.org/keywords/radiation-sterilization","display_name":"radiation sterilization","score":0.6859999895095825},{"id":"https://openalex.org/keywords/polymer-oxidation","display_name":"polymer oxidation","score":0.6259999871253967},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.8889999985694885},{"id":"https://openalex.org/keywords/oxygen-diffusion","display_name":"oxygen diffusion","score":0.953000009059906},{"id":"https://openalex.org/keywords/polymer-permeability","display_name":"polymer permeability","score":0.7390000224113464},{"id":"https://openalex.org/keywords/chain-scission","display_name":"chain scission","score":0.8870000243186951},{"id":"https://openalex.org/keywords/orthopedic-implants","display_name":"orthopedic implants","score":0.8169999718666077},{"id":"https://openalex.org/keywords/mechanical-property-degradation","display_name":"mechanical property degradation","score":0.5989999771118164},{"id":"https://openalex.org/keywords/crystallinity","display_name":"crystallinity","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7024465203285217},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.6498913764953613},{"id":"https://openalex.org/C2779751980","wikidata":"https://www.wikidata.org/wiki/Q143429","display_name":"Polyethylene","level":2,"score":0.6488243341445923},{"id":"https://openalex.org/C3017806408","wikidata":"https://www.wikidata.org/wiki/Q92772955","display_name":"Gamma irradiation","level":3,"score":0.6092524528503418},{"id":"https://openalex.org/C148761745","wikidata":"https://www.wikidata.org/wiki/Q1563203","display_name":"Sterilization (economics)","level":4,"score":0.5908907651901245},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.5659796595573425},{"id":"https://openalex.org/C2776863617","wikidata":"https://www.wikidata.org/wiki/Q7115956","display_name":"Oxygen permeability","level":3,"score":0.5464954376220703},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5164949893951416},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.5052178502082825},{"id":"https://openalex.org/C2992026580","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Linear polymer","level":3,"score":0.42628660798072815},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.4035744369029999},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.37029677629470825},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.36241042613983154},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15136975049972534},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12359619140625},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C536366893","wikidata":"https://www.wikidata.org/wiki/Q66076","display_name":"Foreign exchange market","level":3,"score":0.0},{"id":"https://openalex.org/C556758197","wikidata":"https://www.wikidata.org/wiki/Q580018","display_name":"Monetary economics","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C2983132609","wikidata":"https://www.wikidata.org/wiki/Q66076","display_name":"Foreign exchange","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001704","descriptor_name":"Biopolymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005720","descriptor_name":"Gamma Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007595","descriptor_name":"Joint Prosthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011095","descriptor_name":"Polyethylenes","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D011126","descriptor_name":"Polypropylenes","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D013242","descriptor_name":"Sterilization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0142-9612(95)00349-5","doi":"https://doi.org/10.1016/0142-9612(95)00349-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0142-9612(95)00349-5","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:8879511","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8879511","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W35092612","https://openalex.org/W133336325","https://openalex.org/W242357373","https://openalex.org/W375459907","https://openalex.org/W566059251","https://openalex.org/W588298191","https://openalex.org/W652580087","https://openalex.org/W1491770830","https://openalex.org/W1568888205","https://openalex.org/W1913448074","https://openalex.org/W1935385781","https://openalex.org/W1966343066","https://openalex.org/W1985220301","https://openalex.org/W1988759341","https://openalex.org/W1989772611","https://openalex.org/W1996268093","https://openalex.org/W1998176801","https://openalex.org/W2002720597","https://openalex.org/W2003882571","https://openalex.org/W2011143025","https://openalex.org/W2011935497","https://openalex.org/W2013462032","https://openalex.org/W2032123454","https://openalex.org/W2053814022","https://openalex.org/W2058035170","https://openalex.org/W2060387729","https://openalex.org/W2064369312","https://openalex.org/W2064450878","https://openalex.org/W2069870315","https://openalex.org/W2076329513","https://openalex.org/W2082185897","https://openalex.org/W2085029482","https://openalex.org/W2086561996","https://openalex.org/W2091476007","https://openalex.org/W2097817983","https://openalex.org/W2098842842","https://openalex.org/W2104630188","https://openalex.org/W2130684144","https://openalex.org/W2149359743","https://openalex.org/W2154172753","https://openalex.org/W2225642542","https://openalex.org/W2256220430","https://openalex.org/W2292645706","https://openalex.org/W2316356153","https://openalex.org/W2330962412","https://openalex.org/W2410009831","https://openalex.org/W2988858604","https://openalex.org/W4246124642"],"related_works":["https://openalex.org/W378665776","https://openalex.org/W2072815554","https://openalex.org/W2283620726","https://openalex.org/W2088571528","https://openalex.org/W1952313127","https://openalex.org/W1999065914","https://openalex.org/W1967389358","https://openalex.org/W2122756727","https://openalex.org/W1980929223","https://openalex.org/W7220582006"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":27},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}