{"id":"https://openalex.org/W2000357107","doi":"https://doi.org/10.1038/modpathol.3880483","title":"Expression of Cytokeratin 5/6 in Epithelial Neoplasms: An Immunohistochemical Study of 509 Cases","display_name":"Expression of Cytokeratin 5/6 in Epithelial Neoplasms: An Immunohistochemical Study of 509 Cases","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2000357107","doi":"https://doi.org/10.1038/modpathol.3880483","mag":"2000357107","pmid":"https://pubmed.ncbi.nlm.nih.gov/11796835"},"language":"en","primary_location":{"id":"doi:10.1038/modpathol.3880483","doi":"https://doi.org/10.1038/modpathol.3880483","is_oa":true,"landing_page_url":"https://doi.org/10.1038/modpathol.3880483","pdf_url":"https://www.nature.com/articles/3880483.pdf","source":{"id":"https://openalex.org/S33606366","display_name":"Modern Pathology","issn_l":"0893-3952","issn":["0893-3952","1530-0285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern Pathology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000357107"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nature.com/articles/3880483.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113652607","display_name":"Peiguo G. Chu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peiguo G Chu","raw_affiliation_strings":["Department of Pathology, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA","Department of Pathology, City of Hope National Medical Center, Duarte, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA","institution_ids":["https://openalex.org/I1301076528"]},{"raw_affiliation_string":"Department of Pathology, City of Hope National Medical Center, Duarte, California","institution_ids":["https://openalex.org/I1301076528"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112182874","display_name":"Lawrence Martin Weiss","orcid":"https://orcid.org/0000-0002-2356-535X","observed_orcids":["https://orcid.org/0000-0002-2356-535X"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence M Weiss","raw_affiliation_strings":["Department of Pathology, City of Hope National Medical Center, Duarte, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, City of Hope National Medical Center, Duarte, California","institution_ids":["https://openalex.org/I1301076528"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1301076528"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":6.9711,"has_fulltext":true,"cited_by_count":259,"citation_normalized_percentile":{"value":0.97181409,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"6","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12379","display_name":"Cancer Diagnosis and Treatment","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ck5-6","display_name":"CK5/6","score":0.9940000176429749},{"id":"https://openalex.org/keywords/epithelial-tumors","display_name":"epithelial tumors","score":0.8809999823570251},{"id":"https://openalex.org/keywords/malignant-mesothelioma","display_name":"malignant mesothelioma","score":0.9480000138282776},{"id":"https://openalex.org/keywords/lung-adenocarcinoma","display_name":"lung adenocarcinoma","score":0.9169999957084656},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.7549999952316284},{"id":"https://openalex.org/keywords/pleural-metastasis","display_name":"pleural metastasis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/peritoneal-metastases","display_name":"peritoneal carcinomatosis","score":0.984000027179718},{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.8889999985694885},{"id":"https://openalex.org/keywords/basal-cell-carcinoma","display_name":"basal cell carcinoma","score":0.9070000052452087},{"id":"https://openalex.org/keywords/thymoma","display_name":"thymoma","score":0.9070000052452087},{"id":"https://openalex.org/keywords/salivary-gland-tumors","display_name":"salivary gland tumors","score":0.9259999990463257},{"id":"https://openalex.org/keywords/urothelial-carcinoma","display_name":"urothelial carcinoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/endometrial-adenocarcinoma","display_name":"endometrial adenocarcinoma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.9710000157356262},{"id":"https://openalex.org/keywords/breast-adenocarcinoma","display_name":"breast adenocarcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/ovarian-adenocarcinoma","display_name":"ovarian adenocarcinoma","score":0.9279999732971191},{"id":"https://openalex.org/keywords/immunohistochemical-markers","display_name":"immunohistochemical markers","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C2779012181","wikidata":"https://www.wikidata.org/wiki/Q2750567","display_name":"Cytokeratin","level":3,"score":0.8104733228683472},{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.7917396426200867},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.7779958844184875},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.7339802980422974},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6859771609306335},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.61847984790802},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4697962999343872},{"id":"https://openalex.org/C2776517811","wikidata":"https://www.wikidata.org/wiki/Q7204732","display_name":"Pleural disease","level":4,"score":0.4418531656265259},{"id":"https://openalex.org/C2779159893","wikidata":"https://www.wikidata.org/wiki/Q1429863","display_name":"Thymoma","level":2,"score":0.43046554923057556},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2813780605792999},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24847543239593506},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.21605902910232544},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17687076330184937}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007633","descriptor_name":"Keratins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007633","descriptor_name":"Keratins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053547","descriptor_name":"Keratin-14","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053552","descriptor_name":"Keratin-7","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053555","descriptor_name":"Keratin-5","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/modpathol.3880483","doi":"https://doi.org/10.1038/modpathol.3880483","is_oa":true,"landing_page_url":"https://doi.org/10.1038/modpathol.3880483","pdf_url":"https://www.nature.com/articles/3880483.pdf","source":{"id":"https://openalex.org/S33606366","display_name":"Modern Pathology","issn_l":"0893-3952","issn":["0893-3952","1530-0285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern Pathology","raw_type":"journal-article"},{"id":"pmid:11796835","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11796835","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/modpathol.3880483","doi":"https://doi.org/10.1038/modpathol.3880483","is_oa":true,"landing_page_url":"https://doi.org/10.1038/modpathol.3880483","pdf_url":"https://www.nature.com/articles/3880483.pdf","source":{"id":"https://openalex.org/S33606366","display_name":"Modern Pathology","issn_l":"0893-3952","issn":["0893-3952","1530-0285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Modern Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000357107.pdf","grobid_xml":"https://content.openalex.org/works/W2000357107.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W242742671","https://openalex.org/W1579881701","https://openalex.org/W1968312126","https://openalex.org/W1970720721","https://openalex.org/W1976318381","https://openalex.org/W1980118516","https://openalex.org/W1980701395","https://openalex.org/W2013790784","https://openalex.org/W2024832336","https://openalex.org/W2026019623","https://openalex.org/W2049415840","https://openalex.org/W2061527414","https://openalex.org/W2070913126","https://openalex.org/W2119505427","https://openalex.org/W2149782428","https://openalex.org/W2335078504","https://openalex.org/W2400857649","https://openalex.org/W4232029710"],"related_works":["https://openalex.org/W1980118516","https://openalex.org/W2077679103","https://openalex.org/W1789754851","https://openalex.org/W3200344127","https://openalex.org/W2038184877","https://openalex.org/W4389857321","https://openalex.org/W2049415840","https://openalex.org/W1995948106","https://openalex.org/W2067313017","https://openalex.org/W2144938808"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}